Chih Min Kam

1.2k citations

20 papers · 1.1k indexed · h-index 15

Immunology top 10%
Hematology top 10%
- Blood Coagulation and Thrombosis Mechanisms 3
Cancer Research
- Synthesis and Biological Activity 7
- Protease and Inhibitor Mechanisms 4
Molecular Biology
- Chemical Synthesis and Analysis 4
- PI3K/AKT/mTOR signaling in cancer 2
Oncology
- Peptidase Inhibition and Analysis 6
Organic Chemistry
- Synthesis and biological activity 2
Pharmacology
- Biological Stains and Phytochemicals 2

Co-authors: James C. Powers Harry B. Greenberg Ruedi Aebersold L Shi Shinjiro Odake Martin Poe Lakshmi Narasimhan Olivier Krähenbühl
Cited by: Immunology Hematology Cancer Research
Journals: Journal of the American Chemical Society (2 papers)Journal of Biological Chemistry (2 papers)The Journal of Experimental Medicine (1 paper)
Partner nations: United States Australia Canada

In The Last Decade

Chih Min Kam

20 papers receiving 1.0k citations

Peers

Countries citing papers authored by Chih Min Kam

Since Specialization

Citations

This map shows the geographic impact of Chih Min Kam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chih Min Kam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chih Min Kam more than expected).

