Adrianne Wallace-Povirk

483 citations

22 papers · 349 indexed · h-index 12

Co-authors: Zhanjun Hou Larry H. Matherly Aleem Gangjee Lisa Polin Kathryn White Juiwanna Kushner Mike R. Wilson Raymond Shapira
Topics: Folate and B Vitamins Research (13 papers)Biochemical and Molecular Research (10 papers)HIV/AIDS drug development and treatment (9 papers)
Cited by: Rheumatology Physiology Molecular Biology
Journals: Cancer Research Scientific Reports Journal of Medicinal Chemistry
Partner nations: United States China Germany

In The Last Decade

Adrianne Wallace-Povirk

21 papers receiving 347 citations

Peers

Countries citing papers authored by Adrianne Wallace-Povirk

Since Specialization

Citations

This map shows the geographic impact of Adrianne Wallace-Povirk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adrianne Wallace-Povirk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adrianne Wallace-Povirk more than expected).

Fields of papers citing papers by Adrianne Wallace-Povirk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adrianne Wallace-Povirk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adrianne Wallace-Povirk. The network helps show where Adrianne Wallace-Povirk may publish in the future.

Co-authorship network of co-authors of Adrianne Wallace-Povirk

This figure shows the co-authorship network connecting the top 25 collaborators of Adrianne Wallace-Povirk. A scholar is included among the top collaborators of Adrianne Wallace-Povirk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Adrianne Wallace-Povirk. Adrianne Wallace-Povirk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer 2024 ·Molecular Cancer Therapeutics ·Adrianne Wallace-Povirk,(unknown),(unknown),Xun Bao,(unknown),(unknown),(unknown),Jennifer Wong-Roushar,Seongho Kim,Lisa Polin,Jing Li,(unknown),Charles E. Dann,Aleem Gangjee,Zhanjun Hou,Larry H. Matherly	8
2	Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism 2023 ·ACS Pharmacology & Translational Science ·(unknown),Jennifer Wong-Roushar,Adrianne Wallace-Povirk,(unknown),(unknown),(unknown),(unknown),(unknown),Xun Bao,Seongho Kim,Jing Li,Zhanjun Hou,Larry H. Matherly,Charles E. Dann,Aleem Gangjee	6
3	Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases 2023 ·Science Translational Medicine ·(unknown),(unknown),(unknown),(unknown),Stephanie Dobersch,(unknown),Adrianne Wallace-Povirk,(unknown),(unknown),Jaeseung Kim,Angela Yu,(unknown),(unknown),Sarah Dysinger,Aaron Lampano,Faiyaz Notta,David H. Price,Andrew C. Hsieh,Sunil R. Hingorani,Sita Kugel	5
4	Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria 2023 ·Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Adrianne Wallace-Povirk,Zhanjun Hou,Larry H. Matherly,Charles E. Dann,Aleem Gangjee	7
5	Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment 2022 ·Scientific Reports ·Adrianne Wallace-Povirk,(unknown),(unknown),Sijana H. Dzinic,(unknown),(unknown),(unknown),(unknown),Zhanjun Hou,Seongho Kim,(unknown),Lisa Polin,Robert Morris,Aleem Gangjee,Heather M. Gibson,Larry H. Matherly	13
6	Folate transporter dynamics and therapy with classic and tumor-targeted antifolates 2021 ·Scientific Reports ·(unknown),Adrianne Wallace-Povirk,(unknown),(unknown),(unknown),Aleem Gangjee,Larry H. Matherly,Zhanjun Hou	21
7	Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors 2021 ·Bioorganic & Medicinal Chemistry ·Adrianne Wallace-Povirk,(unknown),Jennifer Wong-Roushar,(unknown),(unknown),Zhanjun Hou,Xun Bao,(unknown),Jing Li,Seongho Kim,Charles E. Dann,Larry H. Matherly,Aleem Gangjee	11
8	Abstract 2348: Targeting mitochondrial and cytosolic one-carbon metabolism in epithelial ovarian cancer via folate receptor alpha 2021 ·Cancer Research ·Adrianne Wallace-Povirk,(unknown),Xun Bao,(unknown),Jennifer Wong-Roushar,(unknown),Zhanjun Hou,(unknown),(unknown),(unknown),Jing Li,Seongho Kim,Lisa Polin,Charles E. Dann,Aleem Gangjee,Larry H. Matherly	2
9	Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer 2021 ·Cancers ·Adrianne Wallace-Povirk,Zhanjun Hou,(unknown),Aleem Gangjee,Larry H. Matherly	19
