David A. Matthews

16.6k citations

139 papers · 8.8k indexed · 2 hit papers · h-index 51

Impact in

Infectious Diseases top 0.5%
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
Virology top 2%

Papers in

Infectious Diseases 45
- Viral gastroenteritis research and epidemiology 18
- Viral Infections and Vectors 12
Virology 7

Co-authors: J. Kraut J.T. Bolin David J. Filman W. C. Russell R. Hamlin Zuzana Hostomska Richard A. Alden C. R. Pringle
Journals: Journal of General Virology (16 papers)Journal of Biological Chemistry (12 papers)Journal of Virology (9 papers)Journal of Medicinal Chemistry (7 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)
Partner nations: United Kingdom United States Singapore

In The Last Decade

David A. Matthews

135 papers receiving 8.4k citations

Hit Papers

align trajectories log scale

The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets 2021 · 464 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2021 Nature Microbiology
1982 Journal of Biological Chemistry

Peers

Countries citing papers authored by David A. Matthews

Since Specialization

Citations

This map shows the geographic impact of David A. Matthews's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. Matthews with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. Matthews more than expected).

Fields of papers citing papers by David A. Matthews

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. Matthews. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. Matthews. The network helps show where David A. Matthews may publish in the future.

Co-authors

The 25 scholars most cited alongside David A. Matthews, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David A. Matthews Line = papers co-authored together David A. Matthews links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	SARS-CoV-2 infection enhancement by amphotericin B: implications for disease management Journal of Virology ·Dung Nguyen, Stephen M. Laidlaw, Xiaofeng Dong, Matthew E. Wand, Amanda Horton, Mark A. Sutton, Julia A. Tree, Rachel Milligan, Maximillian Erdmann, David A. Matthews, Andrew D. Davidson, Khondaker Miraz Rahman, Julian A. Hiscox, Miles W. Carroll	2025	1
2	Using minor variant genomes and machine learning to study the genome biology of SARS-CoV-2 over time Nucleic Acids Research ·Xiaofeng Dong, David A. Matthews, Giulia Gallo, Alistair C. Darby, I’ah Donovan-Banfield, Hannah Goldswain, Tracy MacGill, Todd Myers, Robert D. Orr, Dalan Bailey, Miles W. Carroll, Julian A. Hiscox	2025	1
3	Discontinuous EBOV RNA synthesis events in patients with Ebola virus disease and their relationship to viral load and outcome of infection Journal of Virology ·Xiaofeng Dong, Isabel García-Dorival, Natasha Y. Rickett, Andrew Bosworth, Sophie J. Smither, Stuart Dowall, Miles W. Carroll, David A. Matthews, Thomas R. Laws, Paul Digard, Julian A. Hiscox	2025	0
4	Hypoxia inducible factors inhibit respiratory syncytial virus infection by modulation of nucleolin expression iScience ·Xiaodong Zhuang, Giulia Gallo, Parul Sharma, Jiyeon Ha, Andrea Magrì, Helene Borrmann, James Michael Harris, Senko Tsukuda, Eleanor G. Bentley, Adam Kirby, Simon De Neck, Hongbing Yang, Peter Balfe, Peter A. C. Wing, David A. Matthews, Adrian L. Harris, Anja Kipar, James P. Stewart, Dalan Bailey, Jane A. McKeating	2023	8
5	Voluntary risk mitigation behaviour can reduce impact of SARS-CoV-2: a real-time modelling study of the January 2022 Omicron wave in England BMC Medicine ·Ellen Brooks‐Pollock, Kate Northstone, Lorenzo Pellis, Francesca Scarabel, Amy Thomas, Emily Nixon, David A. Matthews, Vicky Bowyer, María Paz García, Claire J. Steves, Nicholas J. Timpson, León Danon	2023	2
6	Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2 Nature Communications ·Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K. Shoemark, A. Sofia F. Oliveira, David A. Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K.N. Yadav, Ufuk Borucu, Frédéric Garzoni, Daniel J. Fitzgerald, Joachim P. Spatz, Adrian J. Mulholland, Andrew D. Davidson, Christiane Schaffitzel, Imre Berger	2022	17
7	TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction PLoS Pathogens ·Hataf Khan, Helena Winstone, Jose M. Jiménez-Guardeño, Carl Graham, Katie J. Doores, Caroline Goujon, David A. Matthews, Andrew D. Davidson, Suzannah J. Rihn, Massimo Palmarini, Stuart J. D. Neil, Michael H. Malim	2021	20
8	SARS-CoV-2 vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals low levels of viral backbone gene transcription alongside very high levels of SARS-CoV-2 S glycoprotein gene transcription Genome Medicine ·Abdulaziz Almuqrin, Andrew D. Davidson, Maia Kavanagh Williamson, Philip A. Lewis, Kate J. Heesom, Susan Morris, Sarah C. Gilbert, David A. Matthews	2021	39
9	Zika Virus Infection Preferentially Counterbalances Human Peripheral Monocyte and/or NK Cell Activity mSphere ·Fok‐Moon Lum, David Lee, Tze‐Kwang Chua, Jeslin J. L. Tan, Cheryl Yi‐Pin Lee, Xuan Liu, Yongxiang Fang, Bernett Lee, Wearn‐Xin Yee, Natasha Y. Rickett, Po Ying Chia, Vanessa Lim, Yee‐Sin Leo, David A. Matthews, Julian A. Hiscox, Lisa F. P. Ng	2018	30
10	Proteomics informed by transcriptomics for characterising differential cellular susceptibility to Nelson Bay orthoreovirus infection BMC Genomics ·Lawrence Mok, James W. Wynne, Mary Tachedjian, Brian J. Shiell, Kris Ford, David A. Matthews, Antony Bacic, Wojtek P. Michalski	2017	6
11	Molecular characterisation of ‘strangles’ outbreaks in the UK: The use of M‐protein typing of Streptococcus equi ssp. equi Equine Veterinary Journal ·Philip Ivens, David A. Matthews, K. Webb, J. R. Newton, Karen F. Steward, Andrew S. Waller, Carl Robinson, Josh Slater	2010	35
12	Comparison between the interactions of adenovirus-derived peptides with plasmid DNA and their role in gene delivery mediated by liposome–peptide–DNA virus-like nanoparticles Organic & Biomolecular Chemistry ·Monika Preuss, Miriam Tecle, Syed Imran Ali Shah, David A. Matthews, Andrew D. Miller	2003	13
13	Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids Bioorganic & Medicinal Chemistry Letters ·Peter S. Dragovich, Stephen E. Webber, Thomas J. Prins, Ru Zhou, Joseph Marakovits, Jayashree Tikhe, Shella A. Fuhrman, Amy K. Patick, David A. Matthews, Clifford E. Ford, Edward L. Brown, Susan L. Binford, James W. Meador, Rose Ann Ferre, Stephen T. Worland	1999	18
14	The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation The EMBO Journal ·Svend K. Petersen‐Mahrt, Camilla Estmer, Christina Öhrmalm, David A. Matthews, W. C. Russell, Göran Akusjärvi	1999	138
15	Adenovirus core protein V is delivered by the invading virus to the nucleus of the infected cell and later in infection is associated with nucleoli. Journal of General Virology ·David A. Matthews, W. C. Russell	1998	71
16	Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein Cell ·David A. Matthews, Ward W. Smith, Rose Ann Ferre, Brad Condon, Gregg Budahazi, Wes Slsson, J. Ernest Villafranca, Cheryl A. Janson, H.E. McElroy, Cindy L. Gribskov, Stephen T. Worland	1994	285
17	Structure of and kinetic channelling in bifunctional dihydrofolate reductase–thymidylate synthase Nature Structural Biology ·Daniel R. Knighton, Chen‐Chen Kan, Eleanor F. Howland, Cheryl A. Janson, Zuzana Hostomska, Katherine M. Welsh, David A. Matthews	1994	169
18	11 Ribonucleases H Cold Spring Harbor Monograph Archive ·Zdeněk Hostomský, Zuzana Hostomska, David A. Matthews	1993	4
19	Analysis of relatedness of subgroup A respiratory syncytial viruses isolated worldwide Virus Research ·Patricia A. Cane, David A. Matthews, C. R. Pringle	1992	52
20	Stereochemical mechanism of action for thymidylate synthase based on the X-ray structure of the covalent inhibitory ternary complex with 5-fluoro-2′-deoxyuridylate and 5,10-methylenetetrahydrofolate Journal of Molecular Biology ·David A. Matthews, J. Ernest Villafranca, Cheryl A. Janson, Ward W. Smith, Katherine M. Welsh, S. Freer	1990	99