Fields of papers citing papers by Chih Min Kam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chih Min Kam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chih Min Kam. The network helps show where Chih Min Kam may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Chih Min Kam, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Chih Min Kam Line = papers co-authored together Chih Min Kam links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A Serine Proteinase Inactivator Inhibits Chondrocyte-Mediated Cartilage Proteoglycan Breakdown Occurring in Response to Proinflammatory Cytokines Archives of Biochemistry and Biophysics ·Heather BRYSON,R.A.D. Bunning,Ruth E. Feltell,Chih Min Kam,John E. Kerrigan,James C. Powers,David J. Buttle	1998	14
2	Determination of Activable Proacrosin/Acrosin in Bovine Sperm Using an Irreversible Isocoumarin Serine Protease Inhibitor1 Biology of Reproduction ·Diego da Silva Palência,Duane L. Garner,Dorothy Hudig,D. W. Holcombe,C. A. Burner,Doug Redelman,George C.J. Fernandez,Ahmed S. Abuelyaman,Chih Min Kam,James C. Powers	1996	8
3	Mammalian Tissue Trypsin-like Enzymes: Substrate Specificity and Inhibitory Potency of Substituted Isocoumarin Mechanism-Based Inhibitors, Benzamidine Derivatives, and Arginine Fluoroalkyl Ketone Transition-State Inhibitors Archives of Biochemistry and Biophysics ·Chih Min Kam,María Hernández,Gautam Patil,Teruo Ueda,W.H. Simmons,Vincent Braganza,James C. Powers	1995	9
4	Inhibition of Porcine Pancreatic Elastase by 7-Substituted 4-Chloro-3-Ethoxyisocoumarins: Structural Characteristics of Modeled Noncovalent Complexes Relate to the Measured Inhibition Kinetics Archives of Biochemistry and Biophysics ·R. Richard Plaskon,Chih Min Kam,John E. Kerrigan,Edward M. Burgess,James C. Powers,F. L. Suddath	1993	3
5	Proteases—Structures, Mechanism and Inhibitors Birkhäuser Basel eBooks ·James C. Powers,Shinjiro Odake,Józef Oleksyszyn,Hitoshi Hori,Takuya Ueda,Bogdan Boduszek,Chih Min Kam	1993	20
6	Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases Bioconjugate Chemistry ·Chih Min Kam,Ahmed S. Abuelyaman,Zhaozhao Li,Dorothy Hudig,James C. Powers	1993	58
7	Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. The Journal of Experimental Medicine ·L Shi,Chih Min Kam,James C. Powers,Ruedi Aebersold,Harry B. Greenberg	1992	392
8	Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G Journal of Medicinal Chemistry ·David E. Zembower,Chih Min Kam,James C. Powers,Leon H. Zalkow	1992	32
9	Substituted isocoumarins as inhibitors of complement serine proteases The Journal of Immunology ·Chih Min Kam,T J Oglesby,Michael K. Pangburn,John E. Volanakis,James C. Powers	1992	28
10	Purification and cloning of a novel serine protease, RNK-Met-1, from the granules of a rat natural killer cell leukemia. Journal of Biological Chemistry ·Mark J. Smyth,T A Wiltrout,Joseph A. Trapani,K.S. Ottaway,R Sowder,L E Henderson,Chih Min Kam,James C. Powers,Howard A. Young,Thomas J. Sayers	1992	52
11	Synthetic substrates and inhibitors for serine proteases from lymphocytes, mast cells, semen, and blood. PubMed ·James C. Powers,Shinjiro Odake,Takuya Ueda,Dorothy Hudig,Howard C.B. Graves,Mehraneh Mohammadabadi Kamarei,Chih Min Kam	1992	1
12	Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex Biochemistry ·J. Vijayalakshmi,Edgar F. Meyer,Chih Min Kam,James C. Powers	1991	24
13	Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins Biochemistry ·Shinjiro Odake,Chih Min Kam,Lakshmi Narasimhan,Martin Poe,Joseph T. Blake,Olivier Krähenbühl,J Tschopp,James C. Powers	1991	217
14	Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin Biochemistry ·James C. Powers,Józef Oleksyszyn,S. Narasimhan,Chih Min Kam,R. Radhakrishnan,E. F. Meyer	1990	30
15	In vivo determination of the anticoagulant effect of a substituted isocoumarin (acitic) Thrombosis Research ·Steven W. Oweida,David N. Ku,Alan B. Lumsden,Chih Min Kam,James C. Powers	1990	6
16	The 2.2 .ANG. resolution x-ray crystal structure of the complex of trypsin inhibited by 4-chloro-3-ethoxy-7-guanidinoisocoumarin: a proposed model of the thrombin-inhibitor complex Journal of the American Chemical Society ·Margaret M. Chow,Edgar F. Meyer,Wolfram Bode,Chih Min Kam,R. Radhakrishnan,J. Vijayalakshmi,James C. Powers	1990	18
17	The synthesis of arginylfluoroalkanes, their inhibition of trypsin and blood-coagulation serine proteinases and their anticoagulant activity Biochemical Journal ·Takuya Ueda,Chih Min Kam,James C. Powers	1990	19
18	Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants Biochemistry ·Chih Min Kam,Kazuo Fujikawa,James C. Powers	1988	64
19	Human complement proteins D, C2, and B. Active site mapping with peptide thioester substrates. Journal of Biological Chemistry ·Chih Min Kam,Brian J. McRae,J. Wade Harper,Marilyn A. Niemann,John E. Volanakis,James C. Powers	1987	50
20	Mechanism-based isocoumarin inhibitors for trypsin-like serine proteases involved in blood coagulation Journal of the American Chemical Society ·Chih Min Kam,J. Clay Copher,James C. Powers	1987	16

About Chih Min Kam

Chih Min Kam is a scholar working on Cancer Research, Hematology and Oncology, having authored 20 papers that have together received 1.1k indexed citations. Recurring topics across this work include Synthesis and Biological Activity (7 papers), Peptidase Inhibition and Analysis (6 papers), Chemical Synthesis and Analysis (4 papers), Protease and Inhibitor Mechanisms (4 papers), Blood Coagulation and Thrombosis Mechanisms (3 papers), Synthesis and biological activity (2 papers), Biological Stains and Phytochemicals (2 papers) and PI3K/AKT/mTOR signaling in cancer (2 papers). The work is most often cited by research in Immunology (364 citations), Hematology (145 citations) and Cancer Research (151 citations). Chih Min Kam has collaborated with scholars based in United States, Australia and Canada. Frequent co-authors include James C. Powers, Harry B. Greenberg, Ruedi Aebersold, L Shi, Shinjiro Odake, Martin Poe, Lakshmi Narasimhan, Olivier Krähenbühl, J Tschopp and James C. Powers. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and The Journal of Experimental Medicine.

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