Daniela Rotin

16.3k total citations · 4 hit papers
125 papers, 13.0k citations indexed

About

Daniela Rotin is a scholar working on Molecular Biology, Cell Biology and Genetics. According to data from OpenAlex, Daniela Rotin has authored 125 papers receiving a total of 13.0k indexed citations (citations by other indexed papers that have themselves been cited), including 101 papers in Molecular Biology, 28 papers in Cell Biology and 20 papers in Genetics. Recurrent topics in Daniela Rotin's work include Ubiquitin and proteasome pathways (34 papers), Ion Transport and Channel Regulation (25 papers) and Protein Tyrosine Phosphatases (16 papers). Daniela Rotin is often cited by papers focused on Ubiquitin and proteasome pathways (34 papers), Ion Transport and Channel Regulation (25 papers) and Protein Tyrosine Phosphatases (16 papers). Daniela Rotin collaborates with scholars based in Canada, United States and Switzerland. Daniela Rotin's co-authors include Ian F. Tannock, Olivier Staub, Sharad Kumar, Sergio Grinstein, Joseph Schlessinger, Mike J. Mason, Voula Kanelis, Julie D. Forman‐Kay, Andreas Batzer and Pamela Plant and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Daniela Rotin

124 papers receiving 12.8k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Acid pH in tumors and its potential for therapeutic exploitation.

1989 1.4k citations Daniela Rotin et al. profile →
Physiological functions of the HECT family of ubiquitin ligases

2009 830 citations Daniela Rotin, Sharad Kumar Nature Reviews Molecular Cell Biology profile →
WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 697 citations Olivier Staub, Daniela Rotin et al. The EMBO Journal profile →
Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation

1989 666 citations Daniela Rotin et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Daniela Rotin	10.0k	2.1k	1.8k	1.2k	1.2k	125	13.0k
Eileen D. Adamson	8.6k 0.9×	2.1k 1.0×	1.9k 1.1×	887 0.7×	1.8k 1.6×	139	12.6k
Stéphane Angers	10.5k 1.1×	1.9k 0.9×	1.7k 0.9×	2.5k 2.1×	1.2k 1.0×	126	13.2k
Stevan R. Hubbard	9.6k 1.0×	3.7k 1.7×	2.5k 1.4×	899 0.8×	858 0.7×	89	14.4k
Tohru Natsume	11.3k 1.1×	3.9k 1.8×	1.5k 0.8×	636 0.5×	887 0.8×	198	16.3k
G Carpenter	7.1k 0.7×	1.7k 0.8×	3.0k 1.6×	605 0.5×	1.0k 0.9×	58	10.8k
Katsuya Okawa	10.3k 1.0×	3.9k 1.8×	1.4k 0.7×	915 0.8×	1.8k 1.5×	118	15.9k
Alfred Nordheim	13.2k 1.3×	1.7k 0.8×	1.8k 1.0×	1.2k 1.0×	1.8k 1.6×	204	17.7k
James R. Feramisco	12.2k 1.2×	3.5k 1.7×	2.6k 1.4×	1.2k 1.0×	1.8k 1.5×	136	17.0k
Peter W. Gunning	9.4k 0.9×	4.5k 2.1×	1.1k 0.6×	1.4k 1.1×	1.8k 1.5×	240	15.0k
Gordon N. Gill	11.5k 1.1×	3.4k 1.6×	4.0k 2.2×	1.3k 1.1×	1.5k 1.3×	173	17.0k

Countries citing papers authored by Daniela Rotin

Since Specialization

Citations

This map shows the geographic impact of Daniela Rotin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniela Rotin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniela Rotin more than expected).

Fields of papers citing papers by Daniela Rotin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniela Rotin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniela Rotin. The network helps show where Daniela Rotin may publish in the future.

Co-authorship network of co-authors of Daniela Rotin

This figure shows the co-authorship network connecting the top 25 collaborators of Daniela Rotin. A scholar is included among the top collaborators of Daniela Rotin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Daniela Rotin. Daniela Rotin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Persaud, Avinash K., Jing Li, Andrew M. Sydor, et al.. (2025). The primate-specific Nedd4-1(NE) localizes to late endosomes in response to amino acids to suppress autophagy. Nature Communications. 16(1). 2682–2682.

