A F Purchio

9.6k citations

85 papers · 8.4k indexed · 5 hit papers · h-index 48

Molecular Biology top 1%
Genetics top 1%
Oncology top 2%
Cancer Research top 2%
Immunology top 5%

Co-authors: Marc S. Collett L E Gentry R L Erikson E Erikson Hans Marquardt Raymond L. Erikson Mario N. Lioubin Harold L. Moses
Topics: Viral Infectious Diseases and Gene Expression in Insects (20 papers)Virus-based gene therapy research (19 papers)TGF-β signaling in diseases (11 papers)
Cited by: Immunology and Allergy Molecular Biology Cancer Research
Journals: Nature Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Austria Germany

In The Last Decade

A F Purchio

84 papers receiving 7.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin.

1990 647 citations L E Gentry, A F Purchio et al. profile →
Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

1992 604 citations F Oberhammer, A F Purchio et al. profile →
Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1980 450 citations Marc S. Collett, A F Purchio et al. profile →
Molecular cloning and nucleotide sequence of the pestivirus bovine viral diarrhea virus

1988 435 citations A F Purchio et al. profile →
Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 320 citations A F Purchio et al. profile →

Peers

Countries citing papers authored by A F Purchio

Since Specialization

Citations

This map shows the geographic impact of A F Purchio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A F Purchio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A F Purchio more than expected).

Fields of papers citing papers by A F Purchio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A F Purchio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A F Purchio. The network helps show where A F Purchio may publish in the future.

