Changxian Shen

1.7k total citations
38 papers, 1.2k citations indexed

About

Changxian Shen is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Changxian Shen has authored 38 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 30 papers in Molecular Biology, 11 papers in Oncology and 6 papers in Cancer Research. Recurrent topics in Changxian Shen's work include DNA Repair Mechanisms (13 papers), RNA Interference and Gene Delivery (7 papers) and Advanced biosensing and bioanalysis techniques (6 papers). Changxian Shen is often cited by papers focused on DNA Repair Mechanisms (13 papers), RNA Interference and Gene Delivery (7 papers) and Advanced biosensing and bioanalysis techniques (6 papers). Changxian Shen collaborates with scholars based in United States, Germany and China. Changxian Shen's co-authors include Sven N. Reske, Andreas K. Buck, Peter J. Houghton, Holger Schirrmeister, Michael Winkler, Xiangwei Liu, Torsten Mattfeldt, Gerhard Glatting, Thorsten Kühn and Jörg Kotzerke and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Molecular and Cellular Biology.

In The Last Decade

Changxian Shen

37 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Changxian Shen United States 17 684 296 288 286 167 38 1.2k
Andrea Rosner United States 12 569 0.8× 341 1.2× 310 1.1× 122 0.4× 118 0.7× 16 929
Patrick Maier Germany 16 417 0.6× 263 0.9× 154 0.5× 139 0.5× 140 0.8× 31 889
Brian C.‐S. Liu United States 20 635 0.9× 194 0.7× 191 0.7× 125 0.4× 174 1.0× 44 1.3k
G Boxer United Kingdom 20 563 0.8× 309 1.0× 134 0.5× 579 2.0× 110 0.7× 41 1.2k
Shelly Gunn United States 12 445 0.7× 298 1.0× 162 0.6× 95 0.3× 91 0.5× 28 814
Julia V. Burnier Canada 21 592 0.9× 408 1.4× 318 1.1× 82 0.3× 123 0.7× 73 1.2k
Ani Arakelian Canada 21 747 1.1× 361 1.2× 332 1.2× 62 0.2× 162 1.0× 30 1.1k
Ainura Kyshtoobayeva United States 13 441 0.6× 420 1.4× 192 0.7× 169 0.6× 95 0.6× 18 859
Fan Mo Canada 19 667 1.0× 320 1.1× 521 1.8× 136 0.5× 598 3.6× 29 1.3k
Ecaterina E. Dumbrava United States 17 379 0.6× 647 2.2× 194 0.7× 171 0.6× 218 1.3× 115 1.0k

Countries citing papers authored by Changxian Shen

Since Specialization
Citations

This map shows the geographic impact of Changxian Shen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Changxian Shen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Changxian Shen more than expected).

Fields of papers citing papers by Changxian Shen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Changxian Shen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Changxian Shen. The network helps show where Changxian Shen may publish in the future.

