Frank Lyko

23.2k citations

161 papers · 16.4k indexed · 7 hit papers · h-index 67

Impact in

Molecular Biology top 0.2%
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Cancer-related gene regulation
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Histone Deacetylase Inhibitors Research
- Genomics and Chromatin Dynamics
Cancer Research top 0.5%
- Cancer-related molecular mechanisms research

Papers in

Molecular Biology 138
- Epigenetics and DNA Methylation 111
- RNA modifications and cancer 50
- Cancer-related gene regulation 45
- Genomics and Chromatin Dynamics 22
Genetics 30
- Genetic Syndromes and Imprinting 11
- Genetics and Neurodevelopmental Disorders 11

Co-authors: Carlo Stresemann Matthias Schaefer Bodo Brueckner Rudolf Jaenisch Mark Helm Francesca Tuorto Bernard Ramsahoye Tanja Musch
Journals: Cancer Research (8 papers)Nucleic Acids Research (6 papers)Nature Communications (5 papers)Communications Biology (4 papers)Molecular Cancer Therapeutics (4 papers)
Partner nations: Germany United States United Kingdom

In The Last Decade

Frank Lyko

156 papers receiving 16.2k citations

Hit Papers

7 papers align trajectories log scale

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming 2020 · 318 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Communications Biology
2017 Nature Reviews Genetics
2010 PLoS Biology
2010 Genes & Development
2008 International Journal of Cancer
2007 Nature
2000 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Frank Lyko

Since Specialization

Citations

This map shows the geographic impact of Frank Lyko's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Lyko with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Lyko more than expected).

