Bernhard Lüscher

20.5k citations

191 papers · 14.4k indexed · 3 hit papers · h-index 68

Impact in

Physiology top 0.1%
Geriatrics and Gerontology top 0.2%

Papers in

Physiology 19
Oncology 80
- PARP inhibition in cancer therapy 46
- Cancer-related Molecular Pathways 28

Co-authors: Robert N. Eisenman Juliane Lüscher‐Firzlaff Marie Arsenian‐Henriksson Jörg Vervoorts David W. Litchfield Michael O. Hottiger R N Eisenman Paul O. Hassa
Journals: Scientific Reports (10 papers)Journal of Biological Chemistry (9 papers)Oncogene (9 papers)Molecular and Cellular Biology (9 papers)Current topics in microbiology and immunology (5 papers)
Partner nations: Germany United States Switzerland

In The Last Decade

Bernhard Lüscher

189 papers receiving 14.2k citations

Hit Papers

align trajectories log scale

Toward a unified nomenclature for mammalian ADP-ribosyltransferases 2010 · 686 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Trends in Biochemical Sciences
1996 Advances in cancer research
1990 Nature

Peers

Countries citing papers authored by Bernhard Lüscher

Since Specialization

Citations

This map shows the geographic impact of Bernhard Lüscher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bernhard Lüscher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bernhard Lüscher more than expected).

Fields of papers citing papers by Bernhard Lüscher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bernhard Lüscher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bernhard Lüscher. The network helps show where Bernhard Lüscher may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Bernhard Lüscher, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bernhard Lüscher Line = papers co-authored together Bernhard Lüscher links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells Molecular Oncology ·Jörg Zirfas, Freddy Íñiguez, А.С. Соловьева, Geoffroy Andrieux, Christian Preisinger, 裵錫連, Ir. Maria Freire da Silva, Melanie Boerries, Kerstin Becker, Ruth Knüchel, 中山慎太郎, Bernhard Lüscher	2025	1
2	Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication Cellular and Molecular Life Sciences ·Sarah Krieg, Fabian Pott, Petar Vrankić, Khalide Jbilou, Mareike Bütepage, Ir. Maria Freire da Silva, Barbara E. Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn	2023	18
3	[1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes Journal of Medicinal Chemistry ·عادل المكينزي, Cheng Qun Wu, Mirko M. Maksimainen, Serena Massari, Виктор Тайдаков, Barbara E. Lippok, Silvina M Juarez, Sven T. Sowa, Albert Galera‐Prat, Tasneem Sarwar, Harikanth Venkannagari, Renata Prunskaite‐Hyyryläinen, Elena Dreassi, Bernhard Lüscher, Patricia Korn, Oriana Tabarrini, L. Lehtiö	2023	15
4	Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L Scientific Reports ·Е. А. Ананьева, اشرف حیدر ابو الفتوح, Óscar Sánchez-Meneses, Duchmann Jc, Juliane Lüscher‐Firzlaff, Bernhard Lüscher	2023	2
5	Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes Nucleic Acids Research ·Taciana Rocha dos Santos Sixel, Óscar Sánchez-Meneses, اشرف حیدر ابو الفتوح, Chao‐Chung Kuo, Е. А. Ананьева, 三郎中辻, Duchmann Jc, Ivan G. Costa, Juliane Lüscher‐Firzlaff, Bernhard Lüscher	2022	7
6	Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15 European Journal of Medicinal Chemistry ·Cheng Qun Wu, Mirko M. Maksimainen, عادل المكينزي, Serena Massari, Виктор Тайдаков, Barbara E. Lippok, Sven T. Sowa, Albert Galera‐Prat, Renata Prunskaite‐Hyyryläinen, Bernhard Lüscher, Patricia Korn, L. Lehtiö, Oriana Tabarrini	2022	7
7	Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters Scientific Reports ·Е. А. Ананьева, Óscar Sánchez-Meneses, Taciana Rocha dos Santos Sixel, Chao‐Chung Kuo, Carlos Cassemiro Casaril, اشرف حیدر ابو الفتوح, Duchmann Jc, Juliane Lüscher‐Firzlaff, Ivan G. Costa, Bernhard Lüscher	2022	7
8	Enhanced Sampling Approach to the Induced-Fit Docking Problem in Protein–Ligand Binding: The Case of Mono-ADP-Ribosylation Hydrolase Inhibitors Journal of Chemical Theory and Computation ·Qianqian Zhao, Riccardo Capelli, Paolo Carloni, Bernhard Lüscher, Jinyu Li, Giulia Rossetti	2021	17
9	The search for inhibitors of macrodomains for targeting the readers and erasers of mono-ADP-ribosylation Drug Discovery Today ·Wei Fu, Keerati Suppatkul, Mareike Bütepage, Qianqian Zhao, Bernhard Lüscher, Jinyu Li	2021	11
10	Evaluation of 3‐ and 4‐Phenoxybenzamides as Selective Inhibitors of the Mono‐ADP‐Ribosyltransferase PARP10 ChemistryOpen ·Patricia Korn, Arno Claßen, عادل المكينزي, 安莹, Mirko M. Maksimainen, Barbara E. Lippok, Albert Galera‐Prat, Sven T. Sowa, Andrew Dholichand, Giulia Rossetti, L. Lehtiö, Carsten Bolm, Bernhard Lüscher	2021	10
11	ADP-ribosylation of RNA and DNA: fromin vitrocharacterization toin vivofunction Nucleic Acids Research ·G De Bock, H. Goujon, Tatiana Oklander, Bernhard Lüscher, Karla L. H. Feijs, Roko Žaja	2021	66
12	AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy Nature Communications ·Marc Dohmen, Sarah Krieg, Taenam Moon, Xiaoqing Zhu, Noriaki Set, Oğuz Şimşek, R.O. Marsh, Mareike Bütepage, AshaO Reddy, 宁书贤, Dipanjan Chanda, Stephan Geley, Christian Preisinger, Kei Sakamoto, Bernhard Lüscher, Dietbert Neumann, Jörg Vervoorts	2020	30
13	Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription Scientific Reports ·Mareike Bütepage, Christian Preisinger, Alex von Kriegsheim, Raymond Tsai, Samantha Ovens, Jinyu Li, Ferdinand Kappes, Regina Feederle, Theodor N. Fleidner, Laura Eckei, Sarah Krieg, Gerhard Müller‐Newen, Giulia Rossetti, Karla L. H. Feijs, Patricia Verheugd, Bernhard Lüscher	2018	37
14	4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10 European Journal of Medicinal Chemistry ·عادل المكينزي, Jenny Desantis, Patricia Verheugd, Mirko M. Maksimainen, Harikanth Venkannagari, Serena Massari, Tasneem Sarwar, Ezeogo Obaji, María Pilar Viña Gómez, Bernhard Lüscher, Oriana Tabarrini, L. Lehtiö	2018	25
15	Control of the Physical and Antimicrobial Skin Barrier by an IL-31–IL-1 Signaling Network The Journal of Immunology ·Diego Andrés Castro-López, 宁书贤, Christian Cornelissen, Philipp M. Amann, Yvonne Marquardt, Katharina Czaja, Arianna L. Kim, Bernhard Lüscher, Jens Malte Baron	2016	56
16	Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30 II accessory protein and the induction of oncogenic cellular transformation by p30 II /c-MYC Virology ·Ulysses Byas, Bookyung Ko, Janice Kim, 松山義人, Nicolas Barillat, Jeffrey He, Itsuo Miyazaki, David H. Lont, Lee Ratner, Michael D. Lairmore, Ernest Martinez, Bernhard Lüscher, Craig Robson, Marie Arsenian‐Henriksson, Robert Harrod	2015	15
17	Regulation of the NAD + -dependent deacetylase SIRT2 by CDK5 RWTH Publications (RWTH Aachen) ·Я.С. Фрейдзон, Bernhard Lüscher	2012	1
18	Characterization of the mono-ADP-ribosylation by ARTD10 : substrates, consequences and reversibility RWTH Publications (RWTH Aachen) ·Karla L. H. Feijs, Bernhard Lüscher	2012	1
19	Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1 Biochemical Journal ·Anja Krippner‐Heidenreich, Robert V. Talanian, Renate Sekul, Regine Kraft, Hubert Thole, W. Zhang, Bernhard Lüscher	2001	93
20	C/EBP, c-Myb, and PU.1 Cooperate To Regulate the Neutrophil Elastase Promoter Molecular and Cellular Biology ·Michael Oelgeschläger, Issarang Nuchprayoon, Bernhard Lüscher, Alan D. Friedman	1996	207

