A. De Léan

5.6k total citations · 2 hit papers
69 papers, 4.7k citations indexed

About

A. De Léan is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, A. De Léan has authored 69 papers receiving a total of 4.7k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 29 papers in Cardiology and Cardiovascular Medicine and 23 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in A. De Léan's work include Receptor Mechanisms and Signaling (23 papers), Heart Failure Treatment and Management (18 papers) and Hormonal Regulation and Hypertension (14 papers). A. De Léan is often cited by papers focused on Receptor Mechanisms and Signaling (23 papers), Heart Failure Treatment and Management (18 papers) and Hormonal Regulation and Hypertension (14 papers). A. De Léan collaborates with scholars based in Canada, United States and France. A. De Léan's co-authors include Robert J. Lefkowitz, Jeffrey M. Stadel, Arthur A. Hancock, M. Cantin, Jacques Drouin, Huy Ong, David R. Sibley, Ian Creese, Fernand Labrie and Jolanta Gutkowska and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

A. De Léan

69 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

1980 1.3k citations A. De Léan et al. Journal of Biological Chemistry profile →
Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.

1982 552 citations A. De Léan et al. Molecular Pharmacology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
A. De Léan Canada	31	3.2k	2.0k	835	711	381	69	4.7k
M G Caron United States	37	5.3k 1.7×	3.3k 1.7×	452 0.5×	553 0.8×	963 2.5×	48	6.6k
R J Lefkowitz United States	24	3.1k 1.0×	1.9k 1.0×	318 0.4×	329 0.5×	589 1.5×	29	4.1k
L E Limbird United States	36	3.0k 1.0×	1.8k 0.9×	454 0.5×	275 0.4×	579 1.5×	60	4.4k
R.J. Lefkowitz United States	25	4.3k 1.4×	2.8k 1.4×	387 0.5×	345 0.5×	737 1.9×	39	5.4k
Erin J. Whalen United States	29	4.0k 1.3×	2.1k 1.1×	800 1.0×	285 0.4×	796 2.1×	48	5.2k
Antonio De Blasi Italy	38	3.3k 1.0×	2.7k 1.3×	385 0.5×	227 0.3×	565 1.5×	101	5.4k
Kristen L. Pierce United States	25	5.1k 1.6×	2.5k 1.3×	329 0.4×	340 0.5×	537 1.4×	36	6.5k
C C Malbon United States	39	3.1k 1.0×	1.2k 0.6×	202 0.2×	544 0.8×	1.1k 2.8×	81	4.5k
Magalì Waelbroeck Belgium	38	3.7k 1.2×	3.5k 1.8×	245 0.3×	589 0.8×	375 1.0×	184	5.0k
Éric Reiter France	38	4.2k 1.3×	2.2k 1.1×	322 0.4×	722 1.0×	273 0.7×	103	5.8k

Countries citing papers authored by A. De Léan

Since Specialization

Citations

This map shows the geographic impact of A. De Léan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. De Léan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. De Léan more than expected).

Fields of papers citing papers by A. De Léan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. De Léan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. De Léan. The network helps show where A. De Léan may publish in the future.

Co-authorship network of co-authors of A. De Léan

This figure shows the co-authorship network connecting the top 25 collaborators of A. De Léan. A scholar is included among the top collaborators of A. De Léan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. De Léan. A. De Léan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Bodart, V., William E. Rainey, Alain Fournier, Hui Xin Ong, & A. De Léan. (1996). The H295R human adrenocortical cell line contains functional atrial natriuretic peptide receptors that inhibit aldosterone biosynthesis. Molecular and Cellular Endocrinology. 118(1-2). 137–144. 27 indexed citations

Babinski, Kazimierz, V. Bodart, M. Roy, A. De Léan, & Hui Xin Ong. (1996). Pituitary adenylate-cyclase activating polypeptide (PACAP) evokes long-lasting secretion and de novo biosynthesis of bovine adrenal medullary neuropeptides. Neuropeptides. 30(6). 572–582. 36 indexed citations

Babinski, Kazimierz, Pierre S. Haddad, Diane Vallerand, et al.. (1995). Natriuretic Peptides Inhibit Nicotine‐Induced Whole‐Cell Currents and Catecholamine Secretion in Bovine Chromaffin Cells: Evidence for the Involvement of the Atrial Natriuretic Factor R₂ Receptors. Journal of Neurochemistry. 64(3). 1080–1087. 20 indexed citations

