Karen Bush

30.6k total citations · 10 hit papers
218 papers, 22.7k citations indexed

About

Karen Bush is a scholar working on Molecular Medicine, Pharmacology and Molecular Biology. According to data from OpenAlex, Karen Bush has authored 218 papers receiving a total of 22.7k indexed citations (citations by other indexed papers that have themselves been cited), including 150 papers in Molecular Medicine, 99 papers in Pharmacology and 60 papers in Molecular Biology. Recurrent topics in Karen Bush's work include Antibiotic Resistance in Bacteria (150 papers), Antibiotics Pharmacokinetics and Efficacy (81 papers) and Antimicrobial Resistance in Staphylococcus (39 papers). Karen Bush is often cited by papers focused on Antibiotic Resistance in Bacteria (150 papers), Antibiotics Pharmacokinetics and Efficacy (81 papers) and Antimicrobial Resistance in Staphylococcus (39 papers). Karen Bush collaborates with scholars based in United States, Malaysia and Switzerland. Karen Bush's co-authors include George A. Jacoby, Anne Marie Queenan, Patricia A. Bradford, Antone A. Medeiros, B A Rasmussen, Mark J. Macielag, R. B. Sykes, Darren Abbanat, George M. Eliopoulos and James W. Biddle and has published in prestigious journals such as Nature, Science and Journal of the American Chemical Society.

In The Last Decade

Karen Bush

217 papers receiving 21.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Carbapenemases: the Versatile β-Lactamases

2007 1.9k citations Anne Marie Queenan, Karen Bush profile →
A functional classification scheme for beta-lactamases and its correlation with molecular structure

1995 1.9k citations Karen Bush, George A. Jacoby et al. Antimicrobial Agents and Chemotherapy profile →
Updated Functional Classification of β-Lactamases

2009 1.7k citations Karen Bush, George A. Jacoby Antimicrobial Agents and Chemotherapy profile →
Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain ofKlebsiella pneumoniae

2001 1.3k citations Anne Marie Queenan, Karen Bush et al. Antimicrobial Agents and Chemotherapy profile →
β-Lactams and β-Lactamase Inhibitors: An Overview

2016 825 citations Karen Bush, Patricia A. Bradford profile →
Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase

2005 750 citations Ari Robicsek, Jacob Strahilevitz et al. Nature Medicine profile →
Past and Present Perspectives on β-Lactamases

2018 587 citations Karen Bush Antimicrobial Agents and Chemotherapy profile →
Epidemiology of β-Lactamase-Producing Pathogens

2020 564 citations Karen Bush, Patricia A. Bradford profile →
Interplay between β-lactamases and new β-lactamase inhibitors

2019 373 citations Karen Bush, Patricia A. Bradford Nature Reviews Microbiology profile →
Critical analysis of antibacterial agents in clinical development

2020 268 citations Ursula Theuretzbacher, Karen Bush et al. Nature Reviews Microbiology profile →

Peers

Karen Bush

PHARM

ENDOC

EPIDE

David C. Hooper United States

George A. Jacoby United States

Gian María Rossolini Italy

Timothy R. Walsh United Kingdom

David M. Livermore United Kingdom

Neil Woodford United Kingdom

Yohei Doi United States

Rafael Cantón Spain

Laura J. V. Piddock United Kingdom

Christian G. Giske Sweden

David C. Hooper United States

Karen Bush

12.8k ×0.7

7.0k ×1.0

PHARM

6.7k ×1.1

3.5k ×0.6

ENDOC

4.8k ×1.1

EPIDE

Citations per year, relative to Karen Bush Karen Bush (= 1×) peers David C. Hooper

Countries citing papers authored by Karen Bush

Since Specialization

Citations

This map shows the geographic impact of Karen Bush's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karen Bush with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karen Bush more than expected).

Fields of papers citing papers by Karen Bush

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karen Bush. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karen Bush. The network helps show where Karen Bush may publish in the future.

Co-authorship network of co-authors of Karen Bush

This figure shows the co-authorship network connecting the top 25 collaborators of Karen Bush. A scholar is included among the top collaborators of Karen Bush based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karen Bush. Karen Bush is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Spencer, James, Bogdan I. Iorga, Jean‐Denis Docquier, et al.. (2025). SAND: a comprehensive annotation of class D β-lactamases using structural alignment-based numbering. Antimicrobial Agents and Chemotherapy. 69(7). e0015025–e0015025. 2 indexed citations

Bush, Karen, M. Elaine Husni, Soumya M. Reddy, et al.. (2025). Diverse Treatment Goals in Psoriatic Arthritis: Insights From Participants in the PARC Cohort. Arthritis Care & Research. 77(8). 1007–1013.

