David L. Huso

21.6k citations

155 papers · 15.3k indexed · 6 hit papers · h-index 64

Molecular Biology top 0.5%
Genetics top 0.2%
Oncology top 0.5%
Pulmonary and Respiratory Medicine top 0.5%
Cancer Research top 0.5%

Co-authors: Cynthia L. Sears Shaoguang Wu Bert Vogelstein Kenneth W. Kinzler Baktiar Karim Franck Housseau Xinqun Wu Harry C. Dietz
Topics: Cancer Cells and Metastasis (16 papers)Connective tissue disorders research (14 papers)Acute Myeloid Leukemia Research (11 papers)
Cited by: Cancer Research Genetics Biotechnology
Journals: Nature Science Cell
Partner nations: United States United Kingdom Canada

In The Last Decade

David L. Huso

154 papers receiving 15.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

2009 1.3k citations Shaoguang Wu, Xinqun Wu et al. profile →
Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome

2006 1.3k citations Jennifer Habashi, Djahida Bedja et al. Science profile →
Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

2018 782 citations Christine M. Dejea, Payam Fathi et al. Science profile →
Mutant PIK3CA promotes cell growth and invasion of human cancer cells

2005 727 citations Yardena Samuels, Luis A. Díaz et al. Cancer Cell profile →
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α

1999 542 citations David L. Huso et al. profile →
Polyamine catabolism contributes to enterotoxigenicBacteroides fragilis-induced colon tumorigenesis

2011 463 citations Christina E. DeStefano Shields, Shaoguang Wu et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by David L. Huso

Since Specialization

Citations

This map shows the geographic impact of David L. Huso's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David L. Huso with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David L. Huso more than expected).

Fields of papers citing papers by David L. Huso

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David L. Huso. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David L. Huso. The network helps show where David L. Huso may publish in the future.

