Emilio Hirsch

27.3k citations

297 papers · 19.0k indexed · 5 hit papers · h-index 73

Impact in

Immunology and Allergy top 0.2%
- Cell Adhesion Molecules Research
Immunology top 0.2%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology

Papers in

Immunology and Allergy 32
- Cell Adhesion Molecules Research 31
Immunology 74
- Immune Cell Function and Interaction 15
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms 14

Co-authors: Fiorella Altruda Matthias P. Wymann Alessandra Ghigo Federico Gulluni Lorenzo Silengo Miriam Martini Maria Chiara De Santis Laura Braccini
Journals: Blood (13 papers)Cardiovascular Research (10 papers)Journal of Biological Chemistry (9 papers)Aesthetic Surgery Journal (8 papers)The Journal of Immunology (7 papers)
Partner nations: Italy United States Germany

In The Last Decade

Emilio Hirsch

290 papers receiving 18.8k citations

Hit Papers

5 papers align trajectories log scale

Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis 2016 · 341 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2016 Nature Cell Biology
2014 Annals of Medicine
2005 Nature Medicine
2002 Nature
2000 Science

Peers

Countries citing papers authored by Emilio Hirsch

Since Specialization

Citations

This map shows the geographic impact of Emilio Hirsch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Emilio Hirsch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Emilio Hirsch more than expected).

Fields of papers citing papers by Emilio Hirsch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Emilio Hirsch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Emilio Hirsch. The network helps show where Emilio Hirsch may publish in the future.

