Janet D. Siliciano

25.3k total citations · 9 hit papers
104 papers, 15.9k citations indexed

About

Janet D. Siliciano is a scholar working on Virology, Infectious Diseases and Immunology. According to data from OpenAlex, Janet D. Siliciano has authored 104 papers receiving a total of 15.9k indexed citations (citations by other indexed papers that have themselves been cited), including 91 papers in Virology, 60 papers in Infectious Diseases and 45 papers in Immunology. Recurrent topics in Janet D. Siliciano's work include HIV Research and Treatment (91 papers), HIV/AIDS drug development and treatment (45 papers) and Immune Cell Function and Interaction (42 papers). Janet D. Siliciano is often cited by papers focused on HIV Research and Treatment (91 papers), HIV/AIDS drug development and treatment (45 papers) and Immune Cell Function and Interaction (42 papers). Janet D. Siliciano collaborates with scholars based in United States, Canada and Japan. Janet D. Siliciano's co-authors include Robert F. Siliciano, Daniel A. Goodenough, Bruce R. Stevenson, Mark S. Mooseker, Yoichi Taya, Christine E. Canman, Michael B. Kastan, Kazuyasu Sakaguchi, Ettore Appella and Thomas C. Quinn and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Janet D. Siliciano

101 papers receiving 15.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

1998 1.7k citations Janet D. Siliciano et al. profile →
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1999 1.6k citations Joel N. Blankson, Janet D. Siliciano et al. Nature Medicine profile →
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 1.4k citations Janet D. Siliciano et al. profile →
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells

2003 1.3k citations Janet D. Siliciano, Robert F. Siliciano et al. Nature Medicine profile →
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

2013 1.0k citations Ya‐Chi Ho, Sarah B. Laskey et al. profile →
DNA damage induces phosphorylation of the amino terminus of p53

1997 677 citations Janet D. Siliciano et al. profile →
Defective proviruses rapidly accumulate during acute HIV-1 infection

2016 515 citations Katherine M. Bruner, Alexandra J. Murray et al. Nature Medicine profile →
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

2014 391 citations C. Korin Bullen, Gregory M. Laird et al. Nature Medicine profile →
Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

2015 308 citations Gregory M. Laird, C. Korin Bullen et al. Journal of Clinical Investigation profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Janet D. Siliciano United States	53	10.2k	6.9k	5.2k	4.2k	2.0k	104	15.9k
James A. Hoxie United States	74	8.6k 0.8×	3.6k 0.5×	3.2k 0.6×	7.7k 1.8×	2.5k 1.2×	191	16.3k
Stephen C. Peiper United States	59	5.7k 0.6×	2.3k 0.3×	4.3k 0.8×	6.6k 1.6×	4.2k 2.1×	178	14.1k
Lee Ratner United States	64	8.6k 0.8×	5.4k 0.8×	4.9k 0.9×	7.1k 1.7×	2.0k 1.0×	300	17.5k
B. Matija Peterlin United States	72	7.8k 0.8×	3.6k 0.5×	8.3k 1.6×	5.1k 1.2×	1.4k 0.7×	188	15.8k
Frank Kirchhoff Germany	63	8.8k 0.9×	5.1k 0.7×	3.4k 0.7×	5.8k 1.4×	627 0.3×	296	14.0k
Patrice Debré France	69	4.7k 0.5×	3.5k 0.5×	2.5k 0.5×	10.7k 2.6×	2.1k 1.0×	390	18.2k
Jane A. McKeating United Kingdom	73	5.5k 0.5×	3.4k 0.5×	3.6k 0.7×	3.9k 0.9×	654 0.3×	232	21.0k
Mario Stevenson United States	56	8.7k 0.9×	5.2k 0.8×	4.0k 0.8×	3.7k 0.9×	548 0.3×	173	12.4k
Barbara Ensoli Italy	62	5.6k 0.5×	3.0k 0.4×	3.8k 0.7×	4.1k 1.0×	5.4k 2.6×	249	13.8k
John C. Kappes United States	54	8.8k 0.9×	4.9k 0.7×	4.0k 0.8×	4.7k 1.1×	804 0.4×	163	13.8k

Countries citing papers authored by Janet D. Siliciano

Since Specialization

Citations

This map shows the geographic impact of Janet D. Siliciano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Janet D. Siliciano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Janet D. Siliciano more than expected).

Fields of papers citing papers by Janet D. Siliciano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Janet D. Siliciano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Janet D. Siliciano. The network helps show where Janet D. Siliciano may publish in the future.

Co-authorship network of co-authors of Janet D. Siliciano

This figure shows the co-authorship network connecting the top 25 collaborators of Janet D. Siliciano. A scholar is included among the top collaborators of Janet D. Siliciano based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Janet D. Siliciano. Janet D. Siliciano is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

White, Jennifer A., Filippo Dragoni, Emily J. Fray, et al.. (2025). Superinfection promotes replication and diversification of defective HIV-1 proviruses in people with non-suppressible viraemia. Nature Microbiology. 10(11). 2736–2748.

