Adam J. de Smith

6.9k citations

108 papers · 3.3k · 1 hit paper · h-index 29

Impact in

Biochemistry top 2%
- Phytochemicals and Antioxidant Activities
Genetics top 2%
- Genomic variations and chromosomal abnormalities
- Genetic Syndromes and Imprinting
- Genomics and Rare Diseases

Papers in

Molecular Biology 48
- Epigenetics and DNA Methylation 28
- RNA modifications and cancer 7
Public Health, Environmental and Occupational Health 38
- Acute Lymphoblastic Leukemia research 34

Co-authors: Alexandra I. F. Blakemore (14 shared papers)Joseph L. Wiemels (62 shared papers)Philippe Froguel (10 shared papers)J Baker (1 shared paper)D. Fyfe (1 shared paper)David A. Anderson (1 shared paper)D. Ferry (1 shared paper)Rachel Kerr (1 shared paper)
Journals: Blood (11 papers)Human Molecular Genetics (5 papers)Cancer Epidemiology Biomarkers & Prevention (4 papers)Leukemia (4 papers)Blood Advances (4 papers)
Partner nations: United States United Kingdom France

In The Last Decade

Adam J. de Smith

102 papers receiving 3.3k citations

Adam J. de Smith's Hit Papers

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Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. 1996 · 538 citations

Peers

Countries citing papers authored by Adam J. de Smith

Since Specialization

Citations

This map shows the geographic impact of Adam J. de Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adam J. de Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adam J. de Smith more than expected).

Fields of papers citing papers by Adam J. de Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adam J. de Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adam J. de Smith. The network helps show where Adam J. de Smith may publish in the future.

