Zdeněk Hostomský

5.8k citations

53 papers · 4.3k indexed · h-index 31

Impact in

Virology top 1%
- HIV Research and Treatment
Oncology top 2%
- PARP inhibition in cancer therapy

Papers in

Virology 12
- HIV Research and Treatment 12
Infectious Diseases 14
- HIV/AIDS drug development and treatment 14

Co-authors: Zuzana Hostomska Nicola J. Curtin Jay F. Davies David A. Matthews Suzanne Kyle Steven R. Jordan David R. Newell Ellen W. Moomaw
Journals: Clinical Cancer Research (4 papers)Gene (4 papers)Journal of Virology (4 papers)Journal of Medicinal Chemistry (3 papers)Biochemistry (3 papers)
Partner nations: United States United Kingdom Czechia

In The Last Decade

Zdeněk Hostomský

53 papers receiving 4.1k citations

Peers

Countries citing papers authored by Zdeněk Hostomský

Since Specialization

Citations

This map shows the geographic impact of Zdeněk Hostomský's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Zdeněk Hostomský with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Zdeněk Hostomský more than expected).

Fields of papers citing papers by Zdeněk Hostomský

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Zdeněk Hostomský. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Zdeněk Hostomský. The network helps show where Zdeněk Hostomský may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Zdeněk Hostomský, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Zdeněk Hostomský Line = papers co-authored together Zdeněk Hostomský links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Tumour cell retention of rucaparib, sustained PARP inhibition and efficacy of weekly as well as daily schedules British Journal of Cancer ·J. C. Murray, Huw D. Thomas, P. Berry, Suzanne Kyle, Miranda Patterson, Christopher J. Jones, Gerrit Los, Zdeněk Hostomský, Elizabeth Ruth Plummer, Alan V. Boddy, Nicola J. Curtin	2014	33
2	NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699 Oncogene ·Jill V. Hunter, Elaine Willmore, Julie Irving, Zdeněk Hostomský, Stephany Veuger, Barbara W. Durkacz	2011	34
3	Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors Clinical Cancer Research ·Asima Mukhopadhyay, Ahmed Elattar, 鍾世忠, Sarah Wilkinson, Yvette Drew, Suzanne Kyle, Gerrit Los, Zdeněk Hostomský, Richard J. Edmondson, Nicola J. Curtin	2010	207
4	Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma Clinical Cancer Research ·Johanna Ohayon, Agata Rozanska, Huw D. Thomas, Evan A. Mulligan, Yvette Drew, Deborah J. Castelbuono, Zdeněk Hostomský, Elizabeth Ruth Plummer, Alan V. Boddy, Deborah A. Tweddle, Nicola J. Curtin, Steven C. Clifford	2009	61
5	Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial Molecular Cancer Therapeutics ·Huw D. Thomas, Christopher Calabrese, Michael A. Batey, Stacie Canan, Zdeněk Hostomský, Suzanne Kyle, Karen A. Maegley, David R. Newell, Donald J. Skalitzky, Lan-Zhen Wang, Stephen E. Webber, Nicola J. Curtin	2007	233
6	Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Alex W. White, Nicola J. Curtin, Brian Eastman, Bernard T. Golding, Zdeněk Hostomský, Suzanne Kyle, Jianke Li, Karen A. Maegley, Donald J. Skalitzky, Stephen E. Webber, Xiaohong Yu, Roger J. Griffin	2004	60
7	Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 Inhibitors Journal of Medicinal Chemistry ·Donald J. Skalitzky, Joseph Marakovits, Karen A. Maegley, Anne Ekker, Xiaohong Yu, Zdeněk Hostomský, Stephen E. Webber, Brian Eastman, Robert J. Almassy, Jianke Li, Nicola J. Curtin, David R. Newell, A. Hilary Calvert, Roger J. Griffin, Bernard T. Golding	2002	126
8	Design and evaluation of novel potent inhibitors of poly (ADP-ribose) polymerase Clinical Cancer Research ·P. Lautenschlaeger, Nicola J. Curtin, Daniel Tria Pramono, Talitha Mirja de Vries, Umar Manzoor Shah, Suzanne Kyle, M.V. Astashkinа, Teerawan Suwan, Jarl Robert Pedersen, Robert Griffin, B.T. Golding, Zdeněk Hostomský, A H Calvert, Newell	2000	1
9	Development of a Nonradioactive Ribonuclease H Assay Analytical Biochemistry ·Sang Yu-l, Zuzana Hostomska, Zdeněk Hostomský, P. Štrop	1996	9
10	A Specific RNA Structural Motif Mediates High Affinity Binding by the HIV-1 Nucleocapsid Protein (NCp7) Virology ·Patrick Allen, Brian D. Collins, David Brown, Zdeněk Hostomský, Larry Gold	1996	33
11	Restriction of HIV-1 Replication in Intestinal Cells Is Genetically Controlled by the gag-pol Region of the HIV-1 Genome Virology ·안대섭, Marta Banjac, Gautham Gopan, Danièle Salaün, Yee-Huang Ku, Zdeněk Hostomský, Ivan Hirsch	1995	6
12	Comprehensive Chemical Modification Interference and Nucleotide Substitution Analysis of an RNA Pseudoknot Inhibitor to HIV-1 Reverse Transcrip tase Journal of Molecular Biology ·Louis Green, Sheela Waugh, Jonathan Binkley, Zuzana Hostomska, Zdeněk Hostomský, Craig Tuerk	1995	45
13	Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates Current Opinion in Structural Biology ·Eddy Arnold, Wanyama Chituwo, Stephen H. Hughes, Zdeněk Hostomský	1995	60
14	Structure-function analysis of the mammalian DNA polymerase .beta. active site: role of aspartic acid 256, arginine 254, and arginine 258 in nucleotidyl transfer Biochemistry ·Karen Shaines, Zdeněk Hostomský, B R Nodes, 村岡秀明, Esteban Cuartas, Ellen W. Moomaw, Robert J. Almassy, Zuzana Hostomska	1995	61
15	High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus Biochemistry ·Daniel J. Schneider, Juli Feigon, Zdeněk Hostomský, Larry Gold	1995	135
16	2.3 Å crystal structure of the catalytic domain of DNA polymerase β Cell ·Jay F. Davies, Robert J. Almassy, Zuzana Hostomska, Rose Ann Ferre, Zdeněk Hostomský	1994	152
17	11 Ribonucleases H Cold Spring Harbor Monograph Archive ·Zdeněk Hostomský, Zuzana Hostomska, David A. Matthews	1993	4
18	RNase D, a reported new activity associated with HIV-1 reverse transcriptase, displays the same cleavage specificity asEscherichia coliRNase III Nucleic Acids Research ·Zdeněk Hostomský, 村岡秀明, Esteban Cuartas, Zuzana Hostomska	1992	13
19	High-level expression of self-processed HIV-1 protease in Escherichia coli using a synthetic gene Biochemical and Biophysical Research Communications ·Zdeněk Hostomský, Krzysztof Appelt, Richard C. Ogden	1989	40
20	Solid-phase assembly of cow colostrum trypsin inhibitor gene Nucleic Acids Research ·Zdeněk Hostomský, J. Smrt, Adrielly Jordane Lourencetti, Xia Hai‐Bo, Václav Pačes	1987	27

