Raffaele De Francesco

17.1k total citations · 2 hit papers
155 papers, 12.2k citations indexed

About

Raffaele De Francesco is a scholar working on Hepatology, Epidemiology and Molecular Biology. According to data from OpenAlex, Raffaele De Francesco has authored 155 papers receiving a total of 12.2k indexed citations (citations by other indexed papers that have themselves been cited), including 104 papers in Hepatology, 65 papers in Epidemiology and 62 papers in Molecular Biology. Recurrent topics in Raffaele De Francesco's work include Hepatitis C virus research (103 papers), Hepatitis B Virus Studies (54 papers) and Monoclonal and Polyclonal Antibodies Research (38 papers). Raffaele De Francesco is often cited by papers focused on Hepatitis C virus research (103 papers), Hepatitis B Virus Studies (54 papers) and Monoclonal and Polyclonal Antibodies Research (38 papers). Raffaele De Francesco collaborates with scholars based in Italy, United States and Germany. Raffaele De Francesco's co-authors include Licia Tomei, Christian Steinkühler, Giovanni Migliaccio, Cristina Maria Failla, Petra Neddermann, Sergio Altamura, Paola Gallinari, Sven‐Erik Behrens, Andrea Carfı́ and Mirko Brunetti and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Raffaele De Francesco

154 papers receiving 11.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus.

1996 569 citations Sven‐Erik Behrens, Licia Tomei et al. profile →
Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

2004 526 citations Alessandro Vannini, Cinzia Volpari et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Raffaele De Francesco Italy	63	6.4k	5.1k	4.3k	2.7k	1.8k	155	12.2k
Timothy M. Block United States	63	4.0k 0.6×	4.4k 0.9×	6.3k 1.5×	1.9k 0.7×	479 0.3×	232	12.6k
Michael M. C. Lai United States	65	4.2k 0.7×	3.5k 0.7×	4.1k 1.0×	3.8k 1.4×	561 0.3×	174	12.2k
Volker Lohmann Germany	62	10.2k 1.6×	3.3k 0.7×	7.8k 1.8×	2.2k 0.8×	1.3k 0.8×	129	13.7k
Michinori Kohara Japan	56	5.2k 0.8×	3.9k 0.8×	4.9k 1.1×	2.1k 0.8×	732 0.4×	263	11.3k
Kunitada Shimotohno Japan	74	10.4k 1.6×	7.8k 1.5×	8.5k 2.0×	1.9k 0.7×	1.9k 1.1×	355	21.8k
Riccardo Cortese Italy	60	2.7k 0.4×	5.7k 1.1×	2.9k 0.7×	960 0.4×	2.0k 1.1×	144	11.1k
Darius Moradpour Switzerland	61	10.4k 1.6×	3.6k 0.7×	7.4k 1.7×	2.4k 0.9×	1.1k 0.6×	273	15.4k
Thomas F. Baumert France	65	8.4k 1.3×	3.2k 0.6×	7.9k 1.9×	1.3k 0.5×	1.6k 0.9×	273	13.9k
Ann D. Kwong United States	37	3.6k 0.6×	1.9k 0.4×	3.8k 0.9×	1.9k 0.7×	479 0.3×	70	6.6k
Tetsuro Suzuki Japan	48	3.5k 0.5×	3.2k 0.6×	3.2k 0.8×	1.1k 0.4×	592 0.3×	233	8.5k

Countries citing papers authored by Raffaele De Francesco

Since Specialization

Citations

This map shows the geographic impact of Raffaele De Francesco's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Raffaele De Francesco with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Raffaele De Francesco more than expected).

Fields of papers citing papers by Raffaele De Francesco

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Raffaele De Francesco. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Raffaele De Francesco. The network helps show where Raffaele De Francesco may publish in the future.

Co-authorship network of co-authors of Raffaele De Francesco

This figure shows the co-authorship network connecting the top 25 collaborators of Raffaele De Francesco. A scholar is included among the top collaborators of Raffaele De Francesco based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Raffaele De Francesco. Raffaele De Francesco is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Santambrogio, Carlo, Lorena Donnici, Elisa Pesce, et al.. (2025). Biomimetic Recognition of SARS‐CoV‐2 Receptor‐Binding Domain N‐Glycans by an Antiviral Synthetic Receptor. ChemBioChem. 26(7). e202500106–e202500106. 1 indexed citations

Francesco, Raffaele De, et al.. (2024). Comparison of different guidance strategies to percutaneous coronary intervention: A network meta-analysis of randomized clinical trials. International Journal of Cardiology. 422. 132936–132936.

