Ralf C. Kling

2.3k total citations · 2 hit papers
20 papers, 1.8k citations indexed

About

Ralf C. Kling is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Oncology. According to data from OpenAlex, Ralf C. Kling has authored 20 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 14 papers in Cellular and Molecular Neuroscience and 4 papers in Oncology. Recurrent topics in Ralf C. Kling's work include Receptor Mechanisms and Signaling (16 papers), Neuropeptides and Animal Physiology (14 papers) and Chemical Synthesis and Analysis (7 papers). Ralf C. Kling is often cited by papers focused on Receptor Mechanisms and Signaling (16 papers), Neuropeptides and Animal Physiology (14 papers) and Chemical Synthesis and Analysis (7 papers). Ralf C. Kling collaborates with scholars based in Germany, United Kingdom and United States. Ralf C. Kling's co-authors include Peter Gmeiner, Brian K. Kobilka, Aashish Manglik, Harald Hübner, Stefan Löber, Ron O. Dror, Adrian L. Sanborn, Hideaki Kato, AJ Venkatakrishnan and Toon Laeremans and has published in prestigious journals such as Nature, Angewandte Chemie International Edition and PLoS ONE.

In The Last Decade

Ralf C. Kling

20 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structural insights into µ-opioid receptor activation

2015 700 citations Weijiao Huang, Aashish Manglik et al. Nature profile →
Structure-based discovery of opioid analgesics with reduced side effects

2016 697 citations Aashish Manglik, Henry J. Lin et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ralf C. Kling Germany	12	1.6k	1.2k	257	185	158	20	1.8k
Eyal Vardy United States	15	1.9k 1.2×	1.5k 1.2×	254 1.0×	242 1.3×	117 0.7×	26	2.4k
Thor S. Thorsen Denmark	12	1.1k 0.7×	734 0.6×	122 0.5×	128 0.7×	68 0.4×	18	1.3k
Richard B. Westkaemper United States	20	1.8k 1.1×	1.5k 1.2×	228 0.9×	130 0.7×	169 1.1×	43	2.3k
Kathryn E. Livingston United States	11	979 0.6×	802 0.7×	117 0.5×	111 0.6×	92 0.6×	13	1.1k
Stefan Löber Germany	23	1.4k 0.9×	806 0.7×	185 0.7×	159 0.9×	146 0.9×	49	2.1k
Paul Leff United Kingdom	16	1.8k 1.1×	1.2k 1.0×	102 0.4×	99 0.5×	280 1.8×	26	2.6k
Gayathri Swaminath United States	17	1.8k 1.1×	1.0k 0.9×	121 0.5×	148 0.8×	180 1.1×	28	2.4k
Céline Valant Australia	29	3.0k 1.9×	1.9k 1.6×	521 2.0×	393 2.1×	110 0.7×	70	3.4k
Christian Tränkle Germany	32	2.1k 1.3×	1.3k 1.1×	253 1.0×	194 1.0×	115 0.7×	73	2.8k

Countries citing papers authored by Ralf C. Kling

Since Specialization

Citations

This map shows the geographic impact of Ralf C. Kling's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ralf C. Kling with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ralf C. Kling more than expected).

Fields of papers citing papers by Ralf C. Kling

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ralf C. Kling. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ralf C. Kling. The network helps show where Ralf C. Kling may publish in the future.

Co-authorship network of co-authors of Ralf C. Kling

This figure shows the co-authorship network connecting the top 25 collaborators of Ralf C. Kling. A scholar is included among the top collaborators of Ralf C. Kling based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ralf C. Kling. Ralf C. Kling is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Huang, Weijiao, Aashish Manglik, AJ Venkatakrishnan, et al.. (2020). Author Correction: Structural insights into μ-opioid receptor activation. Nature. 584(7820). E16–E16. 8 indexed citations

Kling, Ralf C., et al.. (2019). Structure-based exploration of an allosteric binding pocket in the NTS1 receptor using bitopic NT(8-13) derivatives and molecular dynamics simulations. Journal of Molecular Modeling. 25(7). 193–193. 3 indexed citations

Wifling, David, Christopher Pfleger, Jonas Kaindl, et al.. (2019). Basal Histamine H₄ Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif. Chemistry - A European Journal. 25(64). 14613–14624. 7 indexed citations

