Cristina Bottino

25.5k total citations · 7 hit papers
186 papers, 20.9k citations indexed

About

Cristina Bottino is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Cristina Bottino has authored 186 papers receiving a total of 20.9k indexed citations (citations by other indexed papers that have themselves been cited), including 171 papers in Immunology, 47 papers in Oncology and 20 papers in Molecular Biology. Recurrent topics in Cristina Bottino's work include Immune Cell Function and Interaction (154 papers), T-cell and B-cell Immunology (118 papers) and CAR-T cell therapy research (31 papers). Cristina Bottino is often cited by papers focused on Immune Cell Function and Interaction (154 papers), T-cell and B-cell Immunology (118 papers) and CAR-T cell therapy research (31 papers). Cristina Bottino collaborates with scholars based in Italy, United States and France. Cristina Bottino's co-authors include Lorenzo Moretta, Alessandro Moretta, Roberto Biassoni, Massimo Vitale, Daniela Pende, Maria Cristina Mingari, Claudia Cantoni, Roberta Castriconi, Simona Sivori and Raffaella Augugliaro and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine and SHILAP Revista de lepidopterología.

In The Last Decade

Cristina Bottino

186 papers receiving 20.5k citations

Hit Papers

Activating Receptors and Coreceptors Involved in Human Na... 1995 2026 2005 2015 2001 1996 2003 1999 1998 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis
    2001 1.4k citations Alessandro Moretta, Cristina Bottino et al. profile →
  2. RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS
    1996 749 citations Alessandro Moretta, Cristina Bottino et al. profile →
  3. Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule
    2003 705 citations Cristina Bottino, Roberta Castriconi et al. The Journal of Experimental Medicine profile →
  4. Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells
    1999 611 citations Daniela Pende, Silvia Parolini et al. The Journal of Experimental Medicine profile →
  5. NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis
    1998 590 citations Massimo Vitale, Cristina Bottino et al. The Journal of Experimental Medicine profile →
  6. Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells
    2003 574 citations Roberta Castriconi, Claudia Cantoni et al. profile →
  7. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains
    1995 500 citations Roberto Biassoni, Claudia Cantoni et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Cristina Bottino Italy 74 19.1k 5.3k 2.1k 1.7k 1.3k 186 20.9k
Daniela Pende Italy 69 15.7k 0.8× 4.6k 0.9× 3.6k 1.7× 1.3k 0.7× 1.2k 0.9× 179 17.3k
Todd A. Fehniger United States 49 11.6k 0.6× 4.2k 0.8× 2.0k 0.9× 1.6k 0.9× 1.3k 1.0× 189 14.1k
Joseph H. Phillips United States 90 22.6k 1.2× 4.9k 0.9× 2.1k 1.0× 3.0k 1.7× 2.1k 1.6× 145 26.1k
Derek N.J. Hart Australia 55 10.2k 0.5× 2.6k 0.5× 1.3k 0.6× 2.7k 1.5× 1.1k 0.8× 237 13.0k
Roberto Biassoni Italy 55 13.2k 0.7× 3.1k 0.6× 1.5k 0.7× 1.3k 0.8× 992 0.8× 168 14.4k
Stephen L. Nutt Australia 84 15.0k 0.8× 3.9k 0.7× 2.2k 1.1× 6.6k 3.8× 1.2k 0.9× 242 22.1k
Maria Cristina Mingari Italy 77 17.8k 0.9× 5.7k 1.1× 2.2k 1.0× 2.6k 1.5× 1.4k 1.1× 256 22.1k
Massimo Vitale Italy 54 13.4k 0.7× 4.1k 0.8× 1.4k 0.6× 1.5k 0.8× 916 0.7× 108 14.8k
James L. Riley United States 67 12.3k 0.6× 9.7k 1.8× 788 0.4× 4.1k 2.3× 1.4k 1.1× 149 18.8k
Klas Kärre Sweden 56 12.9k 0.7× 3.3k 0.6× 1.1k 0.5× 1.8k 1.1× 1.4k 1.1× 180 14.7k

Countries citing papers authored by Cristina Bottino

Since Specialization
Citations

This map shows the geographic impact of Cristina Bottino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cristina Bottino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cristina Bottino more than expected).

Fields of papers citing papers by Cristina Bottino

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cristina Bottino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cristina Bottino. The network helps show where Cristina Bottino may publish in the future.