Wu, Fengting, Srona Sengupta, Francesco R. Simonetti, et al.. (2024). Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells. Nature Immunology. 25(3). 462–470. 17 indexed citations

Dragoni, Filippo, Fengting Wu, Jun Lai, et al.. (2024). Cognate antigen engagement induces HIV-1 expression in latently infected CD4+ T cells from people on long-term antiretroviral therapy. Immunity. 57(12). 2928–2944.e6. 1 indexed citations

Wu, Fengting, et al.. (2024). CD4+ T cells with latent HIV-1 have reduced proliferative responses to T cell receptor stimulation. The Journal of Experimental Medicine. 221(3). 7 indexed citations

Sengupta, Srona, AeRyon Kim, Tatiana Boronina, et al.. (2023). A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. The Journal of Experimental Medicine. 220(7). 3 indexed citations

Fray, Emily J., Fengting Wu, Francesco R. Simonetti, et al.. (2023). Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants. Cell Host & Microbe. 31(3). 356–372.e5. 12 indexed citations

White, Jennifer A., Francesco R. Simonetti, Subul Beg, et al.. (2022). Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy. Proceedings of the National Academy of Sciences. 119(6). 52 indexed citations

Kwon, Kyungyoon J., Andrew E. Timmons, Srona Sengupta, et al.. (2020). Different human resting memory CD4 ⁺ T cell subsets show similar low inducibility of latent HIV-1 proviruses. Science Translational Medicine. 12(528). 69 indexed citations

Timmons, Andrew E., Emily J. Fray, Mithra R. Kumar, et al.. (2020). HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo. Proceedings of the National Academy of Sciences. 117(27). 15763–15771. 25 indexed citations

10.

Simonetti, Francesco R., Jennifer A. White, Camille Tumiotto, et al.. (2020). Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA. Proceedings of the National Academy of Sciences. 117(31). 18692–18700. 60 indexed citations

11.

Antar, Annukka A.R., Katharine M. Jenike, Sunyoung Jang, et al.. (2020). Longitudinal study reveals HIV-1–infected CD4+ T cell dynamics during long-term antiretroviral therapy. Journal of Clinical Investigation. 130(7). 3543–3559. 54 indexed citations

12.

Peluso, Michael J., Peter Bacchetti, Kristen D. Ritter, et al.. (2020). Differential decay of intact and defective proviral DNA in HIV-1–infected individuals on suppressive antiretroviral therapy. JCI Insight. 5(4). 124 indexed citations

13.

Simonetti, Francesco R., Hao Zhang, Kyle Rhodehouse, et al.. (2020). Antigen-driven clonal selection shapes the persistence of HIV-1–infected CD4+ T cells in vivo. Journal of Clinical Investigation. 131(3). 100 indexed citations

14.

Bertagnolli, Lynn N., Joseph Varriale, Francesco R. Simonetti, et al.. (2020). Autologous IgG antibodies block outgrowth of a substantial but variable fraction of viruses in the latent reservoir for HIV-1. Proceedings of the National Academy of Sciences. 117(50). 32066–32077. 46 indexed citations

15.

Rosenbloom, Daniel I. S., Peter Bacchetti, Mars Stone, et al.. (2019). Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size. PLoS Computational Biology. 15(4). e1006849–e1006849. 17 indexed citations

16.

Bruner, Katherine M., Alexandra J. Murray, Ross A. Pollack, et al.. (2016). Defective proviruses rapidly accumulate during acute HIV-1 infection. Nature Medicine. 22(9). 1043–1049. 515 indexed citations breakdown →

17.

Rosenbloom, Daniel I. S., Oliver Elliott, Alison L. Hill, et al.. (2015). Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1. Open Forum Infectious Diseases. 2(4). ofv123–ofv123. 94 indexed citations

18.

Siliciano, Janet D. & Robert F. Siliciano. (2013). Recent trends in HIV-1 drug resistance. Current Opinion in Virology. 3(5). 487–494. 36 indexed citations

19.

Brennan, Timothy, John O. Woods, Ahmad R. Sedaghat, et al.. (2009). Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4 ⁺ T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy. Journal of Virology. 83(17). 8470–8481. 103 indexed citations

20.

Saavedra‐Lozano, Jesús, Cynthia McCoig, Jinbo Xu, et al.. (2002). An Anti‐CD45RO Immunotoxin Kills Latently Infected Human Immunodeficiency Virus (HIV) CD4 T Cells in the Blood of HIV‐Positive Persons. The Journal of Infectious Diseases. 185(3). 306–314. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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