About Zdeněk Hostomský

Zdeněk Hostomský is a scholar working on Virology, Infectious Diseases, Molecular Biology, Oncology and Hepatology, having authored 53 papers that have together received 4.3k indexed citations. Recurring topics across this work include PARP inhibition in cancer therapy (16 papers), DNA Repair Mechanisms (15 papers), HIV/AIDS drug development and treatment (14 papers), HIV Research and Treatment (12 papers), RNA and protein synthesis mechanisms (12 papers), DNA and Nucleic Acid Chemistry (11 papers), Bacteriophages and microbial interactions (9 papers) and Bacterial Genetics and Biotechnology (7 papers). The work is most often cited by research in Virology (659 citations), Oncology (1.6k citations), Hepatology (412 citations), Infectious Diseases (867 citations) and Molecular Biology (2.7k citations). Zdeněk Hostomský has collaborated with scholars based in United States, United Kingdom and Czechia. Frequent co-authors include Zuzana Hostomska, Nicola J. Curtin, Jay F. Davies, David A. Matthews, Suzanne Kyle, Steven R. Jordan, David R. Newell, Ellen W. Moomaw, Robert J. Almassy and Josiane Ménissier‐de Murcia. Their work appears in journals such as Clinical Cancer Research, Gene, Journal of Virology, Journal of Medicinal Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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