Bryant G. Darnay

8.3k total citations · 1 hit paper
65 papers, 6.9k citations indexed

About

Bryant G. Darnay is a scholar working on Molecular Biology, Cancer Research and Immunology. According to data from OpenAlex, Bryant G. Darnay has authored 65 papers receiving a total of 6.9k indexed citations (citations by other indexed papers that have themselves been cited), including 48 papers in Molecular Biology, 41 papers in Cancer Research and 27 papers in Immunology. Recurrent topics in Bryant G. Darnay's work include NF-κB Signaling Pathways (36 papers), Immune Response and Inflammation (18 papers) and interferon and immune responses (15 papers). Bryant G. Darnay is often cited by papers focused on NF-κB Signaling Pathways (36 papers), Immune Response and Inflammation (18 papers) and interferon and immune responses (15 papers). Bryant G. Darnay collaborates with scholars based in United States, United Kingdom and Australia. Bryant G. Darnay's co-authors include Bharat B. Aggarwal, Betty Lamothe, Alejandro D. Campos, Jian Ni, Paul A. Moore, Hao Wu, Xin Lin, Arnaud Besse, Sanjaya Singh and Valsala Haridas and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Bryant G. Darnay

65 papers receiving 6.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Distinct molecular mechanism for initiating TRAF6 signalling

2002 550 citations Betty Lamothe, Sujay Singh et al. profile →

Peers

Countries citing papers authored by Bryant G. Darnay

Since Specialization

Citations

This map shows the geographic impact of Bryant G. Darnay's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bryant G. Darnay with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bryant G. Darnay more than expected).

Fields of papers citing papers by Bryant G. Darnay

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bryant G. Darnay. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bryant G. Darnay. The network helps show where Bryant G. Darnay may publish in the future.

