Larry H. Matherly

9.4k total citations
203 papers, 7.5k citations indexed

About

Larry H. Matherly is a scholar working on Molecular Biology, Rheumatology and Oncology. According to data from OpenAlex, Larry H. Matherly has authored 203 papers receiving a total of 7.5k indexed citations (citations by other indexed papers that have themselves been cited), including 128 papers in Molecular Biology, 110 papers in Rheumatology and 39 papers in Oncology. Recurrent topics in Larry H. Matherly's work include Folate and B Vitamins Research (110 papers), Biochemical and Molecular Research (44 papers) and HIV/AIDS drug development and treatment (33 papers). Larry H. Matherly is often cited by papers focused on Folate and B Vitamins Research (110 papers), Biochemical and Molecular Research (44 papers) and HIV/AIDS drug development and treatment (33 papers). Larry H. Matherly collaborates with scholars based in United States, China and Netherlands. Larry H. Matherly's co-authors include I. David Goldman, Zhanjun Hou, Jeffrey W. Taub, Yubin Ge, Aleem Gangjee, Rongbao Zhao, Johnathan R. Whetstine, So C. Wong, Yijun Deng and Robin M. Flatley and has published in prestigious journals such as Journal of Biological Chemistry, Nature Communications and Blood.

In The Last Decade

Larry H. Matherly

196 papers receiving 7.4k citations

Peers

Countries citing papers authored by Larry H. Matherly

Since Specialization

Citations

This map shows the geographic impact of Larry H. Matherly's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Larry H. Matherly with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Larry H. Matherly more than expected).

Fields of papers citing papers by Larry H. Matherly

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Larry H. Matherly. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Larry H. Matherly. The network helps show where Larry H. Matherly may publish in the future.

