Fred R. Hirsch

14.2k total citations · 4 hit papers
136 papers, 8.2k citations indexed

About

Fred R. Hirsch is a scholar working on Pulmonary and Respiratory Medicine, Oncology and Molecular Biology. According to data from OpenAlex, Fred R. Hirsch has authored 136 papers receiving a total of 8.2k indexed citations (citations by other indexed papers that have themselves been cited), including 94 papers in Pulmonary and Respiratory Medicine, 64 papers in Oncology and 39 papers in Molecular Biology. Recurrent topics in Fred R. Hirsch's work include Lung Cancer Treatments and Mutations (84 papers), Lung Cancer Research Studies (34 papers) and Lung Cancer Diagnosis and Treatment (24 papers). Fred R. Hirsch is often cited by papers focused on Lung Cancer Treatments and Mutations (84 papers), Lung Cancer Research Studies (34 papers) and Lung Cancer Diagnosis and Treatment (24 papers). Fred R. Hirsch collaborates with scholars based in United States, China and Japan. Fred R. Hirsch's co-authors include Paul A. Bunn, Marileila Varella‐Garcia, Wilbur A. Franklin, Robert Veve, Roy M. Bremnes, Anna E. Barón, Chan Zeng, Michael V. Di Maria, Federico Cappuzzo and Kenichi Suda and has published in prestigious journals such as The Lancet, Journal of Clinical Oncology and PLoS ONE.

In The Last Decade

Fred R. Hirsch

131 papers receiving 8.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Epidermal Growth Factor Receptor in Non–Small-Cell Lung Carcinomas: Correlation Between Gene Copy Number and Protein Expression and Impact on Prognosis

2003 1.2k citations Fred R. Hirsch, Marileila Varella‐Garcia et al. profile →
Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer

2018 670 citations Matthew D. Hellmann, Margaret K. Callahan et al. Cancer Cell profile →
Increased Epidermal Growth Factor Receptor Gene Copy Number Is Associated With Poor Prognosis in Head and Neck Squamous Cell Carcinomas

2006 448 citations Marileila Varella‐Garcia, Fred R. Hirsch et al. profile →
New and emerging targeted treatments in advanced non-small-cell lung cancer

2016 359 citations Fred R. Hirsch, Kenichi Suda et al. profile →

Peers

Countries citing papers authored by Fred R. Hirsch

Since Specialization

Citations

This map shows the geographic impact of Fred R. Hirsch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fred R. Hirsch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fred R. Hirsch more than expected).

Fields of papers citing papers by Fred R. Hirsch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fred R. Hirsch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fred R. Hirsch. The network helps show where Fred R. Hirsch may publish in the future.

