Christian Oefner

7.4k total citations · 1 hit paper
39 papers, 6.0k citations indexed

About

Christian Oefner is a scholar working on Molecular Biology, Oncology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Christian Oefner has authored 39 papers receiving a total of 6.0k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 10 papers in Oncology and 7 papers in Cellular and Molecular Neuroscience. Recurrent topics in Christian Oefner's work include Peptidase Inhibition and Analysis (10 papers), Neuropeptides and Animal Physiology (7 papers) and Enzyme Structure and Function (7 papers). Christian Oefner is often cited by papers focused on Peptidase Inhibition and Analysis (10 papers), Neuropeptides and Animal Physiology (7 papers) and Enzyme Structure and Function (7 papers). Christian Oefner collaborates with scholars based in Switzerland, United States and United Kingdom. Christian Oefner's co-authors include Dietrich Suck, Felix Frolow, Joel L. Sussman, Michal Harel, Lilly Toker, Adrian Goldman, Israel Silman, A. D’Arcy, Glenn E. Dale and Fritz K. Winkler and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Christian Oefner

39 papers receiving 5.8k citations

Hit Papers

Atomic Structure of Acetylcholinesterase from Torpedo cal... 1991 2026 2002 2014 1991 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein
    1991 2.2k citations Christian Oefner et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christian Oefner Switzerland 31 3.5k 1.9k 1.2k 1.1k 595 39 6.0k
Stanislav Gobec Slovenia 46 3.6k 1.0× 1.7k 0.9× 1.5k 1.3× 2.7k 2.5× 646 1.1× 298 7.6k
Alexander W. Schüttelkopf United Kingdom 25 4.1k 1.2× 438 0.2× 787 0.7× 1.3k 1.2× 570 1.0× 32 6.3k
Andrew C. Wallace United States 11 5.0k 1.4× 404 0.2× 909 0.8× 887 0.8× 579 1.0× 12 7.0k
Milton T. Stubbs Germany 41 3.4k 1.0× 633 0.3× 424 0.4× 598 0.5× 607 1.0× 117 5.6k
Maurizio Botta Italy 54 5.5k 1.6× 971 0.5× 659 0.6× 5.7k 5.2× 1.1k 1.8× 436 11.9k
Jordan Tang United States 53 4.8k 1.4× 1.7k 0.9× 1.8k 1.6× 757 0.7× 996 1.7× 173 9.1k
Brian S. J. Blagg United States 53 6.4k 1.8× 627 0.3× 1.6k 1.4× 1.2k 1.1× 448 0.8× 227 8.3k
Wolfgang Sippl Germany 57 6.4k 1.8× 830 0.4× 1.3k 1.1× 1.6k 1.5× 1.7k 2.9× 303 10.3k
Walter Filgueira de Azevedo Brazil 44 4.5k 1.3× 506 0.3× 2.0k 1.7× 1.3k 1.2× 1.1k 1.9× 199 7.1k
Michael A. Walters United States 29 2.2k 0.6× 564 0.3× 633 0.5× 1.1k 1.0× 484 0.8× 98 5.0k

Countries citing papers authored by Christian Oefner

Since Specialization
Citations

This map shows the geographic impact of Christian Oefner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christian Oefner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christian Oefner more than expected).

Fields of papers citing papers by Christian Oefner

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christian Oefner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christian Oefner. The network helps show where Christian Oefner may publish in the future.

