Standout Papers

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functi... 1986 2026 1999 2012 6.2k
  1. TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties (1989)
    Tim R. Mosmann, Robert L. Coffman Annual Review of Immunology
  2. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. (1986)
    Timothy R. Mosmann, Holly Cherwinski et al. The Journal of Immunology
  3. Interleukin-10 and the Interleukin-10 Receptor (2001)
    Kevin W. Moore, René de Waal Malefyt et al. Annual Review of Immunology
  4. Vaccine Adjuvants: Putting Innate Immunity to Work (2010)
    Robert L. Coffman, Alan Sher et al. Immunity
  5. An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation (1999)
    Chrystelle Asseman, Smita Mauze et al. The Journal of Experimental Medicine
  6. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. (1989)
    Frederick P. Heinzel, M D Sadick et al. The Journal of Experimental Medicine
  7. Lymphokine Control of In Vivo Immunoglobulin Isotype Selection (1990)
    F D Finkelman, J M Holmes et al. Annual Review of Immunology
  8. Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus (2011)
    Gina Stella García-Romo, Simone Caielli et al. Science Translational Medicine
  9. Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells (1989)
    Robert L. Coffman et al. Advances in immunology
  10. Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells (1994)
    Fiona Powrie, Michael W. Leach et al. Immunity
  11. In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines (2002)
    Franck J. Barrat, J. Daniel et al. The Journal of Experimental Medicine
  12. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice (1993)
    Fiona Powrie, Michael W. Leach et al. International Immunology
  13. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells (1988)
    Tracy L. Stevens, A Bossie et al. Nature
  14. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. (1996)
    Fiona Powrie, J A Carlino et al. The Journal of Experimental Medicine
  15. Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines (1992)
    Ali Sher, Robert L. Coffman Annual Review of Immunology
  16. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus (2005)
    Franck J. Barrat, Josh Gregorio et al. The Journal of Experimental Medicine
  17. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists (2007)
    Holger Kanzler, Franck J. Barrat et al. Nature Medicine
  18. Two types of mouse helper T-cell clone (1987)
    Tim R. Mosmann, Robert L. Coffman Immunology Today
  19. B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. (1986)
    Robert L. Coffman, J Ohara et al. The Journal of Immunology
  20. The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation (1988)
    Robert L. Coffman, Brian W. P. Seymour et al. Immunological Reviews
  21. IFN- gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses. (1988)
    Fred D. Finkelman, Ildy M. Katona et al. The Journal of Immunology
  22. A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma. (1986)
    Robert L. Coffman, J E Carty The Journal of Immunology
  23. Ordered rearrangement of immunoglobulin heavy chain variable region segments. (1984)
    Frederick W. Alt, George D. Yancopoulos et al. The EMBO Journal
  24. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. (1988)
    Phillip Scott, P Natovitz et al. The Journal of Experimental Medicine
  25. Antibody to Interleukin-5 Inhibits Helminth-Induced Eosinophilia in Mice (1989)
    Robert L. Coffman, Brian W. P. Seymour et al. Science
  26. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. (1994)
    Fiona Powrie, Rodrigo Corrêa‐Oliveira et al. The Journal of Experimental Medicine
  27. Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9 (2016)
    Irma García‐Martinez, Nicola Santoro et al. Journal of Clinical Investigation

Immediate Impact

30 by Nobel laureates 82 from Science/Nature 162 standout
Sub-graph 1 of 17

Citing Papers

Bile acid metabolites control TH17 and Treg cell differentiation
2019 StandoutNature
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
9 intermediate papers

Works of Robert L. Coffman being referenced

A Restricted Subset of Dendritic Cells Captures Airborne Antigens and Remains Able to Activate Specific T Cells Long after Antigen Exposure
2002
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice
1993 Standout
and 8 more

Author Peers

Author Last Decade Papers Cites
Robert L. Coffman 39139 8948 4131 8691 254 60.2k
Anne O’Garra 35564 9307 1369 8120 209 54.2k
Giorgio Trinchieri 46473 10147 2587 12816 431 66.6k
Siamon Gordon 40753 10477 2573 21755 453 76.9k
Antonio Lanzavecchia 57125 9519 5272 12884 346 76.1k
Bruce Beutler 37780 10744 1471 17041 401 63.8k
Richard M. Locksley 32137 8792 736 7746 268 50.6k
Charles R. Mackay 25357 3863 2288 12173 251 46.2k
Nico van Rooijen 37722 12972 3242 21141 836 79.3k
Federica Sallusto 40897 7063 1736 8833 239 54.6k
Jacques Banchereau 61797 6994 4814 16129 475 79.5k

All Works

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