C. Erik Hack

9.2k total citations · 2 hit papers
131 papers, 7.0k citations indexed

About

C. Erik Hack is a scholar working on Immunology, Hematology and Genetics. According to data from OpenAlex, C. Erik Hack has authored 131 papers receiving a total of 7.0k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Immunology, 42 papers in Hematology and 33 papers in Genetics. Recurrent topics in C. Erik Hack's work include Coagulation, Bradykinin, Polyphosphates, and Angioedema (30 papers), Blood Coagulation and Thrombosis Mechanisms (25 papers) and Complement system in diseases (15 papers). C. Erik Hack is often cited by papers focused on Coagulation, Bradykinin, Polyphosphates, and Angioedema (30 papers), Blood Coagulation and Thrombosis Mechanisms (25 papers) and Complement system in diseases (15 papers). C. Erik Hack collaborates with scholars based in Netherlands, United States and Germany. C. Erik Hack's co-authors include Sacha Zeerleder, Walter A. Wuillemin, L. Eijsman, Gertjan Wolbink, Rienk Nieuwland, Wim K. Lagrand, Cees A. Visser, Hans W.M. Niessen, Freek W.A. Verheugt and Hugo Ten Cate and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of Biological Chemistry.

In The Last Decade

C. Erik Hack

128 papers receiving 6.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

C-Reactive Protein as a Cardiovascular Risk Factor

1999 693 citations Gertjan Wolbink, C. Erik Hack et al. profile →
Activation of the Complement System During and After Cardiopulmonary Bypass Surgery

1997 637 citations Charles R.H. Wildevuur, L. Eijsman et al. profile →

Peers

Countries citing papers authored by C. Erik Hack

Since Specialization

Citations

This map shows the geographic impact of C. Erik Hack's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Erik Hack with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Erik Hack more than expected).

Fields of papers citing papers by C. Erik Hack

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Erik Hack. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Erik Hack. The network helps show where C. Erik Hack may publish in the future.