Co-authorship network of co-authors of Fred R. Hirsch

This figure shows the co-authorship network connecting the top 25 collaborators of Fred R. Hirsch. A scholar is included among the top collaborators of Fred R. Hirsch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fred R. Hirsch. Fred R. Hirsch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Emerging options and future strategies in immunotherapy for advanced lung squamous-cell carcinoma 2025 ·Annals of Oncology ·Yue Wang, (unknown), Fred R. Hirsch, Shun Lu, Ramaswamy Govindan, K. Park, Solange Peters, (unknown)	0
2	Comprehensive Immune Profiling of Medullary Thyroid Cancer 2020 ·Thyroid ·Nikita Pozdeyev, Timothy A. Erickson, Lian Zhang, Kim Ellison, Christopher J. Rivard, Sharon B. Sams, Fred R. Hirsch, Bryan R. Haugen, Jena D. French	39
3	Galectin-9 in non-small cell lung cancer 2019 ·Lung Cancer ·Yayi He, Keyi Jia, Rafał Dziadziuszko, Sha Zhao, Xiaoshen Zhang, Juan Deng, Hao Wang, Fred R. Hirsch, Caicun Zhou	36
4	c-MET as a biomarker in patients with surgically resected non-small cell lung cancer 2019 ·Lung Cancer ·Georgios Tsakonas, Johan Botling, Patrick Micke, Chris Rivard, (unknown), Johanna Sofia Margareta Mattsson, (unknown), Fred R. Hirsch, Simon Ekman	24
5	CD44 Facilitates Epithelial-to-Mesenchymal Transition Phenotypic Change at Acquisition of Resistance to EGFR Kinase Inhibitors in Lung Cancer 2018 ·Molecular Cancer Therapeutics ·Kenichi Suda, Isao Murakami, Hui Yu, Jihye Kim, Aik Choon Tan, Hiroshi Mizuuchi, Leslie Rozeboom, Kim Ellison, Christopher J. Rivard, Tetsuya Mitsudomi, Fred R. Hirsch	39
6	Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer breakdown → 2018 ·Cancer Cell ·Matthew D. Hellmann, Margaret K. Callahan, Mark M. Awad, Emiliano Calvo, Paolo A. Ascierto, Akin Atmaca, Naiyer A. Rizvi, Fred R. Hirsch, Giovanni Selvaggi, Joseph D. Szustakowski, Ariella Sasson, Ryan Golhar, Patrik Vitazka, Chang Han, William J. Geese, Scott Antonia	670
7	EGFR Gene Copy Number by FISH May Predict Outcome of Necitumumab in Squamous Lung Carcinomas: Analysis from the SQUIRE Study 2017 ·Journal of Thoracic Oncology ·Carlo Genova, Mark A. Socinski, Rebecca R. Hozak, Gu Mi, Raffael Kurek, Javad Shahidi, Luis Paz‐Ares, Nick Thatcher, Christopher J. Rivard, (unknown), Fred R. Hirsch	10
8	MA15.03 The Predictive Value of Mutation/Neoantigen Burden from ctDNA on the Efficacy of PD-1 Blockade in Advanced NSCLC 2017 ·Journal of Thoracic Oncology ·Weijing Cai, Caicun Zhou, Chunxia Su, Feng Wu, Shengxiang Ren, Xiaoxia Chen, Fred R. Hirsch	2
9	PS01.20: Immune Checkpoints Expression in Small Cell Lung Cancer Lines 2016 ·Journal of Thoracic Oncology ·Hui Yu, Yayi He, Christopher J. Rivard, Dan Chan, Dexiang Gao, Kim Ellison, (unknown), Kenichi Suda, Fred R. Hirsch	1
10	Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma 2015 ·Cancer Prevention Research ·Daniel T. Merrick, Dexiang Gao, York E. Miller, Robert L. Keith, Anna E. Barón, William J. Feser, Timothy C. Kennedy, Patrick J. Blatchford, (unknown), Fred R. Hirsch, Lynn E. Heasley, Paul A. Bunn, Wilbur A. Franklin	24
11	FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity across All Lung Cancer Histologies 2014 ·Clinical Cancer Research ·Murry W. Wynes, Trista K. Hinz, Dexiang Gao, Michael L. Martini, Lindsay A. Marek, Kathryn E. Ware, (unknown), Diana Böhm, Sven Perner, Barbara A. Helfrich, Rafał Dziadziuszko, Jacek Jassem, Szymon Wojtylak, Aleksandra Sejda, Joseph M. Gozgit, Paul A. Bunn, D. Ross Camidge, Aik Choon Tan, Fred R. Hirsch, Lynn E. Heasley	125
12	Detection of Circulating Lung Cancer Cells with Strong Thymidylate Synthase Reactivity in the Peripheral Blood of a Patient with Pulmonary Adenocarcinoma Treated with Pemetrexed 2012 ·Journal of Thoracic Oncology ·Daniel C. Christoph, Andreas-Claudius Hoffmann, Thomas Gauler, Bernadette Reyna Asuncion, (unknown), (unknown), (unknown), Cindy Tran, Murry W. Wynes, Martin Schüler, (unknown), Fred R. Hirsch	7
13	Thymidylate Synthase Protein Expression by IHC and Gene Copy Number by SISH Correlate and Show Great Variability in Non–Small Cell Lung Cancer 2012 ·Journal of Thoracic Oncology ·Murry W. Wynes, Krzysztof Konopa, Shalini Singh, (unknown), James Ranger‐Moore, (unknown), Daniel C. Christoph, Rafał Dziadziuszko, Jacek Jassem, Fred R. Hirsch	13
14	Novel Functional Germline Variants in the VEGF Receptor 2 Gene and Their Effect on Gene Expression and Microvessel Density in Lung Cancer 2011 ·Clinical Cancer Research ·Dylan M. Glubb, Elisa Cerri, (unknown), Wei Zhang, Osman Mirza, Emma E. Thompson, Peixian Chen, Soma Das, Jacek Jassem, Witold Rzyman, Mark W. Lingen, Ravi Salgia, Fred R. Hirsch, Rafał Dziadziuszko, Kurt Ballmer‐Hofer, Federico Innocenti	65
15	Development of an Integrated Genomic Classifier for a Novel Agent in Colorectal Cancer: Approach to Individualized Therapy in Early Development 2010 ·Clinical Cancer Research ·Todd M. Pitts, Aik Choon Tan, Gillian N. Kulikowski, John J. Tentler, Amy Brown, (unknown), Stephen Leong, Christopher D. Coldren, Fred R. Hirsch, Marileila Varella‐Garcia, Christopher Korch, Sabine Eckhardt	56
16	Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer 2009 ·Oncogene ·Fred R. Hirsch, Marileila Varella‐Garcia, Federico Cappuzzo	215
17	Baseline Gene Expression Predicts Sensitivity to Gefitinib in Non–Small Cell Lung Cancer Cell Lines 2006 ·Molecular Cancer Research ·Christopher D. Coldren, Barbara A. Helfrich, Samir E. Witta, Michio Sugita, Razvan Lapadat, Chan Zeng, (unknown), Wilbur A. Franklin, Fred R. Hirsch, Mark W. Geraci, Paul A. Bunn	107
18	Biological Markers for Non–Small Cell Lung Cancer Patient Selection for Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy 2006 ·Clinical Cancer Research ·Paul A. Bunn, Rafał Dziadziuszko, Marileila Varella‐Garcia, Wilbur A. Franklin, Samir E. Witta, Karen Kelly, Fred R. Hirsch	46
19	Early detection and prevention of lung cancer 2002 ·European Respiratory Review ·Kristiaan Nackaerts, Élisabeth Brambilla, Nico van Zandwijk, Katja Bromen, Stefan Diederich, Fred R. Hirsch, Rudolf M. Huber, Vincent Ninane, Francesco Leo, Luc Thiberville, Olav Axelson, Maurits Demedts, Benoît Nemery, Michel Petit, Stephen Spiro, Annie J. Sasco, Jan P. van Meerbeeck	2
20	An SDR standard: impetus, elements, and impediments 1973 ·Fred R. Hirsch	3

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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