Elena A. Lesnik

4.6k citations

46 papers · 3.7k indexed · 1 hit paper · h-index 24

Co-authors: Susan M. Freier P. Dan Cook Andrew M. Kawasaki Charles J. Guinosso Brett P. Monia Sandra Freier Henri Sasmor D. P. C. MCGEE
Topics: DNA and Nucleic Acid Chemistry (36 papers)RNA and protein synthesis mechanisms (27 papers)Advanced biosensing and bioanalysis techniques (18 papers)
Cited by: Molecular Biology Cancer Research Ecology
Journals: Proceedings of the National Academy of Sciences Journal of the American Chemical Society Nucleic Acids Research
Partner nations: United States Russia Slovakia

In The Last Decade

Elena A. Lesnik

45 papers receiving 3.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evaluation of 2‘-modified oligonucleotides containing 2‘-deoxy gaps as antisense inhibitors of gene expression

1993 626 citations Brett P. Monia, Elena A. Lesnik et al. profile →

Peers

Countries citing papers authored by Elena A. Lesnik

Since Specialization

Citations

This map shows the geographic impact of Elena A. Lesnik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elena A. Lesnik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elena A. Lesnik more than expected).

Fields of papers citing papers by Elena A. Lesnik

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elena A. Lesnik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elena A. Lesnik. The network helps show where Elena A. Lesnik may publish in the future.

