Standout Papers

MicroRNA expression profiles classify human cancers 1992 2026 2003 2014 7.7k
  1. MicroRNA expression profiles classify human cancers (2005)
    Jun Lü, Gad Getz et al. Nature
  2. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals (2009)
    Mitchell Guttman, Ido Amit et al. Nature
  3. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia (1992)
    Wafik S. El‐Deiry, France Carrier et al. Cell
  4. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents (1993)
    Scott W. Lowe, H. Earl Ruley et al. Cell
  5. p53 is required for radiation-induced apoptosis in mouse thymocytes (1993)
    Scott W. Lowe, Earlene M. Schmitt et al. Nature
  6. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours (1996)
    Thomas G. Graeber, Tyler Jacks et al. Nature
  7. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse (2003)
    Sunil R. Hingorani, Emanuel F. Petricoin et al. Cancer Cell
  8. A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response (2010)
    Maite Huarte, Mitchell Guttman et al. Cell
  9. Tumor spectrum analysis in p53-mutant mice (1994)
    Tyler Jacks, Lee Ann Remington et al. Current Biology
  10. Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer (2005)
    Carla F. Bender Kim, Erica L. Jackson et al. Cell
  11. Effects of an Rb mutation in the mouse (1992)
    Tyler Jacks, Amin Fazeli et al. Nature
  12. Restoration of p53 function leads to tumour regression in vivo (2007)
    Andrea Ventura, David G. Kirsch et al. Nature
  13. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras (2001)
    Erica L. Jackson, Nicholas A. Willis et al. Genes & Development
  14. Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters (2008)
    Andrea Ventura, Amanda Young et al. Cell
  15. p53 Status and the Efficacy of Cancer Therapy in Vivo (1994)
    Scott W. Lowe, Stephan Bodis et al. Science
  16. Sunburn and p53 in the onset of skin cancer (1994)
    Annemarie Ziegler, Alan S. Jonason et al. Nature
  17. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 (1992)
    Laura R. Livingstone, Alicia White et al. Cell
  18. Radiation-induced cell cycle arrest compromised by p21 deficiency (1995)
    James Brugarolas, Chitra Chandrasekaran et al. Nature
  19. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. (1995)
    Kay F. Macleod, Norelle L. Sherry et al. Genes & Development
  20. Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome (2004)
    Kenneth P. Olive, David A. Tuveson et al. Cell
  21. Treating metastatic cancer with nanotechnology (2011)
    Avi Schroeder, Daniel A. Heller et al. Nature reviews. Cancer
  22. Somatic activation of the K-ras oncogene causes early onset lung cancer in mice (2001)
    Leisa Johnson, Kim L. Mercer et al. Nature
  23. p53-Dependent apoptosis suppresses tumor growth and progression in vivo (1994)
    Holly Symonds, Leonard Krall et al. Cell
  24. Characterization of ribosomal frameshifting in HIV-1 gag-pol expression (1988)
    Tyler Jacks, Michael D. Power et al. Nature
  25. MicroRNAs and Cancer: Short RNAs Go a Long Way (2009)
    Andrea Ventura, Tyler Jacks Cell
  26. Suppression of non-small cell lung tumor development by the let-7 microRNA family (2008)
    Madhu Kumar, Stefan J. Erkeland et al. Proceedings of the National Academy of Sciences
  27. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells (2019)
    Chengcheng Jin, Georgia Lagoudas et al. Cell
  28. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage (2002)
    Elsa R. Flores, Kenneth Y. Tsai et al. Nature
  29. Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects (2004)
    David A. Tuveson, Alice T. Shaw et al. Cancer Cell
  30. Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1 (1996)
    Lili Yamasaki, Tyler Jacks et al. Cell
  31. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 (1994)
    Tyler Jacks, T. Shane Shih et al. Nature Genetics
  32. Role for the p53 homologue p73 in E2F-1-induced apoptosis (2000)
    Meredith S. Irwin, María C. Marín et al. Nature
  33. Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase (2009)
    Michel DuPage, Alison L. Dooley et al. Nature Protocols
  34. CRISPR-mediated direct mutation of cancer genes in the mouse liver (2014)
    Wen Xue, Sidi Chen et al. Nature
  35. KRAS and YAP1 Converge to Regulate EMT and Tumor Survival (2014)
    Diane D. Shao, Wen Xue et al. Cell
  36. Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer (2016)
    Thales Papagiannakopoulos, Benjamin A. Olenchock et al. Cell Metabolism
  37. STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications (2001)
    David A. Tuveson, Nicholas A. Willis et al. Oncogene
  38. Signals for ribosomal frameshifting in the rous sarcoma virus gag-pol region (1988)
    Tyler Jacks, Hiten D. Madhani et al. Cell
  39. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens (1994)
    Sharon D. Morgenbesser, Bart O. Williams et al. Nature
  40. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis (2013)
    Jessie Yanxiang Guo, Gizem Karsli-Uzunbas et al. Genes & Development
  41. Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance (2014)
    Gizem Karsli-Uzunbas, Jessie Yanxiang Guo et al. Cancer Discovery
  42. Tissue of origin dictates branched-chain amino acid metabolism in mutantKras-driven cancers (2016)
    Jared R. Mayers, Margaret E. Torrence et al. Science
  43. Expression of the Rous Sarcoma Virus pol Gene by Ribosomal Frameshifting (1985)
    Tyler Jacks, Harold E Varmus Science
  44. Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6 (2017)
    Joo‐Hyeon Lee, Tuomas Tammela et al. Cell
  45. SOX17 enables immune evasion of early colorectal adenomas and cancers (2024)
    Norihiro Goto, Peter M.K. Westcott et al. Nature

Immediate Impact

52 by Nobel laureates 116 from Science/Nature 287 standout
Sub-graph 1 of 16

Citing Papers

One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Neoantigens in cancer immunotherapy
2015 StandoutScience
5 intermediate papers

Works of Tyler Jacks being referenced

Expression of tumour-specific antigens underlies cancer immunoediting
2012 Nature
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
and 3 more

Author Peers

Author Last Decade Papers Cites
Tyler Jacks 58358 33760 26145 336 86.1k
Judah Folkman 62209 24238 29198 391 103.7k
Ronald A. DePinho 55409 22760 13587 416 84.9k
Scott W. Lowe 49438 22670 16688 324 68.3k
Kenneth W. Kinzler 78978 48789 37023 377 130.0k
Joan Massagué 94714 46583 22328 356 135.6k
Roderick T. Bronson 45554 22954 11505 543 76.8k
Zena Werb 45042 34757 33138 411 108.4k
Napoleone Ferrara 60705 20350 23583 257 97.7k
Carlos Cordon‐Cardo 40955 22560 12688 563 67.3k
Raghu Kalluri 48220 20553 24773 315 80.9k

All Works

Loading papers...

Rankless by CCL
2026