Deryk Loo

4.6k citations

44 papers · 3.4k indexed · 2 hit papers · h-index 21

Impact in

Immunology top 5%
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- T-cell and B-cell Immunology
Developmental Neuroscience top 5%

Papers in ⓘ

Developmental Neuroscience 5
- Neurogenesis and neuroplasticity mechanisms 4
Oncology 20
- CAR-T cell therapy research 7
- Cancer Immunotherapy and Biomarkers 6

Co-authors: Edward R. Whittemore (4 shared papers)CW Cotman (1 shared paper)Christian J. Pike (1 shared paper)Agata Copani (1 shared paper)Alejandro Aruffo (4 shared papers)David W. Barnes (9 shared papers)Jill R. Rillema (1 shared paper)Cathleen Rawson (7 shared papers)
Journals: Cancer Research (7 papers)Journal of Clinical Oncology (4 papers)Journal of Cellular Physiology (3 papers)Journal for ImmunoTherapy of Cancer (3 papers)Neuroreport (2 papers)
Partner nations: United States Germany Sweden

In The Last Decade

Deryk Loo

43 papers receiving 3.3k citations

Hit Papers

align trajectories log scale

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses 1997 · 649 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1997 The Journal of Experimental Medicine
1993 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Deryk Loo

Since Specialization

Citations

This map shows the geographic impact of Deryk Loo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Deryk Loo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Deryk Loo more than expected).

Fields of papers citing papers by Deryk Loo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Deryk Loo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Deryk Loo. The network helps show where Deryk Loo may publish in the future.