Co-authorship network of co-authors of Elena A. Lesnik

This figure shows the co-authorship network connecting the top 25 collaborators of Elena A. Lesnik. A scholar is included among the top collaborators of Elena A. Lesnik based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Elena A. Lesnik. Elena A. Lesnik is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Identification of conserved regulatory RNA structures in prokaryotic metabolic pathway genes 2004 ·Biosystems ·Elena A. Lesnik,Gary B. Fogel,Dana Weekes,Timothy J. Henderson,Harold B. Levene,Rangarajan Sampath,David J. Ecker	14
2	Antisense phosphorothioate oligodeoxyribonucleotide targeted against ICAM-1: synthetic and biological characterization of a process-related impurity formed during oligonucleotide synthesis 2003 ·Bioorganic & Medicinal Chemistry ·Vasulinga T. Ravikumar,Daniel C. Capaldi,Walt F. Lima,Elena A. Lesnik,(unknown),Douglas L. Cole	6
3	Improving Antisense Oligonucleotide Binding to Human Serum Albumin: Dramatic Effect of Ibuprofen Conjugation 2002 ·ChemBioChem ·Muthiah Manoharan,Gopal B. Inamati,Elena A. Lesnik,Namir Sioufi,Susan M. Freier	9
4	A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome 2002 ·Biosystems ·Shawn Chen,Elena A. Lesnik,Thomas A. Hall,Rangarajan Sampath,Richard H. Griffey,David J. Ecker,Lawrence B. Blyn	176
5	Prediction of rho-independent transcriptional terminators in Escherichia coli 2001 ·Nucleic Acids Research ·Elena A. Lesnik	191
6	Pharmacokinetic Properties of 2′-O-(2-Methoxyethyl)-Modified Oligonucleotide Analogs in Rats 2001 ·Journal of Pharmacology and Experimental Therapeutics ·Richard S. Geary,Tanya Watanabe,L Truong,Sue Freier,Elena A. Lesnik,Namir Sioufi,Henri Sasmor,(unknown),Arthur A. Levin	236
7	Inhibition of Translation of Hepatitis C Virus RNA by 2′-Modified Antisense Oligonucleotides 1999 ·Antisense and Nucleic Acid Drug Development ·Vickie Brown‐Driver,(unknown),Elena A. Lesnik,Kevin Anderson,Ronnie Hanecak	32
8	Biophysical and antisense properties of oligodeoxynucleotides containing 7-propynyl-, 7-iodo- and 7-cyano-7-deaza-2-amino-2'-deoxyadenosines 1998 ·Nucleic Acids Research ·(unknown),V. Mohan,Elena A. Lesnik,(unknown),Brett P. Monia,(unknown)	32
9	Evaluation of pyrimidine PNA binding to ssDNA targets from nonequilibrium melting experiments 1997 ·Nucleic Acids Research ·Elena A. Lesnik	14
10	Synthesis and Incorporation of 2′-O-Methyl-Pseudouridine into Oligonucleotides 1997 ·Nucleosides and Nucleotides ·Bruce S. Ross,Guillermo Vasquez,(unknown),Elena A. Lesnik,Richard H. Griffey	2
11	Positioning of Functionalities in a Heteroduplex Major Groove: Synthesis of 7-Deaza-2-Amino-2′-deoxyadenosines 1997 ·Nucleosides and Nucleotides ·(unknown),(unknown),Elena A. Lesnik,Oscar L. Acevedo	1
12	2‘-O-Aminopropyl Ribonucleotides: A Zwitterionic Modification That Enhances the Exonuclease Resistance and Biological Activity of Antisense Oligonucleotides 1996 ·Journal of Medicinal Chemistry ·Richard H. Griffey,Brett P. Monia,(unknown),Susan M. Freier,Michael J. Greig,Charles J. Guinosso,Elena A. Lesnik,(unknown),V. Mohan,(unknown),(unknown),Henri Sasmor,(unknown),(unknown),(unknown),P. Dan Cook	115
13	Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity 1995 ·Nucleic Acids Research ·Lendell L. Cummins,Stephen R. Owens,Lisa M. Risen,Elena A. Lesnik,Sandra Freier,D. P. C. MCGEE,Charles J. Guinosso,P. Dan Cook	292
14	Relative Thermodynamic Stability of DNA, RNA, and DNA:RNA Hybrid Duplexes: Relationship with Base Composition and Structure 1995 ·Biochemistry ·Elena A. Lesnik,Susan M. Freier	235
15	Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes 1993 ·Biochemistry ·Elena A. Lesnik,Charles J. Guinosso,Andrew M. Kawasaki,Henri Sasmor,Maryann C. Zounes,Lendell L. Cummins,David J. Ecker,P. Dan Cook,Susan M. Freier	181
16	Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets 1993 ·Journal of Medicinal Chemistry ·Andrew M. Kawasaki,Martin D. Casper,Susan M. Freier,Elena A. Lesnik,Maryann C. Zounes,Lendell L. Cummins,Carolyn Gonzalez,P. Dan Cook	344
17	Tritium labeling of antisense oligonucleotides by exchange with tritiated water 1993 ·Nucleic Acids Research ·Mark J. Graham,Sandra Freier,Rosanne M. Crooke,David J. Ecker,(unknown),Elena A. Lesnik	53
18	The inhibition of restriction endonucleases due to Z‐DNA in negatively supercoiled plasmid 1991 ·FEBS Letters ·Elena A. Lesnik,(unknown),(unknown),(unknown)	3
19	Conformational Peculiarities of Polynucleotides with a Nonrandom Base Sequence According to the¹H→³H Exchange Rate in C8H Groups of Purinic Residues 1987 ·Journal of Biomolecular Structure and Dynamics ·Elena A. Lesnik,(unknown),Ilana Agranovich,Ya.M. Varshavsky	4
20	Influence of tertiary structure upon the rate of isotope hydrogen exchange in C₍₈₎H groups of tRNA purine residues 1973 ·FEBS Letters ·Elena A. Lesnik,(unknown),(unknown),Ya.M. Varshavsky	10

About Elena A. Lesnik

Elena A. Lesnik is a scholar working on Molecular Biology, Pharmaceutical Science and Industrial and Manufacturing Engineering, having authored 46 papers that have together received 3.7k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (36 papers), RNA and protein synthesis mechanisms (27 papers) and Advanced biosensing and bioanalysis techniques (18 papers). The work is most often cited by research in Molecular Biology (3.4k citations), Cancer Research (230 citations) and Ecology (326 citations). Elena A. Lesnik has collaborated with scholars based in United States, Russia and Slovakia. Frequent co-authors include Susan M. Freier, P. Dan Cook, Andrew M. Kawasaki, Charles J. Guinosso, Brett P. Monia, Sandra Freier, Henri Sasmor, D. P. C. MCGEE, Lendell L. Cummins and C. Gonzalez. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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