Daniel C. Capaldi

766 total citations
30 papers, 561 citations indexed

About

Daniel C. Capaldi is a scholar working on Molecular Biology, Organic Chemistry and Infectious Diseases. According to data from OpenAlex, Daniel C. Capaldi has authored 30 papers receiving a total of 561 indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 6 papers in Organic Chemistry and 5 papers in Infectious Diseases. Recurrent topics in Daniel C. Capaldi's work include DNA and Nucleic Acid Chemistry (25 papers), Advanced biosensing and bioanalysis techniques (19 papers) and RNA Interference and Gene Delivery (8 papers). Daniel C. Capaldi is often cited by papers focused on DNA and Nucleic Acid Chemistry (25 papers), Advanced biosensing and bioanalysis techniques (19 papers) and RNA Interference and Gene Delivery (8 papers). Daniel C. Capaldi collaborates with scholars based in United States, United Kingdom and Sweden. Daniel C. Capaldi's co-authors include Vasulinga T. Ravikumar, Douglas L. Cole, Hans Gaus, Colin B. Reese, Achim H. Krotz, Anthony N. Scozzari, Claus Rentel, James V. McArdle, Matthias Kretschmer and Cathaline den Besten and has published in prestigious journals such as Nucleic Acids Research, The Journal of Organic Chemistry and Bioorganic & Medicinal Chemistry.

In The Last Decade

Daniel C. Capaldi

30 papers receiving 533 citations

Peers

Daniel C. Capaldi

SPECT

Mate Rusz Austria

Dariusz J. Janecki United States

William Burkitt United Kingdom

U. Schweiger-Hufnagel Germany

Jiang-Hui Ding China

Kellye A. Cupp‐Sutton United States

Anissa W. Wong United States

Arnaud Delobel France

Edward J. Takach United States

Alexander Boychenko Germany

Mate Rusz Austria

Daniel C. Capaldi

179 ×0.4

75 ×0.5

SPECT

45 ×0.7

24 ×0.4

5 ×0.2

Citations per year, relative to Daniel C. Capaldi Daniel C. Capaldi (= 1×) peers Mate Rusz

Countries citing papers authored by Daniel C. Capaldi

Since Specialization

Citations

This map shows the geographic impact of Daniel C. Capaldi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniel C. Capaldi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniel C. Capaldi more than expected).

Fields of papers citing papers by Daniel C. Capaldi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel C. Capaldi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel C. Capaldi. The network helps show where Daniel C. Capaldi may publish in the future.

Co-authorship network of co-authors of Daniel C. Capaldi

This figure shows the co-authorship network connecting the top 25 collaborators of Daniel C. Capaldi. A scholar is included among the top collaborators of Daniel C. Capaldi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Daniel C. Capaldi. Daniel C. Capaldi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Rentel, Claus, et al.. (2022). Assay, Purity, and Impurity Profile of Phosphorothioate Oligonucleotide Therapeutics by Ion Pair–HPLC–MS. Nucleic Acid Therapeutics. 32(3). 206–220. 33 indexed citations

McPherson, A., Daniel C. Capaldi, Lijian Chen, & Philip Olsen. (2020). An Improved Process for the Manufacture of 5′-O-(4,4′-Dimethoxytrityl)-N²-isobutyryl-2′-O-(2-methoxyethyl)guanosine. Organic Process Research & Development. 24(11). 2583–2590. 4 indexed citations

Kim, Tae‐Won, et al.. (2019). Impurity Qualification Toxicology Study for a 2′-O-Methoxyethyl-Modified Antisense Inhibitor in Mice. Nucleic Acid Therapeutics. 30(1). 14–21. 1 indexed citations

Rentel, Claus, et al.. (2019). Determination of oligonucleotide deamination by high resolution mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 173. 56–61. 13 indexed citations

Roussis, Stilianos G., et al.. (2018). Rapid oligonucleotide drug impurity determination by direct spectral comparison of ion‐pair reversed‐phase high‐performance liquid chromatography electrospray ionization mass spectrometry data. Rapid Communications in Mass Spectrometry. 32(14). 1099–1106. 18 indexed citations

Capaldi, Daniel C., Scott P. Henry, Cathaline den Besten, et al.. (2017). Impurities in Oligonucleotide Drug Substances and Drug Products. Nucleic Acid Therapeutics. 27(6). 309–322. 95 indexed citations

