C. Erik Hack

9.2k total citations · 2 hit papers
131 papers, 7.0k citations indexed

About

C. Erik Hack is a scholar working on Immunology, Hematology and Genetics. According to data from OpenAlex, C. Erik Hack has authored 131 papers receiving a total of 7.0k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Immunology, 42 papers in Hematology and 33 papers in Genetics. Recurrent topics in C. Erik Hack's work include Coagulation, Bradykinin, Polyphosphates, and Angioedema (30 papers), Blood Coagulation and Thrombosis Mechanisms (25 papers) and Complement system in diseases (15 papers). C. Erik Hack is often cited by papers focused on Coagulation, Bradykinin, Polyphosphates, and Angioedema (30 papers), Blood Coagulation and Thrombosis Mechanisms (25 papers) and Complement system in diseases (15 papers). C. Erik Hack collaborates with scholars based in Netherlands, United States and Germany. C. Erik Hack's co-authors include Sacha Zeerleder, Walter A. Wuillemin, L. Eijsman, Gertjan Wolbink, Rienk Nieuwland, Wim K. Lagrand, Cees A. Visser, Hans W.M. Niessen, Freek W.A. Verheugt and Hugo Ten Cate and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of Biological Chemistry.

In The Last Decade

C. Erik Hack

128 papers receiving 6.7k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

C-Reactive Protein as a Cardiovascular Risk Factor

1999 693 citations Gertjan Wolbink, C. Erik Hack et al. profile →
Activation of the Complement System During and After Cardiopulmonary Bypass Surgery

1997 637 citations L. Eijsman, C. Erik Hack et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
C. Erik Hack	1.8k	1.8k	1.5k	1.2k	1.1k	131	7.0k
C. Erik Hack	2.8k 1.5×	1.5k 0.9×	1.7k 1.1×	1.9k 1.5×	539 0.5×	93	7.6k
Elliot S. Barnathan	1.2k 0.7×	1.3k 0.7×	935 0.6×	1.4k 1.2×	562 0.5×	106	8.0k
James S. O’Donnell	1.1k 0.6×	3.8k 2.2×	661 0.4×	813 0.7×	957 0.8×	226	7.4k
Kenneth A. Ault	2.5k 1.4×	2.0k 1.2×	474 0.3×	1.1k 0.9×	788 0.7×	102	7.3k
H. Lévesque	741 0.4×	1.7k 1.0×	1.6k 1.1×	748 0.6×	822 0.7×	295	7.0k
Beate E. Kehrel	882 0.5×	2.4k 1.4×	606 0.4×	1.5k 1.2×	337 0.3×	120	6.3k
Augueste Sturk	2.1k 1.2×	2.4k 1.4×	839 0.6×	4.4k 3.6×	510 0.5×	120	10.0k
T Schaible	2.5k 1.4×	1.4k 0.8×	4.0k 2.7×	820 0.7×	565 0.5×	75	10.5k
John W. Semple	1.9k 1.0×	4.4k 2.5×	546 0.4×	862 0.7×	698 0.6×	171	7.4k
Wassim Y. Almawi	1.6k 0.9×	991 0.6×	1.0k 0.7×	1.1k 0.9×	333 0.3×	305	6.3k

Countries citing papers authored by C. Erik Hack

Since Specialization

Citations

This map shows the geographic impact of C. Erik Hack's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by C. Erik Hack with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites C. Erik Hack more than expected).

Fields of papers citing papers by C. Erik Hack

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by C. Erik Hack. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by C. Erik Hack. The network helps show where C. Erik Hack may publish in the future.

Co-authorship network of co-authors of C. Erik Hack

This figure shows the co-authorship network connecting the top 25 collaborators of C. Erik Hack. A scholar is included among the top collaborators of C. Erik Hack based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with C. Erik Hack. C. Erik Hack is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Walle, Inge Van de, P. Decker, Emma K. Persson, et al.. (2025). Randomized phase I trial outcomes show safe and sustainable inhibition of classical and lectin complement pathways by empasiprubart. Nature Communications. 16(1). 7639–7639.

Pol, W. Ludo van der, Nicolette C. Notermans, Monique C. Minnema, et al.. (2024). Complement activation by IgM autoantibodies linked to immune‐mediated neuropathies depends on C2. European Journal of Neurology. 32(1). e16541–e16541.