Co-authors

The 25 scholars most cited alongside Deryk Loo, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Deryk Loo Line = papers co-authored together Deryk Loo links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 44 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proceedings of the National Academy of Sciences ·Deryk Loo, Agata Copani, Christian J. Pike, Edward R. Whittemore, Andrea J. Walencewicz, CW Cotman Hit paper breakdown →	1993	891
2	4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses The Journal of Experimental Medicine ·Walter W. Shuford, Kerry Klussman, Douglas D. Tritchler, Deryk Loo, Jan Chalupny, Anthony W. Siadak, T J Brown, John Emswiler, Hong Raecho, Christian P. Larsen, Thomas C. Pearson, Jeffrey A. Ledbetter, Alejandro Aruffo, Robert S. Mittler Hit paper breakdown →	1997	649
3	A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture Neuroscience ·Edward R. Whittemore, Deryk Loo, John A. Watt, C.W. Cotmans	1995	239
4	In Situ Detection of Apoptosis by the TUNEL Assay: An Overview of Techniques Methods in molecular biology ·Deryk Loo	2010	203
5	Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons Neuroreport ·Edward R. Whittemore, Deryk Loo, Carl W. Cotman	1994	184
6	Extended Culture of Mouse Embryo Cells Without Senescence: Inhibition by Serum Science ·Deryk Loo, Janice I. Fuquay, Cathleen Rawson, David W. Barnes	1987	181
7	Chapter 14 Measurement of Cell Death Methods in cell biology ·Deryk Loo, Jill R. Rillema	1998	168
8	Filamin Binds to the Cytoplasmic Domain of the β1-Integrin Journal of Biological Chemistry ·Deryk Loo, Steven B. Kanner, Alejandro Aruffo	1998	159
9	Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in patients with refractory B7-H3-expressing neoplasms or neoplasms whose vasculature expresses B7-H3 Journal for ImmunoTherapy of Cancer ·John D. Powderly, Gregory M. Coté, Keith T. Flaherty, Russell Z. Szmulewitz, Antoni Ribas, Jeffrey S. Weber, Deryk Loo, Jan Baughman, Francine Chen, Paul A. Moore, Ezio Bonvini, James R. Vasselli, Jon M. Wigginton, Roger B. Cohen, Howard A. Burris, Bartosz Chmielowski	2015	74
10	Constitutive Expression of Functional 4-1BB (CD137) Ligand on Carcinoma Cells The Journal of Immunology ·Helmut R. Salih, Steven G. Kosowski, Vanessa F. Haluska, Gary C. Starling, Deryk Loo, Francis Lee, Alejandro Aruffo, Pamela A. Trail, Peter A. Kiener	2000	70
11	Death of serum-free mouse embryo cells caused by epidermal growth factor deprivation. The Journal of Cell Biology ·Cathleen Rawson, Deryk Loo, Julie R. Duimstra, Olaf R. Hedstrom, Edward E. Schmidt, David W. Barnes	1991	61
12	Possible Role of Apoptosis in Alzheimer's Disease Annals of the New York Academy of Sciences ·Carl W. Cotman, Edward R. Whittemore, John A. Watt, AILEEN J. ANDERSON, Deryk Loo	1994	54
13	The glycotope-specific RAV12 monoclonal antibody induces oncosis in vitro and has antitumor activity against gastrointestinal adenocarcinoma tumor xenografts in vivo Molecular Cancer Therapeutics ·Deryk Loo, Nancy Pryer, Peter Young, Tony W. Liang, Suzanne Coberly, Kathleen L. King, Key Kang, Penny Roberts, Mary C. Tsao, Xiaolin Xu, Beverly Potts, Jennie P. Mather	2007	54
14	Serum‐free mouse embryo cells: Growth responses in vitro Journal of Cellular Physiology ·Deryk Loo, Cathleen Rawson, Angela Helmrich, David W. Barnes	1989	43
15	TUNEL Assay: An Overview of Techniques Humana Press eBooks ·Deryk Loo	2003	39
16	Phase 1 dose escalation study of MGC018, an anti-B7-H3 antibody-drug conjugate (ADC), in patients with advanced solid tumors. Journal of Clinical Oncology ·Sekwon Jang, John D. Powderly, Alexander I. Spira, Ouiam Bakkacha, Deryk Loo, Gerry C. Bohac, Manish Sharma	2021	32
17	Binding of Staphylococcus aureus by human serum spreading factor in an in vitro assay Infection and Immunity ·Janice I. Fuquay, Deryk Loo, David W. Barnes	1986	31
18	Differentiation of serum‐free mouse embryo cells into astrocytes is accompanied by induction of glutamine synthetase activity Journal of Neuroscience Research ·Deryk Loo, Morgan Althoen, Carl W. Cotman	1995	29
19	Down regulation of nestin by TGF-β or serum in SFME cells accompanies differentiation into astrocytes Neuroreport ·Deryk Loo, Morgan Althoen, Carl W. Cotman	1994	26
20	Analysis of 4-1BBL and Laminin Binding to Murine 4-1BB, a Member of the Tumor Necrosis Factor Receptor Superfamily, and Comparison with Human 4-1BB Journal of Biological Chemistry ·Deryk Loo, N. Jan Chalupny, Jürgen Bajorath, Walter W. Shuford, Robert S. Mittler, Alejandro Aruffo	1997	25

About Deryk Loo

Deryk Loo is a scholar working on Developmental Neuroscience, Oncology, Immunology, Radiology, Nuclear Medicine and Imaging and Immunology and Allergy, having authored 44 papers that have together received 3.4k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (13 papers), Glycosylation and Glycoproteins Research (8 papers), Immunotherapy and Immune Responses (8 papers), CAR-T cell therapy research (7 papers), Pluripotent Stem Cells Research (7 papers), Cancer Immunotherapy and Biomarkers (6 papers), Cell death mechanisms and regulation (5 papers) and Neurogenesis and neuroplasticity mechanisms (4 papers). The work is most often cited by research in Immunology (899 citations), Developmental Neuroscience (149 citations), Physiology (827 citations), Neurology (237 citations) and Cellular and Molecular Neuroscience (512 citations). Deryk Loo has collaborated with scholars based in United States, Germany and Sweden. Frequent co-authors include Edward R. Whittemore, CW Cotman, Christian J. Pike, Agata Copani, Alejandro Aruffo, David W. Barnes, Jill R. Rillema, Cathleen Rawson, John A. Watt and Carl W. Cotman. Their work appears in journals such as Cancer Research, Journal of Clinical Oncology, Journal of Cellular Physiology, Journal for ImmunoTherapy of Cancer and Neuroreport.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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