Robert A. Casero

24.1k total citations · 8 hit papers
259 papers, 19.6k citations indexed

About

Robert A. Casero is a scholar working on Molecular Biology, Biochemistry and Pharmacology. According to data from OpenAlex, Robert A. Casero has authored 259 papers receiving a total of 19.6k indexed citations (citations by other indexed papers that have themselves been cited), including 247 papers in Molecular Biology, 117 papers in Biochemistry and 77 papers in Pharmacology. Recurrent topics in Robert A. Casero's work include Polyamine Metabolism and Applications (208 papers), Amino Acid Enzymes and Metabolism (116 papers) and Epigenetics and DNA Methylation (82 papers). Robert A. Casero is often cited by papers focused on Polyamine Metabolism and Applications (208 papers), Amino Acid Enzymes and Metabolism (116 papers) and Epigenetics and DNA Methylation (82 papers). Robert A. Casero collaborates with scholars based in United States, Russia and Germany. Robert A. Casero's co-authors include Patrick M. Woster, Tracy Murray Stewart, Anthony E. Pegg, Laurence J. Marton, Yang Shi, Fei Lan, Philip A. Cole, Peter Mulligan, Yujiang Geno Shi and Johnathan R. Whetstine and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Robert A. Casero

259 papers receiving 19.3k citations

Hit Papers

Histone Demethylation Mediated by the Nuclear Amine Oxida... 1996 2026 2006 2016 2004 2007 1996 1998 2018 1000 2.0k 3.0k

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Robert A. Casero United States 68 16.4k 4.6k 3.2k 1.7k 1.5k 259 19.6k
Colin Funk United States 65 6.8k 0.4× 3.5k 0.8× 4.7k 1.4× 1.0k 0.6× 1.8k 1.2× 183 17.6k
Philip W. Majerus United States 88 11.3k 0.7× 1.8k 0.4× 2.5k 0.8× 1.1k 0.6× 2.4k 1.6× 231 22.9k
Anthony E. Pegg United States 84 29.1k 1.8× 11.5k 2.5× 5.3k 1.7× 2.3k 1.3× 1.3k 0.8× 544 33.4k
Frank Madeo Austria 79 14.8k 0.9× 1.7k 0.4× 1.6k 0.5× 1.1k 0.6× 762 0.5× 203 23.5k
Junken Aoki Japan 80 16.0k 1.0× 2.3k 0.5× 541 0.2× 1.0k 0.6× 1.5k 1.0× 396 21.5k
Olof Rådmark Sweden 61 7.9k 0.5× 1.5k 0.3× 2.2k 0.7× 875 0.5× 572 0.4× 174 14.7k
Harvey R. Herschman United States 81 12.5k 0.8× 1.6k 0.3× 6.0k 1.9× 3.7k 2.2× 1.3k 0.8× 330 25.2k
Eugene W. Gerner United States 50 6.7k 0.4× 2.3k 0.5× 1.5k 0.5× 1.2k 0.7× 762 0.5× 209 9.6k
Puttur D. Prasad United States 73 8.4k 0.5× 3.3k 0.7× 447 0.1× 3.1k 1.8× 993 0.7× 172 15.8k
Q W Xie United States 28 4.6k 0.3× 2.2k 0.5× 853 0.3× 831 0.5× 908 0.6× 36 15.5k

Countries citing papers authored by Robert A. Casero

Since Specialization
Citations

This map shows the geographic impact of Robert A. Casero's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert A. Casero with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert A. Casero more than expected).

Fields of papers citing papers by Robert A. Casero

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert A. Casero. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert A. Casero. The network helps show where Robert A. Casero may publish in the future.

Co-authorship network of co-authors of Robert A. Casero

This figure shows the co-authorship network connecting the top 25 collaborators of Robert A. Casero. A scholar is included among the top collaborators of Robert A. Casero based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert A. Casero. Robert A. Casero is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Jackson, Kyle W., Masanori Hayashi, Jinghang Zhang, et al.. (2025). Polyamine Depletion by D,L-α-Difluoromethylornithine Inhibits Ewing Sarcoma Metastasis by Inducing Ferroptosis. Clinical Cancer Research. 31(19). 4196–4210. 1 indexed citations
2.
Zahedi, Kamyar, Sharon Barone, Tracy Murray Stewart, et al.. (2024). Polyamine Catabolism and Its Role in Renal Injury and Fibrosis in Mice Subjected to Repeated Low-Dose Cisplatin Treatment. Biomedicines. 12(3). 640–640. 2 indexed citations
3.
Sil, Diptesh, Sudipta Panja, Raj Kumar, et al.. (2022). Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents. Molecules. 27(8). 2441–2441. 2 indexed citations
4.
Affronti, Hayley C., Aryn M. Rowsam, Spencer R. Rosario, et al.. (2020). Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy. Nature Communications. 11(1). 52–52. 46 indexed citations
5.
Travers, Meghan, Stephen M. Brown, Matthew Dunworth, et al.. (2019). DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer. Cancer Research. 79(13). 3445–3454. 82 indexed citations
6.
Stewart, Tracy Murray, Matthew Dunworth, Jackson R. Foley, Charles E. Schwartz, & Robert A. Casero. (2018). Polyamine Homeostasis in Snyder-Robinson Syndrome. SHILAP Revista de lepidopterología. 6(4). 112–112. 32 indexed citations
7.
Stewart, Tracy Murray, Christin L. Hanigan, Patrick M. Woster, Laurence J. Marton, & Robert A. Casero. (2013). Histone Deacetylase Inhibition Overcomes Drug Resistance through a miRNA-Dependent Mechanism. Molecular Cancer Therapeutics. 12(10). 2088–2099. 22 indexed citations
8.
Pegg, Anthony E. & Robert A. Casero. (2011). Polyamines. Methods in molecular biology. 8 indexed citations
9.
Belinsky, Steven A., Marcie J. Grimes, Maria A. Picchi, et al.. (2011). Combination Therapy with Vidaza and Entinostat Suppresses Tumor Growth and Reprograms the Epigenome in an Orthotopic Lung Cancer Model. Cancer Research. 71(2). 454–462. 56 indexed citations
10.
Huang, Yi, Tracy Murray Stewart, Yu Wu, et al.. (2009). Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes. Clinical Cancer Research. 15(23). 7217–7228. 158 indexed citations
11.
Carew, Jennifer S., Steffan T. Nawrocki, Jerold E. Rehg, et al.. (2008). The Novel Polyamine Analogue CGC-11093 Enhances the Antimyeloma Activity of Bortezomib. Cancer Research. 68(12). 4783–4790. 23 indexed citations
12.
Ignatenko, Natalia A., et al.. (2004). Suppression of polyamine catabolism by activated Ki‐ras in human colon cancer cells. Molecular Carcinogenesis. 39(2). 91–102. 58 indexed citations
13.
McCloskey, Diane E., Patrick M. Woster, Robert A. Casero, & Nancy E. Davidson. (2000). Effects of the polyamine analogues N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-ethylN-11-((cycloheptyl)methyl)-4,8-diazaundecane in human prostate cancer cells.. PubMed. 6(1). 17–23. 32 indexed citations
14.
Gabrielson, Edward, Anthony E. Pegg, & Robert A. Casero. (1999). The induction of spermidine/spermine N1-acetyltransferase (SSAT) is a common event in the response of human primary non-small cell lung carcinomas to exposure to the new antitumor polyamine analogue N1,N11-bis(ethyl)norspermine.. PubMed. 5(7). 1638–41. 34 indexed citations
15.
Xiao, Lei, et al.. (1998). Two active copies of the X-linked gene spermidine/spermine N1-acetyltransferase (SSAT) in a female lung cancer cell line are associated with an increase in sensitivity to an antitumor polyamine analogue.. PubMed. 4(8). 2003–8. 20 indexed citations
16.
Campbell, Susan, et al.. (1998). The growth inhibitory effect of N1,N12-bis(ethyl)spermine in small cell lung cancer cells is maintained in cells expressing the c-myc and Ha-ras oncogenes.. PubMed. 4(6). 1557–61. 4 indexed citations
17.
McCloskey, Diane E., Robert A. Casero, Patrick M. Woster, & Nancy E. Davidson. (1995). Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue.. PubMed. 55(15). 3233–6. 72 indexed citations
18.
Casero, Robert A., Edward Gabrielson, & Anthony E. Pegg. (1994). Immunohistochemical staining of human spermidine/spermine N1-acetyltransferase superinduced in response to treatment with antitumor polyamine analogues.. PubMed. 54(15). 3955–8. 29 indexed citations
19.
Davidson, Nancy E., et al.. (1993). Growth inhibition of hormone-responsive and -resistant human breast cancer cells in culture by N1, N12-bis(ethyl)spermine.. PubMed. 53(9). 2071–5. 55 indexed citations
20.
Casero, Robert A., et al.. (1992). Steady-state messenger RNA and activity correlates with sensitivity to N1,N12-bis(ethyl)spermine in human cell lines representing the major forms of lung cancer.. PubMed. 52(19). 5359–63. 76 indexed citations

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