David A. Fruman

2.7k total citations · 1 hit paper
13 papers, 2.2k citations indexed

About

David A. Fruman is a scholar working on Molecular Biology, Immunology and Oncology. According to data from OpenAlex, David A. Fruman has authored 13 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 6 papers in Immunology and 4 papers in Oncology. Recurrent topics in David A. Fruman's work include T-cell and B-cell Immunology (4 papers), PI3K/AKT/mTOR signaling in cancer (3 papers) and Protein Kinase Regulation and GTPase Signaling (3 papers). David A. Fruman is often cited by papers focused on T-cell and B-cell Immunology (4 papers), PI3K/AKT/mTOR signaling in cancer (3 papers) and Protein Kinase Regulation and GTPase Signaling (3 papers). David A. Fruman collaborates with scholars based in United States, Switzerland and Japan. David A. Fruman's co-authors include Lewis C. Cantley, Rachel Meyers, Owen N. Witte, Anne B. Satterthwaite, Lucia E. Rameh, Christopher L. Carpenter, Amber C. Donahue, Roderick T. Bronson, Derek P. Brazil and Claudine M. Yballe and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

David A. Fruman

13 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PHOSPHOINOSITIDE KINASES

1998 1.2k citations David A. Fruman, Rachel Meyers et al. Annual Review of Biochemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David A. Fruman United States	13	1.5k	540	409	346	263	13	2.2k
Roy Katso United Kingdom	13	1.9k 1.2×	375 0.7×	466 1.1×	409 1.2×	298 1.1×	15	2.6k
Evan Ingley Australia	25	1.5k 1.0×	436 0.8×	339 0.8×	368 1.1×	216 0.8×	66	2.3k
Maria-Magdalena Georgescu United States	17	1.8k 1.1×	495 0.9×	339 0.8×	339 1.0×	296 1.1×	29	2.5k
Ornella Azzolino Italy	13	1.1k 0.8×	714 1.3×	234 0.6×	357 1.0×	232 0.9×	13	2.0k
Paul J. Coffer Netherlands	18	1.4k 0.9×	452 0.8×	232 0.6×	353 1.0×	145 0.6×	27	2.1k
C M Heyworth United Kingdom	24	1.5k 1.0×	711 1.3×	274 0.7×	368 1.1×	265 1.0×	58	2.5k
Kathrin H. Kirsch United States	24	1.5k 1.0×	410 0.8×	326 0.8×	364 1.1×	173 0.7×	44	2.2k
Rebecca J. Chan United States	32	2.2k 1.5×	917 1.7×	299 0.7×	531 1.5×	349 1.3×	90	3.3k
Karen O. Yee United States	16	1.9k 1.2×	403 0.7×	655 1.6×	414 1.2×	109 0.4×	23	2.6k
Joseph P. Gardner United States	6	1.2k 0.8×	616 1.1×	293 0.7×	483 1.4×	92 0.3×	8	2.1k

Countries citing papers authored by David A. Fruman

Since Specialization

Citations

This map shows the geographic impact of David A. Fruman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David A. Fruman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David A. Fruman more than expected).

Fields of papers citing papers by David A. Fruman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David A. Fruman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David A. Fruman. The network helps show where David A. Fruman may publish in the future.

Co-authorship network of co-authors of David A. Fruman

This figure shows the co-authorship network connecting the top 25 collaborators of David A. Fruman. A scholar is included among the top collaborators of David A. Fruman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David A. Fruman. David A. Fruman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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13 of 13 papers shown

Mancini, Maria, Tatiana V. Petrova, Lucy Liaw, et al.. (2009). Organ‐specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene‐targeting of the PI3K regulatory isoforms p85α, p55α, and p50α. Developmental Dynamics. 238(10). 2670–2679. 48 indexed citations

Donahue, Amber C. & David A. Fruman. (2007). Distinct signaling mechanisms activate the target of rapamycin in response to different B‐cell stimuli. European Journal of Immunology. 37(10). 2923–2936. 62 indexed citations

Oak, Jean, Jonathan A. Deane, Michael G. Kharas, et al.. (2006). Sjögren's syndrome-like disease in mice with T cells lacking class 1A phosphoinositide-3-kinase. Proceedings of the National Academy of Sciences. 103(45). 16882–16887. 54 indexed citations

Deane, Jonathan A., Michael G. Kharas, Jean Oak, et al.. (2006). T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. Blood. 109(7). 2894–2902. 50 indexed citations

Trümper, K, Heidi Trusheim, Kohjiro Ueki, et al.. (2003). Altered Signaling and Cell Cycle Regulation in Embryonal Stem Cells with a Disruption of the Gene for Phosphoinositide 3-Kinase Regulatory Subunit p85α. Journal of Biological Chemistry. 278(7). 5099–5108. 34 indexed citations

Kurnasov, Oleg V., Anna Usacheva, Brian A. Hemmings, et al.. (2001). Phosphatidylinositol 3-Kinase Confers Resistance to Encephalomyocarditis and Herpes Simplex Virus-Induced Cell Death Through the Activation of Distinct Downstream Effectors. The Journal of Immunology. 167(8). 4553–4559. 23 indexed citations

Fruman, David A., Daniel A. Pollard, Claudine M. Yballe, et al.. (2000). Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85α. Nature Genetics. 26(3). 379–382. 240 indexed citations

Fruman, David A., Anne B. Satterthwaite, & Owen N. Witte. (2000). Xid-like Phenotypes. Immunity. 13(1). 1–3. 166 indexed citations

Lu-Kuo, Jennifer M., et al.. (2000). Impaired Kit- but Not FcεRI-initiated Mast Cell Activation in the Absence of Phosphoinositide 3-Kinase p85α Gene Products. Journal of Biological Chemistry. 275(8). 6022–6029. 71 indexed citations

10.

Nishikawa, Kiyotaka, Sansana Sawasdikosol, David A. Fruman, et al.. (2000). A Peptide Library Approach Identifies a Specific Inhibitor for the ZAP-70 Protein Tyrosine Kinase. Molecular Cell. 6(4). 969–974. 28 indexed citations

11.

Fruman, David A., Lucia E. Rameh, & Lewis C. Cantley. (1999). Phosphoinositide Binding Domains. Cell. 97(7). 817–820. 106 indexed citations

12.

Fruman, David A., Rachel Meyers, & Lewis C. Cantley. (1998). PHOSPHOINOSITIDE KINASES. Annual Review of Biochemistry. 67(1). 481–507. 1199 indexed citations breakdown →

13.

Fruman, David A., Lewis C. Cantley, & Christopher L. Carpenter. (1996). Structural Organization and Alternative Splicing of the Murine Phosphoinositide 3-Kinase p85α Gene. Genomics. 37(1). 113–121. 101 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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