Kling, Ralf C., Timothy Clark, & Peter Gmeiner. (2016). Comparative MD Simulations Indicate a Dual Role for Arg1323.50 in Dopamine-Dependent D2R Activation. PLoS ONE. 11(1). e0146612–e0146612. 10 indexed citations

Manglik, Aashish, Henry J. Lin, Dipendra K. Aryal, et al.. (2016). Structure-based discovery of opioid analgesics with reduced side effects. Nature. 537(7619). 185–190. 697 indexed citations breakdown →

Simeth, Nadja A., Ralf C. Kling, Harald Hübner, et al.. (2016). NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids. Bioorganic & Medicinal Chemistry. 25(1). 350–359. 8 indexed citations

Saleh, Noureldin, et al.. (2016). Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3. Angewandte Chemie. 128(49). 15503–15507. 6 indexed citations

Kling, Ralf C., et al.. (2016). Development of Covalent Ligand–Receptor Pairs to Study the Binding Properties of Nonpeptidic Neurotensin Receptor 1 Antagonists. ACS Chemical Biology. 11(4). 869–875. 17 indexed citations

Saleh, Noureldin, et al.. (2016). Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3. Angewandte Chemie International Edition. 55(49). 15277–15281. 20 indexed citations

10.

Huang, Weijiao, Aashish Manglik, AJ Venkatakrishnan, et al.. (2015). Structural insights into µ-opioid receptor activation. Nature. 524(7565). 315–321. 700 indexed citations breakdown →

11.

Möller, Dorothée, Ismail Salama, Ralf C. Kling, Harald Hübner, & Peter Gmeiner. (2015). 1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation. Bioorganic & Medicinal Chemistry. 23(18). 6195–6209. 15 indexed citations

12.

Weichert, Dietmar, et al.. (2015). Molecular Determinants of Biased Agonism at the Dopamine D₂Receptor. Journal of Medicinal Chemistry. 58(6). 2703–2717. 37 indexed citations

13.

Möller, Dorothée, et al.. (2014). Functionally Selective Dopamine D ₂ , D ₃ Receptor Partial Agonists. Journal of Medicinal Chemistry. 57(11). 4861–4875. 69 indexed citations

14.

Kling, Ralf C., Jürgen Einsiedel, Harald Hübner, et al.. (2014). Structure‐Based Evolution of Subtype‐Selective Neurotensin Receptor Ligands. ChemistryOpen. 3(5). 206–218. 11 indexed citations

15.

Shonberg, Jeremy, Ralf C. Kling, Peter Gmeiner, & Stefan Löber. (2014). GPCR crystal structures: Medicinal chemistry in the pocket. Bioorganic & Medicinal Chemistry. 23(14). 3880–3906. 93 indexed citations

16.

Kling, Ralf C., Nuška Tschammer, Harald Lanig, Timothy Clark, & Peter Gmeiner. (2014). Active-State Model of a Dopamine D2 Receptor - Gαi Complex Stabilized by Aripiprazole-Type Partial Agonists. PLoS ONE. 9(6). e100069–e100069. 30 indexed citations

17.

Kling, Ralf C., Harald Lanig, Timothy Clark, & Peter Gmeiner. (2013). Active-State Models of Ternary GPCR Complexes: Determinants of Selective Receptor-G-Protein Coupling. PLoS ONE. 8(6). e67244–e67244. 36 indexed citations

18.

Hübner, Harald, et al.. (2013). Impact of the Proline Residue on Ligand Binding of Neurotensin Receptor 2 (NTS2)‐Selective Peptide–Peptoid Hybrids. ChemMedChem. 8(5). 772–778. 17 indexed citations

19.

Kling, Ralf C., et al.. (2013). Functionally Selective Dopamine D₂/D₃Receptor Agonists Comprising an Enyne Moiety. Journal of Medicinal Chemistry. 56(12). 5130–5141. 51 indexed citations

20.

Kling, Ralf C., et al.. (1975). [The effect of anti-convulsive long term treatment on serum concentration of alkaline phosphatase, calcium, magnesium and inorganic phosphates in children].. PubMed. 156–60. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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