Co-authorship network of co-authors of Larry H. Matherly

This figure shows the co-authorship network connecting the top 25 collaborators of Larry H. Matherly. A scholar is included among the top collaborators of Larry H. Matherly based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Larry H. Matherly. Larry H. Matherly is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression 2025 ·Cancer Research Communications ·(unknown), (unknown), (unknown), A.R.W. Forrest, Zhanjun Hou, Larry H. Matherly, David M. Loeb, Antonio Di Cristofano	0
2	Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumors 2025 ·Drug Metabolism and Disposition ·(unknown), (unknown), Xun Bao, (unknown), (unknown), (unknown), Jing Li, Seongho Kim, Charles E. Dann, Aleem Gangjee, Zhanjun Hou, Larry H. Matherly	0
3	BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer 2024 ·Cancer Research Communications ·(unknown), Radhika Gogoi, (unknown), Sandra Galoforo, (unknown), (unknown), Alexandra Fox, Seongho Kim, Ramandeep Rattan, Zhanjun Hou, Robert T. Morris, Larry H. Matherly, Gil Mor, Ayesha B. Alvero	0
4	Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism 2023 ·ACS Pharmacology & Translational Science ·(unknown), Jennifer Wong-Roushar, Adrianne Wallace-Povirk, (unknown), (unknown), (unknown), (unknown), (unknown), Xun Bao, Seongho Kim, Jing Li, Zhanjun Hou, Larry H. Matherly, Charles E. Dann, Aleem Gangjee	6
5	Abstract 4902: Mitochondrial and cytosolic folylpolyglutamate synthetase in one-carbon metabolism and anti-tumor efficacy of mitochondrial-targeted antifolates 2023 ·Cancer Research ·(unknown), (unknown), (unknown), (unknown), Xun Bao, (unknown), Charles E. Dann, Aleem Gangjee, Larry H. Matherly, Zhanjun Hou	1
6	FOXQ1 recruits the MLL complex to activate transcription of EMT and promote breast cancer metastasis 2022 ·Nature Communications ·(unknown), Ling Wu, Christoph Block, Mu Zhang, Justin Hackett, Douglas B. Craig, Wei Chen, Yongzhong Zhao, Bin Zhang, Yongjun Dang, Xiaohong Zhang, Shengping Zhang, Chuangui Wang, Heather M. Gibson, Lori A. Pile, Benjamin L. Kidder, Larry H. Matherly, Zhe Yang, Yali Dou, Guojun Wu	24
7	Chronic p27Kip1 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor 2018 ·Scientific Reports ·(unknown), (unknown), Rayna Rosati, Yanfang Huang, (unknown), Lisa Polin, (unknown), Mike R. Wilson, Fulvio Lonardo, (unknown), Jing Li, Larry H. Matherly, Gerold Bepler, Manohar Ratnam	10
8	Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3- d ]pyrimidine Antifolates 2017 ·Molecular Cancer Therapeutics ·Zhanjun Hou, (unknown), (unknown), Yang Si, Adrianne Wallace-Povirk, (unknown), (unknown), Lisa Polin, Kathryn White, Juiwanna Kushner, Robert Morris, Aleem Gangjee, Larry H. Matherly	38
9	Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools 2017 ·Annals of Oncology ·Elisa Giovannetti, Paolo Andrea Zucali, Yehuda G. Assaraf, Niccola Funel, Maria Gemelli, Michal Stark, Erik Thunnissen, Zhanjun Hou, (unknown), Eduard A. Struys, Matteo Perrino, Gerrit Jansen, Larry H. Matherly, Godefridus J. Peters	37
10	Glucocorticoid Receptor Status Is a Principal Determinant of Variability in the Sensitivity of Non–Small-Cell Lung Cancer Cells to Pemetrexed 2014 ·Journal of Thoracic Oncology ·(unknown), Shirish M. Gadgeel, Yanfang Huang, (unknown), Anthony F. Shields, Larry H. Matherly, Gerold Bepler, Manohar Ratnam	25
11	Notch1 Receptor Regulates AKT Protein Activation Loop (Thr308) Dephosphorylation through Modulation of the PP2A Phosphatase in Phosphatase and Tensin Homolog (PTEN)-null T-cell Acute Lymphoblastic Leukemia Cells 2013 ·Journal of Biological Chemistry ·(unknown), (unknown), Amanda Larson Gedman, Jeffrey W. Taub, Larry H. Matherly	43
12	Implications of Plasma Protein Binding for Pharmacokinetics and Pharmacodynamics of the γ-Secretase Inhibitor RO4929097 2012 ·Clinical Cancer Research ·Jianmei Wu, Patricia LoRusso, Larry H. Matherly, Jing Li	17
13	Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter 2012 ·Molecular Pharmacology ·Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee, Larry H. Matherly	27
14	Chapter 5 Structure and Function of the Reduced Folate Carrier 2008 ·Vitamins and hormones ·Larry H. Matherly, Zhanjun Hou	66
15	A humanized mouse model for the reduced folate carrier 2007 ·Molecular Genetics and Metabolism ·David Patterson, Christine M. Graham, Christina Cherian, Larry H. Matherly	12
16	Molecular and cellular biology of the human reduced folate carrier 2001 ·Progress in nucleic acid research and molecular biology ·Larry H. Matherly	76
17	The Basal Promoters for the Human Reduced Folate Carrier Gene Are Regulated by a GC-box and a cAMP-response Element/AP-1-like Element 2001 ·Journal of Biological Chemistry ·Johnathan R. Whetstine, Larry H. Matherly	40
18	Human k562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity 1997 ·Biochemical Pharmacology ·So C. Wong, (unknown), (unknown), Alok Bhushan, Larry H. Matherly	38
19	The cellular pharmacology of methotrexate 1985 ·Pharmacology & Therapeutics ·I. David Goldman, Larry H. Matherly	221
20	Role of the cellular oxidation-reduction state in methotrexate binding to dihydrofolate reductase and dissociation induced by reduced folates. 1984 ·PubMed ·Larry H. Matherly, Linda A. Anderson, I. David Goldman	20

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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