Christopher S. Hughes

4.8k total citations · 2 hit papers
26 papers, 2.5k citations indexed

About

Christopher S. Hughes is a scholar working on Molecular Biology, Spectroscopy and Cancer Research. According to data from OpenAlex, Christopher S. Hughes has authored 26 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 15 papers in Spectroscopy and 5 papers in Cancer Research. Recurrent topics in Christopher S. Hughes's work include Advanced Proteomics Techniques and Applications (14 papers), Mass Spectrometry Techniques and Applications (9 papers) and RNA Research and Splicing (5 papers). Christopher S. Hughes is often cited by papers focused on Advanced Proteomics Techniques and Applications (14 papers), Mass Spectrometry Techniques and Applications (9 papers) and RNA Research and Splicing (5 papers). Christopher S. Hughes collaborates with scholars based in Canada, Germany and United States. Christopher S. Hughes's co-authors include Jeroen Krijgsveld, Gregg B. Morin, Poul H. Sorensen, Torsten Müller, Lars M. Steinmetz, Eileen E. M. Furlong, David Garfield, Shane Colborne, Torsten O. Nielsen and Dawn R. Cochrane and has published in prestigious journals such as Nucleic Acids Research, Nature Communications and The Journal of Cell Biology.

In The Last Decade

Christopher S. Hughes

26 papers receiving 2.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

2018 977 citations Christopher S. Hughes, Torsten Müller et al. Nature Protocols profile →
Ultrasensitive proteome analysis using paramagnetic bead technology

2014 760 citations Christopher S. Hughes, David Garfield et al. Molecular Systems Biology profile →

Peers

Countries citing papers authored by Christopher S. Hughes

Since Specialization

Citations

This map shows the geographic impact of Christopher S. Hughes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher S. Hughes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher S. Hughes more than expected).

Fields of papers citing papers by Christopher S. Hughes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher S. Hughes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher S. Hughes. The network helps show where Christopher S. Hughes may publish in the future.

