John E. Volanakis

11.3k citations

155 papers · 9.1k indexed · 4 hit papers · h-index 51

Impact in

Immunology top 0.2%
- Complement system in diseases
- Immunodeficiency and Autoimmune Disorders
Hematology top 0.5%
- Blood Coagulation and Thrombosis Mechanisms

Papers in

Hematology 59
- Blood groups and transfusion 30
- Blood Coagulation and Thrombosis Mechanisms 16
- Iron Metabolism and Disorders 11
Immunology 88
- Complement system in diseases 66

Co-authors: Melvin H. Kaplan Alexander J. Szalai M. H. Kaplan Sthanam V.L. Narayana David E. Briles Robert M. Stroud Kevin Macon Trevor J. Greenhough
Journals: The Journal of Immunology (37 papers)Molecular Immunology (8 papers)Journal of Molecular Biology (7 papers)Journal of Biological Chemistry (5 papers)Journal of Immunological Methods (5 papers)
Partner nations: United States Greece United Kingdom

In The Last Decade

John E. Volanakis

155 papers receiving 8.6k citations

Hit Papers

align trajectories log scale

Human C-reactive protein: expression, structure, and function 2001 · 707 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2001 Molecular Immunology
1974 The Journal of Immunology
1974 PubMed
1971 Experimental Biology and Medicine

Peers

Countries citing papers authored by John E. Volanakis

Since Specialization

Citations

This map shows the geographic impact of John E. Volanakis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Volanakis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Volanakis more than expected).

