Alan B. Sachs

12.0k citations

62 papers · 8.9k indexed · 6 hit papers · h-index 41

Impact in

Molecular Biology top 0.5%
- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Fungal and yeast genetics research
- RNA Interference and Gene Delivery
- RNA regulation and disease
- Advanced biosensing and bioanalysis techniques
Cardiology and Cardiovascular Medicine top 2%
- Viral Infections and Immunology Research

Papers in

Molecular Biology 58
- RNA Research and Splicing 34
- RNA and protein synthesis mechanisms 31
- Fungal and yeast genetics research 16
- RNA Interference and Gene Delivery 9
- Advanced biosensing and bioanalysis techniques 8
- RNA modifications and cancer 4
- Ion channel regulation and function 4
Cancer Research 9
- MicroRNA in disease regulation 7

Co-authors: Salvador Z. Tarun Ronald W. Davis Roger D. Kornberg Matthias W. Hentze Peter Sarnow Ronald D. Vale P. E. Hillner Christine E. Brown
Journals: Molecular and Cellular Biology (10 papers)Cell (7 papers)RNA (5 papers)Analytical Biochemistry (3 papers)Journal of Biological Chemistry (3 papers)
Partner nations: United States United Kingdom Germany

In The Last Decade

Alan B. Sachs

61 papers receiving 8.7k citations

Hit Papers

6 papers align trajectories log scale

Circularization of mRNA by Eukaryotic Translation Initiation Factors 1998 · 743 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1998 Molecular Cell
1997 Cell
1996 The EMBO Journal
1993 Cell
1987 Molecular and Cellular Biology
1986 Cell

Peers

Countries citing papers authored by Alan B. Sachs

Since Specialization

Citations

This map shows the geographic impact of Alan B. Sachs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan B. Sachs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan B. Sachs more than expected).

Fields of papers citing papers by Alan B. Sachs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan B. Sachs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan B. Sachs. The network helps show where Alan B. Sachs may publish in the future.

