P. Andrew Karplus

26.8k citations

196 papers · 21.8k indexed · 9 hit papers · h-index 75

Impact in

Biochemistry top 0.05%
- Sulfur Compounds in Biology
Molecular Biology top 0.1%
- Redox biology and oxidative stress
- Protein Structure and Dynamics
- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- Glutathione Transferases and Polymorphisms

Papers in

Biochemistry 27
- Sulfur Compounds in Biology 16
Molecular Biology 150
- Protein Structure and Dynamics 41
- Redox biology and oxidative stress 41
- RNA and protein synthesis mechanisms 15
- Photosynthetic Processes and Mechanisms 13

Co-authors: Leslie B. Poole Georg E. Schulz Kay Diederichs Zachary A. Wood Robert P. Hausinger Jon Clardy Robert F. Standaert Stuart L. Schreiber
Journals: Biochemistry (31 papers)Journal of Molecular Biology (23 papers)Protein Science (19 papers)Journal of Biological Chemistry (15 papers)Science (7 papers)
Partner nations: United States Germany Italy

In The Last Decade

P. Andrew Karplus

194 papers receiving 21.4k citations

Hit Papers

9 papers align trajectories log scale

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling 2015 · 472 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 Trends in Biochemical Sciences
2012 Science
2003 Science
1997 Nature Structural Biology
1995 Science
1993 Journal of Molecular Biology
1991 Science
1987 Journal of Molecular Biology
1985 Die Naturwissenschaften

Peers

Countries citing papers authored by P. Andrew Karplus

Since Specialization

Citations

This map shows the geographic impact of P. Andrew Karplus's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by P. Andrew Karplus with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites P. Andrew Karplus more than expected).

Fields of papers citing papers by P. Andrew Karplus

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by P. Andrew Karplus. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by P. Andrew Karplus. The network helps show where P. Andrew Karplus may publish in the future.