Fields of papers citing papers by John E. Volanakis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Volanakis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Volanakis. The network helps show where John E. Volanakis may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John E. Volanakis, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John E. Volanakis Line = papers co-authored together John E. Volanakis links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation Acta Crystallographica Section D Biological Crystallography ·Vengadesan Krishnan, Yuanyuan Xu, Kevin Macon, John E. Volanakis, Sthanam V.L. Narayana	2009	26
2	Structural Analysis of Engineered Bb Fragment of Complement Factor B Molecular Cell ·Karthe Ponnuraj, Yuanyuan Xu, Kevin Macon, Dwight Moore, John E. Volanakis, Sthanam V.L. Narayana	2004	64
3	A novel murine complement-related gene encoding a C1r-like serum protein Molecular Immunology ·Antonella Circolo, Gérard Garnier, John E. Volanakis	2003	9
4	Calnexin is associated with and induced by overexpressed human complement protein C2 The Anatomical Record ·Hiroshi Tsukamoto, Albert Tousson, Antonella Circolo, Richard B. Marchase, John E. Volanakis	2002	6
5	The three-dimensional structure of calcium-depleted human C-reactive protein from perfectly twinned crystals Acta Crystallographica Section D Biological Crystallography ·Mohamed Ramadan, A.K. Shrive, David W. Holden, Dean A. A. Myles, John E. Volanakis, L.J. DeLucas, Trevor J. Greenhough	2002	27
6	Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D The EMBO Journal ·Jing Hua, Kevin Macon, Dwight Moore, Lawrence J. DeLucas, John E. Volanakis, Sthanam V.L. Narayana	1999	51
7	The evolution, structure, biology and pathophysiology of complement Immunology Today ·John D. Lambris, Kenneth B. M. Reid, John E. Volanakis	1999	39
8	Complement factor D, a novel serine protease Protein Science ·John E. Volanakis, Sthanam V.L. Narayana	1996	118
9	Catalytic role of a surface loop of the complement serine protease factor D. The Journal of Immunology ·邹帆, Sthanam V.L. Narayana, John E. Volanakis	1995	13
10	Structure of Human Factor D Journal of Molecular Biology ·Sthanam V.L. Narayana, Mike Carson, Ossama El‐Kabbani, J. Michael Kilpatrick, Dwight Moore, Xi Chen, Charles E. Bugg, John E. Volanakis, Lawrence J. DeLucas	1994	68
11	Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency. Journal of Clinical Investigation ·John E. Volanakis, S. Thirupathirajan, Frederick M. Schaffer, Kevin Macon, Oleksii Kuznetsov, Bruce O. Barger, Rodney C.P. Go, R. Duncan Campbell, Harry W. Schroeder, Max D. Cooper	1992	101
12	Genetic and immunologic analysis of a family containing five patients with common-variable immune deficiency or selective IgA deficiency Journal of Clinical Immunology ·Robert F. Ashman, ITALO DE VATTIMO, John D. Kemp, Wayne M. Yokoyama, Zeng B. Zhu, Max D. Cooper, John E. Volanakis	1992	37
13	A variable number of tandem repeats locus within the human complement C2 gene is associated with a retroposon derived from a human endogenous retrovirus. The Journal of Experimental Medicine ·Zeng B. Zhu, Shu‐Ling Hsieh, D. R. Bentley, R. Duncan Campbell, John E. Volanakis	1992	40
14	Crystallization and preliminary X-ray investigation of factor D of human complement Journal of Molecular Biology ·Sthanam V.L. Narayana, J. Michael Kilpatrick, Ossama El‐Kabbani, Y.S. Babu, Charles E. Bugg, John E. Volanakis, Faisal Alqusaiyer	1991	4
15	A monoclonal antibody which blocks the function of factor D of human complement Journal of Immunological Methods ·Manuel Pascual, Yuanyuan Gao, François Spertini, Kevin Macon, John E. Volanakis, Jürg A. Schifferli	1990	22
16	Measurement of Complement Proteins C2 and B in Systemic Lupus erythematosus and Septic Shock PubMed ·T J Oglesby, D. R. Schultz, Roland M.H. Schein, Charles L. Sprung, John E. Volanakis	1989	2
17	Quantitative levels of C-reactive protein in cerebrospinal fluid in patients with bacterial meningitis and other conditions The Journal of Pediatrics ·Barry M. Gray, Søren Lüdeking, Mark Alten, Scott R. Barnum, John E. Volanakis	1986	31
18	Opsonic properties of C-reactive protein. Stimulation by phorbol myristate acetate enables human neutrophils to phagocytize C-reactive protein-coated cells. The Journal of Immunology ·J. Michael Kilpatrick, John E. Volanakis	1985	75
19	Cross-reactivity between C-reactive protein and idiotypic determinants on A phosphocholine-binding murine myeloma protein. The Journal of Experimental Medicine ·John E. Volanakis, John F. Kearney	1981	41
20	THE STRUCTURAL BASIS FOR BINDING OF COMPLEMENT BY IMMUNOGLOBULIN M The Journal of Experimental Medicine ·Zhanwu Li, John E. Volanakis, Raymond B. Hester, Robert M. Stroud, John Bennett	1974	26

About John E. Volanakis

John E. Volanakis is a scholar working on Hematology, Immunology, Genetics, Radiology, Nuclear Medicine and Imaging and Physiology, having authored 155 papers that have together received 9.1k indexed citations. Recurring topics across this work include Complement system in diseases (66 papers), Blood groups and transfusion (30 papers), Monoclonal and Polyclonal Antibodies Research (26 papers), Erythrocyte Function and Pathophysiology (24 papers), Blood Coagulation and Thrombosis Mechanisms (16 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (15 papers), Blood properties and coagulation (12 papers) and Iron Metabolism and Disorders (11 papers). The work is most often cited by research in Immunology (4.4k citations), Hematology (1.4k citations), Microbiology (474 citations), Epidemiology (2.3k citations) and Genetics (658 citations). John E. Volanakis has collaborated with scholars based in United States, Greece and United Kingdom. Frequent co-authors include Melvin H. Kaplan, Alexander J. Szalai, M. H. Kaplan, Sthanam V.L. Narayana, David E. Briles, Robert M. Stroud, Kevin Macon, Trevor J. Greenhough, J. Michael Kilpatrick and K.W.A. Wirtz. Their work appears in journals such as The Journal of Immunology, Molecular Immunology, Journal of Molecular Biology, Journal of Biological Chemistry and Journal of Immunological Methods.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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