Brian O’Rourke

28.5k total citations · 4 hit papers
281 papers, 21.3k citations indexed

About

Brian O’Rourke is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Pathology and Forensic Medicine. According to data from OpenAlex, Brian O’Rourke has authored 281 papers receiving a total of 21.3k indexed citations (citations by other indexed papers that have themselves been cited), including 206 papers in Molecular Biology, 118 papers in Cardiology and Cardiovascular Medicine and 70 papers in Pathology and Forensic Medicine. Recurrent topics in Brian O’Rourke's work include Mitochondrial Function and Pathology (104 papers), Cardiac electrophysiology and arrhythmias (83 papers) and Cardiac Ischemia and Reperfusion (70 papers). Brian O’Rourke is often cited by papers focused on Mitochondrial Function and Pathology (104 papers), Cardiac electrophysiology and arrhythmias (83 papers) and Cardiac Ischemia and Reperfusion (70 papers). Brian O’Rourke collaborates with scholars based in United States, United Kingdom and Germany. Brian O’Rourke's co-authors include Eduardo Marbán, Miguel A. Aon, Sonia Cortassa, Ting Liu, Raimond L. Winslow, Toshiaki Sato, Yongge Liu, Christoph Maack, Ion A. Hobai and Gordon F. Tomaselli and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Brian O’Rourke

274 papers receiving 21.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mitochondrial ATP-Dependent Potassium Channels

1998 708 citations Brian O’Rourke, Eduardo Marbán et al. Circulation profile →
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms

2002 633 citations Brian O’Rourke et al. profile →
Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, II

1999 627 citations Raimond L. Winslow, Eduardo Marbán et al. Circulation Research profile →
Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

2019 302 citations Ting Liu, Brian O’Rourke et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Brian O’Rourke United States	80	13.2k	7.6k	5.6k	3.0k	2.9k	281	21.3k
Elizabeth Murphy United States	79	11.0k 0.8×	4.9k 0.6×	5.9k 1.1×	1.9k 0.6×	3.7k 1.3×	265	21.0k
Colin G. Nichols United States	67	12.3k 0.9×	5.8k 0.8×	5.6k 1.0×	4.6k 1.5×	1.2k 0.4×	311	19.0k
Daria Mochly‐Rosen United States	88	17.3k 1.3×	3.6k 0.5×	4.4k 0.8×	3.4k 1.1×	3.9k 1.3×	319	26.1k
Rainer Schulz Germany	78	7.8k 0.6×	8.1k 1.1×	8.0k 1.4×	972 0.3×	3.0k 1.0×	399	22.4k
Masafumi Kitakaze Japan	74	6.1k 0.5×	8.2k 1.1×	3.8k 0.7×	1.0k 0.3×	2.8k 1.0×	474	19.4k
Andrew P. Halestrap United Kingdom	97	22.5k 1.7×	2.0k 0.3×	5.7k 1.0×	4.1k 1.4×	6.7k 2.3×	228	35.3k
Stephen F. Vatner United States	88	8.5k 0.6×	12.5k 1.7×	3.0k 0.5×	1.3k 0.4×	3.7k 1.3×	402	23.7k
Frances M. Ashcroft United Kingdom	78	13.6k 1.0×	3.0k 0.4×	6.0k 1.1×	4.5k 1.5×	2.7k 0.9×	283	25.5k
Masatsugu Hori Japan	91	10.7k 0.8×	11.3k 1.5×	3.1k 0.5×	2.3k 0.7×	3.0k 1.0×	537	33.2k
Eduardo Marbán United States	120	26.5k 2.0×	21.2k 2.8×	7.8k 1.4×	7.2k 2.4×	2.6k 0.9×	526	45.9k

Countries citing papers authored by Brian O’Rourke

Since Specialization

Citations

This map shows the geographic impact of Brian O’Rourke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian O’Rourke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian O’Rourke more than expected).

Fields of papers citing papers by Brian O’Rourke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian O’Rourke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian O’Rourke. The network helps show where Brian O’Rourke may publish in the future.

Co-authorship network of co-authors of Brian O’Rourke

This figure shows the co-authorship network connecting the top 25 collaborators of Brian O’Rourke. A scholar is included among the top collaborators of Brian O’Rourke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian O’Rourke. Brian O’Rourke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kumar, Gayathri S., Amanda Cole, Lieven Annemans, et al.. (2024). Evolving assessment pathways for precision oncology medicines to improve patient access: a tumor-agnostic lens. The Oncologist. 29(6). 465–472.