Rotin, Daniela, et al.. (2023). Primate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding. Scientific Reports. 13(1). 17903–17903. 1 indexed citations

Rotin, Daniela & Olivier Staub. (2021). Function and Regulation of the Epithelial Na ⁺ Channel ENaC. Comprehensive physiology. 11(3). 2017–2045. 7 indexed citations

Attali, Ilan, William S. Tobelaim, Avinash K. Persaud, et al.. (2017). Ubiquitylation‐dependent oligomerization regulates activity of Nedd4 ligases. The EMBO Journal. 36(4). 425–440. 40 indexed citations

Zhong, Yunan, et al.. (2016). DrosophilaNedd4-long reduces Amphiphysin levels in muscles and leads to impaired T-tubule formation. Molecular Biology of the Cell. 27(6). 907–918. 4 indexed citations

Lu, Chunhua, Cornelia Thoeni, Ashton A. Connor, et al.. (2016). Intestinal knockout of Nedd4 enhances growth of Apcmin tumors. Oncogene. 35(45). 5839–5849. 25 indexed citations

Murchie, Ryan, Conghui Guo, Avinash K. Persaud, Aleixo M. Muise, & Daniela Rotin. (2014). Protein tyrosine phosphatase σ targets apical junction complex proteins in the intestine and regulates epithelial permeability. Proceedings of the National Academy of Sciences. 111(2). 693–698. 19 indexed citations

Carlile, Graeme W., Renaud Robert, Julie Goepp, et al.. (2014). Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking. Journal of Cystic Fibrosis. 14(1). 16–25. 38 indexed citations

Ramachandran, Shyam, Philip H. Karp, Mark A. Behlke, et al.. (2013). Symposium Session Summaries. Pediatric Pulmonology. 48(S36). 103–206. 1 indexed citations

10.

Chiaw, Patrick Kim, Ling‐Jun Huan, Stéphane Gagnon, et al.. (2009). Functional Rescue of DeltaF508-CFTR by Peptides Designed to Mimic Sorting Motifs. Chemistry & Biology. 16(5). 520–530. 19 indexed citations

11.

Rotin, Daniela & Sharad Kumar. (2009). Physiological functions of the HECT family of ubiquitin ligases. Nature Reviews Molecular Cell Biology. 10(6). 398–409. 830 indexed citations breakdown →

12.

Fouladkou, Fatemeh, Hiroshi Kawabe, Antje Neeb, et al.. (2008). The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Proceedings of the National Academy of Sciences. 105(25). 8585–8590. 145 indexed citations

13.

Muise, Aleixo M. & Daniela Rotin. (2008). Apical junction complex proteins and ulcerative colitis: a focus on the PTPRS gene. Expert Review of Molecular Diagnostics. 8(4). 465–477. 8 indexed citations

14.

Muise, Aleixo M., Thomas D. Walters, Eytan Wine, et al.. (2007). Protein-Tyrosine Phosphatase Sigma Is Associated with Ulcerative Colitis. Current Biology. 17(14). 1212–1218. 50 indexed citations

15.

Lü, Chao, Chong Jiang, Sandra Pribanić, & Daniela Rotin. (2007). CFTR stabilizes ENaC at the plasma membrane. Journal of Cystic Fibrosis. 6(6). 419–422. 7 indexed citations

16.

Kanelis, Voula, M. Christine Bruce, Nikolai R. Skrynnikov, Daniela Rotin, & Julie D. Forman‐Kay. (2006). Structural Determinants for High-Affinity Binding in a Nedd4 WW3∗ Domain-Comm PY Motif Complex. Structure. 14(3). 543–553. 75 indexed citations

17.

Batt, Jane, et al.. (2002). Pituitary, Pancreatic and Gut Neuroendocrine Defects in Protein Tyrosine Phosphatase- Sigma-Deficient Mice. Molecular Endocrinology. 16(1). 155–169. 25 indexed citations

18.

Pham, N. T. Hang, I. B. Cheglakov, Christine Koch, et al.. (2000). The guanine nucleotide exchange factor CNrasGEF activates Ras in response to cAMP and cGMP. Current Biology. 10(9). 555–558. 123 indexed citations

19.

Staub, Olivier & Daniela Rotin. (1996). WW domains. Structure. 4(5). 495–499. 76 indexed citations

20.

Spivak-Kroizman, Taly R., Daniela Rotin, Dalia Pinchasi, et al.. (1992). Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses.. Journal of Biological Chemistry. 267(12). 8056–8063. 95 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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