Alessandro Moretta

55.1k total citations · 13 hit papers
376 papers, 43.6k citations indexed

About

Alessandro Moretta is a scholar working on Immunology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Alessandro Moretta has authored 376 papers receiving a total of 43.6k indexed citations (citations by other indexed papers that have themselves been cited), including 367 papers in Immunology, 83 papers in Oncology and 41 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Alessandro Moretta's work include Immune Cell Function and Interaction (336 papers), T-cell and B-cell Immunology (299 papers) and CAR-T cell therapy research (67 papers). Alessandro Moretta is often cited by papers focused on Immune Cell Function and Interaction (336 papers), T-cell and B-cell Immunology (299 papers) and CAR-T cell therapy research (67 papers). Alessandro Moretta collaborates with scholars based in Italy, France and United States. Alessandro Moretta's co-authors include Lorenzo Moretta, Cristina Bottino, Maria Cristina Mingari, Roberto Biassoni, Daniela Pende, Massimo Vitale, Emanuela Marcenaro, Simona Sivori, Claudia Cantoni and Roberta Castriconi and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Alessandro Moretta

374 papers receiving 42.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Innate or Adaptive Immunity? The Example of Natural Killer Cells

2011 2.0k citations Éric Vivier, Alessandro Moretta et al. profile →
Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis

2001 1.4k citations Alessandro Moretta, Cristina Bottino et al. profile →
RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

1996 749 citations Alessandro Moretta, Cristina Bottino et al. profile →
Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule

2003 705 citations Cristina Bottino, Roberta Castriconi et al. The Journal of Experimental Medicine profile →
Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor

1997 639 citations Massimo Vitale, Alessandro Moretta et al. profile →
Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells

1999 611 citations Daniela Pende, Silvia Parolini et al. The Journal of Experimental Medicine profile →
NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis

1998 590 citations Massimo Vitale, Cristina Bottino et al. The Journal of Experimental Medicine profile →
Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells

2003 574 citations Roberta Castriconi, Claudia Cantoni et al. Proceedings of the National Academy of Sciences profile →
Natural killer cells and dendritic cells: rendezvous in abused tissues

2002 552 citations Alessandro Moretta profile →
The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

2009 526 citations Cameron S. Brandt, Myriam Baratin et al. The Journal of Experimental Medicine profile →
Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

2011 513 citations François Romagné, Alessandro Moretta et al. profile →
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

1995 500 citations Roberto Biassoni, Claudia Cantoni et al. profile →
Subpopulations of Human T Cells Identified by Receptors for Immunoglobulins and Mitogen Responsiveness

1976 374 citations Lorenzo Moretta, Maria Cristina Mingari et al. The Journal of Immunology profile →

Peers

Countries citing papers authored by Alessandro Moretta

Since Specialization

Citations

This map shows the geographic impact of Alessandro Moretta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alessandro Moretta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alessandro Moretta more than expected).

Fields of papers citing papers by Alessandro Moretta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alessandro Moretta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alessandro Moretta. The network helps show where Alessandro Moretta may publish in the future.

