Alan S. Perelson

71.3k citations

521 papers · 46.5k indexed · 16 hit papers · h-index 104

Impact in

Virology top 0.01%
- HIV Research and Treatment
Modeling and Simulation top 0.02%

Papers in

Virology 194
- HIV Research and Treatment 194
Hepatology 119
- Hepatitis C virus research 118

Co-authors: David D. Ho Martin Markowitz Avidan U. Neumann Ruy M. Ribeiro John M. Leonard Rob J. de Boer Patrick W. Nelson Harel Dahari
Journals: Journal of Virology (40 papers)Journal of Theoretical Biology (40 papers)PLoS Computational Biology (31 papers)Proceedings of the National Academy of Sciences (31 papers)Mathematical Biosciences (17 papers)
Partner nations: United States Netherlands United Kingdom

In The Last Decade

Alan S. Perelson

515 papers receiving 44.8k citations

Hit Papers

15 papers align trajectories log scale

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues 2014 · 503 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2014 Proceedings of the National Academy of Sciences
2011 SIAM Review
2006 Journal of Virology
2002 Self-nonself discrimination in a computer
2002 Nature reviews. Immunology
1999 New England Journal of Medicine
1999 SIAM Review
1999 New England Journal of Medicine
1999 The Journal of Experimental Medicine
1998 Science
1997 Nature
1996 Science
1995 Nature
1993 Mathematical Biosciences
1986 Physica D Nonlinear Phenomena
1979 Journal of Theoretical Biology

Peers

Countries citing papers authored by Alan S. Perelson

Since Specialization

Citations

This map shows the geographic impact of Alan S. Perelson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alan S. Perelson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alan S. Perelson more than expected).

Fields of papers citing papers by Alan S. Perelson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alan S. Perelson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alan S. Perelson. The network helps show where Alan S. Perelson may publish in the future.

