Standout Papers

Ferroptosis as a p53-mediated activity du... 2001 2026 2009 2017 2.4k
  1. Ferroptosis as a p53-mediated activity during tumour suppression (2015)
    Le Jiang, Ning Kon et al. Nature
  2. Negative Control of p53 by Sir2α Promotes Cell Survival under Stress (2001)
    Jianyuan Luo, Anatoly Nikolaev et al. Cell
  3. Ferroptosis as a target for protection against cardiomyopathy (2019)
    Xuexian Fang, Hao Wang et al. Proceedings of the National Academy of Sciences
  4. Modes of p53 Regulation (2009)
    Wei Gu et al. Cell
  5. Mammalian SIRT1 Represses Forkhead Transcription Factors (2004)
    Maria Carla Motta, Nullin Divecha et al. Cell
  6. Emerging Mechanisms and Disease Relevance of Ferroptosis (2020)
    Brent R. Stockwell, Xuejun Jiang et al. Trends in Cell Biology
  7. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization (2002)
    Muyang Li, Delin Chen et al. Nature
  8. Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence (2012)
    Tongyuan Li, Ning Kon et al. Cell
  9. p53 Ubiquitination: Mdm2 and Beyond (2006)
    Christopher Brooks, Wei Gu Molecular Cell
  10. Deacetylation of p53 modulates its effect on cell growth and apoptosis (2000)
    Jianyuan Luo, Fei Su et al. Nature
  11. ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway (2019)
    Bo Chu, Ning Kon et al. Nature Cell Biology
  12. Acetylation Is Indispensable for p53 Activation (2008)
    Yi Tang, Wenhui Zhao et al. Cell
  13. Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ (2012)
    Li Qiang, Liheng Wang et al. Cell
  14. Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2 (2003)
    Muyang Li, Christopher Brooks et al. Science
  15. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation (2003)
    Christopher Brooks, Wei Gu Current Opinion in Cell Biology
  16. Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses (2016)
    Yang Ou, Shang-Jui Wang et al. Proceedings of the National Academy of Sciences
  17. Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones (2007)
    Yue Chen, Robert W. Sprung et al. Molecular & Cellular Proteomics
  18. SIRT1 transgenic mice show phenotypes resembling calorie restriction (2007)
    Laura Bordone, Dena E. Cohen et al. Aging Cell
  19. Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis (2006)
    Yi Tang, Jianyuan Luo et al. Molecular Cell
  20. Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses (2005)
    Wenyong Chen, David H. Wang et al. Cell
  21. A Dynamic Role of HAUSP in the p53-Mdm2 Pathway (2004)
    Muyang Li, Christopher Brooks et al. Molecular Cell
  22. SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice (2008)
    Alexander S. Banks, Ning Kon et al. Cell Metabolism
  23. Non-transcriptional control of DNA replication by c-Myc (2007)
    David Dominguez-Sola, Carol Y. Ying et al. Nature
  24. Crystal Structure of a UBP-Family Deubiquitinating Enzyme in Isolation and in Complex with Ubiquitin Aldehyde (2002)
    Min Hu, Pingwei Li et al. Cell
  25. The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11 (2019)
    Tong Liu, Le Jiang et al. Cancer Research
  26. Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression (2016)
    Dawei Li, Yang Ou et al. Cell Reports
  27. p53 in ferroptosis regulation: the new weapon for the old guardian (2022)
    Yanqing Liu, Wei Gu Cell Death and Differentiation
  28. Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones (2023)
    Deguang Liang, Yan Feng et al. Cell
  29. p53 modifications: exquisite decorations of the powerful guardian (2019)
    Yanqing Liu, Omid Tavana et al. Journal of Molecular Cell Biology
  30. iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4 (2021)
    Delin Chen, Bo Chu et al. Nature Communications
  31. Understanding the complexity of p53 in a new era of tumor suppression (2024)
    Yanqing Liu, Zhenyi Su et al. Cancer Cell
  32. Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis (2024)
    Baiyu Qiu, Fereshteh Zandkarimi et al. Cell
  33. Tryptophan Metabolism Acts as a New Anti‐Ferroptotic Pathway to Mediate Tumor Growth (2023)
    Dong Liu, Chunhui Liang et al. Advanced Science

Immediate Impact

3 by Nobel laureates 63 from Science/Nature 233 standout
Sub-graph 1 of 13

Citing Papers

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2023 StandoutScience
15 intermediate papers

Works of Wei Gu being referenced

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
2008 Standout
Negative regulation of the deacetylase SIRT1 by DBC1
2008 Nature
and 11 more

Author Peers

Author Last Decade Papers Cites
Wei Gu 23558 9955 8429 185 34.2k
Marcia C. Haigis 13415 3383 5532 124 24.0k
Eileen White 26157 7439 8316 239 40.3k
Reuben J. Shaw 20255 3128 5228 85 29.5k
Junjie Chen 26405 9619 6467 377 31.8k
John Blenis 38903 8109 5551 221 51.3k
Jason W. Locasale 15830 3876 8997 181 23.9k
Eric W.‐F. Lam 15136 5354 3995 297 22.8k
Simone Fulda 20107 5548 4706 392 26.9k
Brendan D. Manning 21580 3854 4801 113 30.2k
Nissim Hay 19923 4807 6359 159 27.4k

All Works

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