Ann–Hwee Lee

18.7k total citations · 8 hit papers
50 papers, 14.4k citations indexed

About

Ann–Hwee Lee is a scholar working on Cell Biology, Molecular Biology and Epidemiology. According to data from OpenAlex, Ann–Hwee Lee has authored 50 papers receiving a total of 14.4k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Cell Biology, 20 papers in Molecular Biology and 18 papers in Epidemiology. Recurrent topics in Ann–Hwee Lee's work include Endoplasmic Reticulum Stress and Disease (35 papers), Lipid metabolism and biosynthesis (12 papers) and Pancreatic function and diabetes (11 papers). Ann–Hwee Lee is often cited by papers focused on Endoplasmic Reticulum Stress and Disease (35 papers), Lipid metabolism and biosynthesis (12 papers) and Pancreatic function and diabetes (11 papers). Ann–Hwee Lee collaborates with scholars based in United States, South Korea and Japan. Ann–Hwee Lee's co-authors include Laurie H. Glimcher, Neal N. Iwakoshi, Gökhan S. Hotamışlıgil, Gürol Tuncman, Umut Özcan, Cem Z. Görgün, Qiong Cao, Erkan Yılmaz, Xi Chen and David E. Cohen and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ann–Hwee Lee

50 papers receiving 14.3k citations

Hit Papers

Endoplasmic Reticulum Stress Links Obesity, Insulin Actio... 2003 2026 2010 2018 2004 2003 2008 2004 2010 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes
    2004 3.0k citations Umut Özcan, Qiong Cao et al. Science profile →
  2. XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response
    2003 1.7k citations Ann–Hwee Lee, Neal N. Iwakoshi et al. profile →
  3. XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
    2008 1.1k citations Ann–Hwee Lee, Laurie H. Glimcher et al. Cell profile →
  4. XBP1, Downstream of Blimp-1, Expands the Secretory Apparatus and Other Organelles, and Increases Protein Synthesis in Plasma Cell Differentiation
    2004 793 citations Arthur L. Shaffer, Miriam A. Shelef et al. Immunity profile →
  5. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
    2010 787 citations Fabio Martinon, Xi Chen et al. Nature Immunology profile →
  6. Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1
    2008 775 citations Ann–Hwee Lee, Laurie H. Glimcher et al. Science profile →
  7. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
    2003 700 citations Neal N. Iwakoshi, Ann–Hwee Lee et al. Nature Immunology profile →
  8. ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
    2015 684 citations Juan R. Cubillos‐Ruiz, Pedro C. Silberman et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Ann–Hwee Lee United States 36 8.1k 5.6k 5.3k 2.9k 2.9k 50 14.4k
Seiichi Oyadomari Japan 38 7.0k 0.9× 5.9k 1.1× 4.2k 0.8× 2.8k 0.9× 1.1k 0.4× 90 12.6k
Fumihiko Urano United States 50 9.3k 1.1× 7.3k 1.3× 5.1k 1.0× 3.5k 1.2× 1.3k 0.5× 122 15.6k
Neal N. Iwakoshi United States 31 5.4k 0.7× 3.6k 0.6× 3.4k 0.6× 2.3k 0.8× 2.6k 0.9× 47 10.3k
Kazutoshi Mori Japan 64 17.7k 2.2× 12.3k 2.2× 8.4k 1.6× 3.4k 1.2× 2.5k 0.9× 151 23.3k
Hiderou Yoshida Japan 39 12.4k 1.5× 7.9k 1.4× 5.8k 1.1× 2.3k 0.8× 1.6k 0.5× 67 15.5k
Donalyn Scheuner United States 34 6.0k 0.7× 6.0k 1.1× 3.3k 0.6× 2.2k 0.7× 1.2k 0.4× 49 11.0k
Tomomi Gotoh Japan 46 3.9k 0.5× 4.1k 0.7× 2.2k 0.4× 1.8k 0.6× 1.3k 0.4× 95 9.5k
Joungmok Kim South Korea 27 4.2k 0.5× 8.7k 1.5× 6.7k 1.3× 1.2k 0.4× 975 0.3× 50 15.2k
Takashi Ueno Japan 52 4.8k 0.6× 8.7k 1.5× 13.1k 2.5× 1.3k 0.4× 1.3k 0.4× 128 19.5k
Tomoichiro Asano Japan 69 2.4k 0.3× 10.3k 1.8× 3.0k 0.6× 4.1k 1.4× 1.7k 0.6× 313 17.8k

Countries citing papers authored by Ann–Hwee Lee

Since Specialization
Citations

This map shows the geographic impact of Ann–Hwee Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ann–Hwee Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ann–Hwee Lee more than expected).

Fields of papers citing papers by Ann–Hwee Lee

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ann–Hwee Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ann–Hwee Lee. The network helps show where Ann–Hwee Lee may publish in the future.