About David A. Matthews

David A. Matthews is a scholar working on Infectious Diseases, Virology, Genetics, Molecular Biology and Animal Science and Zoology, having authored 139 papers that have together received 8.8k indexed citations. Recurring topics across this work include Virus-based gene therapy research (30 papers), RNA and protein synthesis mechanisms (19 papers), Enzyme Structure and Function (19 papers), Viral gastroenteritis research and epidemiology (18 papers), Biochemical and Molecular Research (17 papers), Respiratory viral infections research (17 papers), Viral Infections and Immunology Research (14 papers) and Viral Infections and Vectors (12 papers). The work is most often cited by research in Infectious Diseases (2.7k citations), Virology (418 citations), Molecular Biology (4.8k citations), Animal Science and Zoology (515 citations) and Epidemiology (1.6k citations). David A. Matthews has collaborated with scholars based in United Kingdom, United States and Singapore. Frequent co-authors include J. Kraut, J.T. Bolin, David J. Filman, W. C. Russell, R. Hamlin, Zuzana Hostomska, Richard A. Alden, C. R. Pringle, Patricia A. Cane and Zdeněk Hostomský. Their work appears in journals such as Journal of General Virology, Journal of Biological Chemistry, Journal of Virology, Journal of Medicinal Chemistry and Bioorganic & Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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