Wei Gu

49.0k total citations · 35 hit papers
188 papers, 35.2k citations indexed

About

Wei Gu is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Wei Gu has authored 188 papers receiving a total of 35.2k indexed citations (citations by other indexed papers that have themselves been cited), including 146 papers in Molecular Biology, 83 papers in Oncology and 47 papers in Cancer Research. Recurrent topics in Wei Gu's work include Cancer-related Molecular Pathways (72 papers), Ubiquitin and proteasome pathways (60 papers) and Epigenetics and DNA Methylation (42 papers). Wei Gu is often cited by papers focused on Cancer-related Molecular Pathways (72 papers), Ubiquitin and proteasome pathways (60 papers) and Epigenetics and DNA Methylation (42 papers). Wei Gu collaborates with scholars based in United States, China and Canada. Wei Gu's co-authors include Christopher Brooks, Delin Chen, Ning Kon, Muyang Li, Le Jiang, Richard Baer, Shang-Jui Wang, Tongyuan Li, Yingming Zhao and Anatoly Nikolaev and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Wei Gu

184 papers receiving 34.8k citations

Hit Papers

Ferroptosis as a p53-mediated activi... 2000 2026 2008 2017 2015 2001 2019 2009 2004 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Ferroptosis as a p53-mediated activity during tumour suppression
    2015 2.5k citations Le Jiang, Ning Kon et al. Nature profile →
  2. Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
    2001 1.8k citations Jianyuan Luo, Delin Chen et al. profile →
  3. Ferroptosis as a target for protection against cardiomyopathy
    2019 1.6k citations Wei Gu et al. profile →
  4. Modes of p53 Regulation
    2009 1.3k citations Wei Gu et al. profile →
  5. Mammalian SIRT1 Represses Forkhead Transcription Factors
    2004 1.1k citations Delin Chen, Wei Gu et al. profile →
  6. Emerging Mechanisms and Disease Relevance of Ferroptosis
    2020 842 citations Wei Gu et al. profile →
  7. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
    2002 810 citations Muyang Li, Delin Chen et al. Nature profile →
  8. Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence
    2012 735 citations Ning Kon, Le Jiang et al. profile →
  9. p53 Ubiquitination: Mdm2 and Beyond
    2006 713 citations Christopher Brooks, Wei Gu profile →
  10. ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway
    2019 704 citations Bo Chu, Ning Kon et al. profile →
  11. Deacetylation of p53 modulates its effect on cell growth and apoptosis
    2000 681 citations Jianyuan Luo, Fei Su et al. Nature profile →
  12. Acetylation Is Indispensable for p53 Activation
    2008 680 citations Wei Gu et al. profile →
  13. Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
    2012 666 citations Ning Kon, Wei Gu et al. profile →
  14. Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses
    2016 622 citations Yang Ou, Shang-Jui Wang et al. profile →
  15. Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2
    2003 622 citations Muyang Li, Christopher Brooks et al. profile →
  16. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
    2003 620 citations Christopher Brooks, Wei Gu profile →
  17. Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones
    2007 592 citations Wei Gu et al. profile →
  18. SIRT1 transgenic mice show phenotypes resembling calorie restriction
    2007 587 citations Wei Gu et al. profile →
  19. Tip60-Dependent Acetylation of p53 Modulates the Decision between Cell-Cycle Arrest and Apoptosis
    2006 574 citations Wei Gu et al. profile →
  20. Tumor Suppressor HIC1 Directly Regulates SIRT1 to Modulate p53-Dependent DNA-Damage Responses
    2005 530 citations Wei Gu et al. profile →
  21. A Dynamic Role of HAUSP in the p53-Mdm2 Pathway
    2004 527 citations Muyang Li, Christopher Brooks et al. profile →
  22. SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
    2008 526 citations Ning Kon, Wei Gu et al. profile →
  23. Non-transcriptional control of DNA replication by c-Myc
    2007 519 citations Muyang Li, Wei Gu et al. Nature profile →
  24. Crystal Structure of a UBP-Family Deubiquitinating Enzyme in Isolation and in Complex with Ubiquitin Aldehyde
    2002 515 citations Muyang Li, Wei Gu et al. profile →
  25. Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
    2023 407 citations Wei Gu et al. profile →
  26. p53 in ferroptosis regulation: the new weapon for the old guardian
    2022 379 citations Wei Gu et al. profile →
  27. The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11
    2019 379 citations Tong Liu, Le Jiang et al. Cancer Research profile →
  28. Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression
    2016 364 citations Yang Ou, Le Jiang et al. Cell Reports profile →
  29. p53 modifications: exquisite decorations of the powerful guardian
    2019 289 citations Omid Tavana, Wei Gu et al. profile →
  30. iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4
    2021 259 citations Delin Chen, Bo Chu et al. Nature Communications profile →
  31. Understanding the complexity of p53 in a new era of tumor suppression
    2024 187 citations Yanqing Liu, Zhenyi Su et al. Cancer Cell profile →
  32. The complexity of p53-mediated metabolic regulation in tumor suppression
    2021 180 citations Wei Gu et al. profile →
  33. Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis
    2024 178 citations Wei Gu et al. profile →
  34. Tryptophan Metabolism Acts as a New Anti‐Ferroptotic Pathway to Mediate Tumor Growth
    2023 107 citations Dong Liu, Chunhui Liang et al. Advanced Science profile →
  35. p53-regulated non-apoptotic cell death pathways and their relevance in cancer and other diseases
    2025 16 citations Wei Gu et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Wei Gu United States 81 24.1k 10.1k 8.6k 7.6k 5.7k 188 35.2k
Marcia C. Haigis United States 65 13.7k 0.6× 3.5k 0.3× 5.7k 0.7× 1.2k 0.2× 6.6k 1.2× 128 24.7k
Reuben J. Shaw United States 53 20.6k 0.9× 3.2k 0.3× 5.3k 0.6× 1.4k 0.2× 1.3k 0.2× 85 30.3k
Simone Fulda Germany 82 20.4k 0.8× 5.6k 0.6× 4.8k 0.6× 1.8k 0.2× 722 0.1× 395 27.4k
Eric W.‐F. Lam United Kingdom 87 15.3k 0.6× 5.4k 0.5× 4.0k 0.5× 1.3k 0.2× 1.0k 0.2× 298 23.1k
Brendan D. Manning United States 62 22.0k 0.9× 3.9k 0.4× 4.9k 0.6× 2.0k 0.3× 452 0.1× 118 30.9k
Nissim Hay United States 75 20.2k 0.8× 4.9k 0.5× 6.5k 0.8× 1.7k 0.2× 338 0.1× 160 27.9k
Xuejun Jiang United States 64 18.6k 0.8× 3.3k 0.3× 9.0k 1.0× 11.2k 1.5× 279 0.0× 171 28.7k
Mikhail V. Blagosklonny United States 81 12.7k 0.5× 5.6k 0.6× 3.3k 0.4× 1.1k 0.1× 592 0.1× 243 19.8k
Jan M. van Deursen United States 60 13.3k 0.6× 4.1k 0.4× 2.8k 0.3× 1.1k 0.1× 720 0.1× 116 26.1k
Boudewijn Burgering Netherlands 64 17.6k 0.7× 3.9k 0.4× 2.7k 0.3× 557 0.1× 1.3k 0.2× 155 22.7k

Countries citing papers authored by Wei Gu

Since Specialization
Citations

This map shows the geographic impact of Wei Gu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wei Gu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wei Gu more than expected).

Fields of papers citing papers by Wei Gu

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wei Gu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wei Gu. The network helps show where Wei Gu may publish in the future.

