David Cortez

22.7k total citations · 6 hit papers
114 papers, 16.6k citations indexed

About

David Cortez is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, David Cortez has authored 114 papers receiving a total of 16.6k indexed citations (citations by other indexed papers that have themselves been cited), including 110 papers in Molecular Biology, 38 papers in Oncology and 23 papers in Cell Biology. Recurrent topics in David Cortez's work include DNA Repair Mechanisms (95 papers), Genomics and Chromatin Dynamics (29 papers) and Cancer-related Molecular Pathways (24 papers). David Cortez is often cited by papers focused on DNA Repair Mechanisms (95 papers), Genomics and Chromatin Dynamics (29 papers) and Cancer-related Molecular Pathways (24 papers). David Cortez collaborates with scholars based in United States, France and Canada. David Cortez's co-authors include Stephen J. Elledge, Karlene A. Cimprich, Gloria G. Glick, Jun Qin, Yi Wang, Bianca M. Sirbu, Ann Marie Pendergast, Kamakoti P. Bhat, Courtney A. Lovejoy and Joshua C. Saldivar and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

David Cortez

112 papers receiving 16.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chk1 is an essential kinase that is regulated by Atr and required for the G₂/M DNA damage checkpoint

2000 1.3k citations David Cortez, Stephen J. Elledge et al. profile →
ATR: an essential regulator of genome integrity

2008 1.3k citations Karlene A. Cimprich, David Cortez Nature Reviews Molecular Cell Biology profile →
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

2000 991 citations David Cortez, Stephen J. Elledge et al. profile →
Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks

1999 806 citations David Cortez, Stephen J. Elledge et al. Science profile →
ATR and ATRIP: Partners in Checkpoint Signaling

2001 744 citations David Cortez, Stephen J. Elledge et al. Science profile →
The essential kinase ATR: ensuring faithful duplication of a challenging genome

2017 573 citations Joshua C. Saldivar, David Cortez et al. Nature Reviews Molecular Cell Biology profile →

Peers

Countries citing papers authored by David Cortez

Since Specialization

Citations

This map shows the geographic impact of David Cortez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Cortez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Cortez more than expected).

Fields of papers citing papers by David Cortez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Cortez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Cortez. The network helps show where David Cortez may publish in the future.

Co-authorship network of co-authors of David Cortez

This figure shows the co-authorship network connecting the top 25 collaborators of David Cortez. A scholar is included among the top collaborators of David Cortez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David Cortez. David Cortez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms 2025 ·Nucleic Acids Research ·(unknown), (unknown), David Cortez, James M. Dewar	0
2	Contributing factors to the oxidation-induced mutational landscape in human cells 2024 ·Nature Communications ·(unknown), Kavi P.M. Mehta, Tyler Weaver, (unknown), Bret Freudenthal, David Cortez, Steven A. Roberts	6
3	Structure of RADX and mechanism for regulation of RAD51 nucleofilaments 2024 ·Proceedings of the National Academy of Sciences ·(unknown), Madison B. Adolph, Miaw-Sheue Tsai, (unknown), (unknown), David Cortez, Walter Chazin	2
4	RAD51 bypasses the CMG helicase to promote replication fork reversal 2023 ·Science ·Wenpeng Liu, Yuichiro Saito, Jessica Jackson, Rahul Bhowmick, Masato T. Kanemaki, Alessandro Vindigni, David Cortez	55
5	CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity 2023 ·Journal of Molecular Biology ·Madison B. Adolph, (unknown), (unknown), (unknown), Mauro Modesti, Walter Chazin, David Cortez	2
6	Self-reversal facilitates the resolution of HMCES DNA-protein crosslinks in cells 2023 ·Cell Reports ·(unknown), Courtney A. Lovejoy, Kavi P.M. Mehta, (unknown), (unknown), (unknown), Brandt F. Eichman, David Cortez	14
7	Replication fork uncoupling causes nascent strand degradation and fork reversal 2023 ·Nature Structural & Molecular Biology ·(unknown), Wenpeng Liu, (unknown), David Cortez, James M. Dewar	19
8	Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability 2023 ·Molecular Cell ·Rahul Bhowmick, Kavi P.M. Mehta, Mads Lerdrup, David Cortez	16
9	CHK1 phosphorylates PRIMPOL to promote replication stress tolerance 2022 ·Science Advances ·Kavi P.M. Mehta, (unknown), Runxiang Zhao, (unknown), Micheal Leser, Kristie L. Rose, David Cortez	37
10	Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms 2022 ·The EMBO Journal ·(unknown), Kavi P.M. Mehta, (unknown), Jo Ann W. Byl, Runxiang Zhao, Neil Osheroff, David Cortez, James M. Dewar	21
11	ATR activation is regulated by dimerization of ATR activating proteins 2021 ·Journal of Biological Chemistry ·(unknown), David Cortez	17
12	Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors 2020 ·Science Advances ·Wenpeng Liu, (unknown), Runxiang Zhao, David Cortez	63
13	New insights into abasic site repair and tolerance 2020 ·DNA repair ·Petria S. Thompson, David Cortez	102
14	The plasticity of DNA replication forks in response to clinically relevant genotoxic stress 2020 ·Nature Reviews Molecular Cell Biology ·Matteo Berti, David Cortez, Massimo Lopes	233
15	Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1 2019 ·The Journal of Cell Biology ·Thomas E. Bass, David Cortez	40
16	Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link 2019 ·Nature Structural & Molecular Biology ·Petria S. Thompson, (unknown), Kareem N. Mohni, David Cortez, Brandt F. Eichman	72
17	An intrinsic S/G ₂ checkpoint enforced by ATR 2018 ·Science ·Joshua C. Saldivar, Stephan Hamperl, M Bocek, Mingyu Chung, Thomas E. Bass, Fernanda Cisneros-Soberanis, Kumiko Samejima, Linfeng Xie, James R. Paulson, William C. Earnshaw, David Cortez, Tobias Meyer, Karlene A. Cimprich	203
18	ATR Pathway Inhibition Is Synthetically Lethal in Cancer Cells with ERCC1 Deficiency 2014 ·Cancer Research ·Kareem N. Mohni, Gina M. Kavanaugh, David Cortez	108
19	Dpb11 activates the Mec1–Ddc2 complex 2008 ·Proceedings of the National Academy of Sciences ·Daniel A. Mordes, Edward A. Nam, David Cortez	100
20	Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases 2004 ·Proceedings of the National Academy of Sciences ·David Cortez, Gloria G. Glick, Stephen J. Elledge	260

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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