Mutsuo Sekiguchi

9.0k total citations · 1 hit paper
175 papers, 7.7k citations indexed

About

Mutsuo Sekiguchi is a scholar working on Molecular Biology, Genetics and Cancer Research. According to data from OpenAlex, Mutsuo Sekiguchi has authored 175 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 162 papers in Molecular Biology, 50 papers in Genetics and 30 papers in Cancer Research. Recurrent topics in Mutsuo Sekiguchi's work include DNA Repair Mechanisms (105 papers), DNA and Nucleic Acid Chemistry (45 papers) and Bacterial Genetics and Biotechnology (42 papers). Mutsuo Sekiguchi is often cited by papers focused on DNA Repair Mechanisms (105 papers), DNA and Nucleic Acid Chemistry (45 papers) and Bacterial Genetics and Biotechnology (42 papers). Mutsuo Sekiguchi collaborates with scholars based in Japan, China and United States. Mutsuo Sekiguchi's co-authors include Hisaji Maki, Hiroshi Hayakawa, Yusaku Nakabeppu, Teruhisa Tsuzuki, Kunihiko Sakumi, Seiichi Yasuda, Yasuyuki Takagi, Tatsurou Tajiri, Seymour S. Cohen and Takashi Horiuchi and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Mutsuo Sekiguchi

175 papers receiving 7.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

1992 764 citations Hisaji Maki, Mutsuo Sekiguchi profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mutsuo Sekiguchi Japan	48	6.6k	1.7k	1.5k	647	594	175	7.7k
Susan S. Wallace United States	57	8.9k 1.3×	1.3k 0.8×	2.1k 1.3×	1.1k 1.6×	424 0.7×	195	10.0k
Geir Slupphaug Norway	44	7.7k 1.2×	1.0k 0.6×	1.2k 0.8×	1.2k 1.9×	388 0.7×	120	9.6k
Serge Boiteux France	46	6.1k 0.9×	856 0.5×	1.8k 1.2×	690 1.1×	127 0.2×	90	6.8k
Richard P. Cunningham United States	46	6.8k 1.0×	1.7k 1.0×	738 0.5×	636 1.0×	566 1.0×	104	7.7k
Stuart Rudikoff United States	48	5.1k 0.8×	936 0.5×	803 0.5×	1.2k 1.9×	139 0.2×	133	9.3k
Yoshiyuki Kuchino Japan	39	4.8k 0.7×	427 0.2×	816 0.5×	786 1.2×	186 0.3×	132	6.2k
Michael M. Seidman United States	48	6.0k 0.9×	888 0.5×	1.2k 0.8×	998 1.5×	265 0.4×	147	6.8k
Carmelo B. Bruni Italy	42	3.5k 0.5×	1.5k 0.9×	311 0.2×	317 0.5×	392 0.7×	127	5.4k
Samson T. Jacob United States	51	8.2k 1.2×	628 0.4×	4.0k 2.6×	969 1.5×	90 0.2×	195	11.0k
B.A. Bridges United Kingdom	42	4.6k 0.7×	1.4k 0.8×	2.3k 1.5×	592 0.9×	204 0.3×	208	6.6k

Countries citing papers authored by Mutsuo Sekiguchi

Since Specialization

Citations

This map shows the geographic impact of Mutsuo Sekiguchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mutsuo Sekiguchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mutsuo Sekiguchi more than expected).

Fields of papers citing papers by Mutsuo Sekiguchi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mutsuo Sekiguchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mutsuo Sekiguchi. The network helps show where Mutsuo Sekiguchi may publish in the future.

Co-authorship network of co-authors of Mutsuo Sekiguchi

This figure shows the co-authorship network connecting the top 25 collaborators of Mutsuo Sekiguchi. A scholar is included among the top collaborators of Mutsuo Sekiguchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mutsuo Sekiguchi. Mutsuo Sekiguchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ishii, Takashi, et al.. (2020). PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions. Journal of Biological Chemistry. 295(34). 12247–12261. 32 indexed citations

Ishii, Takashi & Mutsuo Sekiguchi. (2019). Two ways of escaping from oxidative RNA damage: Selective degradation and cell death. DNA repair. 81. 102666–102666. 33 indexed citations

Ishii, Takashi, Hiroshi Hayakawa, Takeshi Sekiguchi, Noritaka Adachi, & Mutsuo Sekiguchi. (2014). Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells. Free Radical Biology and Medicine. 79. 109–116. 42 indexed citations

Shi, Fei, Wei Gan, Ben Nie, et al.. (2012). Greater nucleic acids oxidation in the temporal lobe than the frontal lobe in SAMP8. Neuroreport. 23(8). 508–512. 1 indexed citations

Gan, Wei, Ben Nie, Fei Shi, et al.. (2012). Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC–MS/MS: Urinary 8-oxoguanosine as a novel biomarker of aging. Free Radical Biology and Medicine. 52(9). 1700–1707. 80 indexed citations

Zhang, Liqun, Dongge Liu, Jing Lin, et al.. (2011). Oxidative Damage to RNA and Expression Patterns of MTH1 in the Hippocampi of Senescence-Accelerated SAMP8 Mice and Alzheimer’s Disease Patients. Neurochemical Research. 36(8). 1558–1565. 32 indexed citations

Setoyama, Daiki, et al.. (2010). Molecular actions of Escherichia coli MutT for control of spontaneous mutagenesis. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 707(1-2). 9–14. 19 indexed citations

Yamazaki, Jun, Toshihiro Horii, Mutsuo Sekiguchi, & Masayuki Takahashi. (2003). Regulation of RecA Protein Binding to DNA by Opposing Effects of ATP and ADP on Inter-domain Contacts: Analysis by Urea-induced Unfolding of Wild-type and C-terminal Truncated RecA. Journal of Molecular Biology. 329(2). 363–370. 7 indexed citations

Takagi, Yasumitsu, et al.. (2003). Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis. DNA repair. 2(10). 1135–1146. 38 indexed citations

10.

Kitajima, Yoshihiko, Kohji Miyazaki, Shiroh Matsukura, Masayuki Tanaka, & Mutsuo Sekiguchi. (2003). Loss of expression of DNA repair enzymes MGMT, hMLH1, and hMSH2 during tumor progression in gastric cancer. Gastric Cancer. 6(2). 86–95. 34 indexed citations

11.

Reese, Jane, et al.. (2001). MGMT Expression in Murine Bone Marrow Is a Major Determinant of Animal Survival After Alkylating Agent Exposure. Journal of Hematotherapy & Stem Cell Research. 10(1). 115–123. 18 indexed citations

12.

Ishikawa, Takatoshi, Fumio Ide, Xiusheng Qin, et al.. (2001). Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 477(1-2). 41–49. 27 indexed citations

13.

Inoüe, Ryo, Masako Abe, Yusaku Nakabeppu, et al.. (2000). Characterization of human polymorphic DNA repair methyltransferase. Pharmacogenetics. 10(1). 59–66. 48 indexed citations

14.

Tsuzuki, Teruhisa, Kunihiko Sakumi, Hisaya Kawate, et al.. (1996). ACCELERATED PAPER: Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent. Carcinogenesis. 17(6). 1215–1220. 103 indexed citations

15.

Kawate, Hisaya, Kenji Ihara, Kohfuku Kohda, Kunihiko Sakumi, & Mutsuo Sekiguchi. (1995). Mouse methyltransferase for repair of O⁶-methylguanine and O⁴-methylthymine in DNA. Carcinogenesis. 16(7). 1595–1602. 25 indexed citations

16.

Nakamura, Takanori, et al.. (1994). Roles of transcription and repair in alkylation mutagenesis. Mutation Research/DNA Repair. 314(3). 273–285. 42 indexed citations

17.

Belguise-Valladier, Pascale, Hisaji Maki, Mutsuo Sekiguchi, & Robert P. Fuchs. (1994). Effect of Single DNA Lesions on in Vitro Replication with DNA Polymerase III Holoenzyme. Journal of Molecular Biology. 236(1). 151–164. 68 indexed citations

18.

Suzuki, Makoto, Kazuhiko Takahashi, Yutaka Kawazoe, Kunihiko Sakumi, & Mutsuo Sekiguchi. (1991). Inhibitory effect of cadmium and mercury ions on transcription of the ada gene. Biochemical and Biophysical Research Communications. 179(3). 1517–1521. 4 indexed citations

19.

Takano, Kyoko, Yusaku Nakabeppu, & Mutsuo Sekiguchi. (1988). Functional sites of the Ada regulatory protein of Escherichia coli. Journal of Molecular Biology. 201(2). 261–271. 49 indexed citations

20.

Tokumoto, Yasuhito, et al.. (1988). Expression of the ada gene of Escherichia coli in response to alkylating agents. Journal of Molecular Biology. 202(3). 483–494. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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