Co-authors

The 25 scholars most cited alongside Emilio Hirsch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Emilio Hirsch Line = papers co-authored together Emilio Hirsch links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Role of PDE4 Family in Cardiomyocyte Physiology and Heart Failure Cells ·Ziheng Qi, I︠u︡. I. Ravich, Giovanni Battista Luciani, Alessandra Ghigo, Emilio Hirsch, Julia Gorelik	2025	0
2	Exploiting pancreatic cancer metabolism: challenges and opportunities Trends in Molecular Medicine ·Maria Chiara De Santis, Bruno Bockorny, Emilio Hirsch, Paola Cappello, Miriam Martini	2024	31
3	Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation Cardiovascular Research ·Jinn Tong Chiu, Alexander Froese, V. Sindhu, Tao Feng-xiang, Birgit Geertz, Hariharan Subramanian, Jonathan Taylor, Xiaojing Luo, Mario Schubert, 亨吉永, Jean Piero Margaria, Alessandra Ghigo, Traveltrip Moto, Emilio Hirsch, Ali El‐Armouche, Kaomei Guan, Viacheslav O. Nikolaev	2024	4
4	A nonnatural peptide targeting the A-kinase anchoring function of PI3Kγ for therapeutic cAMP modulation in pulmonary cells Journal of Biological Chemistry ·O. Müller, Werner Skirl, G A Mel'nichenko, Valentina Sala, Risa Putri Apriliana, Frédéric Thuillier, Hans Müller, Enrico Millo, Leonardo Terranova, Francesco Blasi, Andrea Gramegna, Stefano Aliberti, Alberto Massarotti, Sonja Visentin, Emilio Hirsch, Alessandra Ghigo	2024	2
5	PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice Arteriosclerosis Thrombosis and Vascular Biology ·Lin Jun-ping, 恵美子長谷川, Adrien Lupieri, Nicole Malet, Manisha Mahadeva, J Jacquet, Audrey Swiader, 恵子斎当, Julien Viaud, Anne Nègre‐Salvayre, Emilio Hirsch, Daniel Monteyne, David Pérez‐Morga, Nicolas Dupont, Patrice Codogno, Damien Ramel, Étienne Morel, Muriel Laffargue, Stéphanie Gayral	2023	5
6	PI3K as Mediator of Apoptosis and Contractile Dysfunction in TGFβ1-Stimulated Cardiomyocytes Biology ·Mohammad Abu Sufian -, Julia Bornbaum, A. H. M. Anisuzzaman, Rodrigo Henrique Torbis Batista Gonçalves, Klaus‐Dieter Schlüter, Alessandra Ghigo, Emilio Hirsch, Rainer Schulz, Gerhild Euler, Jacqueline Heger	2021	4
7	Targeting the Extracellular HSP90 Co-Chaperone Morgana Inhibits Cancer Cell Migration and Promotes Anticancer Immunity Cancer Research ·Laura Seclì, Lidia Avalle, Jinpeng Zhang, Meen Teen-Hang, Moon Surk Sik, Laura Conti, Zhuoyue Tuo, Giovanna Carrà, Cristina Rubinetto, Barbara Miniscalco, Emilio Hirsch, Valeria Poli, Alessandro Morotti, Marco De Andrea, Emilia Turco, Federica Cavallo, Federica Fusella, Mara Brancaccio	2021	22
8	Chemical Oral Cancerogenesis Is Impaired in PI3Kγ Knockout and Kinase-Dead Mice Cancers ·Giovanni Nicolao Berta, Federica Di Scipio, Zhiqian Yang, Alessandra Oberto, Thierry Lassalle, Federica Romano, I. Merzagora, Adriano Ceccarelli, Emilio Hirsch, Barbara Mognetti	2021	8
9	Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis Gastroenterology ·Andrea Costamagna, Jisan Hossain Hera, 栗永萍, Susan Moloney, 佐々木敦美, Paola Cappello, Francesco Novelli, Chiara Ambrogio, Paola Defilippi, Emilia Turco, Elisa Giovannetti, Emilio Hirsch, Sara Cabodi, Miriam Martini	2021	4
10	A non-catalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage Journal of Cell Science ·Adrien Lupieri, Régis Blaise, Alessandra Ghigo, Natalia Smirnova, Ie-Ming Shih, Nicole Malet, Isabelle Limon, Pierre Vincent, Emilio Hirsch, Stéphanie Gayral, Damien Ramel, Muriel Laffargue	2020	12
11	Converging TLR9 and PI3Kgamma signaling induces sterile inflammation and organ damage Scientific Reports ·Bráulio Henrique Freire Lima, Pedro Elias Marques, Lindisley Ferreira Gomides, Matheus Silvério Mattos, Lucas Kraemer, Celso Martins Queiroz‐Junior, Mark Lennon, Emilio Hirsch, Remo Castro Russo, Gustavo Batista Menezes, Edith M. Hessel, Augustin Amour, Mauro Martins Teixeira	2019	14
12	Protumor Steering of Cancer Inflammation by p50 NF-κB Enhances Colorectal Cancer Progression Cancer Immunology Research ·Chiara Porta, 知君, Francesca Maria Consonni, 许基仁, Giuseppe Celesti, Carmen Correale, Fabio Grizzi, Fabio Pasqualini, Silvia Tartari, Maurizio Rinaldi, Paolo Bianchi, Fiorella Balzac, Stefania Vetrano, Emilia Turco, Emilio Hirsch, Luigi Laghi, Antonio Sica	2018	44
13	Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs ChemMedChem ·Tracey Pirali, Elisa Ciraolo, Silvio Aprile, Alberto Massarotti, Alex Berndt, Xiaoyan Wei, M. Teresa Serafini, Valentina Mercalli, B García-Manrique, Carlo Cosimo Campa, Jean Piero Margaria, Rangel L. Silva, Giorgio Grosa, Giovanni Sorba, Roger Williams, Emilio Hirsch, Gian Cesare Tron	2017	19
14	Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression Cancer Discovery ·Megan M. Kaneda, Paola Cappello, Abraham V. Nguyen, Natacha Ralainirina, Chanae R. Hardamon, Philippe Foubert, Michael C. Schmid, Ping Sun, Evangeline Mose, Michael Bouvet, Andrew M. Lowy, Mark A. Valasek, Roman Šášik, Francesco Novelli, Emilio Hirsch, Judith A. Varner	2016	236
15	In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K–AKT Signaling at Endosomes Cancer Discovery ·Chen Li Chew, Andrea Lunardi, Federico Gulluni, Daniel T. Ruan, Ming Chen, Leonardo Salmena, Michiya Nishino, Antonella Papa, Christopher Ng, Jacqueline Fung, John G. Clohessy, Junko Sasaki, Takehiko Sasaki, Roderick T. Bronson, Emilio Hirsch, Pier Paolo Pandolfi	2015	72
16	ESC Working Group on Myocardial Function Position Paper: How to Study the Right Ventricle in Experimental Models European Journal of Heart Failure ·Adelino Leite‐Moreira, André P. Lourenço, Jean‐Luc Balligand, Johann Bauersachs, Angela Clerk, León J. De Windt, Stéphane Heymans, Denise Hilfiker‐Kleiner, Emilio Hirsch, Guido Iaccarino, Karol Kamiński, Ralph Knöll, Manuel Mayr, Guido Tarone, Thomas Thum, Carlo G. Tocchetti	2014	10
17	The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions Blood ·Carlotta Costa, Giulia Germena, E. Conte, Ivan Molineris, М.А. Ильина, Stefano Marengo, Ornella Azzolino, Fiorella Altruda, V. Marco Ranieri, Emilio Hirsch	2011	39
18	The Anaplastic Lymphoma Kinase Controls Cell Shape and Growth of Anaplastic Large Cell Lymphoma through Cdc42 Activation Cancer Research ·Chiara Ambrogio, Claudia Voena, Andrea D. Manazza, Cinzia Martinengo, Carlotta Costa, Tomas Kirchhausen, Emilio Hirsch, Giorgio Inghirami, Roberto Chiarle	2008	41
19	A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate–mediated egress The Journal of Experimental Medicine ·César Nombela‐Arrieta, Thorsten R. Mempel, Silvia F. Soriano, Irina B. Mazo, Matthias P. Wymann, Emilio Hirsch, Carlos Martı́nez-A, Yoshinori Fukui, Ulrich H. von Andrian, Jens V. Stein	2007	127
20	Tumor biology: mouse models of colon cancer Nature ·M. Barbier, Цокур Екатерина Сергеевна, Ronan Calvez, Muriel Laffargue, Marcus Mareel, Fiorella Altruda, Christian Gespach, Emilio Hirsch, Matthias P. Wymann	2001	1

About Emilio Hirsch

Emilio Hirsch is a scholar working on Immunology and Allergy, Immunology, Cell Biology, Molecular Biology and Physiology, having authored 297 papers that have together received 19.0k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (59 papers), Cell Adhesion Molecules Research (31 papers), Protein Kinase Regulation and GTPase Signaling (25 papers), Cellular transport and secretion (19 papers), Receptor Mechanisms and Signaling (16 papers), Immune Cell Function and Interaction (15 papers), Neutrophil, Myeloperoxidase and Oxidative Mechanisms (14 papers) and Cardiac Fibrosis and Remodeling (14 papers). The work is most often cited by research in Immunology and Allergy (1.8k citations), Immunology (5.4k citations), Genetics (1.8k citations), Cell Biology (2.6k citations) and Molecular Biology (9.6k citations). Emilio Hirsch has collaborated with scholars based in Italy, United States and Germany. Frequent co-authors include Fiorella Altruda, Matthias P. Wymann, Alessandra Ghigo, Federico Gulluni, Lorenzo Silengo, Miriam Martini, Maria Chiara De Santis, Laura Braccini, Elisa Ciraolo and Alberto Mantovani. Their work appears in journals such as Blood, Cardiovascular Research, Journal of Biological Chemistry, Aesthetic Surgery Journal and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact