Takashi Shimada

22.5k total citations · 5 hit papers
318 papers, 17.3k citations indexed

About

Takashi Shimada is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Takashi Shimada has authored 318 papers receiving a total of 17.3k indexed citations (citations by other indexed papers that have themselves been cited), including 154 papers in Molecular Biology, 82 papers in Genetics and 45 papers in Oncology. Recurrent topics in Takashi Shimada's work include Virus-based gene therapy research (61 papers), RNA Interference and Gene Delivery (29 papers) and Alkaline Phosphatase Research Studies (23 papers). Takashi Shimada is often cited by papers focused on Virus-based gene therapy research (61 papers), RNA Interference and Gene Delivery (29 papers) and Alkaline Phosphatase Research Studies (23 papers). Takashi Shimada collaborates with scholars based in Japan, United States and United Kingdom. Takashi Shimada's co-authors include Seiji Fukumoto, Toshiro Fujita, Takeyoshi Yamashita, Hisashi Hasegawa, Y. Yamazaki, Yasuhiro Takeuchi, Itaru Urakawa, Takanori Muto, Makoto Kakitani and Kazuma Tomizuka and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Takashi Shimada

314 papers receiving 16.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Klotho converts canonical FGF receptor into a specific receptor for FGF23

2006 1.4k citations Itaru Urakawa, Takashi Shimada et al. profile →
FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

2004 1.4k citations Takashi Shimada, Hisashi Hasegawa et al. Journal of Bone and Mineral Research profile →
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

2004 1.1k citations Takashi Shimada, Makoto Kakitani et al. profile →
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

2001 1.1k citations Takashi Shimada, S. Mizutani et al. Proceedings of the National Academy of Sciences profile →
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

2004 1.0k citations Takashi Shimada, Makoto Kakitani et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Takashi Shimada Japan	57	6.9k	6.9k	5.7k	2.6k	2.1k	318	17.3k
Dwight A. Towler United States	58	5.7k 0.8×	1.9k 0.3×	2.0k 0.3×	530 0.2×	1.1k 0.5×	105	10.9k
Cees van Kooten Netherlands	69	3.5k 0.5×	2.7k 0.4×	841 0.1×	1.1k 0.4×	2.1k 1.0×	365	19.6k
Michael Kashgarian United States	63	5.1k 0.7×	2.6k 0.4×	750 0.1×	700 0.3×	884 0.4×	265	13.5k
Karl V. Voelkerding United States	32	11.2k 1.6×	529 0.1×	9.8k 1.7×	1.9k 0.7×	1.6k 0.7×	86	23.1k
David P. Witte United States	65	5.9k 0.9×	802 0.1×	1.6k 0.3×	752 0.3×	1.9k 0.9×	240	13.3k
Roland Baron United States	80	14.8k 2.2×	927 0.1×	2.9k 0.5×	1.6k 0.6×	7.5k 3.5×	252	22.7k
Hidehiko Saito Japan	67	6.9k 1.0×	384 0.1×	1.3k 0.2×	1.7k 0.7×	2.3k 1.1×	484	18.5k
Rikard Holmdahl Sweden	89	6.3k 0.9×	401 0.1×	2.1k 0.4×	1.4k 0.5×	4.1k 1.9×	636	27.5k
Liliana Schaefer Germany	64	6.5k 0.9×	1.0k 0.1×	1.1k 0.2×	617 0.2×	1.3k 0.6×	193	14.0k
Thomas Doetschman United States	63	13.8k 2.0×	531 0.1×	3.3k 0.6×	648 0.2×	1.9k 0.9×	134	19.5k

Countries citing papers authored by Takashi Shimada

Since Specialization

Citations

This map shows the geographic impact of Takashi Shimada's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Takashi Shimada with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Takashi Shimada more than expected).

Fields of papers citing papers by Takashi Shimada

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Takashi Shimada. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Takashi Shimada. The network helps show where Takashi Shimada may publish in the future.

Co-authorship network of co-authors of Takashi Shimada

This figure shows the co-authorship network connecting the top 25 collaborators of Takashi Shimada. A scholar is included among the top collaborators of Takashi Shimada based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Takashi Shimada. Takashi Shimada is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Minegishi, Yuriko, Noriko Iwamoto, Takashi Shimada, et al.. (2023). 149 Simultaneous identification of KRAS mutation-carrying multiple neoepitopes by differential ion mobility-assisted targeted-mass spectrometry. SHILAP Revista de lepidopterología. A169–A169. 1 indexed citations

Iwamoto, Noriko, Yoshinobu Koguchi, Akinobu Hamada, et al.. (2022). A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics. The Analyst. 147(19). 4275–4284. 4 indexed citations

Yamaguchi, Teruhide, Eriko Uchida, Takashi Okada, et al.. (2020). Aspects of Gene Therapy Products Using Current Genome-Editing Technology in Japan. Human Gene Therapy. 31(19-20). 1043–1053. 10 indexed citations

Uemura, Takeshi, Tomoko Shiroshima, Asami Maeda, et al.. (2017). In situ screening for postsynaptic cell adhesion molecules during synapse formation. The Journal of Biochemistry. 162(4). 295–302. 3 indexed citations

Hara, Keisuke, Atsushi Watanabe, Satoshi Matsumoto, et al.. (2015). Surgical Specimens of Colorectal Cancer Fixed with PAXgene Tissue System Preserve High-Quality RNA. Biopreservation and Biobanking. 13(5). 325–334. 8 indexed citations

Watanabe, Thomas K., et al.. (2012). Perinatal (Lethal) Type Of Hypophosphatasia Resulting From Paternal Isodisomy Of Chromosome 1. 51(1). 23. 1 indexed citations

Kato, Shigeki, Kenta Kobayashi, Ken‐ichi Inoue, et al.. (2010). A Lentiviral Strategy for Highly Efficient Retrograde Gene Transfer by Pseudotyping with Fusion Envelope Glycoprotein. Human Gene Therapy. 22(2). 197–206. 113 indexed citations

Watanabe, Atsushi, Tatsuki Karasugi, Hideaki Sawai, et al.. (2010). Prevalence of c.1559delT in ALPL, a common mutation resulting in the perinatal (lethal) form of hypophosphatasia in Japanese and effects of the mutation on heterozygous carriers. Journal of Human Genetics. 56(2). 166–168. 56 indexed citations

Utoh, Rie, Chise Tateno, Miho Kataoka, et al.. (2010). Hepatic Hyperplasia Associated with Discordant Xenogeneic Parenchymal-Nonparenchymal Interactions in Human Hepatocyte-Repopulated Mice. American Journal Of Pathology. 177(2). 654–665. 23 indexed citations

10.

Yamazaki, Y., Taro Tamada, Noriyuki Kasai, et al.. (2008). Anti-FGF23 Neutralizing Antibodies Show the Physiological Role and Structural Features of FGF23. Journal of Bone and Mineral Research. 23(9). 1509–1518. 155 indexed citations

11.

Tateno, Chise, Asato Tachibana, Rie Utoh, et al.. (2007). GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver. Journal of Endocrinology. 194(3). 529–537. 27 indexed citations

12.

Shimada, Takashi, Y. Yamazaki, M Takahashi, et al.. (2005). Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism. American Journal of Physiology-Renal Physiology. 289(5). F1088–F1095. 273 indexed citations

13.

Shimada, Takashi, Hisashi Hasegawa, Y. Yamazaki, et al.. (2004). FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis. Journal of Bone and Mineral Research. 19(3). 429–435. 1421 indexed citations breakdown →

14.

Shimada, Takashi, S. Mizutani, Takanori Muto, et al.. (2001). Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proceedings of the National Academy of Sciences. 98(11). 6500–6505. 1087 indexed citations breakdown →

15.

Migita, Makoto, et al.. (2001). DIFFERENTIATION OF TRANSPLANTED BONE MARROW CELLS IN THE ADULT MOUSE BRAIN1. Transplantation. 71(12). 1735–1740. 101 indexed citations

16.

Orimo, Hideo, Eiitsu Nakajima, M. Yamamoto, et al.. (2000). Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability. Journal of Human Genetics. 45(4). 228–230. 18 indexed citations

17.

Orimo, Hideo, Eiitsu Nakajima, Miyoko Ikejima, Mitsuru Emi, & Takashi Shimada. (1999). Frameshift Mutations and a Length Polymorphism in the hMSH3 Gene and the Spectrum of Microsatellite Instability in Sporadic Colon Cancer. Japanese Journal of Cancer Research. 90(12). 1310–1315. 6 indexed citations

18.

Gemma, Akihiko, Yuichiro Takeda, K. Takenaka, et al.. (1996). Stability of p53 tumor suppressor gene mutations during the process of metastasis and during chemotherapy. Lung Cancer. 14(2-3). 219–228. 7 indexed citations

19.

Palombo, Fabio, Ingram Iaccarino, Eiitsu Nakajima, et al.. (1996). hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA. Current Biology. 6(9). 1181–1184. 304 indexed citations

20.

Shimada, Takashi, Koiti Inokuchi, & Arthur W. Nienhuis. (1987). Site-Specific Demethylation and Normal Chromatin Structure of the Human Dihydrofolate Reductase Gene Promoter after Transfection into CHO Cells. Molecular and Cellular Biology. 7(8). 2830–2837. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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