Bush, Karen. (2025). Past, present, and future perspectives on aztreonam and avibactam. Expert Review of Anti-infective Therapy. 23(5). 277–290. 3 indexed citations

Reddy, Soumya M., Karen Bush, M. Elaine Husni, et al.. (2023). AB1122 GUSELKUMAB VS GOLIMUMAB IN PSA TNFI-INADEQUATE RESPONDERS (EVOLUTION): FORMULATING A PRAGMATIC PHASE 3B RANDOMIZED TRIAL. Annals of the Rheumatic Diseases. 82. 1791–1791. 1 indexed citations

Bradford, Patricia A., Robert A. Bonomo, Karen Bush, et al.. (2022). Consensus on β-Lactamase Nomenclature. Antimicrobial Agents and Chemotherapy. 66(4). e0033322–e0033322. 16 indexed citations

Theuretzbacher, Ursula, Karen Bush, Stéphan Harbarth, et al.. (2020). Critical analysis of antibacterial agents in clinical development. Nature Reviews Microbiology. 18(5). 286–298. 268 indexed citations breakdown →

Bush, Karen & Patricia A. Bradford. (2019). Author Correction: Interplay between β-lactamases and new β-lactamase inhibitors. Nature Reviews Microbiology. 17(7). 459–460. 6 indexed citations

Bush, Karen. (2012). Improving known classes of antibiotics: an optimistic approach for the future. Current Opinion in Pharmacology. 12(5). 527–534. 81 indexed citations

Bush, Karen & Michael J. Pucci. (2011). New antimicrobial agents on the horizon. Biochemical Pharmacology. 82(11). 1528–1539. 43 indexed citations

10.

Bush, Karen. (2011). Introduction to Antimicrobial Therapeutics Reviews. Annals of the New York Academy of Sciences. 1241(1). vii–ix. 2 indexed citations

11.

Bush, Karen. (2008). Extended-spectrum β-lactamases in North America, 1987–2006. Clinical Microbiology and Infection. 14. 134–143. 122 indexed citations

12.

Baum, Ellen Z., Steven M. Crespo‐Carbone, Alexandra L. Klinger, et al.. (2007). A MurF Inhibitor That Disrupts Cell Wall Biosynthesis in Escherichia coli. Antimicrobial Agents and Chemotherapy. 51(12). 4420–4426. 37 indexed citations

13.

Fakioglu, Esra, et al.. (2006). Amp C β-lactamase-producing Escherichia coli in neonatal meningitis: diagnostic and therapeutic challenge. Journal of Perinatology. 26(8). 515–517. 10 indexed citations

14.

Lolans, Karen, et al.. (2005). First Nosocomial Outbreak of Pseudomonas aeruginosa Producing an Integron-Borne Metallo-β-Lactamase (VIM-2) in the United States. Antimicrobial Agents and Chemotherapy. 49(8). 3538–3540. 98 indexed citations

15.

Robicsek, Ari, Jacob Strahilevitz, George A. Jacoby, et al.. (2005). Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nature Medicine. 12(1). 83–88. 750 indexed citations breakdown →

16.

Bush, Karen, Mark J. Macielag, & Michele A. Weidner‐Wells. (2004). Taking inventory: antibacterial agents currently at or beyond Phase 1. Current Opinion in Microbiology. 7(5). 466–476. 87 indexed citations

17.

Foleno, Barbara D., Raúl Goldschmidt, Dennis J. Hlasta, et al.. (2003). Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones. Bioorganic & Medicinal Chemistry Letters. 13(23). 4173–4177. 37 indexed citations

18.

Wong‐Beringer, Annie, Janet A. Hindler, Anne Marie Queenan, et al.. (2002). Molecular Correlation for the Treatment Outcomes in Bloodstream Infections Caused byEscherichia coliandKlebsiella pneumoniaewith Reduced Susceptibility to Ceftazidime. Clinical Infectious Diseases. 34(2). 135–146. 110 indexed citations

19.

Bush, Karen. (1997). Antimicrobial agents. Current Opinion in Chemical Biology. 1(2). 169–175. 25 indexed citations

20.

Bush, Karen, D P Bonner, & R. B. Sykes. (1980). Izumenolide - a novel .BETA.-lactamase inhibitor produced by Micromonospora. II. Biological properties.. The Journal of Antibiotics. 33(11). 1262–1269. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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