Angela M. Lam

3.5k total citations · 1 hit paper
61 papers, 2.7k citations indexed

About

Angela M. Lam is a scholar working on Epidemiology, Hepatology and Infectious Diseases. According to data from OpenAlex, Angela M. Lam has authored 61 papers receiving a total of 2.7k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Epidemiology, 42 papers in Hepatology and 24 papers in Infectious Diseases. Recurrent topics in Angela M. Lam's work include Hepatitis C virus research (42 papers), Hepatitis B Virus Studies (40 papers) and HIV/AIDS drug development and treatment (20 papers). Angela M. Lam is often cited by papers focused on Hepatitis C virus research (42 papers), Hepatitis B Virus Studies (40 papers) and HIV/AIDS drug development and treatment (20 papers). Angela M. Lam collaborates with scholars based in United States, Canada and Belgium. Angela M. Lam's co-authors include David N. Frick, Christine Espiritu, Phillip A. Furman, Michaël Otto, Shalini Bansal, Holly M. Micolochick Steuer, Michael J. Sofia, Congrong Niu, Meg Keilman and Pieter R. Cullis and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Angela M. Lam

60 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus

2010 486 citations Michael J. Sofia, Donghui Bao et al. profile →

Peers

Angela M. Lam

HEPAT

EPIDE

Congrong Niu United States

Nanhua Yao United States

Kai Lin United States

Christine Espiritu United States

Sophie Le Pogam United States

Klaus Klumpp United States

George Kukolj Canada

D R Averett United States

Brent E. Korba United States

Jin-Hua Sun United States

Congrong Niu United States

Angela M. Lam

1.1k ×0.7

HEPAT

1.2k ×0.9

EPIDE

842 ×0.8

674 ×0.7

179 ×0.7

Citations per year, relative to Angela M. Lam Angela M. Lam (= 1×) peers Congrong Niu

Countries citing papers authored by Angela M. Lam

Since Specialization

Citations

This map shows the geographic impact of Angela M. Lam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Angela M. Lam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Angela M. Lam more than expected).

Fields of papers citing papers by Angela M. Lam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Angela M. Lam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Angela M. Lam. The network helps show where Angela M. Lam may publish in the future.

Co-authorship network of co-authors of Angela M. Lam

This figure shows the co-authorship network connecting the top 25 collaborators of Angela M. Lam. A scholar is included among the top collaborators of Angela M. Lam based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Angela M. Lam. Angela M. Lam is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mesaros, Eugen F., Andrew G. Cole, Steven G. Kultgen, et al.. (2024). Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators. ACS Medicinal Chemistry Letters. 15(9). 1627–1634. 2 indexed citations

Lam, Angela M., Muhammad Sheraz, Fei Liu, et al.. (2024). Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161. Viruses. 16(3). 323–323. 5 indexed citations

Thi, Emily P., Xin Ye, Nicholas M. Snead, et al.. (2024). Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA Therapeutic. ACS Infectious Diseases. 10(10). 3640–3649. 6 indexed citations

Stoops, Bart, P.L. Shaffer, Angela M. Lam, et al.. (2023). Di-fluoro azepane HBV capsid assembly modulators. Bioorganic & Medicinal Chemistry Letters. 92. 129350–129350. 1 indexed citations

Kuduk, Scott D., Bart Stoops, Richard Alexander, et al.. (2021). Identification of a new class of HBV capsid assembly modulator. Bioorganic & Medicinal Chemistry Letters. 39. 127848–127848. 11 indexed citations

Kuduk, Scott D., Angela M. Lam, Christine Espiritu, et al.. (2019). SAR studies in the sulfonyl carboxamide class of HBV capsid assembly modulators. Bioorganic & Medicinal Chemistry Letters. 29(16). 2405–2409. 12 indexed citations

Klumpp, Klaus, Takashi Shimada, Lena Allweiss, et al.. (2017). Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection. Gastroenterology. 154(3). 652–662.e8. 78 indexed citations

Fyfe, Janet, Simon J. Foster, John H. Jardine, et al.. (2013). Detection and identification of mycobacteria in fixed stained smears and formalin‐fixed paraffin‐embedded tissues using PCR. Journal of Small Animal Practice. 54(12). 638–646. 14 indexed citations

Du, Jinfa, Donghui Bao, Ying Jiang, et al.. (2012). β-d-2′-α-F-2′-β-C-Methyl-6-O-substituted 3′,5′-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: A structure–activity relationship study. Bioorganic & Medicinal Chemistry Letters. 22(18). 5924–5929. 13 indexed citations

10.

Furman, Phillip A., Eisuke Murakami, Congrong Niu, et al.. (2011). Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661. Antiviral Research. 91(2). 120–132. 36 indexed citations

11.

Frick, David N., et al.. (2009). A Method to Simultaneously Monitor Hepatitis C Virus NS3 Helicase and Protease Activities. Methods in molecular biology. 587. 223–233. 14 indexed citations

12.

Heck, Julie A., et al.. (2008). Effects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various Genotypes. Antimicrobial Agents and Chemotherapy. 52(6). 1901–1911. 24 indexed citations

13.

Frick, David N. & Angela M. Lam. (2006). Understanding Helicases as a Means of Virus Control. Current Pharmaceutical Design. 12(11). 1315–1338. 91 indexed citations

14.

Lam, Angela M., et al.. (2005). Calcium enhances the transfection potency of stabilized plasmid–lipid particles. Analytical Biochemistry. 341(1). 156–164. 19 indexed citations

15.

Lam, Angela M.. (2004). Enhanced nucleic acid binding to ATP-bound hepatitis C virus NS3 helicase at low pH activates RNA unwinding. Nucleic Acids Research. 32(13). 4060–4070. 31 indexed citations

16.

Frick, David N., et al.. (2004). The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA Efficiently. Journal of Biological Chemistry. 279(2). 1269–1280. 92 indexed citations

17.

Lam, Angela M., David Keeney, & David N. Frick. (2003). Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action. Journal of Biological Chemistry. 278(45). 44514–44524. 56 indexed citations

18.

Palmer, Lorne, Tao Chen, Angela M. Lam, et al.. (2003). Transfection properties of stabilized plasmid–lipid particles containing cationic PEG lipids. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1611(1-2). 204–216. 39 indexed citations

19.

Lam, Angela M. & Pieter R. Cullis. (2000). Calcium enhances the transfection potency of plasmid DNA–cationic liposome complexes. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1463(2). 279–290. 61 indexed citations

20.

Lam, Angela M., et al.. (1999). Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1419(2). 137–150. 77 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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