Co-authorship network of co-authors of Cristina Bottino

This figure shows the co-authorship network connecting the top 25 collaborators of Cristina Bottino. A scholar is included among the top collaborators of Cristina Bottino based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Cristina Bottino. Cristina Bottino is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Carlomagno, Simona, Michela Falco, Claudia Cantoni, et al.. (2025). CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors. Frontiers in Immunology. 16. 1481745–1481745. 2 indexed citations
2.
Bottino, Cristina, Chiara Vitale, Alessandra Dondero, & Roberta Castriconi. (2023). B7-H3 in Pediatric Tumors: Far beyond Neuroblastoma. Cancers. 15(13). 3279–3279. 17 indexed citations
3.
Falco, Michela, Raffaella Meazza, Claudia Alicata, et al.. (2022). Epitope characterization of a monoclonal antibody that selectively recognizes KIR2DL1 allotypes. HLA. 100(2). 107–118. 3 indexed citations
4.
Cangelosi, Davide, Martina Morini, Luca Mastracci, et al.. (2020). Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a. Disease Models & Mechanisms. 13(9). 11 indexed citations
5.
Bono, Marı́a Rosa, Daniela Pende, Alice Bertaina, et al.. (2018). Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content. The Journal of Immunology. 201(5). 1460–1467. 5 indexed citations
6.
Pende, Daniela, Raffaella Meazza, Stefania Marcenaro, Maurizio Aricò, & Cristina Bottino. (2018). 2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection. Clinical Immunology. 204. 31–36. 15 indexed citations
7.
Meazza, Raffaella, Michela Falco, Stefania Marcenaro, et al.. (2017). Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients. European Journal of Immunology. 47(6). 1051–1061. 16 indexed citations
8.
Cantoni, Claudia, Leticía Huergo-Zapico, Monica Parodi, et al.. (2016). NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?. Journal of Immunology Research. 2016. 1–13. 70 indexed citations
9.
Meazza, Raffaella, Valentina Cetica, Michela Falco, et al.. (2014). Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis. Journal of Allergy and Clinical Immunology. 134(6). 1381–1387.e7. 17 indexed citations
10.
Daga, Antonio, Cristina Bottino, Roberta Castriconi, Rosaria Gangemi, & Silvano Ferrini. (2011). New Perspectives in Glioma Immunotherapy. Current Pharmaceutical Design. 17(23). 2439–2467. 21 indexed citations
11.
Castriconi, Roberta, Antonio Daga, Alessandra Dondero, et al.. (2009). NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties. The Journal of Immunology. 182(6). 3530–3539. 274 indexed citations
12.
Gregorio, Andrea, Maria Valeria Corrias, Roberta Castriconi, et al.. (2008). Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7‐H3 surface molecule. Histopathology. 53(1). 73–80. 82 indexed citations
13.
Bottino, Cristina. (2004). Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells. Molecular Immunology. 41(6-7). 569–575. 53 indexed citations
14.
Castriconi, Roberta, Claudia Cantoni, Mariella Della Chiesa, et al.. (2003). TGFβ1 inhibits the surface expression of the NKp30 and NKG2D triggering NK receptors: consequences for the NK-mediated killing of dendritic cells. Italian Journal of Anatomy and Embryology. 42–42. 1 indexed citations
15.
Parolini, Silvia, Cristina Bottino, Michela Falco, et al.. (2000). X-Linked Lymphoproliferative Disease. The Journal of Experimental Medicine. 192(3). 337–346. 398 indexed citations
16.
Bottino, Cristina, Raffaella Augugliaro, Roberta Castriconi, et al.. (2000). Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells. European Journal of Immunology. 30(12). 3718–3722. 73 indexed citations
17.
18.
Biassoni, Roberto, Claudia Cantoni, Michela Falco, et al.. (1996). The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.. The Journal of Experimental Medicine. 183(2). 645–650. 305 indexed citations
19.
Moretta, Alessandro, Cristina Bottino, Ermanno Ciccone, et al.. (1988). Human peripheral blood lymphocytes bearing T cell receptor gamma/delta. Expression of CD8 differentiation antigen correlates with the expression of the 55-kD, C gamma 2-encoded gamma chain.. The Journal of Experimental Medicine. 168(6). 2349–2354. 31 indexed citations
20.
Moretta, Lorenzo, Daniela Pende, Cristina Bottino, et al.. (1987). Human CD3+4−8−WT31−T lymphocyte expressing the putative T cell receptor γ‐gene product. A limiting dilution and clonal analysis. European Journal of Immunology. 17(9). 1229–1234. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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