About Bernhard Lüscher

Bernhard Lüscher is a scholar working on Physiology, Oncology, Immunology, Geriatrics and Gerontology and Molecular Biology, having authored 191 papers that have together received 14.4k indexed citations. Recurring topics across this work include PARP inhibition in cancer therapy (46 papers), Toxin Mechanisms and Immunotoxins (34 papers), Cancer-related Molecular Pathways (28 papers), Genomics and Chromatin Dynamics (26 papers), Protein Kinase Regulation and GTPase Signaling (20 papers), Cell death mechanisms and regulation (20 papers), Epigenetics and DNA Methylation (20 papers) and Ubiquitin and proteasome pathways (19 papers). The work is most often cited by research in Physiology (1.0k citations), Geriatrics and Gerontology (767 citations), Oncology (4.9k citations), Immunology (3.0k citations) and Molecular Biology (9.1k citations). Bernhard Lüscher has collaborated with scholars based in Germany, United States and Switzerland. Frequent co-authors include Robert N. Eisenman, Juliane Lüscher‐Firzlaff, Marie Arsenian‐Henriksson, Jörg Vervoorts, David W. Litchfield, Michael O. Hottiger, R N Eisenman, Paul O. Hassa, Patricia Verheugd and Jens Malte Baron. Their work appears in journals such as Scientific Reports, Journal of Biological Chemistry, Oncogene, Molecular and Cellular Biology and Current topics in microbiology and immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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