Co-authorship network of co-authors of Wei Gu

This figure shows the co-authorship network connecting the top 25 collaborators of Wei Gu. A scholar is included among the top collaborators of Wei Gu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wei Gu. Wei Gu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chen, Hao, Cole Ferguson, Dylan C. Mitchell, et al.. (2025). The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway. Cell Reports. 44(2). 115231–115231. 6 indexed citations
2.
3.
Liu, Yanqing, Zhenyi Su, Omid Tavana, & Wei Gu. (2024). Understanding the complexity of p53 in a new era of tumor suppression. Cancer Cell. 42(6). 946–967. 187 indexed citations breakdown →
4.
Kabir, Md, Xiao Hu, Tiphaine Martin, et al.. (2024). Harnessing the TAF1 Acetyltransferase for Targeted Acetylation of the Tumor Suppressor p53. Advanced Science. 12(7). e2413377–e2413377. 2 indexed citations
5.
Su, Zhenyi, Ning Kon, Jingjie Yi, et al.. (2023). Specific regulation of BACH1 by the hotspot mutant p53R175H reveals a distinct gain-of-function mechanism. Nature Cancer. 4(4). 564–581. 36 indexed citations
6.
Liu, Dong, Chunhui Liang, Bin Huang, et al.. (2023). Tryptophan Metabolism Acts as a New Anti‐Ferroptotic Pathway to Mediate Tumor Growth. Advanced Science. 10(6). e2204006–e2204006. 107 indexed citations breakdown →
7.
Miao, Zong, Wei Tian, Yangfan Ye, et al.. (2022). Hsp90 induces Acsl4-dependent glioma ferroptosis via dephosphorylating Ser637 at Drp1. Cell Death and Disease. 13(6). 548–548. 72 indexed citations
8.
Kon, Ning, Michael Churchill, Huan Li, et al.. (2020). Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function. Cancer Research. 81(4). 935–944. 18 indexed citations
9.
Kon, Ning, Yang Ou, Shang-Jui Wang, et al.. (2020). mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression. Genes & Development. 35(1-2). 59–64. 41 indexed citations
10.
Kim, Jung‐Min, Kwang Hwan Park, Xianpeng Ge, et al.. (2020). A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nature Communications. 11(1). 2289–2289. 70 indexed citations
11.
Liu, Tong, Le Jiang, Omid Tavana, & Wei Gu. (2019). The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11. Cancer Research. 79(8). 1913–1924. 379 indexed citations breakdown →
12.
Yang, Xin, Zhe Wang, Xin Li, et al.. (2017). SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation. Cancer Research. 78(2). 372–386. 162 indexed citations
13.
Gu, Wei, et al.. (2013). Histone Modifications of Notch1 Promoter Affect Lung CD4+ T Cell Differentiation in Asthmatic Rats. International Journal of Immunopathology and Pharmacology. 26(2). 371–381. 21 indexed citations
14.
Chen, Delin, Jing Shan, Wei‐Guo Zhu, Jun Qin, & Wei Gu. (2010). Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses. Nature. 464(7288). 624–627. 127 indexed citations
15.
Gu, Wei, et al.. (2010). Urinary proteomics as a novel tool for biomarker discovery in kidney diseases. Journal of Zhejiang University SCIENCE B. 11(4). 227–237. 52 indexed citations
16.
Lee, Hye-Ra, Zsolt Tóth, Young C. Shin, et al.. (2009). Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 4 Targets MDM2 To Deregulate the p53 Tumor Suppressor Pathway. Journal of Virology. 83(13). 6739–6747. 62 indexed citations
17.
Abida, Wassim & Wei Gu. (2008). p53-Dependent and p53-Independent Activation of Autophagy by ARF. Cancer Research. 68(2). 352–357. 86 indexed citations
18.
Brooks, Christopher, Muyang Li, & Wei Gu. (2007). Mechanistic Studies of MDM2-mediated Ubiquitination in p53 Regulation. Journal of Biological Chemistry. 282(31). 22804–22815. 35 indexed citations
19.
Bouras, Toula, Maofu Fu, Anthony A. Sauve, et al.. (2005). SIRT1 Deacetylation and Repression of p300 Involves Lysine Residues 1020/1024 within the Cell Cycle Regulatory Domain 1. Journal of Biological Chemistry. 280(11). 10264–10276. 283 indexed citations
20.
Luo, Jianyuan, et al.. (2000). Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature. 408(6810). 377–381. 681 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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