Co-authorship network of co-authors of Bryant G. Darnay

This figure shows the co-authorship network connecting the top 25 collaborators of Bryant G. Darnay. A scholar is included among the top collaborators of Bryant G. Darnay based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bryant G. Darnay. Bryant G. Darnay is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Regulation of TLR-triggered innate immune response by ubiquitin-specific protease 25 (180.8) 2012 ·The Journal of Immunology ·Bo Zhong, Xikui Liu, Xiaohu Wang, Xindong Liu, (unknown), Hongxiu Li, Bryant G. Darnay, Xin Lin, Shao‐Cong Sun, Dong Chen	1
2	Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and TGFβ-activated Kinase 1 (TAK1) Play Essential Roles in the C-type Lectin Receptor Signaling in Response to Candida albicans Infection 2012 ·Journal of Biological Chemistry ·Sara Gorjestani, Bryant G. Darnay, Xin Lin	23
3	Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice 2010 ·Proceedings of the National Academy of Sciences ·Xin Zhou, Zhaoping Zhang, Jian Q. Feng, V. Dusevich, Krishna M. Sinha, Hua Zhang, Bryant G. Darnay, Benoît De Crombrugghe	257
4	The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation 2009 ·Science ·Wei-Lei Yang, Jing Wang, Chia‐Hsin Chan, Szu-Wei Lee, Alejandro D. Campos, Betty Lamothe, (unknown), Brian C. Grabiner, Xin Lin, Bryant G. Darnay, Hui‐Kuan Lin	497
5	Dasatinib inhibits both osteoclast activation and prostate cancer PC-3 cell-induced osteoclast formation 2009 ·Cancer Biology & Therapy ·John C. Araujo, Ann T. Poblenz, Nila U. Parikh, Michael W. Starbuck, Jerry T. Thompson, Francis Lee, (unknown), Bryant G. Darnay	36
6	The RING Domain and First Zinc Finger of TRAF6 Coordinate Signaling by Interleukin-1, Lipopolysaccharide, and RANKL 2008 ·Journal of Biological Chemistry ·Betty Lamothe, Alejandro D. Campos, (unknown), (unknown), (unknown), Bryant G. Darnay	98
7	Cthrc1 Is a Positive Regulator of Osteoblastic Bone Formation 2008 ·PLoS ONE ·Hiroaki Kimura, Kin Ming Kwan, Zhaoping Zhang, Jian Min Deng, Bryant G. Darnay, Richard R. Behringer, Takashi Nakamura, Benoît De Crombrugghe, Haruhiko Akiyama	88
8	Inhibition of RANKL-mediated osteoclast differentiation by selective TRAF6 decoy peptides 2007 ·Biochemical and Biophysical Research Communications ·Ann T. Poblenz, (unknown), Sujay Singh, Bryant G. Darnay	26
9	Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20 2007 ·Journal of Molecular Biology ·Su‐Chang Lin, Jee Young Chung, Betty Lamothe, Kanagalaghatta R. Rajashankar, Miao Lu, Yu-Chih Lo, (unknown), Bryant G. Darnay, Hao Wu	133
10	TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation 2007 ·Biochemical and Biophysical Research Communications ·Betty Lamothe, (unknown), (unknown), Arnaud Besse, Alejandro D. Campos, Bryant G. Darnay	111
11	Nuclear Tumor Necrosis Factor Receptor-associated Factor 6 in Lymphoid Cells Negatively Regulates c-Myb-mediated Transactivation through Small Ubiquitin-related Modifier-1 Modification 2007 ·Journal of Biological Chemistry ·Lan V. Pham, Haijun Zhou, Yen-Chiu Lin-Lee, Archito T. Tamayo, Linda C. Yoshimura, Lingchen Fu, Bryant G. Darnay, R. Ford	24
12	CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-κB activation 2007 ·Genes & Development ·Brian C. Grabiner, Marzenna Blonska, (unknown), Yun You, Donghai Wang, (unknown), Bryant G. Darnay, Chen Dong, Xin Lin	106
13	Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent VEGF121/rGel 2006 ·Cancer Research ·Khalid A. Mohamedali, Ann T. Poblenz, Charles R. Sikes, Nora M. Navone, Philip E. Thorpe, Bryant G. Darnay, Michael G. Rosenblum	25
14	Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation 2006 ·Journal of Biological Chemistry ·Betty Lamothe, Arnaud Besse, Alejandro D. Campos, (unknown), Hao Wu, Bryant G. Darnay	308
15	TWEAK Mediates Signal Transduction and Differentiation of RAW264.7 Cells in the Absence of Fn14/TweakR 2003 ·Journal of Biological Chemistry ·Tara C. Polek, Moshe Talpaz, Bryant G. Darnay, Taly R. Spivak-Kroizman	129
16	Activation of NF-κB by RANK Requires Tumor Necrosis Factor Receptor-associated Factor (TRAF) 6 and NF-κB-inducing Kinase 1999 ·Journal of Biological Chemistry ·Bryant G. Darnay, Jian Ni, Paul A. Moore, Bharat B. Aggarwal	344
17	Inhibition of protein tyrosine phosphatases causes phosphorylation of tyrosine‐331 in the p60 TNF receptor and inactivates the receptor‐associated kinase 1997 ·FEBS Letters ·Bryant G. Darnay, Bharat B. Aggarwal	15
18	Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF-κB Activation, IκBα Phosphorylation, and Degradation 1997 ·Journal of Biological Chemistry ·Madan M. Chaturvedi, Ashok Kumar, Bryant G. Darnay, G.B.N. Chainy, Sudha Agarwal, Bharat B. Aggarwal	255
19	Site-specific Tyrosine Phosphorylation of IκBα Negatively Regulates Its Inducible Phosphorylation and Degradation 1996 ·Journal of Biological Chemistry ·Sanjaya Singh, Bryant G. Darnay, Bharat B. Aggarwal	113
20	The p60 Tumor Necrosis Factor (TNF) Receptor-associated Kinase (TRAK) Binds Residues 344–397 within the Cytoplasmic Domain Involved in TNF Signaling 1995 ·Journal of Biological Chemistry ·Bryant G. Darnay, Sanjaya Singh, Madan M. Chaturvedi, Bharat B. Aggarwal	214

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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