Co-authorship network of co-authors of Changxian Shen

This figure shows the co-authorship network connecting the top 25 collaborators of Changxian Shen. A scholar is included among the top collaborators of Changxian Shen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Changxian Shen. Changxian Shen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Wang, Yixing, Chen Wang, Jennifer Jossart, et al.. (2025). Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy. ACS Chemical Biology. 20(6). 1258–1272.
2.
Shen, Changxian, Tiantian Cui, Linlin Yang, et al.. (2025). KRAS-induced STN1 (OBFC1) promotes proper CTC1–STN1–TEN1 complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer. Nucleic Acids Research. 53(18). 1 indexed citations
3.
Shen, Changxian, Yanfei Wu, Jiaqi Tu, et al.. (2025). Deep learning-based tumor segmentation and radiogenomic model for predicting EGFR amplification and assessing intratumoural heterogeneity in glioblastoma. Journal Of Big Data. 12(1). 1 indexed citations
4.
Wolfe, Adam R., et al.. (2024). RAS-RAF-miR-296-3p signaling axis increases Rad18 expression to augment radioresistance in pancreatic and thyroid cancers. Cancer Letters. 591. 216873–216873. 2 indexed citations
5.
Sebastian, Nikhil, Amy Webb, Konstantin Shilo, et al.. (2023). A PI3K gene expression signature predicts for recurrence in early‐stage non–small cell lung cancer treated with stereotactic body radiation therapy. Cancer. 129(24). 3971–3977. 3 indexed citations
6.
Castro-Aceituno, Verónica, Linlin Yang, Sindhu Nair, et al.. (2023). Inhibition of RRM2 radiosensitizes glioblastoma and uncovers synthetic lethality in combination with targeting CHK1. Cancer Letters. 570. 216308–216308. 12 indexed citations
8.
Yang, Linlin, Changxian Shen, Adriana Estrada‐Bernal, et al.. (2021). Oncogenic KRAS drives radioresistance through upregulation of NRF2-53BP1-mediated non-homologous end-joining repair. Nucleic Acids Research. 49(19). 11067–11082. 48 indexed citations
9.
Houghton, Peter J., et al.. (2021). Regulation of DNA duplication by the mTOR signaling pathway. Cell Cycle. 20(8). 742–751. 11 indexed citations
10.
Yang, Linlin, Changxian Shen, Tianyun Li, et al.. (2020). Wee1 Kinase Inhibitor AZD1775 Effectively Sensitizes Esophageal Cancer to Radiotherapy. Clinical Cancer Research. 26(14). 3740–3750. 38 indexed citations
11.
Robb, Ryan, Linlin Yang, Changxian Shen, et al.. (2019). Inhibiting BRAF Oncogene–Mediated Radioresistance Effectively Radiosensitizes BRAFV600E-Mutant Thyroid Cancer Cells by Constraining DNA Double-Strand Break Repair. Clinical Cancer Research. 25(15). 4749–4760. 39 indexed citations
12.
Yang, Linlin, Bhavna Kumar, Changxian Shen, et al.. (2019). LCL161, a SMAC-mimetic, Preferentially Radiosensitizes Human Papillomavirus–negative Head and Neck Squamous Cell Carcinoma. Molecular Cancer Therapeutics. 18(6). 1025–1035. 26 indexed citations
13.
Bill, Marius, Malith Karunasiri, Changxian Shen, et al.. (2019). EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia. Clinical Cancer Research. 26(3). 669–678. 20 indexed citations
14.
Singh, Mamata, Brian Geier, Wenrui Duan, et al.. (2014). FANCD2 Is a Potential Therapeutic Target and Biomarker in Alveolar Rhabdomyosarcoma Harboring the PAX3–FOXO1 Fusion Gene. Clinical Cancer Research. 20(14). 3884–3895. 11 indexed citations
15.
Shen, Changxian, Doris A. Phelps, Hakan Çam, et al.. (2013). Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks. Cancer Research. 73(11). 3393–3401. 74 indexed citations
16.
Shen, Changxian, Cynthia S. Lancaster, Bin Shi, et al.. (2007). TOR Signaling Is a Determinant of Cell Survival in Response to DNA Damage. Molecular and Cellular Biology. 27(20). 7007–7017. 75 indexed citations
17.
Shen, Changxian & Sven N. Reske. (2004). Adenovirus-Delivered siRNA. Humana Press eBooks. 252. 523–532. 18 indexed citations
18.
Shen, Changxian, Dirk Rattat, Andreas K. Buck, et al.. (2003). Targeting bcl-2 by Triplex-Forming Oligonucleotide—A Promising Carrier for Gene–Radiotherapy. Cancer Biotherapy and Radiopharmaceuticals. 18(1). 17–26. 16 indexed citations
19.
Shen, Changxian, Andreas K. Buck, Bülent Polat, et al.. (2003). Triplex-forming oligodeoxynucleotides targeting survivin inhibit proliferation and induce apoptosis of human lung carcinoma cells. Cancer Gene Therapy. 10(5). 403–410. 33 indexed citations
20.
Shen, Changxian, Holger Schirrmeister, Alexandra Schmid‐Kotsas, et al.. (2002). Liposomal Delivery of Antisense Oligonucleotides for Efficient Downregulation of Bcl-2 and Induction of Apoptosis. Cancer Biotherapy and Radiopharmaceuticals. 17(3). 281–289. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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