Colciago, Alessandra, Alessandra Fasciani, Raffaele De Francesco, et al.. (2024). Typical NF2 and LTZR1 mutations are retained in an immortalized human schwann cell model of schwannomatosis. Heliyon. 10(19). e38957–e38957. 1 indexed citations

Andreano, Emanuele, Ida Paciello, Lorena Donnici, et al.. (2022). Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees. Nature Communications. 13(1). 3375–3375. 15 indexed citations

Lovell, William, Daisuke Yamane, Petra Neddermann, et al.. (2017). NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains. PLoS Pathogens. 13(6). e1006343–e1006343. 15 indexed citations

Ranzani, Valeria, Grazisa Rossetti, Ilaria Panzeri, et al.. (2015). The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nature Immunology. 16(3). 318–325. 268 indexed citations

Nicola, Stella De, Alessio Aghemo, Maria Grazia Rumi, et al.. (2011). Interleukin 28B Polymorphism Predicts Pegylated Interferon Plus Ribavirin Treatment Outcome in Chronic Hepatitis C Genotype 4. Hepatology. 55(2). 336–342. 67 indexed citations

Cadot, Bruno, Mirko Brunetti, Sabina Coppari, et al.. (2009). Loss of Histone Deacetylase 4 Causes Segregation Defects during Mitosis of p53-Deficient Human Tumor Cells. Cancer Research. 69(15). 6074–6082. 37 indexed citations

Lahm, Armin, Chantal Paolini, Michele Pallaoro, et al.. (2007). Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases. Proceedings of the National Academy of Sciences. 104(44). 17335–17340. 443 indexed citations

10.

Neddermann, Petra, Manuela Quintavalle, Chiara Di Pietro, et al.. (2004). Reduction of Hepatitis C Virus NS5A Hyperphosphorylation by Selective Inhibition of Cellular Kinases Activates Viral RNA Replication in Cell Culture. Journal of Virology. 78(23). 13306–13314. 108 indexed citations

11.

Vannini, Alessandro, Cinzia Volpari, Gessica Filocamo, et al.. (2004). Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor. Proceedings of the National Academy of Sciences. 101(42). 15064–15069. 526 indexed citations breakdown →

12.

Summa, Vincenzo, Alessia Petrocchi, Victor G. Matassa, et al.. (2004). HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis. Journal of Medicinal Chemistry. 47(22). 5336–5339. 74 indexed citations

13.

Cicero, Daniel O., Gaetano Barbato, Uwe Koch, et al.. (2001). Measurement of homonuclear three-bond J(HNHα) coupling constants in unlabeled peptides complexed with labeled proteins: Application to a decapeptide inhibitor bound to the proteinase domain of the NS3 protein of hepatitis C virus (HCV). Journal of Biomolecular NMR. 20(1). 23–29. 1 indexed citations

14.

Marco, Stefania Di, Menico Rizzi, Cinzia Volpari, et al.. (2000). Inhibition of the Hepatitis C Virus NS3/4A Protease. Journal of Biological Chemistry. 275(10). 7152–7157. 107 indexed citations

15.

Fattori, Daniela, Andrea Urbani, Mirko Brunetti, et al.. (2000). Probing the Active Site of the Hepatitis C Virus Serine Protease by Fluorescence Resonance Energy Transfer. Journal of Biological Chemistry. 275(20). 15106–15113. 18 indexed citations

16.

Cicero, Daniel O., Gaetano Barbato, Uwe Koch, et al.. (1999). Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies. Journal of Molecular Biology. 289(2). 385–396. 48 indexed citations

17.

Pasquo, Alessandra, Maria Chiara Nardi, Nazzareno Dimasi, et al.. (1998). Rational design and functional expression of a constitutively active single-chain NS4A–NS3 proteinase. PubMed. 3(6). 433–441. 11 indexed citations

18.

Yan, Youwei, Ying Li, Sanjeev Munshi, et al.. (1998). Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form. Protein Science. 7(4). 837–847. 202 indexed citations

19.

Francesco, Raffaele De, Sven‐Erik Behrens, Licia Tomei, Sergio Altamura, & Josef Jiricny. (1996). [4] RNA-dependent RNA polymerase of hepatitis C virus. Methods in enzymology on CD-ROM/Methods in enzymology. 275. 58–67. 68 indexed citations

20.

Steinkühler, Christian, Andrea Urbani, Licia Tomei, et al.. (1996). Activity of purified hepatitis C virus protease NS3 on peptide substrates. Journal of Virology. 70(10). 6694–6700. 123 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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