Co-authors

The 25 scholars most cited alongside Alan B. Sachs, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alan B. Sachs Line = papers co-authored together Alan B. Sachs links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	RNA-Induced Silencing Complex-Bound Small Interfering RNA Is a Determinant of RNA Interference-Mediated Gene Silencing in Mice Molecular Pharmacology ·Jie Wei, Jeffrey J. Jones, Jing Kang, Ananda Card, Michael Krimm, Paula J. Hancock, Yi Pei, Brandon Ason, Elmer Payson, Natalya Dubinina, Mark T. Cancilla, Mark Stroh, Julja Burchard, Alan B. Sachs, Jerome Hochman, W. Michael Flanagan, Nelly A. Kuklin	2011	40
2	Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9 Journal of Lipid Research ·Brandon Ason, Samnang Tep, Jr. Harry R. Davis, Yiming Xu, Glen Tetzloff, Beverly Galinski, Ferdie Soriano, Natalya Dubinina, Lei Zhu, Alice Stefanni, Kenny K. Wong, Marija Tadin‐Strapps, Steven R. Bartz, Brian K. Hubbard, Mollie Ranalletta, Alan B. Sachs, W. Michael Flanagan, Alison M. Strack, Nelly A. Kuklin	2011	36
3	Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses Molecular Therapy ·Weikang Tao, Xianzhi Mao, Joseph P. Davide, Bruce Ng, Mingmei Cai, Paul A. Burke, Alan B. Sachs, Laura Sepp‐Lorenzino	2010	57
4	Persistence of seed-based activity following segmentation of a microRNA guide strand RNA ·Guillaume Chorn, Lihong Zhao, Alan B. Sachs, W. Michael Flanagan, Lee P. Lim	2010	7
5	The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing Nucleic Acids Research ·Walter Strapps, Victoria Pickering, Gladys T. Muiru, Julie Rice, Stacey Orsborn, Barry Polisky, Alan B. Sachs, Steven R. Bartz	2010	46
6	Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment Molecular Therapy ·Marc Abrams, Martin L. Koser, Jessica Seitzer, Stephanie Williams, Martha A. DiPietro, Weimin Wang, Andrew W. Shaw, Xianzhi Mao, Vasant Jadhav, Joseph P. Davide, Paul A. Burke, Alan B. Sachs, Steven M. Stirdivant, Laura Sepp‐Lorenzino	2009	165
7	A Cell Proliferation Signature Is a Marker of Extremely Poor Outcome in a Subpopulation of Breast Cancer Patients Cancer Research ·Hongyue Dai, Laura van’t Veer, John R. Lamb, Yudong D. He, Mao Mao, Bernard M. Fine, René Bernards, Marc J. van de Vijver, Paul Deutsch, Alan B. Sachs, Roland Stoughton, Stephen Friend	2005	207
8	Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels Genomics ·Alessandra Cervino, Guoya Li, Stephen W. Edwards, Jun Zhu, Cathy C. Laurie, George Tokiwa, Pek Yee Lum, Susanna Wang, Lawrence W. Castellini, Aldons J. Lusis, Sonia Carlson, Alan B. Sachs, Eric E. Schadt	2005	114
9	One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs RNA ·Toshifumi Inada, Éric Winstall, Salvador Z. Tarun, John R. Yates, DAVE SCHIELTZ, Alan B. Sachs	2002	106
10	10 Physical and Functional Interactions between the mRNA Cap Structure and the Poly(A) Tail Cold Spring Harbor Monograph Archive ·Alan B. Sachs	2000	20
11	The Saccharomyces cerevisiae RNA-binding Protein Rbp29 Functions in Cytoplasmic mRNA Metabolism Journal of Biological Chemistry ·Éric Winstall, Martin C. Sadowski, Uwe Kühn, Elmar Wahle, Alan B. Sachs	2000	30
12	Cell Cycle–Dependent Translation Initiation Cell ·Alan B. Sachs	2000	91
13	Eukaryotic translation initiation: there are (at least) two sides to every story. Nature Structural Biology ·Alan B. Sachs, Gabriele Varani	2000	113
14	RNA Recognition Motif 2 of Yeast Pab1p Is Required for Its Functional Interaction with Eukaryotic Translation Initiation Factor 4G Molecular and Cellular Biology ·Steven H. Kessler, Alan B. Sachs	1998	132
15	Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation Molecular and Cellular Biology ·Christine E. Brown, Alan B. Sachs	1998	188
16	Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast Poly(A)-binding protein Journal of Molecular Biology ·Julie A. Deardorff, Alan B. Sachs	1997	88
17	Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes Cell ·Alan B. Sachs, Peter Sarnow, Matthias W. Hentze Hit paper breakdown →	1997	571
18	PAN3 Encodes a Subunit of the Pab1p-Dependent Poly(A) Nuclease in Saccharomyces cerevisiae Molecular and Cellular Biology ·Christine E. Brown, Salvador Z. Tarun, Ronald Boeck, Alan B. Sachs	1996	132
19	The Yeast Pan2 Protein Is Required for Poly(A)-binding Protein-stimulated Poly(A)-nuclease Activity Journal of Biological Chemistry ·Ronald Boeck, Salvador Z. Tarun, Michael A. Rieger, Julie A. Deardorff, S. Müller-Auer, Alan B. Sachs	1996	152
20	Nuclear Polyadenylate-Binding Protein Molecular and Cellular Biology ·Alan B. Sachs, Roger D. Kornberg	1985	31

About Alan B. Sachs

Alan B. Sachs is a scholar working on Molecular Biology, Cancer Research, Bioengineering, Endocrinology and Cardiology and Cardiovascular Medicine, having authored 62 papers that have together received 8.9k indexed citations. Recurring topics across this work include RNA Research and Splicing (34 papers), RNA and protein synthesis mechanisms (31 papers), Fungal and yeast genetics research (16 papers), RNA Interference and Gene Delivery (9 papers), Advanced biosensing and bioanalysis techniques (8 papers), MicroRNA in disease regulation (7 papers), RNA modifications and cancer (4 papers) and Ion channel regulation and function (4 papers). The work is most often cited by research in Molecular Biology (7.8k citations), Cardiology and Cardiovascular Medicine (929 citations), Cancer Research (502 citations), Genetics (921 citations) and Aging (53 citations). Alan B. Sachs has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Salvador Z. Tarun, Ronald W. Davis, Roger D. Kornberg, Matthias W. Hentze, Peter Sarnow, Ronald D. Vale, P. E. Hillner, Christine E. Brown, M W Bond and Susan K. De Long. Their work appears in journals such as Molecular and Cellular Biology, Cell, RNA, Analytical Biochemistry and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact