David Alexander Brown

21.0k citations

377 papers · 17.3k · 1 hit paper · h-index 72

Impact in

Rheumatology top 0.05%
- GDF15 and Related Biomarkers
Physiology top 0.5%
- Nutrition and Health in Aging

Papers in

Rheumatology 75
- GDF15 and Related Biomarkers 62
Immunology 61
- Macrophage Migration Inhibitory Factor 42

Co-authors: Samuel N. Breit (69 shared papers)Vicky Wang-Wei Tsai (25 shared papers)Asne R. Bauskin (14 shared papers)Russell L. Moore (10 shared papers)Saame Raza Shaikh (14 shared papers)Brian ORourke (6 shared papers)WILLIAM K. GLASS (27 shared papers)Amanda Salis (7 shared papers)
Journals: Inorganica Chimica Acta (17 papers)Inorganic Chemistry (12 papers)PLoS ONE (10 papers)Pathology (7 papers)International Journal of Cancer (5 papers)
Partner nations: United States Australia United Kingdom

In The Last Decade

David Alexander Brown

362 papers receiving 16.7k citations

David Alexander Brown's Hit Papers

align trajectories log scale

Mitochondrial function as a therapeutic target in heart failure 2016 · 639 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2016 Nature Reviews Cardiology

Peers

Countries citing papers authored by David Alexander Brown

Since Specialization

Citations

This map shows the geographic impact of David Alexander Brown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Alexander Brown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Alexander Brown more than expected).

Fields of papers citing papers by David Alexander Brown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Alexander Brown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Alexander Brown. The network helps show where David Alexander Brown may publish in the future.