Co-authorship network of co-authors of A F Purchio

This figure shows the co-authorship network connecting the top 25 collaborators of A F Purchio. A scholar is included among the top collaborators of A F Purchio based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A F Purchio. A F Purchio is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Serum Amyloid A-Luciferase Transgenic Mice: Response to Sepsis, Acute Arthritis, and Contact Hypersensitivity and the Effects of Proteasome Inhibition 2005 ·The Journal of Immunology ·Ning Zhang,Muhammad Ahsan,A F Purchio,David B. West	72
2	In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs 2005 ·International Journal for Parasitology ·Stephen J. Davies,Steven J. Smith,K. C. Lim,Hongbing Zhang,A F Purchio,James H. McKerrow,David B. West	21
3	Non-invasive imaging of GFAP expression after neuronal damage in mice 2004 ·Neuroscience Letters ·Lingyun Zhu,Sylvie Ramboz,(unknown),Landin Boring,David Grass,A F Purchio	85
4	An Inducible Nitric Oxide Synthase-Luciferase Reporter System for In Vivo Testing of Anti-inflammatory Compounds in Transgenic Mice 2003 ·The Journal of Immunology ·Ning Zhang,(unknown),(unknown),(unknown),Pamela R. Contag,A F Purchio,David B. West	59
5	A TRANSGENIC MOUSE MODEL WITH A LUCIFERASE REPORTER FOR STUDYING IN VIVO TRANSCRIPTIONAL REGULATION OF THE HUMAN CYP3A4 GENE 2003 ·Drug Metabolism and Disposition ·Weisheng Zhang,A F Purchio,Kevin Chen,Jianming Wu,Lu Li,(unknown),Pamela R. Contag,David B. West	54
6	βIG-H3, a Novel Secretory Protein Inducible by Transforming Growth Factor-β, Is Present in Normal Skin and Promotes the Adhesion and Spreading of Dermal Fibroblasts In Vitro 1995 ·Journal of Investigative Dermatology ·Richard G. LeBaron,(unknown),Michael Zimber,(unknown),John E. Skonier,A F Purchio	194
7	Cartilage production by rabbit articular chondrocytes on polyglycolic acid scaffolds in a closed bioreactor system 1995 ·Biotechnology and Bioengineering ·(unknown),Michael Zimber,Richard G. LeBaron,(unknown),Michael Kwan,A F Purchio	116
8	Nonenzymatic glycosylation of poly-l-lysine: A new tool for targeted gene delivery 1994 ·Hepatology ·Daniel Martínez‐Fong,Jerald E. Mullersman,A F Purchio,Juan Armendáriz‐Borunda,Antonio Martinez-Hernandez	51
9	βig-h3: A Transforming Growth Factor-β-Responsive Gene Encoding a Secreted Protein That Inhibits Cell Attachment In Vitro and Suppresses the Growth of CHO Cells in Nude Mice 1994 ·DNA and Cell Biology ·John E. Skonier,Kelly L. Bennett,Victoria Rothwell,(unknown),Gregory D. Plowman,P. Wallace,Susanne Edelhoff,Christine M. Distèche,(unknown),Hans Marquardt,(unknown),A F Purchio	245
10	Transforming growth factor-β 1 as a signal for induction of cell death by apoptosis 1993 ·British Journal of Cancer ·Wilfried Bursch,F Oberhammer,Randy L. Jirtle,(unknown),Roland Sedivy,Bettina Grasl‐Kraupp,A F Purchio,Rolf Schulte‐Hermann	145
11	Linkage Localization of TGFB2 and the Human Homeobox Gene HLX1 to Chromosome 1q 1993 ·Genomics ·Darryl Nishimura,A F Purchio,J.C. Murray	19
12	Enhanced sulfated‐proteoglycan core protein synthesis by incubation of rabbit chondrocytes with recombinant transforming growth factor‐β₁ 1991 ·Journal of Cellular Physiology ·Charles J. Malemud,(unknown),Thomas M. Hering,A F Purchio	35
13	Molecular Cloning of a Novel Bone-Forming Compound: Osteoinductive Factor 1990 ·DNA and Cell Biology ·Linda Madisen,(unknown),Gregory D. Plowman,David Rosen,Patricia R. Segarini,James R. Dasch,Andrea Y. Thompson,(unknown),H Bentz,A F Purchio	73
14	Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor 1989 ·Biochemical and Biophysical Research Communications ·Kristina S. Kovacina,George Steele-Perkins,A F Purchio,Mario N. Lioubin,Kohei Miyazono,Carl‐Henrik Heldin,Richard A. Roth	112
15	Transforming Growth Factor-β2: cDNA Cloning and Sequence Analysis 1988 ·DNA ·Linda Madisen,Nancy R. Webb,Timothy M. Rose,Hans Marquardt,Tatsuhiko N. Ikeda,Daniel R. Twardzik,Saeid M. Seyedin,A F Purchio	172
16	Structural and Sequence Analysis of TGF-β2 cDNA Clones Predicts Two Different Precursor Proteins Produced by Alternative mRNA Splicing 1988 ·DNA ·Nancy R. Webb,Linda Madisen,Timothy M. Rose,A F Purchio	49
17	Molecular Events in the Processing of Recombinant Type 1 Pre-Pro-Transforming Growth Factor Beta to the Mature Polypeptide 1988 ·Molecular and Cellular Biology ·L E Gentry,Mario N. Lioubin,A F Purchio,Hans Marquardt	74
18	Cloning and Sequence Analysis of Simian Transforming Growth Factor-β cDNA 1987 ·DNA ·(unknown),Gregory D. Plowman,Timothy M. Rose,Daniel R. Twardzik,A F Purchio	85
19	Increase in the Phosphotransferase Specific Activity of Purified Rous Sarcoma Virus pp60 ^{v- src} Protein After Incubation with ATP Plus Mg ²⁺ 1983 ·Molecular and Cellular Biology ·A F Purchio,Susan K. Wells,Marc S. Collett	15
20	Towards a molecular description of cell transformation by avian sarcoma virus 1980 ·Proceedings of the Royal Society of London. Series B, Biological sciences ·Raymond L. Erikson,Marc S. Collett,E Erikson,A F Purchio	4

About A F Purchio

A F Purchio is a scholar working on Immunology and Allergy, Genetics and Molecular Biology, having authored 85 papers that have together received 8.4k indexed citations. Recurring topics across this work include Viral Infectious Diseases and Gene Expression in Insects (20 papers), Virus-based gene therapy research (19 papers) and TGF-β signaling in diseases (11 papers). The work is most often cited by research in Immunology and Allergy (669 citations), Molecular Biology (5.1k citations) and Cancer Research (941 citations). A F Purchio has collaborated with scholars based in United States, Austria and Germany. Frequent co-authors include Marc S. Collett, L E Gentry, R L Erikson, E Erikson, Hans Marquardt, Raymond L. Erikson, Mario N. Lioubin, Harold L. Moses, Russette M. Lyons and Joan S. Brugge. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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