Hofman, Zonne L. M., Karoline Krause, Jörg Scheffel, et al.. (2019). A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation. Journal of Biological Chemistry. 295(2). 363–374. 19 indexed citations

Setten, Jessica van, et al.. (2019). The Autoimmune-Associated Single Nucleotide Polymorphism Within PTPN22 Correlates With Clinical Outcome After Lung Transplantation. Frontiers in Immunology. 9. 3105–3105. 4 indexed citations

Hofman, Zonne L. M., et al.. (2019). High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema. Clinical and Translational Allergy. 9(1). 35–35. 10 indexed citations

Nierkens, Stefan, et al.. (2019). Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle. SHILAP Revista de lepidopterología. 1. 100004–100004. 10 indexed citations

Visser, Harry, et al.. (2018). IL4-10 fusion protein as a disease modifying therapy for osteoarthritis evaluated in a rat groove model in vivo. Osteoarthritis and Cartilage. 26. S292–S292. 1 indexed citations

Graaf, E.A. van de, et al.. (2017). Antibodies against Apoptotic Cells Present in End-stage Lung Disease Patients Do Not Correlate with Clinical Outcome after Lung Transplantation. Frontiers in Immunology. 8. 322–322. 3 indexed citations

Fermie, Job, et al.. (2014). Granzyme K synergistically potentiates LPS-induced cytokine responses in human monocytes. Proceedings of the National Academy of Sciences. 111(16). 5974–5979. 56 indexed citations

10.

Graaf, E.A. van de, et al.. (2014). Anti-ETAR and anti-AT1R autoantibodies are elevated in patients with endstage cystic fibrosis. Journal of Cystic Fibrosis. 14(1). 42–45. 24 indexed citations

11.

Relan, Anurag, André C. Knulst, Dumitru Moldovan, et al.. (2012). Clinical Impact of Peripheral Attacks in Hereditary Angioedema Patients. The American Journal of Medicine. 125(9). 937.e17–937.e24. 19 indexed citations

12.

Prins, Jan M., Evelien M. Bunnik, C. Erik Hack, et al.. (2007). Intravenous Immunoglobulin (IVIG) Treatment for Modulation of Immune Activation in Human Immunodeficiency Virus Type 1 Infected Therapy-Naive Individuals. AIDS Research and Human Retroviruses. 23(11). 1348–1353. 8 indexed citations

13.

Koraka, Penelope, et al.. (2005). Increased PAI-1 plasma levels and risk of death from dengue: no association with the 4G/5G promoter polymorphism. Thrombosis Journal. 3(1). 17–17. 23 indexed citations

14.

Nieuwland, Rienk, et al.. (2003). Pro- and non-coagulant forms of non-cell-bound tissue factor in vivo. Journal of Thrombosis and Haemostasis. 1(9). 1920–1926. 49 indexed citations

15.

Verbon, Annelies, Pascale E. P. Dekkers, Tessa ten Hove, et al.. (2001). IC14, an Anti-CD14 Antibody, Inhibits Endotoxin-Mediated Symptoms and Inflammatory Responses in Humans. The Journal of Immunology. 166(5). 3599–3605. 102 indexed citations

16.

Hack, C. Erik. (2001). Fibrinolysis in Disseminated Intravascular Coagulation. Seminars in Thrombosis and Hemostasis. 27(6). 633–638. 42 indexed citations

17.

Marta, Rosana F., et al.. (1999). Proinflammatory cytokines and elastase-alpha-1-antitrypsin in Argentine hemorrhagic fever.. American Journal of Tropical Medicine and Hygiene. 60(1). 85–89. 54 indexed citations

18.

Wolbink, Gertjan, Caspar Schalkwijk, Joke W. Baars, et al.. (1995). Therapy with interleukin-2 induces the systemic release of phospholipase-A2. Cancer Immunology Immunotherapy. 41(5). 287–292. 38 indexed citations

19.

Levi, Marcel, Hugo Ten Cate, KA Bauer, et al.. (1994). Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.. Journal of Clinical Investigation. 93(1). 114–120. 317 indexed citations

20.

Hack, C. Erik, et al.. (1992). The Structure and Expression of the Genes for T-Kininogen in the Rat. Birkhäuser Basel eBooks. 38 ( Pt 1). 292–299. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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