Co-authorship network of co-authors of C. Erik Hack

This figure shows the co-authorship network connecting the top 25 collaborators of C. Erik Hack. A scholar is included among the top collaborators of C. Erik Hack based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C. Erik Hack. C. Erik Hack is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Randomized phase I trial outcomes show safe and sustainable inhibition of classical and lectin complement pathways by empasiprubart 2025 ·Nature Communications ·Inge Van de Walle, (unknown), (unknown), (unknown), (unknown), P. Decker, (unknown), (unknown), Emma K. Persson, (unknown), Xing-Hong Leng, G.R. Andersen, Domenica Gandini, C. Erik Hack	0
2	Complement activation by IgM autoantibodies linked to immune‐mediated neuropathies depends on C2 2024 ·European Journal of Neurology ·(unknown), (unknown), (unknown), (unknown), W. Ludo van der Pol, Nicolette C. Notermans, Monique C. Minnema, Jeanette H.W. Leusen, C. Erik Hack, Inge Van de Walle	0
3	Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complement 2021 ·Journal of Controlled Release ·Mariona Estapé Sentí, (unknown), (unknown), J. Verhoef, János Szebeni, Gert Storm, C. Erik Hack, Raymond M. Schiffelers, Marcel H.A.M. Fens, Péter Boross	124
4	A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation 2019 ·Journal of Biological Chemistry ·Zonne L. M. Hofman, (unknown), (unknown), (unknown), (unknown), (unknown), Karoline Krause, (unknown), Jörg Scheffel, C. Erik Hack, Marcus Maurer, Steven de Maat, Coen Maas	19
5	Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle 2019 ·SHILAP Revista de lepidopterología ·(unknown), (unknown), (unknown), Stefan Nierkens, C. Erik Hack, Alwin D. R. Huitema, Erik M. van Maarseveen	10
6	Six-step workflow for the quantification of therapeutic monoclonal antibodies in biological matrices with liquid chromatography mass spectrometry – A tutorial 2019 ·Analytica Chimica Acta ·(unknown), (unknown), C. Erik Hack, Alwin D. R. Huitema, Erik M. van Maarseveen	19
7	Antibodies against Apoptotic Cells Present in End-stage Lung Disease Patients Do Not Correlate with Clinical Outcome after Lung Transplantation 2017 ·Frontiers in Immunology ·(unknown), E.A. van de Graaf, (unknown), (unknown), Johanna M. Kwakkel‐van Erp, C. Erik Hack, Henny G. Otten	3
8	Hereditary Angioedema Attacks: Local Swelling at Multiple Sites 2014 ·Clinical Reviews in Allergy & Immunology ·Zonne L. M. Hofman, Anurag Relan, C. Erik Hack	22
9	Inhibition of the Classical and Lectin Pathway of the Complement System by Recombinant LAIR-2 2013 ·Journal of Innate Immunity ·(unknown), Péter Boross, (unknown), J.H. Marco Jansen, Jeanette H.W. Leusen, Diana Wouters, Rolf T. Urbanus, C. Erik Hack, Linde Meyaard	20
10	Recombinant C1-Inhibitor 2011 ·BioDrugs ·Anurag Relan, Kamran Bakhtiari, Edwin S. van Amersfoort, Joost C.M. Meijers, C. Erik Hack	29
11	Intravenous Immunoglobulin (IVIG) Treatment for Modulation of Immune Activation in Human Immunodeficiency Virus Type 1 Infected Therapy-Naive Individuals 2007 ·AIDS Research and Human Retroviruses ·(unknown), Jan M. Prins, Evelien M. Bunnik, C. Erik Hack, Suzanne Jurriaans, Frank Miedema, Joep M. A. Lange, Hanneke Schuitemaker	8
12	Increased PAI-1 plasma levels and risk of death from dengue: no association with the 4G/5G promoter polymorphism 2005 ·Thrombosis Journal ·(unknown), (unknown), Penelope Koraka, C. Erik Hack, Anja Leyte, (unknown), Hugo Ten Cate, (unknown), (unknown), (unknown), (unknown)	23
13	The Impact of Heparin Coated Circuits Upon Metabolism in Vital Organs: Effect Upon Cerebral and Renal Function During and After Cardiopulmonary Bypass 2005 ·ASAIO Journal ·Roel de Vroege, Wim Stooker, Wim van Oeveren, (unknown), (unknown), Jan van Klarenbosch, Gerard J. van Kamp, C. Erik Hack, L. Eijsman, Charles R.H. Wildevuur	6
14	The Impact of Heparin-Coated Cardiopulmonary Bypass Circuits on Pulmonary Function and the Release of Inflammatory Mediators 2004 ·Anesthesia & Analgesia ·Roel de Vroege, Wim van Oeveren, Jan van Klarenbosch, Wim Stooker, M. A. J. M. Huybregts, C. Erik Hack, (unknown), L. Eijsman, Charles R.H. Wildevuur	45
15	Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner 2003 ·Journal of Thrombosis and Haemostasis ·Éva Bíró, (unknown), G.M.T. Vogel, D.G. Meuleman, Martine J. Smit, C. Erik Hack, Auguste Sturk, Rienk Nieuwland	248
16	Pro- and non-coagulant forms of non-cell-bound tissue factor in vivo 2003 ·Journal of Thrombosis and Haemostasis ·(unknown), Rienk Nieuwland, Fred P.H.T.M. Romijn, L. Eijsman, C. Erik Hack, Augueste Sturk	49
17	IC14, an Anti-CD14 Antibody, Inhibits Endotoxin-Mediated Symptoms and Inflammatory Responses in Humans 2001 ·The Journal of Immunology ·Annelies Verbon, Pascale E. P. Dekkers, Tessa ten Hove, C. Erik Hack, John P. Pribble, Terence Turner, Sonia Souza, Tim Axtelle, Frans J. Hoek, Sander J. H. van Deventer, Tom van der Poll	102
18	Therapy with interleukin-2 induces the systemic release of phospholipase-A2 1995 ·Cancer Immunology Immunotherapy ·Gertjan Wolbink, Caspar Schalkwijk, Joke W. Baars, John Wagstaff, H. van den Bosch, C. Erik Hack	38
19	Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees. 1994 ·Journal of Clinical Investigation ·Marcel Levi, Hugo Ten Cate, KA Bauer, Tom van der Poll, Thomas S. Edgington, Harry R. Büller, S J van Deventer, C. Erik Hack, J W ten Cate, R D Rosenberg	317
20	The Structure and Expression of the Genes for T-Kininogen in the Rat 1992 ·Birkhäuser Basel eBooks ·(unknown), C. Erik Hack	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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