10	Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism 2019 ·Molecular Pharmacology ·(unknown),(unknown),(unknown),(unknown),Hasini A. Kalpage,(unknown),Adrianne Wallace-Povirk,(unknown),Zhanjun Hou,Seongho Kim,Maik Hüttemann,Aleem Gangjee,Larry H. Matherly	29
11	Abstract 4791: Impact of folate transport redundancies on the therapy with tumor-targeted and untargeted antifolates 2019 ·Cancer Research ·Zhanjun Hou,(unknown),(unknown),Adrianne Wallace-Povirk,(unknown),(unknown),Aleem Gangjee,Larry H. Matherly	0
12	Abstract 3983: Tumor-targeting with novel dual-targeted 6-substituted thieno[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α, and inhibition of de novo purine nucleotide biosynthesis 2018 ·Cancer Research ·Adrianne Wallace-Povirk,(unknown),(unknown),Zhanjun Hou,Aleem Gangjee,Larry H. Matherly,Xilin Zhou	1
13	Fluorine-Substituted Pyrrolo[2,3-d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition ofde NovoPurine Nucleotide Biosynthesis 2018 ·Journal of Medicinal Chemistry ·(unknown),Mike R. Wilson,(unknown),(unknown),Mohammad A. Karim,Lisa Polin,Adrianne Wallace-Povirk,Kathryn White,Juiwanna Kushner,Zhanjun Hou,Larry H. Matherly,Aleem Gangjee	21
14	Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3- d ]pyrimidine Antifolates 2017 ·Molecular Cancer Therapeutics ·Zhanjun Hou,(unknown),(unknown),Yang Si,Adrianne Wallace-Povirk,(unknown),(unknown),Lisa Polin,Kathryn White,Juiwanna Kushner,Robert Morris,Aleem Gangjee,Larry H. Matherly	38
15	Abstract 3309: Tumor-treating fields decrease proliferation and clonogenicity of patient-derived WHO grade IV glioma cell lines 2017 ·Cancer Research ·Sharon K. Michelhaugh,(unknown),Adrianne Wallace-Povirk,Sandeep Mittal	1
16	Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis 2016 ·Journal of Medicinal Chemistry ·Lalit K. Golani,Adrianne Wallace-Povirk,(unknown),Jennifer Wong-Roushar,Jiyuan Ke,Xin Gu,Sudhir Raghavan,Mike R. Wilson,Xinxin Li,Lisa Polin,Parker W. de Waal,Kathryn White,Juiwanna Kushner,(unknown),Zhanjun Hou,H. Eric Xu,Karsten Melcher,Charles E. Dann,Larry H. Matherly,Aleem Gangjee	28
17	6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors 2015 ·Journal of Medicinal Chemistry ·Lei Wang,Adrianne Wallace-Povirk,Sudhir Raghavan,(unknown),Mike R. Wilson,Si Yang,Lisa Polin,Kathryn White,Juiwanna Kushner,(unknown),(unknown),(unknown),Zhanjun Hou,(unknown),Charles E. Dann,Larry H. Matherly,Aleem Gangjee	35
18	Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice. 2014 ·PubMed ·Kenneth P. Mitton,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Adrianne Wallace-Povirk,(unknown),(unknown),Jason Sotzen,Trung Tran	25
19	Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α and β and the Proton-Coupled Folate Transporter 2014 ·Journal of Medicinal Chemistry ·Lalit K. Golani,(unknown),(unknown),Sudhir Raghavan,(unknown),Adrianne Wallace-Povirk,Mike R. Wilson,Zhanjun Hou,Larry H. Matherly,Aleem Gangjee	24
20	BRCA1, BRCA2 and CHEK2 c.1100 delC mutations in patients with double primaries of the breasts and/or ovaries 2010 ·Journal of Medical Genetics ·D. Gareth Evans,Mahmood Ahmed,S. C. Bayliss,Emma Howard,Fiona Lalloo,Adrianne Wallace-Povirk	5

About Adrianne Wallace-Povirk

Adrianne Wallace-Povirk is a scholar working on Rheumatology, Infectious Diseases and Physiology, having authored 22 papers that have together received 349 indexed citations. Recurring topics across this work include Folate and B Vitamins Research (13 papers), Biochemical and Molecular Research (10 papers) and HIV/AIDS drug development and treatment (9 papers). The work is most often cited by research in Rheumatology (113 citations), Physiology (17 citations) and Molecular Biology (234 citations). Adrianne Wallace-Povirk has collaborated with scholars based in United States, China and Germany. Frequent co-authors include Zhanjun Hou, Larry H. Matherly, Aleem Gangjee, Lisa Polin, Kathryn White, Juiwanna Kushner, Mike R. Wilson, Raymond Shapira, Robert F. Kibler and William C. Mobley. Their work appears in journals such as Cancer Research, Scientific Reports and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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