Ayako Isotani

4.1k citations

48 papers · 2.7k indexed · 1 hit paper · h-index 23

Molecular Biology top 5%
Reproductive Medicine top 0.5%
Public Health, Environmental and Occupational Health top 1%
Genetics top 2%
Immunology top 10%

Co-authors: Masahito Ikawa Masaru Okabe Naokazu Inoue Yoshitaka Fujihara Yuhkoh Satouh Haruhiko Miyata Daisuke Mashiko Tomoko Nakanishi
Topics: CRISPR and Genetic Engineering (15 papers)Pluripotent Stem Cells Research (12 papers)Animal Genetics and Reproduction (12 papers)
Cited by: Reproductive Medicine Aging Public Health, Environmental and Occupational Health
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: Japan United States United Kingdom

In The Last Decade

Ayako Isotani

47 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

2005 596 citations Masahito Ikawa, Ayako Isotani et al. profile →

Peers

Countries citing papers authored by Ayako Isotani

Since Specialization

Citations

This map shows the geographic impact of Ayako Isotani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ayako Isotani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ayako Isotani more than expected).

Fields of papers citing papers by Ayako Isotani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ayako Isotani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ayako Isotani. The network helps show where Ayako Isotani may publish in the future.

Co-authorship network of co-authors of Ayako Isotani

This figure shows the co-authorship network connecting the top 25 collaborators of Ayako Isotani. A scholar is included among the top collaborators of Ayako Isotani based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ayako Isotani. Ayako Isotani is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Astrocyte-Specific Inhibition of the Primary Cilium Suppresses C3 Expression in Reactive Astrocyte 2024 ·Cellular and Molecular Neurobiology ·(unknown),(unknown),(unknown),(unknown),Michinori Toriyama,(unknown),(unknown),(unknown),Ayako Isotani,(unknown),Hiroshi Itoh	2
2	Acquisition of neural fate by combination of BMP blockade and chromatin modification 2023 ·iScience ·(unknown),(unknown),(unknown),Yoshihiro Takihara,(unknown),(unknown),Ayako Isotani,(unknown),Noriaki Sasai	3
3	Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung 2022 ·Cell Reports ·Takumi Kawasaki,(unknown),(unknown),(unknown),Daisuke Ori,Ken J. Ishii,Etsushi Kuroda,Shiki Takamura,Masahiro Kitabatake,Toshihiro Ito,Ayako Isotani,Taro Kawai	27
4	T Cell-Intrinsic Vitamin A Metabolism and Its Signaling Are Targets for Memory T Cell-Based Cancer Immunotherapy 2022 ·Frontiers in Immunology ·Fumihiro Fujiki,Soyoko Morimoto,(unknown),(unknown),(unknown),(unknown),(unknown),Ayako Isotani,Masahito Ikawa,Sumiyuki Nishida,Hiroko Nakajima,Akihiro Tsuboi,Yoshitaka Oka,Jun Nakata,Naoki Hosen,Atsushi Kumanogoh,Yusuke Oji,Haruo Sugiyama	8
5	Sperm IZUMO1 Is Required for Binding Preceding Fusion With Oolemma in Mice and Rats 2022 ·Frontiers in Cell and Developmental Biology ·Takafumi Matsumura,Taichi Noda,Yuhkoh Satouh,Akane Morohoshi,(unknown),Masaki Ogawa,Yonggang Lu,Ayako Isotani,Masahito Ikawa	15
6	Copine-7 is required for REM sleep regulation following cage change or water immersion and restraint stress in mice 2020 ·Neuroscience Research ·(unknown),C. Y. Tsai,(unknown),Nanae Nagata,(unknown),Ayako Isotani,Masashi Yanagisawa,Yu Hayashi	7
7	Male mice, caged in the International Space Station for 35 days, sire healthy offspring 2019 ·Scientific Reports ·Takafumi Matsumura,Taichi Noda,Masafumi Muratani,Risa Okada,(unknown),Ayako Isotani,Takashi Kudo,Satoru Takahashi,Masahito Ikawa	22
8	Knockdown of the mitochondria‐localized protein p13 protects against experimental parkinsonism 2018 ·EMBO Reports ·Naoki Inoue,(unknown),Atsushi Kasai,Takanobu Nakazawa,Kazuya Ikeda,(unknown),Ayako Isotani,Kousuke Baba,Hideki Mochizuki,Harutoshi Fujimura,Yukio Ago,Atsuko Hayata‐Takano,Kaoru Seiriki,Yusuke Shintani,Norihito Shintani,Hitoshi Hashimoto	19