Co-authors

The 25 scholars most cited alongside Adam J. de Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Adam J. de Smith Line = papers co-authored together Adam J. de Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 108 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. PubMed ·D. Ferry, Adam J. de Smith, J Malkhandi, D. Fyfe, P G deTakats, David A. Anderson, J Baker, Rachel Kerr Hit paper breakdown →	1996	538
2	FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity Nature Genetics ·Manuela Fanciulli, Penny J. Norsworthy, Enrico Petretto, Rong Dong, Lorraine Harper, Lavanya Kamesh, J. M. Heward, Stephen Gough, Adam J. de Smith, Alexandra I. F. Blakemore, Philippe Froguel, Catherine Owen, Simon H. S. Pearce, Luís Teixeira, Loı̈c Guillevin, Deborah S. Cunninghame Graham, Charles D. Pusey, H. Terence Cook, Timothy J. Vyse, Timothy J. Aitman	2007	354
3	A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism Human Molecular Genetics ·Adam J. de Smith, Carolin Purmann, Robin Walters, Richard J. Ellis, Susan Holder, Mieke M. van Haelst, A. F. Brady, U. L. Fairbrother, Mehul Dattani, Julia M. Keogh, Elana Henning, Giles S.H. Yeo, Stephen O’Rahilly, Philippe Froguel, I. Sadaf Farooqi, Alexandra I. F. Blakemore	2009	218
4	Array CGH analysis of copy number variation identifies 1284 new genes variant in healthy white males: implications for association studies of complex diseases Human Molecular Genetics ·Adam J. de Smith, Anya Tsalenko, Nick Sampas, Alicia Scheffer, N. Alice Yamada, Peter Tsang, Amir Ben‐Dor, Zohar Yakhini, Richard J. Ellis, Laurakay Bruhn, Stephen Laderman, Philippe Froguel, Alexandra I. F. Blakemore	2007	176
5	Green Tea Epigallocatechin-3-Gallate (EGCG) and Other Flavonoids Reduce Alzheimer's Amyloid-Induced Mitochondrial Dysfunction Journal of Alzheimer s Disease ·Natasa Dragicevic, Adam J. de Smith, Xiaoyang Lin, Fang Yuan, Neil Copes, Vedad Delic, Jun Tan, Chuanhai Cao, R. Douglas Shytle, Patrick C. Bradshaw	2011	150
6	Luteolin Reduces Alzheimer’s Disease Pathologies Induced by Traumatic Brain Injury International Journal of Molecular Sciences ·Darrell Sawmiller, Song Li, Md Shahaduzzaman, Adam J. de Smith, Demian Obregon, Brian Giunta, Cesar V. Borlongan, Paul R. Sanberg, Jun Tan	2014	128
7	PDGFRα demarcates the cardiogenic clonogenic Sca1+ stem/progenitor cell in adult murine myocardium Nature Communications ·Michela Noseda, Mutsuo Harada, Sara J. McSweeney, Thomas Leja, Elisa Belian, Daniel J. Stuckey, Marta Paiva, (unknown), Iain C. Macaulay, Adam J. de Smith, Farah Al-Beidh, Robert D. Sampson, R Thomas Lumbers, Pulivarthi H. Rao, Siân E. Harding, Alexandra I. F. Blakemore, Sten Eirik W. Jacobsen, Mauricio Barahona, Michael Schneider	2015	110
8	A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network Nucleic Acids Research ·Seung‐Tae Lee, Yuanyuan Xiao, Marcus O. Muench, Jianqiao Xiao, Marina E. Fomin, John K. Wiencke, Shichun Zheng, Xiaoqin Dou, Adam J. de Smith, Anand P. Chokkalingam, Patricia A. Buffler, Xiaomei Ma, Joseph L. Wiemels	2012	85
9	Humoral factors in ALS patients during disease progression Journal of Neuroinflammation ·Jared Ehrhart, Adam J. de Smith, Nicole Kuzmin‐Nichols, Theresa Zesiewicz, Israt Jahan, R. Douglas Shytle, Seol-Hee Kim, Cyndy D. Sanberg, Tuan Vu, Clifton L. Gooch, Paul R. Sanberg, Svitlana Garbuzova‐Davis	2015	85
10	Diosmin reduces cerebral Aβ levels, tau hyperphosphorylation, neuroinflammation, and cognitive impairment in the 3xTg-AD mice Journal of Neuroimmunology ·Darrell Sawmiller, Ahsan Habib, Song Li, Donna Darlington, Huayan Hou, Jun Tian, R. Douglas Shytle, Adam J. de Smith, Brian Giunta, T. Mori, Jun Tan	2016	74
11	Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases Neuropathology and Applied Neurobiology ·Claudio Ruffmann, Federico C. F. Calboli, Ilaria Bravi, Djordje Gverić, L. K. Curry, Adam J. de Smith, Sofia Pavlou, J. L. Buxton, Alexandra I. F. Blakemore, Petros Takousis, Sophie Molloy, Paola Piccini, D. T. Dexter, Federico Roncaroli, Steve Gentleman, Lefkos Middleton	2015	72
12	GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21 Nature Communications ·Joseph L. Wiemels, Kyle M. Walsh, Adam J. de Smith, Catherine Metayer, Semira Gonseth, Helen M. Hansen, Stephen Francis, Juhi Ojha, Ivan Smirnov, Lisa F. Barcellos, Xiaorong Xiao, Libby M. Morimoto, Roberta McKean‐Cowdin, Rong Wang, Herbert Yu, Josephine Hoh, Andrew T. DeWan, Xiaomei Ma	2018	71
13	Imprinted expression of UBE3A in non-neuronal cells from a Prader–Willi syndrome patient with an atypical deletion Human Molecular Genetics ·Kristen Martins‐Taylor, Jack S. Hsiao, Pin-Fang Chen, Heather R. Glatt-Deeley, Adam J. de Smith, Alexandra I. F. Blakemore, Marc Lalande, Stormy J. Chamberlain	2013	53
14	In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia Blood ·Stephen Francis, Amelia D. Wallace, George A. Wendt, Linlin Li, Fenyong Liu, Lee W. Riley, Scott C. Kogan, Kyle M. Walsh, Adam J. de Smith, Gary V. Dahl, Xiaomei Ma, Eric Delwart, Catherine Metayer, Joseph L. Wiemels	2016	52
15	Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease Cytogenetic and Genome Research ·Adam J. de Smith, Robin Walters, Philippe Froguel, Alexandra I. F. Blakemore	2008	52
16	Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia Cancer Epidemiology Biomarkers & Prevention ·Juhi Ojha, Veryan Codd, Christopher P. Nelson, Nilesh J. Samani, Ivan Smirnov, Nils R. Madsen, Helen M. Hansen, Adam J. de Smith, Paige M. Bracci, John K. Wiencke, Margaret Wrensch, Joseph L. Wiemels, Kyle M. Walsh	2016	51
17	Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers Carcinogenesis ·Kyle M. Walsh, Todd P. Whitehead, Adam J. de Smith, Ivan Smirnov, Minsun Park, Alyson Endicott, Stephen Francis, Veryan Codd, Nilesh J. Samani, Catherine Metayer, Joseph L. Wiemels	2016	48
18	Small Deletion Variants Have Stable Breakpoints Commonly Associated with Alu Elements PLoS ONE ·Adam J. de Smith, Robin Walters, Lachlan Coin, Israel Steinfeld, Zohar Yakhini, Robert Sladek, Philippe Froguel, Alexandra I. F. Blakemore	2008	44
19	The role of KIR genes and their cognate HLA class I ligands in childhood acute lymphoblastic leukemia Blood ·Adam J. de Smith, Kyle M. Walsh, Martha Ladner, Siming Zhang, Carmen Xiao, Franziska Cohen, Theodore B. Moore, Anand P. Chokkalingam, Catherine Metayer, Patricia A. Buffler, Elizabeth Trachtenberg, Joseph L. Wiemels	2014	36
20	Variant to function mapping at single-cell resolution through network propagation Nature Biotechnology ·Fulong Yu, Liam D. Cato, Chen Weng, L. Alexander Liggett, Soyoung Jeon, Keren Xu, Charleston W. K. Chiang, Joseph L. Wiemels, Jonathan S. Weissman, Adam J. de Smith, Vijay G. Sankaran	2022	36

About Adam J. de Smith

Adam J. de Smith is a scholar working on Molecular Biology, Public Health, Environmental and Occupational Health, Genetics, Pediatrics, Perinatology and Child Health and Physiology, having authored 108 papers that have together received 3.3k indexed citations. Recurring topics across this work include Acute Lymphoblastic Leukemia research (34 papers), Epigenetics and DNA Methylation (28 papers), Childhood Cancer Survivors' Quality of Life (18 papers), Genomic variations and chromosomal abnormalities (14 papers), Alzheimer's disease research and treatments (7 papers), RNA modifications and cancer (7 papers), Acute Myeloid Leukemia Research (6 papers) and Genomics and Rare Diseases (6 papers). The work is most often cited by research in Biochemistry (190 citations), Genetics (796 citations), Biological Psychiatry (60 citations), Molecular Biology (1.3k citations) and Pediatrics, Perinatology and Child Health (314 citations). Adam J. de Smith has collaborated with scholars based in United States, United Kingdom and France. Frequent co-authors include Alexandra I. F. Blakemore, Joseph L. Wiemels, Philippe Froguel, J Baker, D. Fyfe, David A. Anderson, D. Ferry, Rachel Kerr, Catherine Metayer and Kyle M. Walsh. Their work appears in journals such as Blood, Human Molecular Genetics, Cancer Epidemiology Biomarkers & Prevention, Leukemia and Blood Advances.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Adam J. de Smith

Adam J. de Smith's Hit Papers

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