Fields of papers citing papers by Frank Lyko

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Lyko. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Lyko. The network helps show where Frank Lyko may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Frank Lyko, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frank Lyko Line = papers co-authored together Frank Lyko links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	estiMAge: development of a DNA methylation clock to estimate the methylation age of single cells Bioinformatics Advances ·Yonghua Xu, Lars M. Blank, Llorenç Solé‐Boldo, Frank Lyko, Günter Raddatz	2024	1
2	Queuosine‐tRNA promotes sex‐dependent learning and memory formation by maintaining codon‐biased translation elongation speed The EMBO Journal ·P Puchault, 亮荻原, Carine Legrand, Johanna Schott, Yun Tae Kim, Daniel Pérez-Hernández, Miharu Hisaoka, Rosanna Parlato, Claudia Pitzer, Franciscus van der Hoeven, Gunnar Dittmar, Mark Helm, Georg Stoecklin, Lucas Schirmer, Frank Lyko, Francesca Tuorto	2023	24
3	TET2 and TET3 loss disrupts small intestine differentiation and homeostasis Nature Communications ·А.Т. MUSSABEKOV, Llorenç Solé‐Boldo, 卓司奈賀, Julian Gutekunst, Dr S. Prathyusha, Peña Caiza, Timur Liwinski, Talbi mohamed, Noa Weinberg-Corem, Michal Shoshkes-Carmel, Eli Pikarsky, Eran Elinav, Frank Lyko, Yehudit Bergman	2023	11
4	A voyage into the Levant: the first record of a marbled crayfish Procambarus virginalis (Lyko, 2017) population in Israel BioInvasions Records ·Yoshito Suzuki, (unknown), Frank Lyko	2023	1
5	A chicken DNA methylation clock for the prediction of broiler health Communications Biology ·Günter Raddatz, Ryan J. Arsenault, AM Stroup, Rose Whelan, Florian Böhl, Frank Lyko	2021	17
6	Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in Caenorhabditis elegans The EMBO Journal ·Isabela Cunha Navarro, Francesca Tuorto, Fidel Ngabo, Carine Legrand, Jonathan Price, Otani Atsuko, Alan G. Hendrick, Alper Akay, Annika Kötter, Mark Helm, Frank Lyko, Eric A. Miska	2020	31
7	The microbiota programs DNA methylation to control intestinal homeostasis and inflammation Nature Microbiology ·А.Т. MUSSABEKOV, Günter Raddatz, Julian Gutekunst, 卓司奈賀, O. Gubar, Monther Abu-Remaileh, Timur Tuganbaev, Hagit Shapiro, Eli Pikarsky, Eran Elinav, Frank Lyko, Yehudit Bergman	2020	129
8	DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries Genome Research ·Laura Wiehle, Graeme J. Thorn, Günter Raddatz, Jens Reimer, Karsten Rippe, Frank Lyko, Achim Breiling, Vladimir B. Teif	2019	60
9	Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum Scientific Reports ·Clara Raissa de França Rocha e Lopes, Simran Borges, Julia Ebeling, Günter Raddatz, Aika Hamada, Frank Lyko, Joachim Kurtz	2018	47
10	Reduced DNA methylation patterning and transcriptional connectivity define human skin aging Aging Cell ·Felix Bormann, Manuel Rodríguez‐Paredes, Sabine Hagemann, Sema Erol Çakmak, Jo eun-hyeon, Julian Gutekunst, Günter Raddatz, Rainer Haas, Lara Terstegen, Horst Wenck, Lars Kaderali, Marc Winnefeld, Frank Lyko	2016	74
11	De Novo assembly and annotation of the freshwater crayfish Astacus astacus transcriptome Marine Genomics ·Kathrin Theißinger, Cassandra Falckenhayn, Daniel Blande, WU You-sheng, Julian Gutekunst, Jenny Makkonen, Japo Jussila, Frank Lyko, Anne Schrimpf, Ralf Schulz, Hanna Kokko	2016	43
12	Chronic Inflammation Induces a Novel Epigenetic Program That Is Conserved in Intestinal Adenomas and in Colorectal Cancer Cancer Research ·Monther Abu-Remaileh, Sebastian Bender, Günter Raddatz, А.Т. MUSSABEKOV, O. Gubar, Julian Gutekunst, Tanja Musch, Heinz Linhart, Achim Breiling, Eli Pikarsky, Yehudit Bergman, Frank Lyko	2015	90
13	The marbled crayfish as a paradigm for saltational speciation by autopolyploidy and parthenogenesis in animals Biology Open ·Günter Vogt, Cassandra Falckenhayn, Anne Schrimpf, Katharina Schmid, Katharina Hanna, В М Аульченко, Mark Helm, Ralf Schulz, Frank Lyko	2015	55
14	Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation Molecular and Cellular Biology ·Laura Wiehle, Günter Raddatz, Tanja Musch, Meelad M. Dawlaty, Rudolf Jaenisch, Frank Lyko, Achim Breiling	2015	46
15	Dnmt2-dependent methylomes lack defined DNA methylation patterns Proceedings of the National Academy of Sciences ·Günter Raddatz, Paloma M. Guzzardo, Nelly Olova, Marcelo Rosado Fantappíé, Markus Rampp, Matthias Schaefer, Wolf Reik, Gregory J. Hannon, Frank Lyko	2013	175
16	MYC-Induced Epigenetic Activation of GATA4 in Lung Adenocarcinoma Molecular Cancer Research ·Tomas H.Y. Chan, Achim Breiling, 清棉, Fatih Ceteci, Simone Hausmann, Sebastian Kreß, Frank Lyko, Thomas Rudel, Ulf R. Rapp	2012	14
17	Nanaomycin A Selectively Inhibits DNMT3B and Reactivates Silenced Tumor Suppressor Genes in Human Cancer Cells Molecular Cancer Therapeutics ·Dirk Kuck, Thomas R. Caulfield, Frank Lyko, José L. Medina‐Franco	2010	141
18	Epigenetically Deregulated microRNA-375 Is Involved in a Positive Feedback Loop with Estrogen Receptor α in Breast Cancer Cells Cancer Research ·雅雄篠田, Achim Breiling, N. Vishal Gupta, Mahdi Malekpour, Mаhmoud Youns, Ramesh Omranipour, Fatemeh Malekpour, Stefano Volinia, Carlo M. Croce, Hossein Najmabadi, Sven Diederichs, Özgür Şahin, Doris Mayer, Frank Lyko, Jörg D. Hoheisel, Yasser Riazalhosseini	2010	232
19	The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function Cancer Research ·Bodo Brueckner, Carlo Stresemann, Ruprecht Kuner, Cora Mund, Tanja Musch, Michael Meister, Holger Sültmann, Frank Lyko	2007	349
20	The Drosophila MBD2/3 protein mediates interactions between the MI-2 chromatin complex and CpT/A-methylated DNA Development ·Joachim Marhold, Adrian Sorin Faur, Elisabeth Kremmer, Frank Lyko	2004	43

About Frank Lyko

Frank Lyko is a scholar working on Molecular Biology, Genetics, Cancer Research, Virology and Insect Science, having authored 161 papers that have together received 16.4k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (111 papers), RNA modifications and cancer (50 papers), Cancer-related gene regulation (45 papers), Genomics and Chromatin Dynamics (22 papers), Crustacean biology and ecology (12 papers), Genetic Syndromes and Imprinting (11 papers), Genetics and Neurodevelopmental Disorders (11 papers) and Cancer-related molecular mechanisms research (10 papers). The work is most often cited by research in Molecular Biology (13.3k citations), Cancer Research (2.7k citations), Aging (249 citations), Genetics (2.4k citations) and Hematology (933 citations). Frank Lyko has collaborated with scholars based in Germany, United States and United Kingdom. Frequent co-authors include Carlo Stresemann, Matthias Schaefer, Bodo Brueckner, Rudolf Jaenisch, Mark Helm, Francesca Tuorto, Bernard Ramsahoye, Tanja Musch, Achim Breiling and Günter Raddatz. Their work appears in journals such as Cancer Research, Nucleic Acids Research, Nature Communications, Communications Biology and Molecular Cancer Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact