Charles Kung

6.6k citations

50 papers · 3.7k indexed · 2 hit papers · h-index 20

Impact in

Hematology top 1%
- Erythropoietin and Anemia Treatment
Biochemistry top 1%
- Amino Acid Enzymes and Metabolism

Papers in

Hematology 21
- Erythropoietin and Anemia Treatment 9
- Blood groups and transfusion 9
Genetics 11
- Hemoglobinopathies and Related Disorders 11
- Blood disorders and treatments 5

Co-authors: Eugene Goldwasser Takahito Miyake Kevan M. Shokat Bailin Zhang Haidi Yang Beat Nyfeler Lewis C. Cantley Christopher J. Wilson
Journals: Blood (15 papers)Journal of Biological Chemistry (4 papers)Proceedings of the National Academy of Sciences (3 papers)Journal of Cellular Biochemistry (2 papers)Cell (2 papers)
Partner nations: United States Netherlands Canada

In The Last Decade

Charles Kung

49 papers receiving 3.6k citations

Hit Papers

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Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy 2009 · 1.4k citations

Peers

Countries citing papers authored by Charles Kung

Since Specialization

Citations

This map shows the geographic impact of Charles Kung's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles Kung with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles Kung more than expected).

Fields of papers citing papers by Charles Kung

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles Kung. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles Kung. The network helps show where Charles Kung may publish in the future.

Co-authors

The 25 scholars most cited alongside Charles Kung, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Charles Kung Line = papers co-authored together Charles Kung links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Preparation of Collagen Peptide Nanoliposomes From Sturgeon Fish Cartilage and Explore Their Anti‐Osteoarthritis Effects in Rats SHILAP Revista de lepidopterología ·Charles Kung, Mei‐Zhen Lin, Bing‐Huei Chen	2024	1
2	REM-422, a Small Molecule MYB mRNA Degrader, Demonstrates Anti-Leukemic Activity As Monotherapy and in Combination with Standards of Care in Preclinical Models of AML Blood ·G. A. Pleshchankov, Michael Thomas, Craig Cox, Rahil Mathakia, Alexander E. Ivliev, Adam Štefek, Michael D. Cameron, Sudeep Prajapati, Michael Seiler, Dominic J. Reynolds, Silvia Buonamici, Charles Kung	2024	1
3	Structure‐Based Design of AG‐946, a Pyruvate Kinase Activator ChemMedChem ·Shevchenko Se, Anil K. Padyana, 卓哉坂石, Lei Jin, Dalia I. Hammoudeh, Charles Kung, Lenny Dang	2023	5
4	AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes Haematologica ·Minke A.E. Rab, Brigitte A. van Oirschot, Penelope A. Kosinski, Jeffrey Hixon, Kendall Johnson, Victor Chubukov, Lenny Dang, Gerard Pasterkamp, Stephanie van Straaten, Wouter W. van Solinge, Eduard J. van Beers, Charles Kung, Richard van Wijk	2020	54
5	Decreased Activity and Stability of Pyruvate Kinase in Hereditary Hemolytic Anemia: A Potential Target for Therapy By AG-348 (Mitapivat), an Allosteric Activator of Red Blood Cell Pyruvate Kinase Blood ·Minke A.E. Rab, Brigitte A. van Oirschot, Stephanie van Straaten, Bart J. Biemond, 雄一木庭, Penelope A. Kosinski, Charles Kung, Eduard J. van Beers, Richard van Wijk	2019	12
6	Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production Cell Reports ·Brandon M. Gassaway, Rebecca Cardone, Anil K. Padyana, Max C. Petersen, 卓哉坂石, Sebastian Hayes, Shuilong Tong, Karl W. Barber, Hee Jong Song, Abudukadier Abulizi, U. K. Thianesh, Kshitiz Gupta, Hans R. Aerni, Stefan Größ, Charles Kung, Varman T. Samuel, Gerald I. Shulman, Richard G. Kibbey, Jesse Rinehart	2019	12
7	Results Update from the DRIVE PK Study: Effects of AG-348, a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency Blood ·Rachael F. Grace, D. Mark Layton, Frédéric Galactéros, Christian Rosé, Wilma Barcellini, D. Holmes Morton, Eduard J. van Beers, Hassan M. Yaish, Yaddanapudi Ravindranath, Kevin H.M. Kuo, Sujit Sheth, Janet L. Kwiatkowski, Bruce A. Silver, Charles Kung, Marvin B. Cohen, Hua Yang, Penelope A. Kosinski, Lei Hua, Ann Barbier, Bertil Glader	2017	2
8	A fit-for-purpose LC–MS/MS method for the simultaneous quantitation of ATP and 2,3-DPG in human K2EDTA whole blood Journal of Chromatography B ·Hyeryun Kim, Penelope A. Kosinski, Charles Kung, Lenny Dang, Yue Chen, Hua Yang, B. Addi, Patricia Galdon, Guowen Liu	2017	19
9	Safe and Efficient Gene Therapy for Pyruvate Kinase Deficiency Molecular Therapy ·Josip Kljajić, Andrea Calabria, María García‐Bravo, Fabrizio Benedicenti, Penelope A. Kosinski, Afif Ilham Saifudin, Collin Hill, María del Mar Mañú‐Pereira, Miguel A. Martı́n, Israel Orman, Joan‐Lluís Vives Corrons, Charles Kung, Axel Schambach, Shengfang Jin, Juan A. Bueren, Eugenio Montini, Susana Navarro, José C. Segovia	2016	43
10	Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy Cell ·Paul Nicklin, Philip J. Bergman, Bailin Zhang, Ellen Triantafellow, Celia Elizabeth Torres Robles, Beat Nyfeler, Haidi Yang, Marc Hild, Charles Kung, Christopher J. Wilson, Vic E. Myer, Jeffrey P. MacKeigan, Jeffrey A. Porter, CÉSAR GUAUQUE TORRES, Lewis C. Cantley, Peter M. Finan, Leon O. Murphy Hit paper breakdown →	2009	1369
11	Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis Proceedings of the National Academy of Sciences ·Elenita I. Kanin, Ryan Kipp, Charles Kung, Matthew Slattery, Agnès Viale, Steven Hahn, Kevan M. Shokat, Aseem Z. Ansari	2007	93
12	Structure-guided development of affinity probes for tyrosine kinases using chemical genetics Nature Chemical Biology ·Jimmy A. Blair, Daniel Rauh, Charles Kung, Cai‐Hong Yun, Qi-Wen Fan, Haridas B. Rode, Chao Zhang, Michael J. Eck, William A. Weiss, Kevan M. Shokat	2007	174
13	Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor Proceedings of the National Academy of Sciences ·Charles Kung, Denise M. Kenski, Scott H. Dickerson, Russell W. Howson, Lee F. Kuyper, Hiten D. Madhani, Kevan M. Shokat	2005	42
14	Small‐Molecule Kinase‐Inhibitor Target Assessment ChemBioChem ·Charles Kung, Kevan M. Shokat	2005	19
15	The F Box Protein Dsg1/Mdm30 Is a Transcriptional Coactivator that Stimulates Gal4 Turnover and Cotranscriptional mRNA Processing Cell ·Masafumi Muratani, Charles Kung, Kevan M. Shokat, William P. Tansey	2005	143
16	The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores Nature Cell Biology ·Benjamin A. Pinsky, Charles Kung, Kevan M. Shokat, Sue Biggins	2005	229
17	The Role of Tyrosine 15 in Erythropoietin Action Archives of Biochemistry and Biophysics ·Charles Kung, Li Fan, EUGENE GOLDWASSER	2000	2
18	Recent advances in lymphocyte signaling and regulation Frontiers in bioscience ·Charles Kung	1997	6
19	Receptor binding of asialoerythropoietin Journal of Cellular Biochemistry ·Carl Machin, Charles Kung, Eugene Goldwasser	1992	10
20	Characterization of erythropoietin receptors Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) ·P. Durgaiyya, Charles Kung, Eugene Goldwasser	1987	1

About Charles Kung

Charles Kung is a scholar working on Hematology, Genetics, Physiology, Cell Biology and Cancer Research, having authored 50 papers that have together received 3.7k indexed citations. Recurring topics across this work include Erythrocyte Function and Pathophysiology (22 papers), Hemoglobinopathies and Related Disorders (11 papers), Erythropoietin and Anemia Treatment (9 papers), Blood groups and transfusion (9 papers), Blood disorders and treatments (5 papers), Hemoglobin structure and function (5 papers), Neonatal Health and Biochemistry (4 papers) and Genomics and Chromatin Dynamics (4 papers). The work is most often cited by research in Hematology (948 citations), Biochemistry (368 citations), Genetics (390 citations), Cancer Research (522 citations) and Cell Biology (500 citations). Charles Kung has collaborated with scholars based in United States, Netherlands and Canada. Frequent co-authors include Eugene Goldwasser, Takahito Miyake, Kevan M. Shokat, Bailin Zhang, Haidi Yang, Beat Nyfeler, Lewis C. Cantley, Christopher J. Wilson, Jeffrey A. Porter and Jeffrey P. MacKeigan. Their work appears in journals such as Blood, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Journal of Cellular Biochemistry and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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