Co-authorship network of co-authors of Christopher S. Hughes

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher S. Hughes. A scholar is included among the top collaborators of Christopher S. Hughes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher S. Hughes. Christopher S. Hughes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pharmacologic Inhibition of EIF4A Blocks NRF2 Synthesis to Prevent Osteosarcoma Metastasis 2024 ·Clinical Cancer Research ·Michael M. Lizardo, Christopher S. Hughes, (unknown), (unknown), Alberto Delaidelli, Hai‐Feng Zhang, (unknown), (unknown), (unknown), Leanne C. Sayles, Alex G. Lee, E. Alejandro Sweet‐Cordero, Poul H. Sorensen	5
2	Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities 2024 ·Genome Medicine ·(unknown), Erin Pleasance, Alessia Gagliardi, Christopher S. Hughes, Veronika Csizmók, Kathleen Wee, Diane L. Trinh, Ryan D. Huff, Andrew J. Mungall, Richard A. Moore, Eric Chuah, Karen Mungall, (unknown), Jessica Nelson, Howard J. Lim, Daniel J. Renouf, Steven A. Jones, Janessa Laskin, Marco A. Marra	1
3	Tandem mass tag-based thermal proteome profiling for the discovery of drug-protein interactions in cancer cells 2023 ·STAR Protocols ·Fraser Johnson, Christopher S. Hughes, Alvin Liu, William W. Lockwood, Gregg B. Morin	3
4	Multi-Omic Analysis of CIC’s Functional Networks Reveals Novel Interaction Partners and a Potential Role in Mitotic Fidelity 2023 ·Cancers ·(unknown), Véronique Leblanc, (unknown), Susanna Chan, (unknown), Diane L. Trinh, Shiekh Tanveer Ahmad, (unknown), Richard Corbett, Alessia Gagliardi, Annie Moradian, J. Gregory Cairncross, Stephen Yip, Samuel Aparício, Jennifer A. Chan, Christopher S. Hughes, Gregg B. Morin, Sharon M. Gorski, Suganthi Chittaranjan, Marco A. Marra	3
5	Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes 2022 ·Nature Communications ·Karama Asleh, Gian Luca Negri, Sandra E. Spencer Miko, Shane Colborne, Christopher S. Hughes, Xiu Q. Wang, Dongxia Gao, C. Blake Gilks, Stephen Chia, Torsten O. Nielsen, Gregg B. Morin	82
6	HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner 2021 ·Oncogene ·(unknown), Fan Zhang, Amal M. El-Naggar, Gian Luca Negri, Melanie Kögler, Luigi Tortola, Fraser Johnson, Tony Ng, Amy Li, Donald T. Yapp, William W. Lockwood, Daniel Martínez, John M. Maris, Mads Daugaard, Josef Penninger, Christopher S. Hughes, Poul H. Sorensen	6
7	Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A 2021 ·Cell Reports ·George E. Allen, Olesya O. Panasenko, Zoltán Villányi, (unknown), Benjamin Weiss, (unknown), (unknown), Christine Polte, (unknown), Christopher S. Hughes, Vicent Pelechano, Zoya Ignatova, Martine A. Collart	24
8	A Standardized and Reproducible Proteomics Protocol for Bottom-Up Quantitative Analysis of Protein Samples Using SP3 and Mass Spectrometry 2019 ·Methods in molecular biology ·Christopher S. Hughes, Poul H. Sorensen, Gregg B. Morin	30
9	The FUS-DDIT3 Interactome in Myxoid Liposarcoma 2019 ·Neoplasia ·(unknown), Shane Colborne, Christopher S. Hughes, Gregg B. Morin, Torsten O. Nielsen	28
10	Extending the Compatibility of the SP3 Paramagnetic Bead Processing Approach for Proteomics 2018 ·Journal of Proteome Research ·(unknown), Poul H. Sorensen, Gregg B. Morin, Christopher S. Hughes	185
11	Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases 2018 ·Molecular Case Studies ·(unknown), Hui‐Li Wong, Melika Bonakdar, Martin Jones, Christopher S. Hughes, Gregg B. Morin, Steven J.M. Jones, Daniel J. Renouf, Howard J. Lim, Janessa Laskin, Marco A. Marra, Stephen Yip, David F. Schaeffer	13
12	Single-pot, solid-phase-enhanced sample preparation for proteomics experiments breakdown → 2018 ·Nature Protocols ·Christopher S. Hughes, (unknown), Torsten Müller, Poul H. Sorensen, Gregg B. Morin, Jeroen Krijgsveld	977
13	RawTools: Rapid and Dynamic Interrogation of Orbitrap Data Files for Mass Spectrometer System Management 2018 ·Journal of Proteome Research ·Kevin A. Kovalchik, Shane Colborne, Sandra E. Spencer Miko, Poul H. Sorensen, David D. Y. Chen, Gregg B. Morin, Christopher S. Hughes	17
14	Parsing and Quantification of Raw Orbitrap Mass Spectrometer Data Using RawQuant 2018 ·Journal of Proteome Research ·Kevin A. Kovalchik, (unknown), David D. Y. Chen, Gregg B. Morin, Christopher S. Hughes	7
15	CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion 2017 ·Nucleic Acids Research ·Jerry F. Tien, (unknown), Siwei Cheng, Christopher S. Hughes, Christalle C. T. Chow, (unknown), Arusha Oloumi, Genny Trigo‐Gonzalez, Ali Bashashati, James Xu, Vicky C. Chang, Sohrab P. Shah, Samuel Aparício, Gregg B. Morin	111
16	Translational Capacity of a Cell Is Determined during Transcription Elongation via the Ccr4-Not Complex 2016 ·Cell Reports ·Ishaan Gupta, Zoltán Villányi, (unknown), Christopher S. Hughes, Olesya O. Panasenko, Lars M. Steinmetz, Martine A. Collart	37
17	Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research 2016 ·Scientific Reports ·Christopher S. Hughes, Melissa K. McConechy, Dawn R. Cochrane, Tayyebeh M. Nazeran, Anthony N. Karnezis, David G. Huntsman, Gregg B. Morin	79
18	Ultrasensitive proteome analysis using paramagnetic bead technology breakdown → 2014 ·Molecular Systems Biology ·Christopher S. Hughes, (unknown), David Garfield, Eileen E. M. Furlong, Lars M. Steinmetz, Jeroen Krijgsveld	760
19	Human fibroblast matrices bio-assembled under macromolecular crowding support stable propagation of human embryonic stem cells 2012 ·Journal of Tissue Engineering and Regenerative Medicine ·(unknown), Michael Bocker, (unknown), Wei Seong Toh, Christopher S. Hughes, Fahad Kidwai, Gilles Lajoie, Tong Cao, Frank Lyko, Michael Raghunath	28
20	The Proteomic Analysis of Human FFPE Tissue by On-line 2D-LC-MS. 2010 ·Journal of Biomolecular Techniques JBT ·Christopher S. Hughes, J. Langridge, Niroshini Nirmalan, Rosamonde E. Banks, T. McKenna	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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