Co-authorship network of co-authors of Ann–Hwee Lee

This figure shows the co-authorship network connecting the top 25 collaborators of Ann–Hwee Lee. A scholar is included among the top collaborators of Ann–Hwee Lee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ann–Hwee Lee. Ann–Hwee Lee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Glimcher, Laurie H., Ann–Hwee Lee, & Neal N. Iwakoshi. (2020). XBP-1 and the unfolded protein response (UPR). Nature Immunology. 21(9). 963–965. 28 indexed citations
2.
Sans, A, Stéphanie Bonnafous, Déborah Rousseau, et al.. (2019). The Differential Expression of Cide Family Members is Associated with Nafld Progression from Steatosis to Steatohepatitis. Scientific Reports. 9(1). 7501–7501. 35 indexed citations
3.
Fink, Emily E., Sudha Moparthy, Archis Bagati, et al.. (2018). XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response. Cell Reports. 25(1). 212–223.e4. 41 indexed citations
4.
Cubillos‐Ruiz, Juan R., Pedro C. Silberman, Melanie R. Rutkowski, et al.. (2015). ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis. Cell. 161(7). 1527–1538. 684 indexed citations breakdown →
5.
Xu, Xu, Jong‐Gil Park, Jae‐Seon So, Kyu Yeon Hur, & Ann–Hwee Lee. (2014). Transcriptional regulation of apolipoprotein A-IV by the transcription factor CREBH. Journal of Lipid Research. 55(5). 850–859. 41 indexed citations
6.
Lee, Ann–Hwee. (2012). The role of CREB-H transcription factor in triglyceride metabolism. Current Opinion in Lipidology. 23(2). 141–146. 33 indexed citations
7.
Kwon, Jeongho, Chi‐Bao Bui, Jun Ho Lee, et al.. (2012). Assurance of mitochondrial integrity and mammalian longevity by the p62–Keap1–Nrf2–Nqo1 cascade. EMBO Reports. 13(2). 150–156. 119 indexed citations
8.
So, Jae‐Seon, Kyu Yeon Hur, Margarite L. Tarrio, et al.. (2012). Silencing of Lipid Metabolism Genes through IRE1α-Mediated mRNA Decay Lowers Plasma Lipids in Mice. Cell Metabolism. 16(4). 487–499. 215 indexed citations
9.
Lee, Jung Hoon, Petros Giannikopoulos, Stephen A. Duncan, et al.. (2011). The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism. Nature Medicine. 17(7). 812–815. 165 indexed citations
10.
Hess, David A., Jeff Ishibashi, Barbara Damsz, et al.. (2011). Extensive Pancreas Regeneration Following Acinar-Specific Disruption of Xbp1 in Mice. Gastroenterology. 141(4). 1463–1472. 63 indexed citations
11.
Jurczak, Michael J., Ann–Hwee Lee, François R. Jornayvaz, et al.. (2011). Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice. Journal of Biological Chemistry. 287(4). 2558–2567. 123 indexed citations
12.
Martinon, Fabio, Xi Chen, Ann–Hwee Lee, & Laurie H. Glimcher. (2010). TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nature Immunology. 11(5). 411–418. 787 indexed citations breakdown →
13.
Todd, Derrick J., Louise J. McHeyzer‐Williams, Czeslawa Kowal, et al.. (2009). XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. The Journal of Cell Biology. 186(6). i13–i13. 2 indexed citations
14.
Todd, Derrick J., Louise J. McHeyzer‐Williams, Czeslawa Kowal, et al.. (2009). XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development. The Journal of Experimental Medicine. 206(10). 2151–2159. 170 indexed citations
15.
Todd, Derrick J., Ann–Hwee Lee, & Laurie H. Glimcher. (2008). The endoplasmic reticulum stress response in immunity and autoimmunity. Nature reviews. Immunology. 8(9). 663–674. 484 indexed citations
16.
Lee, Ann–Hwee, Gerald C. Chu, Neal N. Iwakoshi, & Laurie H. Glimcher. (2005). XBP‐1 is required for biogenesis of cellular secretory machinery of exocrine glands. The EMBO Journal. 24(24). 4368–4380. 366 indexed citations
17.
Özcan, Umut, Qiong Cao, Erkan Yılmaz, et al.. (2004). Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes. Science. 306(5695). 457–461. 3035 indexed citations breakdown →
18.
Shaffer, Arthur L., Miriam A. Shelef, Neal N. Iwakoshi, et al.. (2004). XBP1, Downstream of Blimp-1, Expands the Secretory Apparatus and Other Organelles, and Increases Protein Synthesis in Plasma Cell Differentiation. Immunity. 21(1). 81–93. 793 indexed citations breakdown →
19.
Iwakoshi, Neal N., Ann–Hwee Lee, & Laurie H. Glimcher. (2003). The X‐box binding protein‐1 transcription factor is required for plasma cell differentiation and the unfolded protein response. Immunological Reviews. 194(1). 29–38. 209 indexed citations
20.
Lee, Ann–Hwee, Neal N. Iwakoshi, Kenneth C. Anderson, & Laurie H. Glimcher. (2003). Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proceedings of the National Academy of Sciences. 100(17). 9946–9951. 488 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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