Capaldi, Daniel C., Doug A. Brooks, Ken Draper, et al.. (2012). Quality Aspects of Oligonucleotide Drug Development: Specifications for Active Pharmaceutical Ingredients. Drug Information Journal. 46(5). 611–626. 23 indexed citations

Tedebark, Ulf, Anthony N. Scozzari, Oleg Werbitzky, Daniel C. Capaldi, & Lars Holmberg. (2010). Industrial-Scale Manufacturing of a Possible Oligonucleotide Cargo CPP-Based Drug. Methods in molecular biology. 683. 505–524. 9 indexed citations

Capaldi, Daniel C. & Anthony N. Scozzari. (2008). ChemInform Abstract: Manufacturing and Analytical Processes for 2′‐O‐(2‐Methoxyethyl)‐modified Oligonucleotides. ChemInform. 39(38). 1 indexed citations

10.

Gaus, Hans, et al.. (2005). Characterization of high molecular weight impurities in synthetic phosphorothioate oligonucleotides. Bioorganic & Medicinal Chemistry Letters. 16(3). 607–614. 20 indexed citations

11.

Gaus, Hans, et al.. (2005). Trichloroacetaldehyde modified oligonucleotides. Bioorganic & Medicinal Chemistry Letters. 15(18). 4118–4124. 21 indexed citations

12.

Capaldi, Daniel C., Hans Gaus, James V. McArdle, et al.. (2004). Formation of 4,4′-dimethoxytrityl-C-phosphonate oligonucleotides. Bioorganic & Medicinal Chemistry Letters. 14(18). 4683–4690. 25 indexed citations

13.

Ravikumar, Vasulinga T., R. Kumar, Daniel C. Capaldi, & Douglas L. Cole. (2003). Synthesis of High Quality Phosphorothioate Oligonucleotides as Antisense Drugs. Use of I-Linker in the Elimination of 3′-Terminal Phosphorothioate Monoesters. Nucleosides Nucleotides & Nucleic Acids. 22(5-8). 1421–1425. 7 indexed citations

14.

Ravikumar, Vasulinga T., et al.. (2003). Antisense Phosphorothioate Oligodeoxyribonucleotide Targeted against ICAM-1: Use of I-Linker to Eliminate 3‘-Terminal Phosphorothioate Monoester Formation. Organic Process Research & Development. 7(3). 259–266. 14 indexed citations

15.

Ravikumar, Vasulinga T., et al.. (2003). Antisense phosphorothioate oligodeoxyribonucleotide targeted against ICAM-1: synthetic and biological characterization of a process-related impurity formed during oligonucleotide synthesis. Bioorganic & Medicinal Chemistry. 11(21). 4673–4679. 6 indexed citations

16.

Capaldi, Daniel C., Douglas L. Cole, & Vilwanathan Ravikumar. (2000). Highly efficient solid phase synthesis of oligonucleotide analogs containing phosphorodithioate linkages. Nucleic Acids Research. 28(9). e40–e40. 4 indexed citations

17.

Cheruvallath, Zacharia S., Daniel C. Capaldi, Achim H. Krotz, et al.. (1999). Synthesis of Antisense Oligonucleotides: Replacement of 3H-1,2-Benzodithiol-3-one 1,1-Dioxide (Beaucage Reagent) with Phenylacetyl Disulfide (PADS) As Efficient Sulfurization Reagent: From Bench to Bulk Manufacture of Active Pharmaceutical Ingredient. Organic Process Research & Development. 4(3). 199–204. 43 indexed citations

18.

Cheruvallath, Zacharia S., et al.. (1999). Oligodeoxyribonucleotide Phosphorothioates: Substantial Reduction of (N-1)-Mer Content Through the Use of Blockmer Phosphoramidite Synthons. Nucleosides and Nucleotides. 18(6-7). 1211–1213. 1 indexed citations

19.

Cheruvallath, Zacharia S., et al.. (1999). Synthesis of Dimer Phosphoramidite Synthons for Oligodeoxyribonucleotide Phosphorothioates Using Diethyldithiocarbonate disulfide as an Efficient Sulfurizing Reagent. Nucleosides and Nucleotides. 18(8). 1803–1807. 14 indexed citations

20.

Capaldi, Daniel C. & Colin B. Reese. (1994). Use of the 1-(2-fluorophenyl)-4-methoxypiperidin-4-yl (Fpmp) and related protecting groups in oligoribonucleotide synthesis: stability of internucleotide linkages to aqueous acid. Nucleic Acids Research. 22(12). 2209–2216. 43 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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