Co-authors

The 25 scholars most cited alongside David Alexander Brown, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Alexander Brown Line = papers co-authored together David Alexander Brown links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 377 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Mitochondrial function as a therapeutic target in heart failure Nature Reviews Cardiology ·David Alexander Brown, Justin B. Perry, Mitchell E. Allen, Hani N. Sabbah, Brian L. Stauffer, Saame Raza Shaikh, John George Franklin Cleland, Wilson S. Colucci Hit paper breakdown →	2016	639
2	Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1 Nature Medicine ·Heiko Johnen, Shu Lin, Támara Kuffner, David Alexander Brown, Vicky Wang-Wei Tsai, Asne R. Bauskin, Liyun Wu, Greg J. Pankhurst	2007	521
3	Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum Proceedings of the National Academy of Sciences ·John B. Welsh, Lisa M. Sapinoso, Suzanne G. Kern, David Alexander Brown, Tao Liu, Asne R. Bauskin, Robyn Lynne Ward, Nicholas John Hawkins	2003	427
4	GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation Circulation Research ·Jian Xu, Thomas R. Kimball, John N. Lorenz, David Alexander Brown, Asne R. Bauskin, Raisa Klevitsky, Timothy Edwin Hewett, Samuel N. Breit	2006	419
5	The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases Cell Metabolism ·Vicky Wang-Wei Tsai, Yasmin Husaini, Amanda Salis, David Alexander Brown, Samuel N. Breit	2018	333
6	Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin The Lancet Psychiatry ·Thomas Arthur Pollak, Belinda Lennox, Sabine Müller, Michael E. Benros, Harald Prüß, Ludger Tebartz van Elst, Hans Christiaan Klein, Johann Steiner	2019	271
7	Macrophage inhibitory cytokine‐1 (MIC‐1/GDF15): a new marker of all‐cause mortality Aging Cell ·Fredrik E. Wiklund, Anna M. Bennet, Patrik K. E. Magnusson, Ulrika K. Eriksson, Fredrik Lindmark, Liyun Wu, Nasreen Yaghoutyfam, Christopher Peter Marquis	2010	248
8	MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma. PubMed ·David Alexander Brown, Robyn Lynne Ward, Philip Buckhaults, Tao Liu, Katharine E. Romans, Nicholas John Hawkins, Asne R. Bauskin, Kenneth W. Kinzler	2003	245
9	Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers Clinical Cancer Research ·Jens Koopmann, Phillip Buckhaults, David Alexander Brown, MARIANNA L. ZAHURAK, Norihiro Sato, Noriyoshi Fukushima, Lori J. Sokoll, Daniel W. Chan	2004	240
10	Signaling Microdomains Define the Specificity of Receptor-Mediated InsP3 Pathways in Neurons Neuron ·Patrick Delmas, Nicolas Wanaverbecq, Fe C. Abogadie, Mohini Mistry, David Alexander Brown	2002	234
11	Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study The Lancet ·David Alexander Brown, Samuel N. Breit, Julie E. Buring, Walter Douglas Fairlie, Asne R. Bauskin, Tao Liu, Paul M. Ridker	2002	231
12	Role of Macrophage Inhibitory Cytokine-1 in Tumorigenesis and Diagnosis of Cancer Cancer Research ·Asne R. Bauskin, David Alexander Brown, Támara Kuffner, Heiko Johnen, Xiaohe Luo, Mark I Hunter, Samuel N. Breit	2006	220
13	AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists Nature Neuroscience ·Naoto Hoshi, Jia-Sheng Zhang, Miho Omaki, Takahiro Takeuchi, Shigeru Yokoyama, Nicolas Wanaverbecq, Lorene K. Langeberg, Yukio Yoneda	2003	213
14	The TGF-β superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism Growth Factors ·Samuel N. Breit, Heiko Johnen, Andrew D. Cook, Vicky Wang-Wei Tsai, Mohammad G. Mohammad, Támara Kuffner, Hong Ping Zhang, Christopher Peter Marquis	2011	213
15	Cardiac mitochondria and arrhythmias Cardiovascular Research ·David Alexander Brown, Brian ORourke	2010	194
16	Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets PLoS ONE ·Laurence Macia, Vicky Wang-Wei Tsai, Amy Nguyen, Heiko Johnen, Támara Kuffner, Yan‐Chuan Shi, Shu Lin, Herbert Herzog	2012	192
17	Serum Markers in Patients with Resectable Pancreatic Adenocarcinoma: Macrophage Inhibitory Cytokine 1 versus CA19-9 Clinical Cancer Research ·Jens Koopmann, C. Nicole Rosenzweig, Zhen Zhang, Marcia Irene Canto, David Alexander Brown, Mark I Hunter, Charles J. Yeo, Daniel W. Chan	2006	186
18	Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis The Journal of Comparative Neurology ·David Alexander Brown, Paul E. Sawchenko	2007	178
19	The Transforming Growth Factor-β Superfamily Cytokine Macrophage Inhibitory Cytokine-1 Is Present in High Concentrations in the Serum of Pregnant Women1 The Journal of Clinical Endocrinology & Metabolism ·Anthony G. Moore, David Alexander Brown, Walter Douglas Fairlie, Asne R. Bauskin, Peter K. Brown, M. L. C. Munier, Patricia K. Russell, Lois A. Salamonsen	2000	170
20	TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator PLoS ONE ·Vicky Wang-Wei Tsai, Laurence Macia, Heiko Johnen, Támara Kuffner, Rakesh Manadhar, Sebastian B. Jørgensen, Ka Ki Michelle Lee-Ng, Hong Ping Zhang	2013	162

About David Alexander Brown

David Alexander Brown is a scholar working on Rheumatology, Immunology, Pathology and Forensic Medicine, Organic Chemistry and Oncology, having authored 377 papers that have together received 17.3k indexed citations. Recurring topics across this work include GDF15 and Related Biomarkers (62 papers), Macrophage Migration Inhibitory Factor (42 papers), Nutrition and Health in Aging (31 papers), Mitochondrial Function and Pathology (24 papers), Metal complexes synthesis and properties (23 papers), Cardiac Ischemia and Reperfusion (19 papers), Inorganic and Organometallic Chemistry (17 papers) and Chemical Thermodynamics and Molecular Structure (11 papers). The work is most often cited by research in Rheumatology (5.0k citations), Physiology (3.5k citations), Immunology (2.7k citations), Biological Psychiatry (247 citations) and Physiology (407 citations). David Alexander Brown has collaborated with scholars based in United States, Australia and United Kingdom. Frequent co-authors include Samuel N. Breit, Vicky Wang-Wei Tsai, Asne R. Bauskin, Russell L. Moore, Saame Raza Shaikh, Brian ORourke, WILLIAM K. GLASS, Amanda Salis, Yasmin Husaini and Tao Liu. Their work appears in journals such as Inorganica Chimica Acta, Inorganic Chemistry, PLoS ONE, Pathology and International Journal of Cancer.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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David Alexander Brown's Hit Papers

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