Co-authorship network of co-authors of David L. Huso

This figure shows the co-authorship network connecting the top 25 collaborators of David L. Huso. A scholar is included among the top collaborators of David L. Huso based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David L. Huso. David L. Huso is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Oxytocin antagonism prevents pregnancy-associated aortic dissection in a mouse model of Marfan syndrome 2019 ·Science Translational Medicine ·Jennifer Habashi,Elena Gallo MacFarlane,Rustam Bagirzadeh,Caitlin J. Bowen,(unknown),(unknown),Djahida Bedja,Tyler J. Creamer,(unknown),Maurice Manning,David L. Huso,Harry C. Dietz	38
2	Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteriabreakdown → 2018 ·Science ·Christine M. Dejea,Payam Fathi,John M. Craig,Annemarie Boleij,Rahwa Taddese,Abby L. Geis,Xinqun Wu,Christina E. DeStefano Shields,Elizabeth M. Hechenbleikner,David L. Huso,Robert A. Anders,Francis M. Giardiello,Elizabeth C. Wick,Hao Wang,Shaoguang Wu,Drew M. Pardoll,Franck Housseau,Cynthia L. Sears	782
3	Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer 2016 ·Cancer Research ·Vanessa F. Merino,Nguyen Nguyen,Kideok Jin,Helen Sadik,Soonweng Cho,Preethi Korangath,Liangfeng Han,(unknown),Xian Zhou,Zhe Zhang,Roisín M. Connolly,Vered Stearns,Syed Z. Ali,(unknown),Qian Chen,Duojia Pan,David L. Huso,Peter Ordentlich,Angela Brodie,Saraswati Sukumar	37
4	Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis 2016 ·Cancer Research ·Franck Housseau,Shaoguang Wu,Elizabeth C. Wick,Hongni Fan,Xinqun Wu,Nicolás J. Llosa,Kellie N. Smith,Ada Tam,Sudipto Ganguly,Jane W. Wanyiri,Thevambiga Iyadorai,(unknown),April Camilla Roslani,Jamunarani S. Vadivelu,(unknown),David L. Huso,Drew M. Pardoll,Cynthia L. Sears	102
5	Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment 2016 ·PMC ·Christina E. DeStefano Shields,Sara W. Van Meerbeke,Franck Housseau,Hao Wang,David L. Huso,Robert A. Casero,(unknown),Cynthia L. Sears	3
6	Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model 2016 ·Oncotarget ·(unknown),Ren-Yuan Bai,Verena Staedtke,David L. Huso,Gregory J. Riggins	62
7	Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis 2015 ·Cancer Discovery ·Abby L. Geis,Hongni Fan,Xinqun Wu,Shaoguang Wu,David L. Huso,(unknown),Cynthia L. Sears,Drew M. Pardoll,Franck Housseau	142
8	The Notch Pathway Inhibits TGFβ Signaling in Breast Cancer through HEYL-Mediated Crosstalk 2014 ·Cancer Research ·Liangfeng Han,Adam Diehl,Nguyen K. Nguyen,Preethi Korangath,Wei Wen Teo,Soonweng Cho,Scott L. Kominsky,David L. Huso,Lionel Feigenbaum,Alan Rein,Pedram Argani,Göran Landberg,Manfred Gessler,Saraswati Sukumar	27
9	Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways 2014 ·Oncogene ·(unknown),S-H Chen,W‐C Hung,C. Paul,Fei Zhu,(unknown),David L. Huso,Aikaterini Kontrogianni‐Konstantopoulos,Κωνσταντίνος Κωνσταντόπουλος	48
10	53BP1 Is Limiting for NHEJ Repair in ATM-deficient Model Systems That Are Subjected to Oncogenic Stress or Radiation 2013 ·Molecular Cancer Research ·(unknown),Taylor L. Reynolds,(unknown),Mansi Prakash,(unknown),David L. Huso,Stephen Desiderio,Sonia Franco	13
11	Genetic inactivation of AKT1 , AKT2 , and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation 2010 ·Proceedings of the National Academy of Sciences ·Kajsa Ericson,Christine Gan,Ian Cheong,Carlo Rago,Yardena Samuels,Victor E. Velculescu,Kenneth W. Kinzler,David L. Huso,Bert Vogelstein,Nickolas Papadopoulos	106
12	Unexpected Lack of Hypersensitivity in LRRK2 Knock-Out Mice to MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) 2009 ·Journal of Neuroscience ·Eva Andrés‐Mateos,Rebeca Mejı́as,Masayuki Sasaki,Xiaojie Li,(unknown),Saskia Biskup,Li Zhang,Rebecca Banerjee,Bobby Thomas,Lichuan Yang,Guosheng Liu,M. Flint Beal,David L. Huso,Ted M. Dawson,Valina L. Dawson	95
13	Radioimmunotherapy of Breast Cancer Metastases with α-Particle Emitter 225Ac: Comparing Efficacy with 213Bi and 90Y 2009 ·Cancer Research ·Hong Song,Robert F. Hobbs,Ravy K. Vajravelu,David L. Huso,Caroline Esaias,Christos Apostolidis,Aliyah Morgenstern,George Sgouros	118
14	Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts 2008 ·Molecular Cancer Therapeutics ·Francescopaolo Di Cello,Jöelle Hillion,Jeanne Kowalski,Brigitte M. Ronnett,(unknown),David L. Huso,Linda Resar	26
15	The High-Mobility Group A1 Gene Up-Regulates Cyclooxygenase 2 Expression in Uterine Tumorigenesis 2007 ·Cancer Research ·Abeba Tesfaye,Francescopaolo Di Cello,Jöelle Hillion,Brigitte M. Ronnett,(unknown),Raheela Ashfaq,Surajit Dhara,Edward V. Prochownik,(unknown),Raymond Reeves,Richard B.S. Roden,Lora H. Ellenson,David L. Huso,Linda Resar	62
16	Tamoxifen resistance and Her2/neu expression in an aged, irradiated rat breast carcinoma model 2005 ·Carcinogenesis ·Norman Peterson,Matthew D. Servinsky,(unknown),Zhongsheng Peng,Weiping Qiu,(unknown),J. F. Dicello,David L. Huso	13
17	Mutant PIK3CA promotes cell growth and invasion of human cancer cellsbreakdown → 2005 ·Cancer Cell ·Yardena Samuels,Luis A. Díaz,Oleg Schmidt‐Kittler,Jordan M. Cummins,(unknown),Ian Cheong,Carlo Rago,David L. Huso,Christoph Lengauer,Kenneth W. Kinzler,Bert Vogelstein,Victor E. Velculescu	727
18	CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction 2003 ·The Journal of Immunology ·Ching-Tai Huang,David L. Huso,(unknown),Tianhong Wang,Gang Zhou,Eugene P. Kennedy,Charles G. Drake,David J. Morgan,Linda A. Sherman,(unknown),Drew M. Pardoll,Adam J. Adler	59
19	Combination bacteriolytic therapy for the treatment of experimental tumors 2001 ·Proceedings of the National Academy of Sciences ·Long H. Dang,Chetan Bettegowda,David L. Huso,Kenneth W. Kinzler,Bert Vogelstein	446
20	Progressive Cerebellar, Auditory, and Esophageal Dysfunction Caused by Targeted Disruption of thefrizzled-4 Gene 2001 ·Journal of Neuroscience ·Yanshu Wang,David L. Huso,Hugh Cahill,David K. Ryugo,Jeremy Nathans	121

About David L. Huso

David L. Huso is a scholar working on Genetics, Cancer Research and Oncology, having authored 155 papers that have together received 15.3k indexed citations. Recurring topics across this work include Cancer Cells and Metastasis (16 papers), Connective tissue disorders research (14 papers) and Acute Myeloid Leukemia Research (11 papers). The work is most often cited by research in Cancer Research (2.2k citations), Genetics (4.0k citations) and Biotechnology (1.1k citations). David L. Huso has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Cynthia L. Sears, Shaoguang Wu, Bert Vogelstein, Kenneth W. Kinzler, Baktiar Karim, Franck Housseau, Xinqun Wu, Harry C. Dietz, Drew M. Pardoll and Shervin Rabizadeh. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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