Alan D. Borthwick

3.1k total citations · 1 hit paper
52 papers, 2.2k citations indexed

About

Alan D. Borthwick is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Alan D. Borthwick has authored 52 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Organic Chemistry, 25 papers in Molecular Biology and 13 papers in Infectious Diseases. Recurrent topics in Alan D. Borthwick's work include HIV/AIDS drug development and treatment (12 papers), Biochemical and Molecular Research (10 papers) and Carbohydrate Chemistry and Synthesis (8 papers). Alan D. Borthwick is often cited by papers focused on HIV/AIDS drug development and treatment (12 papers), Biochemical and Molecular Research (10 papers) and Carbohydrate Chemistry and Synthesis (8 papers). Alan D. Borthwick collaborates with scholars based in United Kingdom, United States and Germany. Alan D. Borthwick's co-authors include Keith Biggadike, Anne M. Exall, Terry Haley, Barrie E. Kirk, Stanley M. Roberts, Gordon G. Weingarten, John Liddle, Stephen Caddick, Philip J. Parsons and Graham Hart and has published in prestigious journals such as Chemical Reviews, Journal of Medicinal Chemistry and Tetrahedron.

In The Last Decade

Alan D. Borthwick

51 papers receiving 2.1k citations

Hit Papers

2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Ch... 2012 2026 2016 2021 2012 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. 2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products
    2012 700 citations Alan D. Borthwick profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alan D. Borthwick United Kingdom 23 1.3k 1.1k 385 330 200 52 2.2k
Mark Cushman United States 35 1.3k 1.1× 1.8k 1.7× 466 1.2× 463 1.4× 251 1.3× 120 3.5k
Kenichi Akaji Japan 32 1.3k 1.0× 2.2k 2.0× 506 1.3× 184 0.6× 118 0.6× 188 3.4k
Satoshi Ichikawa Japan 32 1.8k 1.4× 2.0k 1.8× 246 0.6× 610 1.8× 109 0.5× 155 3.3k
Daniel Bur Switzerland 32 1.0k 0.8× 1.5k 1.3× 161 0.4× 138 0.4× 95 0.5× 88 2.9k
Lise‐Lotte Gundersen Norway 31 2.3k 1.8× 848 0.8× 486 1.3× 253 0.8× 202 1.0× 104 2.9k
Sandra Gemma Italy 35 1.3k 1.0× 1.4k 1.3× 296 0.8× 723 2.2× 257 1.3× 132 3.4k
MAKI NISHIO Japan 27 822 0.6× 1.0k 1.0× 136 0.4× 612 1.9× 169 0.8× 83 2.2k
Robert J. Suhadolnik United States 31 868 0.7× 2.2k 2.0× 537 1.4× 505 1.5× 326 1.6× 169 3.6k
Fumiaki Yokokawa Japan 29 908 0.7× 719 0.7× 412 1.1× 330 1.0× 85 0.4× 63 2.2k
Gyula Batta Hungary 29 1.1k 0.9× 1.6k 1.4× 222 0.6× 337 1.0× 132 0.7× 194 3.0k

Countries citing papers authored by Alan D. Borthwick

Since Specialization
Citations

This map shows the geographic impact of Alan D. Borthwick's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan D. Borthwick with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan D. Borthwick more than expected).

Fields of papers citing papers by Alan D. Borthwick

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan D. Borthwick. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan D. Borthwick. The network helps show where Alan D. Borthwick may publish in the future.