9	CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice 2016 ·Scientific Reports ·Asami Oji,Taichi Noda,Yoshitaka Fujihara,Haruhiko Miyata,Yeon Joo Kim,Masanaga Muto,Kaori Nozawa,Takafumi Matsumura,Ayako Isotani,Masahito Ikawa	80
10	Generation of Hprt-disrupted rat through mouse←rat ES chimeras 2016 ·Scientific Reports ·Ayako Isotani,Kazuo Yamagata,Masaru Okabe,Masahito Ikawa	17
11	One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT) 2015 ·BMC Genomics ·Masato Ohtsuka,Hiromi Miura,Keiji Mochida,Michiko Hirose,Ayumi Hasegawa,Atsuo Ogura,Ryuta Mizutani,Minoru Kimura,Ayako Isotani,Masahito Ikawa,Masahiro Sato,Channabasavaiah B. Gurumurthy	18
12	Calreticulin is required for development of the cumulus oocyte complex and female fertility 2015 ·Scientific Reports ·Keizo Tokuhiro,Yuhkoh Satouh,Kaori Nozawa,Ayako Isotani,Yoshitaka Fujihara,(unknown),Hiroyuki Matsumura,Kazuhiro Takumi,Takashi Miyano,Masaru Okabe,Adam M. Benham,Masahito Ikawa	34
13	Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA 2013 ·Scientific Reports ·Daisuke Mashiko,Yoshitaka Fujihara,Yuhkoh Satouh,Haruhiko Miyata,Ayako Isotani,Masahito Ikawa	333
14	Formation of a thymus from rat ES cells in xenogeneic nude mouse↔rat ES chimeras 2011 ·Genes to Cells ·Ayako Isotani,(unknown),Kazuhiro Kaseda,Masahito Ikawa,Masaru Okabe	85
15	A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice 2009 ·Nature Genetics ·Chikara Kokubu,Kyoji Horie,Koichiro Abe,Ryuji Ikeda,(unknown),Yoshihiro Uno,Sanae Ogiwara,Masato Ohtsuka,Ayako Isotani,Masaru Okabe,Kenji Imai,Junji Takeda	48
16	Disruption of ADAM3 Impairs the Migration of Sperm into Oviduct in Mouse1 2009 ·Biology of Reproduction ·Ryo Yamaguchi,Yuko Muro,Ayako Isotani,Keizo Tokuhiro,Kazuhiro Takumi,Ibrahim M. Adham,Masahito Ikawa,Masaru Okabe	127
17	OAZ-t/OAZ3 Is Essential for Rigid Connection of Sperm Tails to Heads in Mouse 2009 ·PLoS Genetics ·Keizo Tokuhiro,Ayako Isotani,Sadaki Yokota,Yoshihisa Yano,Shigeru Oshio,Mika Hirose,Morimasa Wada,Kyoko Fujita,Yukiko Ogawa,Masaru Okabe,Yoshitake Nishimune,Hiromitsu Tanaka	84
18	Meichroacidin Containing the Membrane Occupation and Recognition Nexus Motif Is Essential for Spermatozoa Morphogenesis 2008 ·Journal of Biological Chemistry ·Keizo Tokuhiro,Mika Hirose,Yasushi Miyagawa,Akira Tsujimura,Shinji Irie,Ayako Isotani,Masaru Okabe,Yoshiro Toyama,Chizuru Ito,Kiyotaka Toshimori,Ken Takeda,Shigeru Oshio,Hitoshi Tainaka,Junji Tsuchida,Äkïhïko Okuyama,Yoshitake Nishimune,Hiromitsu Tanaka	21
19	Comparison of Gene Expression in Male and Female Mouse Blastocysts Revealed Imprinting of the X-Linked Gene, Rhox5/Pem, at Preimplantation Stages 2006 ·Current Biology ·Shin Kobayashi,Ayako Isotani,Nathan Mise,Masamichi Yamamoto,Yoshitaka Fujihara,Kazuhiro Kaseda,Tomoko Nakanishi,Masahito Ikawa,Hiroshi Hamada,Kuniya Abe,Masaru Okabe	121
20	Selective Passage Through the Uterotubal Junction of Sperm from a Mixed Population Produced by Chimeras of Calmegin-Knockout and Wild-Type Male Mice1 2004 ·Biology of Reproduction ·Tomoko Nakanishi,Ayako Isotani,Ryo Yamaguchi,Masahito Ikawa,Tadashi Baba,Susan S. Suárez,Masaru Okabe	54

About Ayako Isotani

Ayako Isotani is a scholar working on Aging, Reproductive Medicine and Genetics, having authored 48 papers that have together received 2.7k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (15 papers), Pluripotent Stem Cells Research (12 papers) and Animal Genetics and Reproduction (12 papers). The work is most often cited by research in Reproductive Medicine (1.1k citations), Aging (77 citations) and Public Health, Environmental and Occupational Health (1.0k citations). Ayako Isotani has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Masahito Ikawa, Masaru Okabe, Naokazu Inoue, Yoshitaka Fujihara, Yuhkoh Satouh, Haruhiko Miyata, Daisuke Mashiko, Tomoko Nakanishi, Yuko Muro and Kazuhiro Kaseda. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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