Co-authors

The 25 scholars most cited alongside P. Andrew Karplus, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with P. Andrew Karplus Line = papers co-authored together P. Andrew Karplus links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	In-Cell Approach to Evaluate E3 Ligases for Use in Targeted Protein Degradation Journal of the American Chemical Society ·Yunan Zheng, Anamika Singh, Olga Calcagnile, Violeta L. Marin, Jennifer A. Young, Paul L. Richardson, Natalia Ratna Mudita, Richard B. Cooley, P. Andrew Karplus, Kedar Puvar, Scott E. Warder, Anil Vasudevan, Justin M. Reitsma, Ryan A. Mehl	2025	2
2	Truncation-Free Genetic Code Expansion with Tetrazine Amino Acids for Quantitative Protein Ligations Bioconjugate Chemistry ·S Sztarkman, Cíntia Débora de Moraes Cinti, Subhashis Jana, И. В. Маланьин, SC Solid, Kyle Meyer, John J. Perona, Richard B. Cooley, P. Andrew Karplus, Ryan A. Mehl	2023	11
3	Nanobody assemblies with fully flexible topology enabled by genetically encoded tetrazine amino acids Science Advances ·Muh. Khamdan, Cíntia Débora de Moraes Cinti, Subhashis Jana, 一貴中村, Joseph S. Beckman, P. Andrew Karplus, Ryan A. Mehl	2022	15
4	Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2 Journal of Biological Chemistry ·Alexander V. Peskin, Flávia Carla Meotti, K.M. Kean, Christoph Göbl, Laise Kelma Costa Magalhães, Paul Pace, Christopher R. Horne, Hitoshi TAKAHASH, B. Hoxhold, Renwick C. J. Dobson, P. Andrew Karplus, Christine C. Winterbourn	2021	15
5	Immobilization of Proteins with Controlled Load and Orientation ACS Applied Materials & Interfaces ·Cíntia Débora de Moraes Cinti, Thaddeus W. Golbek, K.M. Kean, Karla Denisse Morales Gutierrez, Subhashis Jana, Joe E. Baio, P. Andrew Karplus, Ryan A. Mehl	2019	41
6	Substrate Specificity in Thiol Dioxygenases Biochemistry ·Carmen Pace, Casey G. Davies, P. Andrew Karplus, Sigurd M. Wilbanks, Guy N. L. Jameson	2019	30
7	High‐resolution studies of hydride transfer in the ferredoxin:NADP⁺ reductase superfamily FEBS Journal ·K.M. Kean, R. Rebolo, V. Pandini, Giuliana Zanetti, Andrea Hall, Ubong Ekerete Josiah, Alessandro Aliverti, P. Andrew Karplus	2017	22
8	The sedoheptulose 7-phosphate cyclases and their emerging roles in biology and ecology Natural Product Reports ·Adam Bourne, K.M. Kean, P. Andrew Karplus, Taifo Mahmud	2017	13
9	Evolution and Distribution of C₇–Cyclitol Synthases in Prokaryotes and Eukaryotes ACS Chemical Biology ·Adam Bourne, K.M. Kean, Bibiana Rogel, Е. А. Черепанов, Shumpei Asamizu, D. Beduhn, P. Andrew Karplus, Taifo Mahmud	2017	19
10	De novo synthesis of a sunscreen compound in vertebrates eLife ·Adam Bourne, Е. А. Черепанов, In-suk Lee, Shumpei Asamizu, Jane LaDu, K.M. Kean, P. Andrew Karplus, Robert L. Tanguay, Alan T. Bakalinsky, Taifo Mahmud	2015	68
11	Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling Trends in Biochemical Sciences ·Arden Perkins, Kimberly Nelson, Derek Parsonage, Leslie B. Poole, P. Andrew Karplus Hit paper breakdown →	2015	472
12	Linking Crystallographic Model and Data Quality Science ·P. Andrew Karplus, Kay Diederichs Hit paper breakdown →	2012	1427
13	Iron-containing urease in a pathogenic bacterium Proceedings of the National Academy of Sciences ·Eric L. Carter, Dale E. Tronrud, W. Thornton Parker, P. Andrew Karplus, Robert P. Hausinger	2011	57
14	Cysteine-Based Redox Switches in Enzymes Antioxidants and Redox Signaling ·Chananat Klomsiri, P. Andrew Karplus, Leslie B. Poole	2010	297
15	A Putative Fe ²⁺ -Bound Persulfenate Intermediate in Cysteine Dioxygenase Biochemistry ·C.R. Simmons, Füsun Canpolat, Carol L. Thornton, David J. Schuller, John E. Dominy, Tadhg P. Begley, Martha H. Stipanuk, P. Andrew Karplus	2008	74
16	Site-Directed Mutagenesis Improves Catalytic Efficiency and Thermostability of Escherichia coli pH 2.5 Acid Phosphatase/Phytase Expressed in Pichia pastoris Archives of Biochemistry and Biophysics ·E. González Rodríguez, Zachary A. Wood, P. Andrew Karplus, Xin Gen Lei	2000	92
17	Characterization of metal-substituted Klebsiella aerogenes urease JBIC Journal of Biological Inorganic Chemistry ·Kenji Yamaguchi, Nathaniel J. Cosper, BARTHOD, Robert A. Scott, M.A. Pearson, P. Andrew Karplus, Robert P. Hausinger	1999	29
18	Structure-function relations for ferredoxin reductase Journal of Bioenergetics and Biomembranes ·P. Andrew Karplus, Christopher M. Bruns	1994	88
19	A crystallographic study of the glutathione binding site of glutathione reductase at 0.3‐nm resolution European Journal of Biochemistry ·P. Andrew Karplus, E.F. Pai, Georg E. Schulz	1989	143
20	Refined structure of glutathione reductase at 1.54 Å resolution Journal of Molecular Biology ·P. Andrew Karplus, Georg E. Schulz Hit paper breakdown →	1987	448

About P. Andrew Karplus

P. Andrew Karplus is a scholar working on Biochemistry, Molecular Biology, Inorganic Chemistry, Materials Chemistry and Cell Biology, having authored 196 papers that have together received 21.8k indexed citations. Recurring topics across this work include Enzyme Structure and Function (62 papers), Protein Structure and Dynamics (41 papers), Redox biology and oxidative stress (41 papers), Metal-Catalyzed Oxygenation Mechanisms (23 papers), Sulfur Compounds in Biology (16 papers), RNA and protein synthesis mechanisms (15 papers), Photosynthetic Processes and Mechanisms (13 papers) and Microbial Applications in Construction Materials (11 papers). The work is most often cited by research in Biochemistry (2.1k citations), Molecular Biology (15.3k citations), Biotechnology (1.1k citations), Inorganic Chemistry (1.7k citations) and Cell Biology (1.8k citations). P. Andrew Karplus has collaborated with scholars based in United States, Germany and Italy. Frequent co-authors include Leslie B. Poole, Georg E. Schulz, Kay Diederichs, Zachary A. Wood, Robert P. Hausinger, Kay Diederichs, Jon Clardy, Robert F. Standaert, Stuart L. Schreiber and Gregory D. Van Duyne. Their work appears in journals such as Biochemistry, Journal of Molecular Biology, Protein Science, Journal of Biological Chemistry and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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