Mimeault, Murielle, Alain Fournier, James Féthière, & A. De Léan. (1993). Development of natriuretic peptide analogs selective for the atrial natriuretic factor-R1A receptor subtype.. Molecular Pharmacology. 43(5). 775–782. 10 indexed citations

Féthière, James, et al.. (1993). Distribution and regulation of natriuretic factor-R1C receptor subtypes in mammalian cell lines. Molecular and Cellular Biochemistry. 124(1). 11–16. 14 indexed citations

Babinski, Kazimierz, James Féthière, M. Roy, A. De Léan, & Hui Xin Ong. (1992). C‐type natriuretic peptide in bovine chromaffin cells The regulation of its biosynthesis and secretion. FEBS Letters. 313(3). 300–302. 11 indexed citations

Larose, Louise, et al.. (1992). Phosphorylation of atrial natriuretic factor R1 receptor by serine/threonine protein kinases: evidences for receptor regulation. Molecular and Cellular Biochemistry. 115(2). 203–211. 49 indexed citations

Féthière, James & A. De Léan. (1991). Pharmacological Evidence for the Heterogeneity of Atrial Natriuretic Factor-R1 Receptor Subtype. Molecular Pharmacology. 40(6). 915–922. 12 indexed citations

Marleau, Sylvie, et al.. (1991). Role of the endopeptidase 24.11 in the disposition and metabolism of endogenous atrial natriuretic factor in the rabbit.. Drug Metabolism and Disposition. 19(1). 194–199. 4 indexed citations

10.

Aumont, Nicole, et al.. (1990). IL-3 inhibits the binding of GM-CSF to AML blasts, but the two cytokines act synergistically in supporting blast proliferation.. PubMed. 4(5). 329–36. 28 indexed citations

11.

Aumont, Nicole, et al.. (1990). Characterization of granulocyte-macrophage colony-stimulating factor receptor on the blast cells of acute myeloblastic leukemia. Blood. 75(1). 59–66. 42 indexed citations

12.

Féthière, James, Sylvain Meloche, Tina Nguyen, Hui Xin Ong, & A. De Léan. (1989). Distinct properties of atrial natriuretic factor receptor subpopulations in epithelial and fibroblast cell lines.. Molecular Pharmacology. 35(5). 584–592. 43 indexed citations

13.

Lazure, Claude, et al.. (1989). ALDOSTERONE SECRETION INHIBITORY FACTOR: A NOVEL NEUROPEPTIDE IN BOVINE CHROMAFFIN CELLS. Endocrinology. 124(3). 1591–1593. 26 indexed citations

14.

Lazure, Claude, Huy Ong, Normand McNicoll, et al.. (1988). The amino acid sequences of frog heart atrial natriuretic‐like peptide and mammalian ANF are closely related. FEBS Letters. 238(2). 300–306. 44 indexed citations

15.

Gutkowska, Jolanta, Jacques Genest, Gaétan Thibault, et al.. (1987). Circulating Forms and Radioimmunoassay of Atrial Natriuretic Factor. Endocrinology and Metabolism Clinics of North America. 16(1). 183–198. 46 indexed citations

16.

Meloche, Sylvain, Huy Ong, & A. De Léan. (1987). Functional heterogeneity of atrial natriuretic factor receptor in bovine adrenal zona glomerulosa is explained by an amiloride-sensitive high affinity molecular complex.. Journal of Biological Chemistry. 262(21). 10252–10258. 40 indexed citations

17.

Léan, A. De, et al.. (1987). Analysis of the kinetics of ovine follitropin agonist-antagonist interactions with pig ovarian membranes. Biochemistry. 26(12). 3650–3658. 9 indexed citations

18.

Rácz, K., Otto Kuchel, M. Cantin, & A. De Léan. (1985). Atrial natriuretic factor inhibits the early pathway of steroid biosynthesis in bovine adrenal cortex. FEBS Letters. 192(1). 19–22. 39 indexed citations

19.

Thibault, Gaétan, R. García, Jolanta Gutkowska, et al.. (1985). Biochemical aspects of a new hormone: Rat atrial natriuretic factor (rANF). Regulatory Peptides. 10. 131–135. 3 indexed citations

20.

Drouin, Jacques, et al.. (1976). Characteristics of the Interaction Between Thyrotropin-Releasing Hormone and Somatostatin for Thyrotropin and Prolactin Release. Endocrinology. 98(2). 514–521. 94 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact