Standout Papers

Adhesion receptors of the immune system 1986 2026 1999 2012 5.6k
  1. Adhesion receptors of the immune system (1990)
    Timothy A. Springer Nature
  2. Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). (1986)
    Michael L. Dustin, Robert Rothlein et al. The Journal of Immunology
  3. Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins (1991)
    Michael B. Lawrence, Timothy A. Springer Cell
  4. Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1) (1987)
    Steven D. Marlin, Timothy A. Springer Cell
  5. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice (1998)
    Qing Ma, Dan Jones et al. Proceedings of the National Academy of Sciences
  6. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1 (1989)
    Michael L. Dustin, Timothy A. Springer Nature
  7. Traffic Signals on Endothelium for Lymphocyte Recirculation and Leukocyte Emigration (1995)
    Timothy A. Springer Annual Review of Physiology
  8. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) (1996)
    Conrad C. Bleul, Robert C. Fuhlbrigge et al. The Journal of Experimental Medicine
  9. Structural Basis of Integrin Regulation and Signaling (2007)
    Bing‐Hao Luo, Christopher V. Carman et al. Annual Review of Immunology
  10. Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. (1986)
    Jordan S. Pober, Michael A. Gimbrone et al. The Journal of Immunology
  11. The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood (1997)
    Alessandro Aiuti, Iain J. Webb et al. The Journal of Experimental Medicine
  12. Mac‐1: a macrophage differentiation antigen identified by monoclonal antibody (1979)
    Timothy A. Springer, G. Galfré et al. European Journal of Immunology
  13. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. (1994)
    Stephen J. Roth, Ed Luther et al. Proceedings of the National Academy of Sciences
  14. The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System (1987)
    Timothy A. Springer, Michael L. Dustin et al. Annual Review of Immunology
  15. Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling (2002)
    Junichi Takagi, Benjamin M. Petre et al. Cell
  16. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes (1997)
    Conrad C. Bleul, Lijun Wu et al. Proceedings of the National Academy of Sciences
  17. LEUKOCYTE ADHESION DEFICIENCY: An Inherited Defect in the Mac-1, LFA-1, and p150,95 Glycoproteins (1987)
    D. C. Anderson, Timothy A. Springer Annual Review of Medicine
  18. Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. (1988)
    Michael L. Dustin, Timothy A. Springer The Journal of Cell Biology
  19. Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families (1988)
    Donald E. Staunton, Steven D. Marlin et al. Cell
  20. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN- gamma production. (1988)
    Martin E. Sanders, Malegapuru W. Makgoba et al. The Journal of Immunology
  21. Latent TGF-β structure and activation (2011)
    Minlong Shi, Jianghai Zhu et al. Nature
  22. A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule. (1983)
    Francisco Sánchez‐Madrid, Janice A. Nagy et al. The Journal of Experimental Medicine
  23. ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18). (1990)
    Michael Diamond, Donald E. Staunton et al. The Journal of Cell Biology
  24. Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1 (1989)
    Donald E. Staunton, Michael L. Dustin et al. Nature
  25. Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation (1991)
    Michael Diamond, Donald E. Staunton et al. Cell
  26. Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. (1982)
    Francisco Sánchez‐Madrid, Alan M. Krensky et al. Proceedings of the National Academy of Sciences
  27. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics (2004)
    Tsan Sam Xiao, Junichi Takagi et al. Nature
  28. Bidirectional Transmembrane Signaling by Cytoplasmic Domain Separation in Integrins (2003)
    Minsoo Kim, Christopher V. Carman et al. Science
  29. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. (1996)
    Katherine J. Kelly, W. W. Williams et al. Journal of Clinical Investigation
  30. Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1). (1988)
    Michael L. Dustin, K H Singer et al. The Journal of Experimental Medicine
  31. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. (1995)
    R. Alon, Paul D. Kassner et al. The Journal of Cell Biology
  32. The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus (1990)
    Donald E. Staunton, Michael L. Dustin et al. Cell
  33. Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow (1995)
    R. Alon, Daniel A. Hammer et al. Nature
  34. The Chemokine Receptor CXCR4 Is Required for the Retention of B Lineage and Granulocytic Precursors within the Bone Marrow Microenvironment (1999)
    Qing Ma, Dan Jones et al. Immunity
  35. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens (1978)
    Timothy A. Springer, G. Galfré et al. European Journal of Immunology
  36. Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor. (1982)
    D I Beller, Timothy A. Springer et al. The Journal of Experimental Medicine
  37. ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells (1988)
    Malegapuru W. Makgoba, Martin E. Sanders et al. Nature
  38. A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. (1981)
    Arkajyoti Bhattacharya, Martin E. Dorf et al. The Journal of Immunology
  39. The Severe and Moderate Phenotypes of Heritable Mac-1, LFA-1 Deficiency: Their Quantitative Definition and Relation to Leukocyte Dysfunction and Clinical Features (1985)
    D C Anderson, F. C. Schmalsteig et al. The Journal of Infectious Diseases
  40. The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions. (1983)
    Alan M. Krensky, Francisco Sánchez‐Madrid et al. The Journal of Immunology
  41. von Willebrand factor, Jedi knight of the bloodstream (2014)
    Timothy A. Springer Blood

Immediate Impact

15 by Nobel laureates 127 from Science/Nature 240 standout
Sub-graph 1 of 15

Citing Papers

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151 intermediate papers

Works of Timothy A. Springer being referenced

Intact αIIbβ3 Integrin Is Extended after Activation as Measured by Solution X-ray Scattering and Electron Microscopy
2011
Latent TGF-β structure and activation
2011 StandoutNature
and 126 more

Author Peers

Author Last Decade Papers Cites
Timothy A. Springer 42631 43166 16248 25767 531 90.5k
Richard O. Hynes 30808 11600 5666 32993 360 72.2k
Erkki Ruoslahti 31552 9167 10906 43554 464 90.4k
Eugene C. Butcher 15966 31675 4878 12306 336 52.9k
Klaus Ley 13069 26490 2474 16001 449 54.7k
Michael L. Dustin 11861 31452 6565 13074 380 51.3k
Joseph Schlessinger 7002 12507 14006 67577 524 95.5k
Irving L. Weissman 4829 46620 5839 58306 826 129.3k
George D. Yancopoulos 6302 15739 7552 54500 425 101.4k
David A. Cheresh 18070 6447 4993 28065 241 48.0k
Zena Werb 12155 18208 3298 45042 411 108.4k

All Works

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