Angela M. Lam

3.5k citations

61 papers · 2.7k indexed · 1 hit paper · h-index 27

Co-authors: David N. Frick Christine Espiritu Phillip A. Furman Michaël Otto Shalini Bansal Holly M. Micolochick Steuer Michael J. Sofia Congrong Niu
Topics: Hepatitis C virus research (42 papers)Hepatitis B Virus Studies (40 papers)HIV/AIDS drug development and treatment (20 papers)
Cited by: Hepatology Infectious Diseases Epidemiology
Journals: Nature Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: United States Canada Belgium

In The Last Decade

Angela M. Lam

60 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus

2010 486 citations Michael J. Sofia, Donghui Bao et al. profile →

Peers

Countries citing papers authored by Angela M. Lam

Since Specialization

Citations

This map shows the geographic impact of Angela M. Lam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Angela M. Lam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Angela M. Lam more than expected).

Fields of papers citing papers by Angela M. Lam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Angela M. Lam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Angela M. Lam. The network helps show where Angela M. Lam may publish in the future.

Co-authorship network of co-authors of Angela M. Lam

This figure shows the co-authorship network connecting the top 25 collaborators of Angela M. Lam. A scholar is included among the top collaborators of Angela M. Lam based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Angela M. Lam. Angela M. Lam is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators 2024 ·ACS Medicinal Chemistry Letters ·Eugen F. Mesaros,Andrew G. Cole,Steven G. Kultgen,Nagraj Mani,Kristi Fan,(unknown),(unknown),(unknown),Holly M. Micolochick Steuer,(unknown),(unknown),Troy O. Harasym,Angela M. Lam,Emily P. Thi,Bruce D. Dorsey,Michael J. Sofia	2
2	Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161 2024 ·Viruses ·Angela M. Lam,(unknown),Muhammad Sheraz,Fei Liu,Emily P. Thi,(unknown),Andrea Cuconati,Holly M. Micolochick Steuer,(unknown),(unknown),Jeremy D. Mason,(unknown),Andrew G. Cole,Troy O. Harasym,Michael J. Sofia	5
3	Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA Therapeutic 2024 ·ACS Infectious Diseases ·Emily P. Thi,Xin Ye,Nicholas M. Snead,Amy C. H. Lee,Holly M. Micolochick Steuer,(unknown),(unknown),Christine Espiritu,Andrea Cuconati,(unknown),(unknown),(unknown),Bhavna Paratala,Kevin McClintock,Troy O. Harasym,René Rijnbrand,Angela M. Lam,Michael J. Sofia	6
4	Di-fluoro azepane HBV capsid assembly modulators 2023 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Bart Stoops,P.L. Shaffer,Angela M. Lam,Christine Espiritu,Robert Vogel,(unknown),Osvaldo Flores,Scott D. Kuduk	1
5	Identification of a new class of HBV capsid assembly modulator 2021 ·Bioorganic & Medicinal Chemistry Letters ·Scott D. Kuduk,Bart Stoops,Richard Alexander,Angela M. Lam,Christine Espiritu,Robert Vogel,(unknown),Klaus Klumpp,Osvaldo Flores,George D. Hartman	11
6	SAR studies in the sulfonyl carboxamide class of HBV capsid assembly modulators 2019 ·Bioorganic & Medicinal Chemistry Letters ·Scott D. Kuduk,Angela M. Lam,Christine Espiritu,Robert Vogel,(unknown),Klaus Klumpp,Osvaldo Flores,George D. Hartman	12
7	Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection 2017 ·Gastroenterology ·Klaus Klumpp,Takashi Shimada,Lena Allweiss,Tassilo Volz,Marc Lütgehetmann,George D. Hartman,Osvaldo Flores,Angela M. Lam,Maura Dandri	78
8	Detection and identification of mycobacteria in fixed stained smears and formalin‐fixed paraffin‐embedded tissues using PCR 2013 ·Journal of Small Animal Practice ·(unknown),Janet Fyfe,Simon J. Foster,(unknown),(unknown),John H. Jardine,Angela M. Lam,C. O’Brien,Richard Malík	14
9	β-d-2′-α-F-2′-β-C-Methyl-6-O-substituted 3′,5′-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: A structure–activity relationship study 2012 ·Bioorganic & Medicinal Chemistry Letters ·Jinfa Du,Donghui Bao,(unknown),Ying Jiang,P. Ganapati Reddy,Hai‐Ren Zhang,Bruce S. Ross,Shalini Bansal,Haiying Bao,Christine Espiritu,Angela M. Lam,Eisuke Murakami,Congrong Niu,Holly M. Micolochick Steuer,Phillip A. Furman,Michaël Otto,Michael J. Sofia	13
10	Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661 2011 ·Antiviral Research ·Phillip A. Furman,Eisuke Murakami,Congrong Niu,Angela M. Lam,Christine Espiritu,Shalini Bansal,Haiying Bao,Tatiana Tolstykh,Holly M. Micolochick Steuer,Meg Keilman,Véronique Zennou,Nigel Bourne,Ronald L. Veselenak,Wonsuk Chang,Bruce S. Ross,Jinfa Du,Michaël Otto,Michael J. Sofia	36
11	A Method to Simultaneously Monitor Hepatitis C Virus NS3 Helicase and Protease Activities 2009 ·Methods in molecular biology ·David N. Frick,(unknown),Angela M. Lam	14
12	Effects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various Genotypes 2008 ·Antimicrobial Agents and Chemotherapy ·Julie A. Heck,Angela M. Lam,(unknown),David N. Frick	24
13	Understanding Helicases as a Means of Virus Control 2006 ·Current Pharmaceutical Design ·David N. Frick,Angela M. Lam	91
14	Calcium enhances the transfection potency of stabilized plasmid–lipid particles 2005 ·Analytical Biochemistry ·(unknown),Angela M. Lam,David B. Fenske,Lorne Palmer,Michael Johnston,Pieter R. Cullis	19
15	Enhanced nucleic acid binding to ATP-bound hepatitis C virus NS3 helicase at low pH activates RNA unwinding 2004 ·Nucleic Acids Research ·Angela M. Lam	31
16	The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA Efficiently 2004 ·Journal of Biological Chemistry ·David N. Frick,(unknown),Angela M. Lam,Baohua Gu	92
17	Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action 2003 ·Journal of Biological Chemistry ·Angela M. Lam,David Keeney,David N. Frick	56
18	Transfection properties of stabilized plasmid–lipid particles containing cationic PEG lipids 2003 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Lorne Palmer,Tao Chen,Angela M. Lam,David B. Fenske,Kim F. Wong,Ian MacLachlan,Pieter R. Cullis	39
19	Calcium enhances the transfection potency of plasmid DNA–cationic liposome complexes 2000 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Angela M. Lam,Pieter R. Cullis	61
20	Stabilized plasmid-lipid particles: factors influencing plasmid entrapment and transfection properties 1999 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·(unknown),Angela M. Lam,Pieter R. Cullis	77

About Angela M. Lam

Angela M. Lam is a scholar working on Hepatology, Infectious Diseases and Epidemiology, having authored 61 papers that have together received 2.7k indexed citations. Recurring topics across this work include Hepatitis C virus research (42 papers), Hepatitis B Virus Studies (40 papers) and HIV/AIDS drug development and treatment (20 papers). The work is most often cited by research in Hepatology (1.5k citations), Infectious Diseases (1.1k citations) and Epidemiology (1.4k citations). Angela M. Lam has collaborated with scholars based in United States, Canada and Belgium. Frequent co-authors include David N. Frick, Christine Espiritu, Phillip A. Furman, Michaël Otto, Shalini Bansal, Holly M. Micolochick Steuer, Michael J. Sofia, Congrong Niu, Meg Keilman and Pieter R. Cullis. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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