Co-authorship network of co-authors of Alessandro Moretta

This figure shows the co-authorship network connecting the top 25 collaborators of Alessandro Moretta. A scholar is included among the top collaborators of Alessandro Moretta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alessandro Moretta. Alessandro Moretta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content 2018 ·The Journal of Immunology ·Marı́a Rosa Bono, Daniela Pende, Alice Bertaina, Alessandro Moretta, Mariella Della Chiesa, Simona Sivori, Marco Zecca, Franco Locatelli, Lorenzo Moretta, Cristina Bottino, Michela Falco	5
2	Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients 2017 ·European Journal of Immunology ·Raffaella Meazza, Michela Falco, Stefania Marcenaro, Fabrizio Loiacono, Paolo Canevali, Francesca Bellora, (unknown), Franco Locatelli, Concetta Micalizzi, Alessandro Moretta, Maria Cristina Mingari, Lorenzo Moretta, Maurizio Aricò, Cristina Bottino, Daniela Pende	16
3	Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity 2016 ·Cancer Research ·Christine L. Pasero, Gwénaëlle Gravis, Mathilde Guérin, Samuel Granjeaud, Jeanne Thomassin‐Piana, Palma Rocchi, (unknown), Flora Poizat, (unknown), (unknown), Jochen Walz, Naji Salem, Serge Brunelle, Alessandro Moretta, Daniel Olive	156
4	Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis 2014 ·Journal of Allergy and Clinical Immunology ·Raffaella Meazza, (unknown), Valentina Cetica, Michela Falco, Silvia Parolini, (unknown), Gillian M. Griffiths, Elena Sieni, Stefania Marcenaro, Concetta Micalizzi, Davide Montin, Franca Fagioli, Alessandro Moretta, Maria Cristina Mingari, Lorenzo Moretta, Luigi D. Notarangelo, Cristina Bottino, Maurizio Aricò, Daniela Pende	17
5	A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2 2010 ·Blood ·Simona Sivori, Michela Falco, Simona Carlomagno, Elisa Romeo, Cristiana Soldani, Armand Bensussan, Antonella Viola, Lorenzo Moretta, Alessandro Moretta	73
6	The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans breakdown → 2009 ·The Journal of Experimental Medicine ·Cameron S. Brandt, Myriam Baratin, Eugene C. Yi, Jacob J. Kennedy, Zeren Gao, Brian A. Fox, Betty Haldeman, (unknown), Tomonori Kaifu, Christian Chabannon, Alessandro Moretta, Robert West, Wenfeng Xu, Éric Vivier, Steven D. Levin	526
7	NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties 2009 ·The Journal of Immunology ·Roberta Castriconi, Antonio Daga, Alessandra Dondero, Gianluigi Zona, Pietro Luigi Poliani, Alice Melotti, (unknown), Daniela Marubbi, Renato Spaziante, Francesca Bellora, Lorenzo Moretta, Alessandro Moretta, Giorgio Corte, Cristina Bottino	274
8	Heterogeneity of TLR3 mRNA transcripts and responsiveness to poly (I:C) in human NK cells derived from different donors 2007 ·International Immunology ·Simona Sivori, Michela Falco, Simona Carlomagno, Elisa Romeo, Lorenzo Moretta, Alessandro Moretta	25
9	Phenotypic Studies of Natural Killer Cell Subsets in Human Transporter Associated with Antigen Processing Deficiency 2007 ·PLoS ONE ·Jacques Zimmer, Huguette Bausinger, Emmanuel Andrès, Lionel Donato, Daniel Hanau, François Hentges, Alessandro Moretta, Henri de la Salle	7
10	NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection 2007 ·The Journal of Immunology ·Monia Draghi, Achal Pashine, Bharati M. Sanjanwala, Ketevan Gendzekhadze, Claudia Cantoni, David Cosman, Alessandro Moretta, Nicholas M. Valiante, Peter Parham	159
11	NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Receptors 2005 ·The Journal of Immunology ·Béatrice Le Maux Chansac, Alessandro Moretta, Isabelle Vergnon, Paule Opolon, Yann Lécluse, Dominique Grunenwald, Marek Kubin, Jean‐Charles Soria, Salem Chouaı̈b, Fathia Mami‐Chouaib	65
12	Molecular and Functional Characterization of NKG2D, NKp80, and NKG2C Triggering NK Cell Receptors in Rhesus and Cynomolgus Macaques: Monitoring of NK Cell Function during Simian HIV Infection 2005 ·The Journal of Immunology ·Roberto Biassoni, Manuela Fogli, Claudia Cantoni, Paola Costa, Romana Conte, Gerrit Koopman, Aurelio Cafaro, Barbara Ensoli, Alessandro Moretta, Lorenzo Moretta, Andrea De Maria	36
13	The Inhibitory Receptor IRp60 (CD300a) Is Expressed and Functional on Human Mast Cells 2005 ·The Journal of Immunology ·Ido Bachelet, Ariel Munitz, Alessandro Moretta, Lorenzo Moretta, Francesca Levi‐Schaffer	129
14	CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells 2004 ·Proceedings of the National Academy of Sciences ·Simona Sivori, Michela Falco, Mariella Della Chiesa, Simona Carlomagno, Massimo Vitale, Lorenzo Moretta, Alessandro Moretta	368
15	Significant NK cell activation associated with decreased cytolytic function in peripheral blood of HIV‐1‐infected patients 2004 ·European Journal of Immunology ·Manuela Fogli, Paola Costa, Giuseppe Murdaca, Maurizio Setti, Maria Cristina Mingari, Lorenzo Moretta, Alessandro Moretta, Andrea De Maria	105
16	The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic 2004 ·The Journal of Immunology ·Guido Ferlazzo, Dolca Thomas, (unknown), (unknown), Barbara Morandi, William A. Müller, Alessandro Moretta, Christian Münz	451
17	Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements 2001 ·The Journal of Immunology ·Frédéric Vely, Marie‐Alix Peyrat, (unknown), Jean‐François Morcet, Franck Halary, François Davodeau, François Romagné, Emmanuel Scotet, Xavier Saulquin, Elisabeth Houssaint, N. Schleinitz, Alessandro Moretta, Éric Vivier, Marc Bonneville	72
18	Inhibitory and Activatory Receptors for HLA Class I Molecules in Human Natural Killer Cells 1996 ·Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy ·Alessandro Moretta, Massimo Vitale, Simona Sivori, Luigia Morelli, Daniela Pende, Cristina Bottino	8
19	Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain. 1988 ·The Journal of Experimental Medicine ·Alessandro Moretta, Cristina Bottino, Ermanno Ciccone, Giuseppe Tambussi, Maria Cristina Mingari, Silvano Ferrini, Giulia Casorati, Paola Varese, O Viale, Nicola Migone	31
20	Recent advances in the phenotypic and functional analysis of human T lymphocytes. 1984 ·PubMed ·Alessandro Moretta, Giuseppe Pantaleo, Enrico Maggi, Maria Cristina Mingari	13

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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