Kurz, Felix T., Miguel A. Aon, Heinz‐Peter Schlemmer, et al.. (2023). Fractal dynamics of individual mitochondrial oscillators measure local inter-mitochondrial coupling. Biophysical Journal. 122(8). 1459–1469. 1 indexed citations

Coşarderelioğlu, Çağlar, Simion Kreimer, Pablo A. Iglesias, et al.. (2023). Decoding Angiotensin Receptors: TOMAHAQ‐Based Detection and Quantification of Angiotensin Type‐1 and Type‐2 Receptors. Journal of the American Heart Association. 12(18). e030791–e030791. 2 indexed citations

Jani, Vivek, Yuejin Wu, Ting Liu, et al.. (2021). PDE1 Inhibition Modulates Ca _v 1.2 Channel to Stimulate Cardiomyocyte Contraction. Circulation Research. 129(9). 872–886. 12 indexed citations

Moyer, Adam L., Congshan Sun, Ting Liu, et al.. (2021). Mss51 deletion increases endurance and ameliorates histopathology in the mdx mouse model of Duchenne muscular dystrophy. The FASEB Journal. 35(2). e21276–e21276. 9 indexed citations

Viswanathan, Meera, Kathleen C. Woulfe, William M. Schmidt, et al.. (2020). TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction. Proceedings of the National Academy of Sciences. 117(31). 18822–18831. 24 indexed citations

Augustynek, Bartłomiej, et al.. (2019). Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel. International Journal of Molecular Sciences. 20(21). 5323–5323. 33 indexed citations

Golden, Sherita Hill, Eric B Bass, Stephen A. Berry, et al.. (2018). Building Leadership Capacity for Mission Execution in a Large Academic Department of Medicine. The American Journal of Medicine. 132(4). 535–543.

Vakrou, Styliani, Ryuya Fukunaga, D. Brian Foster, et al.. (2018). Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models. JCI Insight. 3(6). 31 indexed citations

10.

Afzal, Junaid, et al.. (2013). Enhanced Tissue Production through Redox Control in Stem Cell-Laden Hydrogels. Tissue Engineering Part A. 19(17-18). 2014–2023. 13 indexed citations

11.

Kembro, Jackelyn Melissa, Miguel A. Aon, Raimond L. Winslow, Brian O’Rourke, & Sonia Cortassa. (2013). Integrating Mitochondrial Energetics, Redox and Ros Metabolic Networks: A Two-Compartment Model. Biophysical Journal. 104(2). 657a–657a. 1 indexed citations

12.

Foster, D. Brian, Alice Ho, Jasma Rucker, et al.. (2012). Mitochondrial ROMK Channel Is a Molecular Component of MitoK _ATP. Circulation Research. 111(4). 446–454. 164 indexed citations

13.

Barth, Andreas S., Yiqiang Zhang, Tao‐Sheng Li, et al.. (2012). Functional Impairment of Human Resident Cardiac Stem Cells by the Cardiotoxic Antineoplastic Agent Trastuzumab. Stem Cells Translational Medicine. 1(4). 289–297. 34 indexed citations

14.

Kohlhaas, Michael, Ting Liu, Andreas Knopp, et al.. (2010). Elevated Cytosolic Na ⁺ Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes. Circulation. 121(14). 1606–1613. 259 indexed citations

15.

Reynolds, Rebecca M., Brian R. Walker, Sally Haw, et al.. (2010). Low serum cortisol predicts early death after acute myocardial infarction. Critical Care Medicine. 38(3). 973–975. 22 indexed citations

16.

O’Rourke, Brian & Lothar A. Blatter. (2009). Mitochondrial Ca2+ uptake: Tortoise or hare?. Journal of Molecular and Cellular Cardiology. 46(6). 767–774. 86 indexed citations

17.

Liu, Ting, David A. Brown, & Brian O’Rourke. (2009). Cgp-37157 Abrogates The Adverse Effect Of Ouabain On Mitochondrial Energetics. Biophysical Journal. 96(3). 243a–243a. 2 indexed citations

18.

O’Rourke, Brian & Christoph Maack. (2007). The role of Na dysregulation in cardiac disease and how it impacts electrophysiology. Drug Discovery Today Disease Models. 4(4). 207–217. 19 indexed citations

19.

Ganesan, Anand N., Christoph Maack, David C. Johns, Agnieszka Sidor, & Brian O’Rourke. (2006). β-Adrenergic Stimulation of L-type Ca ²⁺ Channels in Cardiac Myocytes Requires the Distal Carboxyl Terminus of α _1C but Not Serine 1928. Circulation Research. 98(2). e11–8. 88 indexed citations

20.

Balke, C. William, William C. Rose, Brian O’Rourke, et al.. (1993). Biophysics and physiology of cardiac calcium channels. Circulation. 87(6). 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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