Co-authors

The 25 scholars most cited alongside Alan S. Perelson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alan S. Perelson Line = papers co-authored together Alan S. Perelson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy Proceedings of the National Academy of Sciences ·Jennifer A. White, Francesco R. Simonetti, Subul Beg, Natalie F. McMyn, Weiwei Dai, Niklas Bachmann, Jun Lai, William C. Ford, Christina Bunch, Joyce Jones, Ruy M. Ribeiro, Alan S. Perelson, Janet D. Siliciano, Robert F. Siliciano	2022	52
2	Antithetic effect of interferon-α on cell-free and cell-to-cell HIV-1 infection PLoS Computational Biology ·Ryuichi Kumata, Shoya Iwanami, Katrina B. Mar, Yusuke Kakizoe, Naoko Misawa, Shinji Nakaoka, Yoshio Koyanagi, Alan S. Perelson, John W. Schoggins, Shingo Iwami, Kei Sato	2022	2
3	Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action PLoS Computational Biology ·Peter Czuppon, Florence Débarre, António Gonçalves, Olivier Tenaillon, Alan S. Perelson, Jérémie Guedj, François Blanquart	2021	33
4	Suppression of hepatitis B virus through therapeutic activation of RIG-I and IRF3 signaling in hepatocytes iScience ·Sooyoung Lee, Ashish Goyal, Alan S. Perelson, Yuji Ishida, Takeshi Saito, Michael Gale	2021	24
5	A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies The Journal of Experimental Medicine ·Chase D. McCann, Christiaan H. van Dorp, Ali Danesh, Adam R. Ward, Thomas R. Dilling, Talia M. Mota, Elizabeth Zale, Eva M. Stevenson, Shabnum Patel, Chanson J. Brumme, Winnie Dong, D. S. Jones, Thomas L. Andresen, Bruce D. Walker, Zabrina L. Brumme, Catherine M. Bollard, Alan S. Perelson, Darrell J. Irvine, R. Brad Jones	2021	10
6	CD8 Lymphocyte Depletion Enhances the Latency Reversal Activity of the SMAC Mimetic AZD5582 in ART-Suppressed Simian Immunodeficiency Virus-Infected Rhesus Macaques Journal of Virology ·Maud Mavigner, Laura E. Liao, Alyssa D. Brooks, Ruian Ke, Cameron Mattingly, Nils Schoof, Julia Bergild McBrien, Diane G. Carnathan, Shan Liang, Thomas H. Vanderford, Mirko Paiardini, Deanna A. Kulpa, Jeffrey D. Lifson, Richard M. Dunham, Kirk A. Easley, David M. Margolis, Alan S. Perelson, Guido Silvestri, Ann Chahroudi	2021	20
7	Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size Clinical Infectious Diseases ·Sherazaan D. Ismail, Catherine Riou, Sarah Joseph, Nancie M. Archin, David M. Margolis, Alan S. Perelson, Tyler Cassidy, Melissa-Rose Abrahams, Matthew Moeser, Lyle R. McKinnon, Farzana Osman, Quarraisha Abdool Karim, Salim S. Abdool Karim, Ronald Swanstrom, Carolyn Williamson, Nigel Garrett, Wendy A. Burgers	2021	8
8	A direct-acting antiviral drug abrogates viremia in Zika virus–infected rhesus macaques Science Translational Medicine ·So‐Yon Lim, Christa E. Osuna, Katharine Best, Ray Taylor, Elsa Chen, Gyeol Yoon, Jessica Kublin, Dane Schalk, Nancy Schultz‐Darken, Saverio Capuano, David Safronetz, Ma Luo, Steve MacLennan, Amanda Mathis, Y.S. Babu, William Sheridan, Alan S. Perelson, James B. Whitney	2020	20
9	Regulation of T cell expansion by antigen presentation dynamics Proceedings of the National Academy of Sciences ·Andreas Mayer, Yaojun Zhang, Alan S. Perelson, Ned S. Wingreen	2019	60
10	Mathematical modelling identifies the role of adaptive immunity as a key controller of respiratory syncytial virus in cotton rats Journal of The Royal Society Interface ·Darren Wethington, Olivia Harder, Karthik Uppulury, William C. Stewart, Phylip Chen, Tiffany King, Susan D. Reynolds, Alan S. Perelson, Mark E. Peeples, Stefan Niewiesk, Jayajit Das	2019	20
11	No recovery of replication-competent HIV-1 from human liver macrophages Journal of Clinical Investigation ·Abraham J. Kandathil, Sho K. Sugawara, Ashish Goyal, Christine M. Durand, Jeffrey Quinn, Jaiprasath Sachithanandham, Andrew M. Cameron, Justin R. Bailey, Alan S. Perelson, Ashwin Balagopal	2018	35
12	Mathematical modeling of within‐host Zika virus dynamics Immunological Reviews ·Katharine Best, Alan S. Perelson	2018	41
13	Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence Proceedings of the National Academy of Sciences ·Ruian Ke, Hui Li, Shuyi Wang, Wenge Ding, Ruy M. Ribeiro, Elena Giorgi, Tanmoy Bhattacharya, Richard J. O. Barnard, Beatrice H. Hahn, George M. Shaw, Alan S. Perelson	2018	13
14	How Germinal Centers Evolve Broadly Neutralizing Antibodies: the Breadth of the Follicular Helper T Cell Response Journal of Virology ·Rob J. de Boer, Alan S. Perelson	2017	24
15	Modeling the Acute and Chronic Phases of Theiler Murine Encephalomyelitis Virus Infection Journal of Virology ·Jingshan Zhang, Howard L. Lipton, Alan S. Perelson, Harel Dahari	2013	12
16	Immediate antiviral therapy appears to restrict resting CD4 ⁺ cell HIV-1 infection without accelerating the decay of latent infection Proceedings of the National Academy of Sciences ·Nancie M. Archin, Naveen K. Vaidya, JoAnn D. Kuruc, Abigail Liberty, Ann Wiegand, Mary F. Kearney, Myron S. Cohen, John M. Coffin, Ronald J. Bosch, Cynthia L. Gay, Joseph J. Eron, David M. Margolis, Alan S. Perelson	2012	169
17	Modelling deuterium labelling of lymphocytes with temporal and/or kinetic heterogeneity Journal of The Royal Society Interface ·Rob J. de Boer, Alan S. Perelson, Ruy M. Ribeiro	2012	21
18	Characterizing T Cell Movement within Lymph Nodes in the Absence of Antigen The Journal of Immunology ·Catherine A. A. Beauchemin, Narendra M. Dixit, Alan S. Perelson	2007	58
19	Dose-dependent acute clearance of hepatitis C genotype 1 virus with interferon alfa Hepatology ·Natalie Lam, Avidan U. Neumann, David R. Gretch, Thelma E. Wiley, Alan S. Perelson, Thomas J. Layden	1997	283
20	Cell surface dynamics : concepts and models M. Dekker eBooks ·Alan S. Perelson, Charles DeLisi, Frederik W. Wiegel	1984	59

About Alan S. Perelson

Alan S. Perelson is a scholar working on Virology, Hepatology, Infectious Diseases, Immunology and Modeling and Simulation, having authored 521 papers that have together received 46.5k indexed citations. Recurring topics across this work include HIV Research and Treatment (194 papers), Immune Cell Function and Interaction (121 papers), Hepatitis C virus research (118 papers), T-cell and B-cell Immunology (94 papers), HIV/AIDS Research and Interventions (92 papers), HIV/AIDS drug development and treatment (85 papers), Hepatitis B Virus Studies (81 papers) and Liver Disease Diagnosis and Treatment (60 papers). The work is most often cited by research in Virology (19.7k citations), Modeling and Simulation (4.5k citations), Hepatology (7.5k citations), Infectious Diseases (14.4k citations) and Immunology (12.3k citations). Alan S. Perelson has collaborated with scholars based in United States, Netherlands and United Kingdom. Frequent co-authors include David D. Ho, Martin Markowitz, Avidan U. Neumann, Ruy M. Ribeiro, John M. Leonard, Rob J. de Boer, Patrick W. Nelson, Harel Dahari, Libin Rong and George Oster. Their work appears in journals such as Journal of Virology, Journal of Theoretical Biology, PLoS Computational Biology, Proceedings of the National Academy of Sciences and Mathematical Biosciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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