Standout Papers

The Protein Kinase Complement of the Human Genome 1988 2026 2000 2013 6.1k
  1. The Protein Kinase Complement of the Human Genome (2002)
    Gerard Manning, Tony Hunter et al. Science
  2. The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains (1988)
    Steven K. Hanks, Anne Marie Quinn et al. Science
  3. Oncogenic kinase signalling (2001)
    Peter Blume‐Jensen, Tony Hunter Nature
  4. Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling (1995)
    Tony Hunter Cell
  5. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. (1995)
    Steven K. Hanks, Tony Hunter PubMed
  6. Signaling—2000 and Beyond (2000)
    Tony Hunter Cell
  7. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine (1980)
    Tony Hunter, Bartholomew M. Sefton Proceedings of the National Academy of Sciences
  8. PROTEIN-TYROSINE KINASES (1985)
    Tony Hunter, Jonathan A. Cooper Annual Review of Biochemistry
  9. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age (1994)
    Tony Hunter, Jonathon Pines Cell
  10. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 (1994)
    Hideo Toyoshima, Tony Hunter Cell
  11. Protein Tyrosine Phosphatases in the Human Genome (2004)
    Andrés Alonso, Joanna M. Sasin et al. Cell
  12. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase (1994)
    David D. Schlaepfer, Steven K. Hanks et al. Nature
  13. [11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates (1991)
    William J. Boyle, Peter van der Geer et al. Methods in enzymology on CD-ROM/Methods in enzymology
  14. The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes (1988)
    Robert Chiu, William J. Boyle et al. Cell
  15. [42] Detection and quantification of phosphotyrosine in proteins (1983)
    Jonathan A. Cooper, Bartholomew M. Sefton et al. Methods in enzymology on CD-ROM/Methods in enzymology
  16. The regulation of transcription by phosphorylation (1992)
    Tony Hunter, Michael Karin Cell
  17. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1 (1999)
    William Biggs, Jill Meisenhelder et al. Proceedings of the National Academy of Sciences
  18. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity (1991)
    William J. Boyle, Tod Smeal et al. Cell
  19. A thousand and one protein kinases (1987)
    Tony Hunter Cell
  20. The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase (1999)
    Claudio A.P. Joazeiro, Simon S. Wing et al. Science
  21. Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro (1989)
    Jill Meisenhelder, Pann‐Ghill Suh et al. Cell
  22. Oncogene jun encodes a sequence-specific trans- activator similar to AP-1 (1988)
    Peter Angel, Elizabeth A. Allegretto et al. Nature
  23. Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein (1984)
    W. Kruijer, Jonathan A. Cooper et al. Nature
  24. Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2 (1989)
    Jonathon Pines, Tony Hunter Cell
  25. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. (1991)
    Jonathon Pines, Tony Hunter The Journal of Cell Biology
  26. The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond (2007)
    Tony Hunter Molecular Cell
  27. Phosphorylation of β-Catenin by AKT Promotes β-Catenin Transcriptional Activity (2007)
    Dexing Fang, David H. Hawke et al. Journal of Biological Chemistry
  28. The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor (1991)
    Dan Soppet, Enrique Escandón et al. Cell
  29. Evolution of protein kinase signaling from yeast to man (2002)
    Gerard Manning, Gregory D. Plowman et al. Trends in Biochemical Sciences
  30. trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. (1991)
    David S. Middlemas, Richard Lindberg et al. Molecular and Cellular Biology
  31. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B (1990)
    Jonathon Pines, Tony Hunter Nature
  32. PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis (2012)
    Weiwei Yang, Yan Xia et al. Cell
  33. Cooperation between oncogenes (1991)
    Tony Hunter Cell
  34. Inappropriate Activation of the TSC/Rheb/mTOR/S6K Cassette Induces IRS1/2 Depletion, Insulin Resistance, and Cell Survival Deficiencies (2004)
    O. Jameel Shah, Zhiyong Wang et al. Current Biology
  35. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus (1995)
    Michael Karin, Tony Hunter Current Biology
  36. C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. (1984)
    Claude Cochet, Gordon N. Gill et al. Journal of Biological Chemistry
  37. Structural basis for phosphoserine-proline recognition by group IV WW domains. (2000)
    Mark A. Verdecia, M.E. Bowman et al. Nature Structural Biology
  38. Cyclins and cancer (1991)
    Tony Hunter, Jonathon Pines Cell
  39. Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent (1997)
    Rama Ranganathan, Kun Ping Lu et al. Cell
  40. Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells (1981)
    Tony Hunter, Jonathan A. Cooper Cell
  41. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane (1984)
    Tony Hunter, Nicholas Ling et al. Nature
  42. Tyrosine phosphorylation: thirty years and counting (2009)
    Tony Hunter Current Opinion in Cell Biology
  43. Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion (2003)
    Zhimin Lu, Sourav Ghosh et al. Cancer Cell
  44. Structure-based prediction of protein–protein interactions on a genome-wide scale (2012)
    Qiangfeng Cliff Zhang, Donald Petrey et al. Nature
  45. Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus (1980)
    Bartholomew M. Sefton, Tony Hunter et al. Cell
  46. Tyr 527 Is Phosphorylated in pp60 c- src : Implications for Regulation (1986)
    Jonathan A. Cooper, Kathleen L. Gould et al. Science
  47. Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation (2016)
    Xinde Zheng, Leah Boyer et al. eLife
  48. An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates (1979)
    Walter Eckhart, M A Hutchinson et al. Cell
  49. Messenger RNA for the coat protein of tobacco mosaic virus (1976)
    Tony Hunter, Tim Hunt et al. Nature
  50. The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates (1975)
    Tony Hunter, Tim Hunt et al. Journal of Biological Chemistry

Immediate Impact

70 by Nobel laureates 100 from Science/Nature 183 standout
Sub-graph 1 of 17

Citing Papers

Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
15 intermediate papers

Works of Tony Hunter being referenced

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003 Standout
Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification.
1995 Standout
and 6 more

Author Peers

Author Last Decade Papers Cites
Tony Hunter 77156 23136 17369 502 103.0k
Lewis C. Cantley 103801 27070 19466 702 148.2k
John C. Reed 72596 21174 9970 788 106.2k
Joseph Schlessinger 67577 24781 16283 524 95.5k
Roger J. Davis 61987 15513 11605 563 91.7k
Steven P. Gygi 87120 12298 17827 689 119.3k
Tony Pawson 49380 10872 13014 446 67.8k
Ruedi Aebersold 85496 8964 9708 776 115.8k
Philip Cohen 67060 9697 13461 488 88.5k
Joan Massagué 94714 46583 12573 356 135.6k
Douglas Hanahan 78402 43041 9385 224 134.4k

All Works

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