Co-authorship network of co-authors of Alan D. Borthwick

This figure shows the co-authorship network connecting the top 25 collaborators of Alan D. Borthwick. A scholar is included among the top collaborators of Alan D. Borthwick based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alan D. Borthwick. Alan D. Borthwick is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Borthwick, Alan D., Carlos Alemparte, Ian D. Wall, et al.. (2020). Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo Activity. Journal of Medicinal Chemistry. 63(5). 2557–2576. 28 indexed citations
2.
Borthwick, Alan D., Maria B. Goncalves, & Jonathan Corcoran. (2020). Recent advances in the design of RAR α and RAR β agonists as orally bioavailable drugs. A review. Bioorganic & Medicinal Chemistry. 28(20). 115664–115664. 17 indexed citations
3.
Goncalves, Maria B., Earl E. Clarke, Christopher I Jarvis, et al.. (2019). Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury. Bioorganic & Medicinal Chemistry Letters. 29(8). 995–1000. 5 indexed citations
4.
Clarke, Earl E., Christopher I Jarvis, Maria B. Goncalves, et al.. (2017). Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist. Bioorganic & Medicinal Chemistry. 26(4). 798–814. 9 indexed citations
5.
Borthwick, Alan D.. (2017). Fluparoxan: A Comprehensive Review of its Discovery, Adrenergic and CNS Activity and Treatment of Cognitive Dysfunction in Central Neurodegenerative Diseases. Mini-Reviews in Medicinal Chemistry. 17(7). 572–582. 2 indexed citations
6.
Borthwick, Alan D., Nicolas Ancellin, Sophie M. Bertrand, et al.. (2016). Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening. Journal of Medicinal Chemistry. 59(6). 2452–2467. 27 indexed citations
7.
Borthwick, Alan D., et al.. (2015). 2,5-diketopiperazines in food and beverages: Taste and bioactivity. Critical Reviews in Food Science and Nutrition. 57(4). 718–742. 67 indexed citations
8.
Borthwick, Alan D., John Liddle, Anne M. Exall, et al.. (2012). Pyridyl-2,5-Diketopiperazines as Potent, Selective, and Orally Bioavailable Oxytocin Antagonists: Synthesis, Pharmacokinetics, and In Vivo Potency. Journal of Medicinal Chemistry. 55(2). 783–796. 54 indexed citations
9.
Borthwick, Alan D., Steve P. Watson, Andrew R. Green, et al.. (2010). The characterization of a novel V1b antagonist lead series. Bioorganic & Medicinal Chemistry Letters. 21(1). 92–96. 2 indexed citations
10.
Borthwick, Alan D. & John Liddle. (2009). The design of orally bioavailable 2, 5‐diketopiperazine oxytocin antagonists: from concept to clinical candidate for premature labor. Medicinal Research Reviews. 31(4). 576–604. 31 indexed citations
11.
McCafferty, Gerald P., Mark Pullen, Charlene Wu, et al.. (2007). Use of a novel and highly selective oxytocin receptor antagonist to characterize uterine contractions in the rat. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 293(1). R299–R305. 22 indexed citations
12.
Wyatt, Paul G., Michael Allen, Alan D. Borthwick, et al.. (2005). 2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR. Bioorganic & Medicinal Chemistry Letters. 15(10). 2579–2582. 50 indexed citations
13.
Borthwick, Alan D.. (2005). Design of translactam HCMV protease inhibitors as potent antivirals. Medicinal Research Reviews. 25(4). 427–452. 21 indexed citations
14.
Borthwick, Alan D., et al.. (2002). Pyrrolidine-5,5-trans-lactams as novel mechanism-based inhibitors of human cytomegalovirus protease. Part 3: potency and plasma stability. Bioorganic & Medicinal Chemistry Letters. 12(13). 1719–1722. 20 indexed citations
15.
16.
Borthwick, Alan D., Terry Haley, Wei Wang, et al.. (1998). Design and synthesis of monocyclic β-lactams as mechanism-based inhibitors of human cytomegalovirus protease. Bioorganic & Medicinal Chemistry Letters. 8(4). 365–370. 140 indexed citations
17.
Kitchin, John R., et al.. (1995). Synthesis of Benzodioxinopyrroles as selective α2-adrenoceptor antagonists. Bioorganic & Medicinal Chemistry. 3(12). 1595–1603. 1 indexed citations
18.
Borthwick, Alan D., Barrie E. Kirk, Keith Biggadike, et al.. (1991). Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxyguanosines. Journal of Medicinal Chemistry. 34(3). 907–914. 44 indexed citations
19.
20.
Biggadike, Keith, Alan D. Borthwick, Anne M. Exall, et al.. (1987). Synthesis of fluorinated carbocyclic nucleosides: preparation of carbocyclic 1-(2′-deoxy-6′-fluororibofuranosyl)-5-iodouracils. Journal of the Chemical Society Chemical Communications. 255–256. 24 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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