Co-authorship network of co-authors of Christian Oefner

This figure shows the co-authorship network connecting the top 25 collaborators of Christian Oefner. A scholar is included among the top collaborators of Christian Oefner based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christian Oefner. Christian Oefner is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Oefner, Christian, M. Bandera, Andreas Haldimann, et al.. (2009). Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. Journal of Antimicrobial Chemotherapy. 63(4). 687–698. 83 indexed citations
2.
Oefner, Christian, Sandro Parisi, Henk Schulz, Sergio Lociuro, & Glenn E. Dale. (2009). Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase fromStaphylococcus aureus. Acta Crystallographica Section D Biological Crystallography. 65(8). 751–757. 34 indexed citations
3.
Oefner, Christian, et al.. (2007). Structural studies of a bifunctional inhibitor of neprilysin and DPP-IV. Acta Crystallographica Section D Biological Crystallography. 63(9). 975–981. 36 indexed citations
4.
Oefner, Christian, Henk Schulz, A. D’Arcy, & Glenn E. Dale. (2006). Mapping the active site ofEscherichia colimalonyl-CoA–acyl carrier protein transacylase (FabD) by protein crystallography. Acta Crystallographica Section D Biological Crystallography. 62(6). 613–618. 81 indexed citations
5.
Oefner, Christian, et al.. (2003). High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[({2-[(5-iodopyridin-2-yl)amino]-ethyl}amino)-acetyl]-2-cyano-(S)-pyrrolidine. Acta Crystallographica Section D Biological Crystallography. 59(7). 1206–1212. 69 indexed citations
6.
Dale, Glenn E., Christian Oefner, & A. D’Arcy. (2003). The protein as a variable in protein crystallization. Journal of Structural Biology. 142(1). 88–97. 137 indexed citations
7.
Bur, Daniel, Glenn E. Dale, & Christian Oefner. (2001). A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP). Protein Engineering Design and Selection. 14(5). 337–341. 25 indexed citations
8.
Oefner, Christian, A. D’Arcy, Michael Hennig, Fritz K. Winkler, & Glenn E. Dale. (2000). Structure of human neutral endopeptidase (neprilysin) complexed with phosphoramidon 1 1Edited by R. Huber. Journal of Molecular Biology. 296(2). 341–349. 221 indexed citations
9.
Dale, Glenn E., et al.. (2000). Purification and crystallization of the extracellular domain of human neutral endopeptidase (neprilysin) expressed inPichia pastoris. Acta Crystallographica Section D Biological Crystallography. 56(7). 894–897. 8 indexed citations
10.
Vieira, Eric, Alfred Binggeli, Volker Breu, et al.. (1999). Substituted piperidines - highly potent renin inhibitors due to induced fit adaptation of the active site. Bioorganic & Medicinal Chemistry Letters. 9(10). 1397–1402. 79 indexed citations
11.
Hennig, Michael, Glenn E. Dale, A. D’Arcy, et al.. (1999). The structure and function of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Haemophilus influenzae 1 1Edited by R. Huber. Journal of Molecular Biology. 287(2). 211–219. 51 indexed citations
12.
Güller, Rolf, Alfred Binggeli, Volker Breu, et al.. (1999). Piperidine-renin inhibitors compounds with improved physicochemical properties. Bioorganic & Medicinal Chemistry Letters. 9(10). 1403–1408. 52 indexed citations
13.
Ampè, Christophe, et al.. (1998). Analysis of three human interleukin 5 structures suggests a possible receptor binding mechanism. FEBS Letters. 424(3). 121–126. 6 indexed citations
14.
Moon, Richard P., Daniel Bur, Hansruedi Loetscher, et al.. (1998). Studies on Plasmepsins I and II from the Malarial Parasite Plasmodium falciparum and their Exploitation as Drug Targets. Advances in experimental medicine and biology. 436. 397–406. 15 indexed citations
15.
D’Arcy, A., Glenn E. Dale, Dirk Kostrewa, et al.. (1997). Structure and function of the dihydropteroate synthase from staphylococcus aureus. Journal of Molecular Biology. 268(1). 21–30. 152 indexed citations
16.
Dale, Glenn E., Clemens Broger, Peter Hartman, et al.. (1997). A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance 1 1 Edited by T.Richmond. Journal of Molecular Biology. 266(1). 23–30. 130 indexed citations
17.
Oefner, Christian, Ernst‐Jürgen Schlaeger, M. Zulauf, et al.. (1993). Expression, purification and crystallization of fully active, glycosylated human interleukin‐5. FEBS Letters. 331(1-2). 49–52. 8 indexed citations
18.
Murray‐Rust, Judith, Tom L. Blundell, Markus Hosang, et al.. (1993). Topological similarities in TGF-β2, PDGF-BB and NGF define a superfamily of polypeptide growth factors. Structure. 1(2). 153–159. 114 indexed citations
19.
Oefner, Christian, A. D’Arcy, J. J. Daly, et al.. (1990). Refined crystal structure of β-lactamase from Citrobacter freundiiindicates a mechanism for β-lactam hydrolysis. Nature. 343(6255). 284–288. 260 indexed citations
20.
Suck, Dietrich, Armin Lahm, & Christian Oefner. (1988). Structure refined to 2Å of a nicked DNA octanucleotide complex with DNase I. Nature. 332(6163). 464–468. 270 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Stanislav Gobec Breakdown of academic impact, for papers by Alexander W. Schüttelkopf Breakdown of academic impact, for papers by Andrew C. Wallace Breakdown of academic impact, for papers by Milton T. Stubbs Breakdown of academic impact, for papers by Maurizio Botta Breakdown of academic impact, for papers by Jordan Tang Breakdown of academic impact, for papers by Brian S. J. Blagg Breakdown of academic impact, for papers by Wolfgang Sippl Breakdown of academic impact, for papers by Walter Filgueira de Azevedo Breakdown of academic impact, for papers by Michael A. Walters
Rankless by CCL
2026